α1D-Adrenoceptors cause endothelium-dependent vasodilatation in the rat mesenteric vascular bed

Journal of Pharmacology and Experimental Therapeutics

Volumn 296, Issue 3, 2001, Pages 869-875

  Filippi, Sandra ^a   Parenti, Astrid ^a   Donnini, Sandra ^a   Granger, Harris J ^b   Fazzini, Alessandro ^a   Ledda, Fabrizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 2,5 PYRROLIDINEDIONE; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; ALPHA 1D ADRENERGIC RECEPTOR; CHLOROETHYLCLONIDINE; INDOMETACIN; INOSITOL PHOSPHATE; N(G) NITROARGININE METHYL ESTER; NIGULDIPINE; NITRIC OXIDE SYNTHASE; NORADRENALIN; PHENYLEPHRINE; PRAZOSIN; THAPSIGARGIN;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ALPHA ADRENERGIC STIMULATION; ANIMAL CELL; ARTICLE; CATTLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ANTAGONISM; MESENTERY BLOOD FLOW; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE RELAXATION; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; CATTLE; CELLS, CULTURED; DRUG INTERACTIONS; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; ESTRENES; INOSITOL PHOSPHATES; MESENTERIC ARTERIES; NITRIC OXIDE SYNTHASE; NOREPINEPHRINE; PHENYLEPHRINE; PLATELET AGGREGATION INHIBITORS; PROTEIN ISOFORMS; PYRROLIDINONES; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; SIGNAL TRANSDUCTION; SPLANCHNIC CIRCULATION; THAPSIGARGIN; VASODILATION;

EID: 0035126827     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Thapsigargin inhibits the response to acetylcholine and substance P but does not interfere with the response to endothelium-independent agents
2. Enhancement of the vasoconstrictor response to KCl by nitric oxide inhibition: A comparison with noradrenaline
3. G-nitro-L-arginine
4. Nitric oxide: A ubiquitous messenger
5. Selective inhibition of receptor-coupled phospholipase C-dependent processes in human platelets and polymorphonuclear neutrophils
6. (+)-Niguldipine binds with very high affinity to Ca2+ channels and to a subtype of alpha 1-adrenoceptors
7. Alpha-1-adrenoceptor stimulation induces nitric oxide release in rat pulmonary arteries
8. Mechanism of action of noradrenaline and carbachol on smooth muscle of guinea-pig anterior mesenteric artery
9. Hyperpolarization and increased free calcium in acetylcholine-stimulated endothelial cells
10. Endothelial cell loss enhances the pressor response in resistance vessels
11. α-adrenoceptors in canine mesenteric artery are predominantly 1A subtype: Pharmacological and immunochemical evidence
12. The alpha-adrenoceptor-mediated actions of chloroethylclonidine
13. Regulation of extracellular calcium entry in endothelial cells: Role of intracellular calcium pool
14. Middle T antigen-transformed endothelial cells exhibit an increased activity of nitric oxide synthase
15. BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors
16. The endothelium modulates adrenergic neurotransmission to canine pulmonary arteries and veins
17. β blocker, via multiple mechanisms
18. International Union of Pharmacology. X. Recommendation for nomenclature of alpha 1-adrenoceptors: Consensus update
19. Induction of enhanced release of endothelium-derived relaxing factor after prolonged exposure to alpha-adrenergic agonists: Role of desensitization of smooth muscle contraction
20. U73122 inhibits phospholipase C-dependent calcium mobilization in neuronal cells
21. Involvement of α-adrenoceptors in the endothelium-dependent depression of noradrenaline-induced contraction in rat aorta
22. Differential role of extra-and intracellular calcium in the release of EDRF and prostacyclin from cultured endothelial cells
23. Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps
24. Selective inhibition of agonist-induced but not shear-dependent release of endothelial autacoids by thapsigargin
25. Roles of nitric oxide and endothelium-derived hyperpolarizing factor in vasorelaxant effect of acetylcholine as influenced by aging and hypertension
26. 1-adrenoceptor subtype and two receptor systems in vascular tissues
27. 2+
28. Mechanisms of noradrenaline-induced vasorelaxation in isolated arteries of the neonatal rat
29. Nitric oxide is an upstream signal of vascular endothelial growth factor-induced extracellular signal-regulated kinase 1/2 activation in postcapillary endothelium
30. 1-adrenoceptor subtypes in rabbit aorta and arteries: Regional difference and co-existence
31. Venular endothelial cells from bovine heart
32. 2+-ATPase
33. Endothelial α-adrenergic receptors mediate NO release in arterioles
34. Alpha 2-adrenoceptors and endothelium-derived relaxing factor
35. 1-adrenoceptor subtypes mediating noradrenaline-induced contractions of the rat superior mesenteric artery
36. 2+ oscillations in response to cholecystokinin and carbachol but not to JMV-180 in rat pancreatic acinar cells
37. Alpha1-adrenoceptor subtypes
38. Characterization of subtype of alpha1-adrenoceptor mediating vasoconstriction in perfused rat mesenteric vascular bed
39. Calcium entry, mobilization, and extrusion in postcapillary venular endothelium exposed to bradykinin
40. 1- and α2-adrenoceptor activation