Controlled release of 5-fluorouridine from radiation-crosslinked poly(ethylene-co-vinyl acetate) films

Acta Biomaterialia

Volumn 2, Issue 6, 2006, Pages 641-650

  de Queiroz, Alvaro A A ^a   Abraham, Gustavo A ^b   Higa, Olga Zazuco ^c  

^a FEDERAL UNIVERSITY OF ITAJUBÁ   (Brazil)

^b Instituto de Investigaciones en Ciencia y Tecnologia de Materiales   (Argentina)

^c INSTITUTO DE PESQUISAS ENERGÉTICAS E NUCLEARES   (Brazil)

Author keywords

5 Fluorouridine; Cancer treatment; Controlled release; Crosslinked EVA; Radiation crosslinking

Indexed keywords

CROSSLINKING; DOSIMETRY; ETHYLENE; GAMMA RAYS; IRRADIATION; TENSILE STRENGTH;

5-FLUOROURIDINE; ACETATE FILMS; CONTROLLED RELEASE; CROSSLINKED; CROSSLINKED (ETHYLENE-CO-VINYL ACETATE); ETHYLENE-CO-VINYL ACETATES; GEL CONTENT (%); POLY (ETHYLENE-CO-VINYL ACETATE); POLY[ETHYLENE-CO-(VINYL ACETATE)]; RADIATION CROSS-LINKING;

ELASTIC MODULI;

ANTINEOPLASTIC AGENT; ETHYLENE VINYL ACETATE COPOLYMER; FLOXURIDINE DERIVATIVE; FLUOROURIDINE; OXOBUTYL 5 FLUORO 2' DEOXYURIDINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BIOFILM; BIOMECHANICS; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; CROSS LINKING; DRUG DELIVERY SYSTEM; DRUG IMPLANTATION; DRUG RELEASE; DRUG STRUCTURE; GAMMA RADIATION; GEL; HYPEREMIA; INFLAMMATION; INFRARED RADIATION; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RAT; TENSILE STRENGTH; YOUNG MODULUS;

EID: 33749650351     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2006.05.010     Document Type: Article

References (52)

