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Volumn 43, Issue 4, 2006, Pages 251-261

New Drugs for the Treatment of Advanced-Stage Diffuse Large Cell Lymphomas

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; 4 PHENYLBUTYRIC ACID; AMG 623; ANTINEOPLASTIC AGENT; APRIL PROTEIN; BELIMUMAB; BORTEZOMIB; DEPSIPEPTIDE; ENZASTAURIN; EPOTHILONE B; FR 901228; GX 15 070; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN; IPSI 001; ISOSORBIDE; IXABEPILONE; KINESIN SPINDLE PROTEIN INHIBITOR; N (2 AMINOPHENYL) 4 (3 PYRIDINYLMETHOXYCARBONYLAMINOMETHYL)BENZAMIDE; PEPTIDE DERIVATIVE; PR 171; PRALATREXATE; PREMETREXED; PROTEIN BCL 2; PROTEIN BCL 6; TRICHOSTATIN A; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; VORINOSTAT;

EID: 33749244668     PISSN: 00371963     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminhematol.2006.07.002     Document Type: Article
Times cited : (10)

References (68)
  • 1
    • 0027495491 scopus 로고
    • Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma
    • Ye B.H., Lista F., Lo Coco F., et al. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science 262 (1993) 747-750
    • (1993) Science , vol.262 , pp. 747-750
    • Ye, B.H.1    Lista, F.2    Lo Coco, F.3
  • 2
    • 0027299245 scopus 로고
    • Cloning of bcl-6, the locus involved in chromosome translocations affecting band 3q27 in B-cell lymphoma
    • Ye B.H., Rao P.H., Chaganti R.S., et al. Cloning of bcl-6, the locus involved in chromosome translocations affecting band 3q27 in B-cell lymphoma. Cancer Res 53 (1993) 2732-2735
    • (1993) Cancer Res , vol.53 , pp. 2732-2735
    • Ye, B.H.1    Rao, P.H.2    Chaganti, R.S.3
  • 3
    • 0029562068 scopus 로고
    • Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma
    • Ye B.H., Chaganti S., Chang C.C., et al. Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. EMBO J 14 (1995) 6209-62017
    • (1995) EMBO J , vol.14 , pp. 6209-62017
    • Ye, B.H.1    Chaganti, S.2    Chang, C.C.3
  • 4
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent A.L., Shaffer A.L., Yu X., et al. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science 276 (1997) 589-592
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3
  • 5
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer A.L., Yu X., He Y., et al. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity 13 (2000) 199-212
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3
  • 6
    • 1042303640 scopus 로고    scopus 로고
    • Molecular pathogenesis of non-Hodgkin's lymphoma: The role of Bcl-6
    • Pasqualucci L., Bereschenko O., Niu H., et al. Molecular pathogenesis of non-Hodgkin's lymphoma: The role of Bcl-6. Leuk Lymphoma 44 suppl 3 (2003) S5-S12
    • (2003) Leuk Lymphoma , vol.44 , Issue.SUPPL. 3
    • Pasqualucci, L.1    Bereschenko, O.2    Niu, H.3
  • 7
    • 12944255838 scopus 로고    scopus 로고
    • Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia
    • Capello D., Vitolo U., Pasqualucci L., et al. Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia. Blood 95 (2000) 651-659
    • (2000) Blood , vol.95 , pp. 651-659
    • Capello, D.1    Vitolo, U.2    Pasqualucci, L.3
  • 8
    • 0036898253 scopus 로고    scopus 로고
    • Acetylation inactivates the transcriptional repressor BCL6
    • Bereshchenko O.R., Gu W., and Dalla-Favera R. Acetylation inactivates the transcriptional repressor BCL6. Nat Genet 32 (2002) 606-613
    • (2002) Nat Genet , vol.32 , pp. 606-613
    • Bereshchenko, O.R.1    Gu, W.2    Dalla-Favera, R.3
  • 9
    • 0035913911 scopus 로고    scopus 로고
    • Negative control of p53 by Sir2alpha promotes cell survival under stress
    • Luo J., Nikolaev A.Y., Imai S., et al. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107 (2001) 137-148
    • (2001) Cell , vol.107 , pp. 137-148
    • Luo, J.1    Nikolaev, A.Y.2    Imai, S.3
  • 10
    • 0035913903 scopus 로고    scopus 로고
    • hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
    • Vaziri H., Dessain S.K., Ng Eaton E., et al. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107 (2001) 149-159
    • (2001) Cell , vol.107 , pp. 149-159
    • Vaziri, H.1    Dessain, S.K.2    Ng Eaton, E.3
