Forced chondrocyte expression of sonic hedgehog impairs joint formation affecting proliferation and apoptosis

Matrix Biology

Volumn 25, Issue 7, 2006, Pages 389-397

  Tavella, S ^b   Biticchi, R ^a   Morello, R ^c   Castagnola, P ^a   Musante, V ^b   Costa, D ^b   Cancedda, R ^a,b   Garofalo, S ^a,b  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Apoptosis; Chondrocytes; Joint formation; Proliferation; Sonic hedgehog; Transgenic mice

Indexed keywords

BIOLOGICAL MARKER; GROWTH DIFFERENTIATION FACTOR 5; PROTEIN; PROTEIN SFRP2; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTHROPATHY; ARTICLE; CARPAL BONE; CARTILAGE CELL; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CHONDROGENESIS; CONTROLLED STUDY; ELBOW; EMBRYO; FEMALE; FUNCTIONAL PROTEOMICS; GROWTH PLATE; HISTOGENESIS; JOINT CAVITY; JOINT DEVELOPMENT; KNEE; METACARPAL BONE; METATARSAL BONE; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PELVIS; PHALANX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHOULDER GIRDLE; SKELETON; TARSAL BONE; TRANSGENIC ANIMAL; WILD TYPE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BONE MORPHOGENETIC PROTEINS; CARTILAGE; CELL PROLIFERATION; CHONDROCYTES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GROWTH DIFFERENTIATION FACTOR 5; HEDGEHOG PROTEINS; JOINTS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; TENASCIN;

ANIMALIA; ERINACEIDAE; MUS MUSCULUS;

EID: 33749432437     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2006.07.005     Document Type: Article

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