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Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 39, 2006, Pages 14548-14553

Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity

(6) Chen, Xiaochun a Chong, Curtis R a Shi, Lirong b Yoshimoto, Tadashi c Sullivan Jr , David J b Liu, Jun O a

a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE (United States)

b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH (United States)

c NAGASAKI UNIVERSITY (Japan)

Author keywords

2 (2 pyridinyl) pyrimidine; Drug resistance; High throughput screen

Indexed keywords

2 (2 PYRIDINYL)PYRIMIDINE DERIVATIVE; ANTIMALARIAL AGENT; ARTEMISININ; CHLOROQUINE; ENZYME INHIBITOR; METHIONYL AMINOPEPTIDASE; METHIONYL AMINOPEPTIDASE 1B; NEW DRUG; PYRIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; XC 11;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENTIATION; DRUG SCREENING; DRUG TARGETING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IC 50; MALARIA; MALARIA CONTROL; MOLECULAR CLONING; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PURIFICATION; PROTOZOAL GENETICS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; AMINOPEPTIDASES; ANIMALS; ANTIMALARIALS; CELL PROLIFERATION; DRUG EVALUATION, PRECLINICAL; FIBROBLASTS; GENOME, PROTOZOAN; HUMANS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; PARASITES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; PYRIDINES; PYRIMIDINES; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

PLASMODIUM FALCIPARUM;

EID: 33749245660 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.0604101103 Document Type: Article

Times cited : (97)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.