  • 11
    • 0034677535 scopus 로고    scopus 로고
    • Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
    • Imai S., Armstrong C.M., Kaeberlein M., et al. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403 (2000) 795-800
    • (2000) Nature , vol.403 , pp. 795-800
    • Imai, S.1    Armstrong, C.M.2    Kaeberlein, M.3
  • 12
    • 0036906832 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: from target to clinical trials
    • Kelly W.K., O'Connor O.A., and Marks P.A. Histone deacetylase inhibitors: from target to clinical trials. Expert Opin Investig Drugs 11 (2002) 1695-1713
    • (2002) Expert Opin Investig Drugs , vol.11 , pp. 1695-1713
    • Kelly, W.K.1    O'Connor, O.A.2    Marks, P.A.3
  • 13
    • 12444321545 scopus 로고    scopus 로고
    • Phase I clinical trial of histone deacetylase inhibitor: Suberoylanilide hydroxamic acid administered intravenously
    • Kelly W.K., Richon V.M., O'Connor O., et al. Phase I clinical trial of histone deacetylase inhibitor: Suberoylanilide hydroxamic acid administered intravenously. Clin Cancer Res 9 (2003) 3578-3588
    • (2003) Clin Cancer Res , vol.9 , pp. 3578-3588
    • Kelly, W.K.1    Richon, V.M.2    O'Connor, O.3
  • 14
    • 33644836549 scopus 로고    scopus 로고
    • Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies
    • O'Connor O.A., Heaney M.L., Schwartz L., et al. Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies. J Clin Oncol 24 (2006) 166-173
    • (2006) J Clin Oncol , vol.24 , pp. 166-173
    • O'Connor, O.A.1    Heaney, M.L.2    Schwartz, L.3
  • 15
    • 21244464349 scopus 로고    scopus 로고
    • Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer
    • Kelly W.K., O'Connor O.A., Krug L.M., et al. Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. J Clin Oncol 23 (2005) 3923-3931
    • (2005) J Clin Oncol , vol.23 , pp. 3923-3931
    • Kelly, W.K.1    O'Connor, O.A.2    Krug, L.M.3
  • 16
    • 2942535832 scopus 로고    scopus 로고
    • T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance
    • Piekarz R.L., Robey R.W., Zhan Z., et al. T-cell lymphoma as a model for the use of histone deacetylase inhibitors in cancer therapy: impact of depsipeptide on molecular markers, therapeutic targets, and mechanisms of resistance. Blood 103 (2004) 4636-4643
    • (2004) Blood , vol.103 , pp. 4636-4643
    • Piekarz, R.L.1    Robey, R.W.2    Zhan, Z.3
  • 17
    • 0035525781 scopus 로고    scopus 로고
    • Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: A case report
    • Piekarz R.L., Robey R., Sandor V., et al. Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: A case report. Blood 98 (2001) 2865-2868
    • (2001) Blood , vol.98 , pp. 2865-2868
    • Piekarz, R.L.1    Robey, R.2    Sandor, V.3
  • 18
    • 33745893883 scopus 로고    scopus 로고
    • Phase II trial of oral suberoylanilide hydroxamic acid (SAHA) for cutaneous T-cell lymphoma (CTCL) unresponsive to conventional therapy
    • (abstr 6571)
    • Duvic M.T.R., Zhang C., Goy A., Richon V., and Frankel S. Phase II trial of oral suberoylanilide hydroxamic acid (SAHA) for cutaneous T-cell lymphoma (CTCL) unresponsive to conventional therapy. J Clin Oncol 23 (2005) 16S (abstr 6571)
    • (2005) J Clin Oncol , vol.23
    • Duvic, M.T.R.1    Zhang, C.2    Goy, A.3    Richon, V.4    Frankel, S.5
  • 19
    • 21244458052 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma
    • Ryan Q.C., Headlee D., Acharya M., et al. Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma. J Clin Oncol 23 (2005) 3912-3922
    • (2005) J Clin Oncol , vol.23 , pp. 3912-3922
    • Ryan, Q.C.1    Headlee, D.2    Acharya, M.3
  • 21
    • 11144277489 scopus 로고    scopus 로고
    • Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells
    • Polo J.M., Dell'Oso T., Ranuncolo S.M., et al. Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nat Med 10 (2004) 1329-1335
    • (2004) Nat Med , vol.10 , pp. 1329-1335
    • Polo, J.M.1    Dell'Oso, T.2    Ranuncolo, S.M.3
  • 22
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed J.C. Dysregulation of apoptosis in cancer. J Clin Oncol 17 (1999) 2941-2953
    • (1999) J Clin Oncol , vol.17 , pp. 2941-2953