1. Truter E.J., Santos A.S., and ELS W.J. Assessment of the antitumour activity of targeted immunospecific albumin microspheres loaded with cisplatin and 5-fluorouracil: toxicity against a rodent ovarian carcinoma in vitro. Cell Biol Int 25 1 (2001) 51-59
2. Kurtz J.E., Andrès E., Natarajan-Amé S., Noel E., and Dufour P. Oral chemotherapy in colorectal treatment: review of the literature. Eur J Int Med 14 (2003) 18-25
3. Santi D.V., McHenry C.S., and Sommer H. Mechanism of interaction of thymidylate synthetase with 5-fluorodeoxyuridylate. Biochemistry 13 (1974) 471-481
4. Critchlow C.W., and Kiviat N.B. Old and new issues in cervical cancer control. J Natl Cancer Inst 91 3 (1999) 200-201
5. Monsonego J., Bosch F.X., Coursaget P., Cos J.T., Franco E., and Frazer I. Cervical cancer control, priorities and new directions. Int J Cancer 108 (2004) 329-333
6. Seeff L.C., and McKenna M.T. Cervical cancer mortality among foreign-born women living in the United States, 1985 to 1996. Cancer Detect Prev 27 (2003) 203-208
7. Parkin D.M., Pisani P., and Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 80 (1999) 827-841
8. Van Der Graaf Y., Zirlhius G.A., and Vooijs G.P. Cervical cancer mortality in the Netherlands. Int J Epidemiol 17 (1988) 270-276
9. Bosch F.X. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. J Natl Cancer Inst 87 11 (1995) 796-802
10. Kjaer S.K., van den Brule A.J.C., Paull G., Svare E.I., Sherman M.E., Thomsen B.L., et al. Type specific persistence of high-risk human papillomavirus (HPV) as indicator of high-grade cervical squamous intraepithelial lesions in young women: population based prospective follow up study. Br Med J 325 7364 (2002) 572-575
11. Rozendaal L., Walboomers J.M.M., van der Linden J.C., Voorhorst F.J., Kenemans P., and Helmerhorst T.J. PCR-based high-risk HPV test in cervical cancer screening gives objective risk assessment of women with cytomorphologically normal smears. Int J Cancer 68 (1996) 766-769
12. Woodman C.B.J., Collin S., Winter H., Bailey A., Ellis J., Prior P., et al. Natural history of cervical human papillomavirus infection in young women: a longitudinal study. Lancet 357 (2001) 1831-1836
13. Houghton J.A., Houghton P.J., and Wooten R.S. Mechanism of induction of gastrointestinal toxicity in the mouse by 5-fluorouracil, 5-fluorouridine and 5-fluoro-2′-deoxyuridine. Cancer Res 39 (1979) 2406-2413
14. Schuetz J.D., Wallance H.J., and Diasio R.B. 5-Fluorouracil incorporation into DNA of CF-1 mouse bone marrow cells as a possible mechanism of toxicity. Cancer Res 44 (1984) 1358-1363
15. Kimura Y., and Okuda H. Prevention by carp extract of myelotoxicity and gastrointestinal toxicity induced by 5-fluorouracil without loss of antitumor activity in mice. J Ethnopharm 68 (1999) 39-45
16. Ulbrich K., and Subr V. Polymeric anticancer drugs with pH-controlled activation. Adv Drug Deliv Rev 56 (2004) 1023-1050
17. Huang D.S. Uptake and clearance of 5-fluorouridine following subconjunctival and intravitreal injection. Retina 8 3 (1988) 205-209
18. Koning G.A., Morselt H.W.M., Velinova M.J., et al. Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine (FUdR) from immunoliposomes to colon cancer cells. Biochim Biophys Acta 1420 (1999) 153-167
19. van Laar J.A.M., Rustum Y.M., and Ackland S.P. Comparison of 5-fluoro-2′-deoxyuridine with 5-fluorouracil and their role in the treatment of colorectal cancer. Eur J Cancer 34 (1998) 296-306
20. Bartkowski R., Berger M.R., and Aguiar J.L. Experiments on the efficacy and toxicity of locoregional chemotherapy of liver tumors with 5-fluoro-2′-deoxyuridine (FUDR) and 5-fluorouracil (FU) in an animal model. J Cancer Res Clin Oncol 111 (1986) 42-46
21. Shibamoto Y., Mimasu Y., and Tachi Y. Comparison of 5-fluorouracil and 5-fluoro-2′-deoxyuridine as an effector in radiation-activated prodrug. J Chemother 14 (2002) 390-396
22. Shibamoto Y., Tachi Y., Tanabe K., Hatta H., and Nishimoto S.I. In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2′-deoxyuridine activated by hypoxic irradiation. Int J Radiat Oncol Biol Phys 58 2 (2004) 397-402
23. Steffansen B., Pearson P.A., Buur A., and Ashton P. Alkoxycarbonyl prodrugs of 5-ftuorouracil suspended in silicone oil as an intraocular sustained release system. Pharm Res 9 (1992) S237
