메뉴 건너뛰기




Volumn 119, Issue 10, 2006, Pages 2492-2496

The nuclear DNA repair protein Ku70/80 is a tumor-associated antigen displaying rapid receptor mediated endocytosis

Author keywords

Human antibody; Immunotherapy; Internalizing; Ku heterodimer; Phage display

Indexed keywords

CELL NUCLEUS DNA; DOUBLE STRANDED DNA; KU ANTIGEN; RECOMBINANT ANTIBODY; TUMOR ANTIGEN;

EID: 33749590001     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22212     Document Type: Article
Times cited : (10)

References (21)
  • 1
  • 2
    • 0942268167 scopus 로고    scopus 로고
    • Repair of DNA double strand breaks by non-homologous end joining
    • Lees-Miller SP, Meek K. Repair of DNA double strand breaks by non-homologous end joining. Biochimie 2003;85:1161-73.
    • (2003) Biochimie , vol.85 , pp. 1161-1173
    • Lees-Miller, S.P.1    Meek, K.2
  • 3
    • 0025028749 scopus 로고
    • Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen
    • Prabhakar BS, Allaway GP, Srinivasappa J, Notkins AL. Cell surface expression of the 70-kD component of Ku, a DNA-binding nuclear autoantigen. J Clin Invest 1990;86:1301-5.
    • (1990) J Clin Invest , vol.86 , pp. 1301-1305
    • Prabhakar, B.S.1    Allaway, G.P.2    Srinivasappa, J.3    Notkins, A.L.4
  • 4
    • 18944377963 scopus 로고    scopus 로고
    • The double life of the Ku protein: Facing the DNA breaks and the extracellular environment
    • Muller C, Paupert J, Monferran S, Salles B. The double life of the Ku protein: facing the DNA breaks and the extracellular environment. Cell Cycle 2005;4:438-41.
    • (2005) Cell Cycle , vol.4 , pp. 438-441
    • Muller, C.1    Paupert, J.2    Monferran, S.3    Salles, B.4
  • 5
    • 6344261567 scopus 로고    scopus 로고
    • The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9
    • Monferran S, Paupert J, Dauvillier S, Salles B, Muller C. The membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9. EMBO J 2004;23:3758-68.
    • (2004) EMBO J , vol.23 , pp. 3758-3768
    • Monferran, S.1    Paupert, J.2    Dauvillier, S.3    Salles, B.4    Muller, C.5
  • 8
    • 2442508936 scopus 로고    scopus 로고
    • Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics
    • Fransson J, Ek S, Ellmark P, Söderlind E, Borrebaeck CA, Furebring C. Profiling of internalizing tumor-associated antigens on breast and pancreatic cancer cells by reversed genomics. Cancer Lett 2004;208:235-42.
    • (2004) Cancer Lett , vol.208 , pp. 235-242
    • Fransson, J.1    Ek, S.2    Ellmark, P.3    Söderlind, E.4    Borrebaeck, C.A.5    Furebring, C.6
  • 9
    • 0030972407 scopus 로고    scopus 로고
    • Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells
    • Norderhaug L, Olafsen T, Michaelsen TE, Sandlie I. Versatile vectors for transient and stable expression of recombinant antibody molecules in mammalian cells. J Immunol Methods 1997;204:77-87.
    • (1997) J Immunol Methods , vol.204 , pp. 77-87
    • Norderhaug, L.1    Olafsen, T.2    Michaelsen, T.E.3    Sandlie, I.4
  • 10
    • 33745220111 scopus 로고    scopus 로고
    • Rapid induction of apoptosis in B cell lymphoma by functionally isolated human antibodies
    • Fransson J, Tornberg U, Borrebaeck CA, Carlsson R, Frendéus B. Rapid induction of apoptosis in B cell lymphoma by functionally isolated human antibodies. Int J Cancer 2006;119:349-58.
    • (2006) Int J Cancer , vol.119 , pp. 349-358
    • Fransson, J.1    Tornberg, U.2    Borrebaeck, C.A.3    Carlsson, R.4    Frendéus, B.5
  • 11
    • 12344287002 scopus 로고    scopus 로고
    • Modular, scriptable and automated analysis tools for high-throughput peptide mass fingerprinting
    • Samuelsson J, Dalevi D, Levander F, Rognvaldsson T. Modular, scriptable and automated analysis tools for high-throughput peptide mass fingerprinting. Bioinformatics 2004;20;3628-35.
    • (2004) Bioinformatics , vol.20 , pp. 3628-3635
    • Samuelsson, J.1    Dalevi, D.2    Levander, F.3    Rognvaldsson, T.4
  • 12
    • 27644582140 scopus 로고    scopus 로고
    • Measuring the affinity of a radioligand with its receptor using a rotating cell dish with in situ reference area
