A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: Effects in laboratory rat models relating to addiction

Neuropharmacology

Volumn 51, Issue 5, 2006, Pages 993-1003

  Gardner, Eliot L ^a,b   Liu, Xinhe ^b   Paredes, William ^b   Giordano, Anthony ^b,c   Spector, Jordan ^b,d   Lepore, Marino ^b,e   Wu, Kuo Ming ^f,g   Froimowitz, Mark ^f,h  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

^d BOSTON MEDICAL CENTER   (United States)

^e INSTITUTE FOR RESEARCH IN IMMUNOLOGY AND CANCER   (Canada)

^f Pharm Eco   (United States)

^g EISAI RESEARCH INSTITUTE   (United States)

^h MASSACHUSETTS COLLEGE OF PHARMACY AND HEALTH SCIENCES   (United States)

Author keywords

Addiction; Cocaine; Drug abuse; Indanamine; Reuptake blockade

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; COCAINE; COMPOUND 30640; DOPAMINE; DOPAMINE RECEPTOR BLOCKING AGENT; HOMOVANILLIC ACID; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; COCAINE DEPENDENCE; CONTROLLED STUDY; DOPAMINE BRAIN LEVEL; DOPAMINERGIC ACTIVITY; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; DRUG SELF ADMINISTRATION; DRUG SYNTHESIS; MAINTENANCE DRUG DOSE; MAINTENANCE THERAPY; MALE; MICRODIALYSIS; NEUROPHARMACOLOGY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; RAT; REWARD; WAKEFULNESS;

3,4-DIHYDROXYPHENYLACETIC ACID; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; COCAINE; DIALYSIS; DISEASE MODELS, ANIMAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC STIMULATION; HOMOVANILLIC ACID; HYDROXYINDOLEACETIC ACID; INDANS; INDENES; MALE; NEUROTRANSMITTER UPTAKE INHIBITORS; NUCLEUS ACCUMBENS; RATS; RATS, SPRAGUE-DAWLEY; SELF ADMINISTRATION; SUBSTANCE-RELATED DISORDERS; TIME FACTORS;

EID: 33749633480     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.06.009     Document Type: Article

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