Shear stress-induced vasodilation in porcine coronary conduit arteries is independent of nitric oxide release

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 280, Issue 6 49-6, 2001, Pages

  Dube, Sandeep ^b   Canty Jr , John M ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b NONE

Author keywords

Endothelium dependent hyperpolarizing factor; Endothelium dependent relaxing factor; Pulsatile flow; Steady flow

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; BRADYKININ; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; ENDOTHELIUM DERIVED RELAXING FACTOR; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHLORIDE; TETRYLAMMONIUM CHLORIDE;

ANIMAL TISSUE; ARTERY DIAMETER; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DILATATION; DEPOLARIZATION; ENZYME INHIBITION; FEMALE; HYPERPOLARIZATION; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PULSATILE FLOW; SHEAR STRESS; SWINE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

EID: 0034979142     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.2001.280.6.h2581     Document Type: Article

References (22)

1. Nitric oxide mediates flow-dependent epicardial coronary vasodilation to changes in pulse frequency but not mean flow in conscious dogs
2. Two mechanisms mediate relaxation by bradykinin of pig coronary artery: NO-dependent and -independent responses
3. Methods for isolation, cannulation, and in vitro study of single microvessels
4. Flow-mediated vasodilation of human coronary arterioles does not require nitric oxide synthase
5. Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system
6. cAMP-independent dilation of coronary arterioles to adenosine: Role of nitric oxide, G proteins, and K(ATP) channels
7. Calmidazolium, a calmodulin inhibitor, inhibits endothelium-dependent relaxations resistant to nitro-L-arginine in the canine coronary artery
8. Evidence for differential roles of nitric oxide (NO) and hyperpolarization in endothelium-dependent relaxation of pig isolated coronary artery
9. Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation
10. Interaction of pressure- and flow-induced responses in porcine coronary resistance vessels
11. Myogenic activity in isolated subepicardial and subendocardial coronary arterioles
12. Endothelium-dependent, flow-induced dilation of isolated coronary arterioles
13. Longitudinal gradients for endothelium-dependent and -independent vascular responses in the coronary microcirculation
14. Mechanical deformation of vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed
15. + channels
16. Hyperpolarization as a mechanism for endothelium-dependent relaxation in the porcine coronary artery
17. A transferable, β-naphthoflavone-inducible, hyperpolarizing factor is synthesized by native and cultured porcine coronary endothelial cells
18. Regulation of coronary diameter by myogenic mechanisms in arterial microvessels greater than 100 μm in diameter
19. Pulse pressure-related changes in coronary flow in vivo are modulated by nitric oxide and adenosine
20. Contrasting role of nitric oxide as a mechanism of flow dependent epicardial artery dilation at reduced vs. elevated levels of blood flow in conscious dogs
21. Morphometry of canine coronary arteries, arterioles, and capillaries during hypertension and left ventricular hypertrophy
22. Importance of endothelium-derived nitric oxide in porcine coronary resistance arteries