    • Björke H, Andersson K. Measuring the affinity of a radioligand with its receptor using a rotating cell dish with in situ reference area. Appl Radiat Isot 2006;64:32-7.
    • (2006) Appl Radiat Isot , vol.64 , pp. 32-37
    • Björke, H.1    Andersson, K.2
  • 13
    • 1642556761 scopus 로고    scopus 로고
    • Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells
    • Liu B, Conrad F, Cooperberg MR, Kirpotin DB, Marks ID. Mapping tumor epitope space by direct selection of single-chain Fv antibody libraries on prostate cancer cells. Cancer Res 2004;64:704-10.
    • (2004) Cancer Res , vol.64 , pp. 704-710
    • Liu, B.1    Conrad, F.2    Cooperberg, M.R.3    Kirpotin, D.B.4    Marks, I.D.5
  • 14
    • 27144550160 scopus 로고    scopus 로고
    • Arming antibodies: Prospects and challenges for immunoconjugates
    • Wu AM, Senter PD. Arming antibodies: prospects and challenges for immunoconjugates. Nat Biotechnol 2005;23:1137-46.
    • (2005) Nat Biotechnol , vol.23 , pp. 1137-1146
    • Wu, A.M.1    Senter, P.D.2
  • 15
    • 0036518450 scopus 로고    scopus 로고
    • Receptor-mediated delivery of an antisense gene to human brain cancer cells
    • Zhang Y, Jeong Lee H, Boado RJ, Pardridge WM. Receptor-mediated delivery of an antisense gene to human brain cancer cells. J Gene Med 2002;4:183-94.
    • (2002) J Gene Med , vol.4 , pp. 183-194
    • Zhang, Y.1    Jeong Lee, H.2    Boado, R.J.3    Pardridge, W.M.4
  • 16
    • 1542268960 scopus 로고    scopus 로고
    • The membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin
    • Monferran S, Muller C, Mourey L, Frit P, Salles B. The membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin. J Mol Biol 2004;337:503-11.
    • (2004) J Mol Biol , vol.337 , pp. 503-511
    • Monferran, S.1    Muller, C.2    Mourey, L.3    Frit, P.4    Salles, B.5
  • 17
    • 28944447801 scopus 로고    scopus 로고
    • Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii
    • Martinez JJ, Seveau S, Veiga E, Matsuyama S, Cossart P. Ku70, a component of DNA-dependent protein kinase, is a mammalian receptor for Rickettsia conorii. Cell 2005;123:1013-23.
    • (2005) Cell , vol.123 , pp. 1013-1023
    • Martinez, J.J.1    Seveau, S.2    Veiga, E.3    Matsuyama, S.4    Cossart, P.5
  • 18
    • 27144452013 scopus 로고    scopus 로고
    • In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model
    • Burvenich I, Schoonooghe S, Cornelissen B, Blanckaert P, Coene E, Cuvelier C, Mertens N, Siegers G. In vitro and in vivo targeting properties of iodine-123- or iodine-131-labeled monoclonal antibody 14C5 in a non-small cell lung cancer and colon carcinoma model. Clin Cancer Res 2005;11:7288-96.
    • (2005) Clin Cancer Res , vol.11 , pp. 7288-7296
    • Burvenich, I.1    Schoonooghe, S.2    Cornelissen, B.3    Blanckaert, P.4    Coene, E.5    Cuvelier, C.6    Mertens, N.7    Siegers, G.8
  • 19
    • 27144503834 scopus 로고    scopus 로고
    • Comparative uptakes and biodistributions of internalizing vs. noninternalizing copper-64 radioimmunoconjugates in cell and animal models of colon cancer
    • Bryan JN, Jia F, Mohsin H, Sivaguru G, Miller WH, Anderson CJ, Henry CJ, Lewis MR. Comparative uptakes and biodistributions of internalizing vs. noninternalizing copper-64 radioimmunoconjugates in cell and animal models of colon cancer. Nucl Med Biol 2005;32:851-8.
    • (2005) Nucl Med Biol , vol.32 , pp. 851-858
    • Bryan, J.N.1    Jia, F.2    Mohsin, H.3    Sivaguru, G.4    Miller, W.H.5    Anderson, C.J.6    Henry, C.J.7    Lewis, M.R.8
  • 21
    • 0001577078 scopus 로고
    • Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice
    • Yang HM, Reisfeld RA. Doxorubicin conjugated with a monoclonal antibody directed to a human melanoma-associated proteoglycan suppresses the growth of established tumor xenografts in nude mice. Proc Natl Acad Sci USA 1988;85:1189-93.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1189-1193
    • Yang, H.M.1    Reisfeld, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.