24. Baldwin S.P., and Saltzman W.M. Materials for protein delivery in tissue engineering. Adv Drug Deliv Rev 33 (1998) 71-86
25. Lin D.M., Kalachandra S., Valiyaparambil J., and Offenbacher S. A polymeric device for delivery of anti-microbial and antifungal drugs in the oral environment: effect of temperature and medium on the rate of drug release. Dental Mater 19 (2003) 589-596
26. Langer R., and Peppas A.N. Advances in biomaterials, drug delivery and bionanotechnology. AIChE J 49 12 (2003) 2990-3006
27. Sam A.P. Controlled release contraceptive devices: a status report. J Control Release 22 (1992) 35-46
28. Langer R., Brem H., and Tapper D. Biocompatibility of polymeric delivery systems for macromolecules. J Biomed Mater Res 15 (1981) 167-277
29. Niemi S.M., Fox J.G., Brown L.R., and Langer R. Evaluation of ethylene-vinyl acetate copolymer as a non-inflammatory alternative to Freund's complete adjuvant in rabbits. Lab Anim Sci 35 (1985) 609-612
30. Shastri P.V. Toxicology of polymers for implant contraceptives for women. Contraception 65 (2002) 9-13
31. Cho C.W., and Shin S.C. Enhanced transdermal delivery of atenolol from the ethylene-vinyl acetate matrix. Int J Pharm 287 (2004) 67-71
32. Rafferty D.W., and Koenig J.L. FTIR imaging for the characterization of controlled-release drug delivery applications. J Control Release 83 (2002) 29-39
33. Velayudhan S., Anilkumar T.V., Kumary T.V., Mohanan P.V., Fernandez A.C., Varma H.K., et al. Acta Biomater 1 (2005) 201-209
34. Athanasiou K.A., Niederauer G.G., and Agrawal M. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 17 (1996) 93-102
35. Thier R., and Bolt H.M. Carcinogenicity and genotoxicity of ethylene oxide: new aspects and recent advances. Crit Rev Toxicol 30 5 (2000) 595-608
36. Holyoak G.R., Wang S., Liu Y., and Bunch T.D. Toxic effects of ethylene oxide residues on bovine embryos in vitro. Toxicology 108 1-2 (1996) 33-38
37. Benson R.S. Use of radiation in biomaterials science. Nucl Instrum Meth B 191 (2002) 752-757
38. Ishigaki I., and Yoshii F. Radiation effects on polymer materials in radiation sterilization of medical supplies. Radiat Phys Chem 39 6 (1992) 527-533
39. Miyazaki S., Ishi K., Sugibayashi K., Morimoto Y., and Takada M. Antitumor effect of ethylene-vinyl acetate copolymer matrices containing 5-fluorouracil on ehrlich ascites carcinoma in mice. Chem Pharm Bull 30 (1982) 3770-3775
40. Buur A., and Bundgaard H. Prodrugs of 5-fluorouracil V. l-Alkoxycarbonyl derivatives as potential prodrug forms for improved rectal or oral delivery of 5-fluorouracil. J Pharm Sci 75 (1986) 522-527
41. Marchant R., Hiltner A., Hamlin C., Rabinovitch A., Slobodkin R., and Anderson J.M. In vivo biocompatibility studies. The cage implant system and a biodegradable hydrogel. J Biomed Mater Res 17 (1983) 310-325
42. Yamaguchi K., and Anderson J.M. Biocompatibility studies of naltrexone sustained release formulations. J Control Release 19 (1992) 299-314
43. Dutta S.K., Bhowmick A.K., and Chaki T.K. Structure property relationship of ethylene vinyl acetate copolymer grafted with triallyl cyanurate by electron beam radiation. Radiat Phys Chem 47 6 (1996) 913-926
44. Mateev M., and Karageorgiev S. The effect of electron beam irradiation and content of EVA upon the gel-forming processes in LDPE-EVA films. Radiat Phys Chem 51 2 (1998) 205-206
45. Sharif J., Aziz S.H.S.A., and Hashim K. Radiation effects on LDPE/EVA blends. Radiat Phys Chem 58 (2000) 191-195
46. Charlesby A. Atomic radiation and polymers (1960), Pergamon Press, Oxford
47. Socrates G. Infrared characteristic group frequencies (1980), Wiley Interscience, New York, NY
48. Allen N.S., Edge M., Rodriguez M., Liauw C.M., and Fontan E. Aspects of the thermal oxidation, yellowing and stabilisation of ethylene vinyl acetate copolymer. Polym Deg Stab 71 (2001) 1-14
49. Crank J. The mathematics of diffusion. 2nd ed. (1975), Clarendon Press, Oxford
50. Vieth W.R. Diffusion in and through polymers (1991), Hansen, Munich
51. Anderson M., and Shive M.S. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev 28 (1997) 5-24
52. Spilizewski K.L., Marchant R.E., Hamlin C.R., Anderson J.M., Tice T.R., Dappert T.O., et al. The effect of hydrocortisone acetate loaded poly(dl-lactide) films on the inflammatory response. J Control Release 2 (1985) 197-203