Continuous flow augments reactivity of rabbit carotid artery by reducing bioavailability of NO despite an increase in release of EDHF

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 291, Issue 4, 2006, Pages

  Rasmussen, Lasse E ^a   Vanhoutte, Paul M ^a   Jensen, Boye L ^a   Skøtt, Ole ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Conduit arteries; Endothelial shear stress; Endothelium derived hyperpolarizing factor; Nitric oxide; Phenylephrine

Indexed keywords

ACETYLCHOLINE; ALPHA 1 ADRENERGIC RECEPTOR; CYCLIC GMP; MUSCARINIC AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CAROTID ARTERY; CAROTID ARTERY FLOW; CELL FUNCTION; CONTROLLED STUDY; ENDOTHELIUM; NONHUMAN; PRIORITY JOURNAL; RABBIT; SHEAR STRESS;

ACETYLCHOLINE; ANIMALS; BIOLOGICAL FACTORS; CAROTID ARTERIES; CYCLIC GMP; CYCLOOXYGENASE INHIBITORS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; EPOPROSTENOL; INDOMETHACIN; MALE; MUSCLE, SMOOTH, VASCULAR; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; PYRAZOLES; RABBITS; REGIONAL BLOOD FLOW; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 33749331623     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00027.2006     Document Type: Article

References (37)

