Enhanced antisense effect of modified PNAs delivered through functional PMMA microspheres

International Journal of Pharmaceutics

Volumn 324, Issue 1, 2006, Pages 83-91

  Chiarantini, Laura ^a   Cerasi, Aurora ^a   Millo, Enrico ^b   Sparnacci, Katia ^c   Laus, Michele ^c   Riccio, Massimo ^d   Santi, Spartaco ^d   Ballestri, Marco ^d   Spaccasassi, Silvia ^d   Tondelli, Luisa ^d  

^a UNIVERSITY OF URBINO   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^d CNR   (Italy)

Author keywords

Antisense therapy; Ciclooxigenase 2 (COX 2); Core shell microspheres; Macrophages; Peptide nucleic acids (PNA); PMMA microspheres

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; MICROSPHERE; PEPTIDE NUCLEIC ACID; POLY(METHYL METHACRYLATE);

ANIMAL CELL; ARTICLE; DRUG ACTIVITY; DRUG DELIVERY SYSTEM; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ACRYLIC RESINS; ANIMALS; ANTISENSE ELEMENTS (GENETICS); BIOLOGICAL AVAILABILITY; CYCLOOXYGENASE 2; EXCIPIENTS; HYDROGEN-ION CONCENTRATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; PEPTIDE NUCLEIC ACIDS; POLYMETHYL METHACRYLATE; RNA, MESSENGER; THERMODYNAMICS;

EID: 33749647335     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2006.07.007     Document Type: Article

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