1. American Veterinary Medical Association Panel on Euthanasia. 2000 report of the AVMA panel on euthanasia. J Am Vet Med Assoc 218: 669-696, 2001.
2. Bauersachs J, Popp R, Hecker M, Sauer E, Fleming I, and Busse R. Nitric oxide attenuates the release of endothelium-derived hyperpolarizing factor. Circulation 94: 3341-3347, 1996.
3. Betik AC, Luckham VB, and Hughson RL. Flow-mediated dilation in human brachial artery after different circulatory occlusion conditions. Am J Physiol Heart Circ Physiol 286: H442-H448, 2004.
4. Bevan JA and Joyce EH. Saline infusion into lumen of resistance artery and small vein causes contraction. Am J Physiol Heart Circ Physiol 259: H23-H28, 1990.
5. Bryan RM Jr, Steenberg ML, and Marrelli SP. Role of endothelium in shear stress-induced constrictions in rat middle cerebral artery. Stroke 32: 1394-1400, 2001.
6. G-nitro-L-arginine methyl ester treatment does not prevent flow-induced remodeling in mesenteric feed arteries and arcading arterioles. Arterioscler Thromb Vasc Biol 20: 2057-2063, 2000.
7. Dube S and Canty JM Jr. Shear stress-induced vasodilation in porcine coronary conduit arteries is independent of nitric oxide release. Am J Physiol Heart Circ Physiol 280: H2581-H2590, 2001.
8. +-channels suppresses EDHF-mediated vasodilation. Br J Pharmacol 138: 594-601, 2003.
9. Feletou M and Vanhoutte PM. EDHF: the Complete Story. Boca Raton, FL: Taylor & Francis, 2006.
10. Feletou M and Vanhoutte PM. EDHF: new therapeutic targets? Pharmacol Res 49: 565-580, 2004.
11. 1D-Adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed. J Pharmacol Exp Ther 296: 869-875, 2001.
12. Ca in endothelium-dependent hyperpolarizations of the guinea-pig isolated carotid artery. Br J Pharmacol 144: 477-485, 2005.
13. Hashimoto M, Miyamoto Y, Matsuda Y, and Akita H. New methods to evaluate endothelial function: non-invasive method of evaluating endothelial function in humans. J Pharmacol Sci 93: 405-408, 2003.
14. Hoeffner U and Vanhoutte PM. Increases in flow reduce the release of endothelium-derived relaxing factor in the aorta of normotensive and spontaneously hypertensive rats. Am J Hypertens 2: 762-767, 1989.
15. Hoogerwerf N, Zijlstra EJ, van der Linden PJ, Westerhof N, and Sipkema P. Endothelium function is protected by albumin and flow-induced constriction is independent of endothelium and tone in isolated rabbit femoral artery. J Vasc Res 29: 367-375, 1992.
16. Katusic ZS, Shepherd JT, and Vanhoutte PM. Endothelium-dependent contraction to stretch in canine basilar arteries. Am J Physiol Heart Circ Physiol 252: H671-H673, 1987.
17. ω-nitro-L- arginine-insensitive endothelium-dependent relaxation of porcine coronary arteries is not mediated by bioassayable relaxing substances. J Cardiovasc Pharmacol 20, Suppl 12: S101-S104, 1992.
18. Komori K, Lorenz RR, and Vanhoutte PM. Nitric oxide, ACh, and electrical and mechanical properties of canine arterial smooth muscle. Am J Physiol Heart Circ Physiol 255: H207-H212, 1988.
19. Luscher TF and Vanhoutte PM. The Endothelium: Modulator of Cardiovascular Function. Boca Raton, FL: CRC, 1990.
20. Majesky MW. Vascular smooth muscle diversity: insights from developmental biology. Curr Atheroscler Rep 5: 208-213, 2003.
21. Martin W, Villani GM, Jothianandan D, and Furchgott RF. Selective blockade of endothelium-dependent and glyceryl trinitrate-induced relaxation by hemoglobin and by methylene blue in the rabbit aorta. J Pharmacol Exp Ther 232: 708-716, 1985.
22. 2+ mobilization to mechanical stretch in endothelial cells. Am J Physiol Cell Physiol 264: C1037-C1044, 1993.
23. Olmos L, Mombouli JV, Illiano S, and Vanhoutte PM. cGMP mediates the desensitization to bradykinin in isolated canine coronary arteries. Am J Physiol Heart Circ Physiol 268: H865-H870, 1995.
24. Peng X, Haldar S, Deshpande S, Irani K, and Kass DA. Wall stiffness suppresses Akt/eNOS and cytoprotection in pulse-perfused endothelium. Hypertension 41: 378-381, 2003.
25. Rasmussen LE and Nedergaard OA. Effects of reboxetine on sympathetic neuroeffector transmission in rabbit carotid artery. J Pharmacol Exp Ther 306: 995-1002, 2003.
26. Rosales OR and Sumpio BE. Changes in cyclic strain increase inositol trisphosphate and diacylglycerol in endothelial cells. Am J Physiol Cell Physiol 262: C956-C962, 1992.
27. Rubanyi GM, Romero JC, and Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol Heart Circ Physiol 250: H1145-H1149, 1986.
28. Shepherd JT and Vanhoutte PM. The Human Cardiovascular System: Facts and Concepts. New York: Raven, 1979.
29. Sho E, Nanjo H, Sho M, Kobayashi M, Komatsu M, Kawamura K, Xu C, Zarins CK, and Masuda H. Arterial enlargement, tortuosity, and intimal thickening in response to sequential exposure to high and low wall shear stress. J Vasc Surg 39: 601-612, 2004.
30. Sho M, Sho E, Singh TM, Komatsu M, Sugita A, Xu C, Nanjo H, Zarins CK, and Masuda H. Subnormal shear stress-induced intimal thickening requires medial smooth muscle cell proliferation and migration. Exp Mol Pathol 72: 150-160, 2002.
31. Sipkema P, van der Linden PJ, Hoogerwerf N, and Westerhof N. Does the endothelium play a role in flow-dependent constriction? A study in the isolated rabbit femoral artery. Blood Vessels 26: 368-376, 1989.
32. Smith WL, DeWitt DL, and Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem 69: 145-182, 2000.
33. Tronc F, Wassef M, Esposito B, Henrion D, Glagov S, and Tedgui A. Role of NO in flow-induced remodeling of the rabbit common carotid artery. Arterioscler Thromb Vasc Biol 16: 1256-1262, 1996.
34. Tzima E, Irani-Tehrani M, Kiosses WB, Dejana E, Schultz DA, Engelhardt B, Cao G, DeLisser H, and Schwartz MA. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 437: 426-431, 2005.
35. Wang Y and Dimitrakopoulos P. Normal force exerted on vascular endothelial cells. Phys Rev Lett 96: 028106, 2006.
36. + channel, IKCa1: a potential immunosuppressant. Proc Natl Acad Sci USA 97: 8151-8156, 2000.
37. Yamawaki H, Lehoux S, and Berk BC. Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo. Circulation 108: 1619-1625, 2003.