    • Reed, J.C.1
  • 23
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed J.C. Bcl-2 and the regulation of programmed cell death. J Cell Biol 124 (1994) 1-6
    • (1994) J Cell Biol , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 24
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
    • Cleary M.L., Smith S.D., and Sklar J. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell 47 (1986) 19-28
    • (1986) Cell , vol.47 , pp. 19-28
    • Cleary, M.L.1    Smith, S.D.2    Sklar, J.3
  • 25
    • 0022379447 scopus 로고
    • The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining
    • Tsujimoto Y., Gorham J., Cossman J., et al. The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining. Science 229 (1985) 1390-1393
    • (1985) Science , vol.229 , pp. 1390-1393
    • Tsujimoto, Y.1    Gorham, J.2    Cossman, J.3
  • 26
    • 0022546957 scopus 로고
    • Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma
    • Tsujimoto Y., and Croce C.M. Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma. Proc Natl Acad Sci U S A 83 (1986) 5214-5218
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 5214-5218
    • Tsujimoto, Y.1    Croce, C.M.2
  • 27
    • 0031036872 scopus 로고    scopus 로고
    • Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
    • Yang J., Liu X., Bhalla K., et al. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked. Science 275 (1997) 1129-1132
    • (1997) Science , vol.275 , pp. 1129-1132
    • Yang, J.1    Liu, X.2    Bhalla, K.3
  • 28
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck R.M., Bossy-Wetzel E., Green D.R., et al. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 275 (1997) 1132-1136
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3
  • 29
    • 33749258728 scopus 로고    scopus 로고
    • Efficacy and safety of the combination of genasense fludarabine and rituximab in previously treated and untreated subjects with chronic lymphocytic leukemia
    • (abstr 2129)
    • Rai K., Wallace P., Soho C., Landrigan B., Meyn P., Wei T., et al. Efficacy and safety of the combination of genasense fludarabine and rituximab in previously treated and untreated subjects with chronic lymphocytic leukemia. Blood 106 (2005) (abstr 2129)
    • (2005) Blood , vol.106
    • Rai, K.1    Wallace, P.2    Soho, C.3    Landrigan, B.4    Meyn, P.5    Wei, T.6
  • 30
    • 32944475363 scopus 로고    scopus 로고
    • Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia
    • O'Brien S.M., Cunningham C.C., Golenkov A.K., et al. Phase I to II multicenter study of oblimersen sodium, a Bcl-2 antisense oligonucleotide, in patients with advanced chronic lymphocytic leukemia. J Clin Oncol 23 (2005) 7697-7702
    • (2005) J Clin Oncol , vol.23 , pp. 7697-7702
    • O'Brien, S.M.1    Cunningham, C.C.2    Golenkov, A.K.3
  • 31
    • 33646749892 scopus 로고    scopus 로고
    • The combination of the proteasome inhibitor bortezomib and the bcl-2 antisense molecule oblimersen sensitizes human B-cell lymphomas to cyclophosphamide
    • O'Connor O.A., Smith E.A., Toner L.E., et al. The combination of the proteasome inhibitor bortezomib and the bcl-2 antisense molecule oblimersen sensitizes human B-cell lymphomas to cyclophosphamide. Clin Cancer Res 12 (2006) 2902-2911
    • (2006) Clin Cancer Res , vol.12 , pp. 2902-2911
    • O'Connor, O.A.1    Smith, E.A.2    Toner, L.E.3
  • 32
    • 0024394011 scopus 로고
    • An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease
    • Wu D. An overview of the clinical pharmacology and therapeutic potential of gossypol as a male contraceptive agent and in gynaecological disease. Drugs 38 (1989) 333-341
    • (1989) Drugs , vol.38 , pp. 333-341
    • Wu, D.1
  • 33
    • 0021355071 scopus 로고
    • Differential cytotoxic effect of gossypol on human melanoma, colon carcinoma, and other tissue culture cell lines
    • Tuszynski G.P., and Cossu G. Differential cytotoxic effect of gossypol on human melanoma, colon carcinoma, and other tissue culture cell lines. Cancer Res 44 (1984) 768-771
    • (1984) Cancer Res , vol.44 , pp. 768-771
    • Tuszynski, G.P.1    Cossu, G.2
  • 34
    • 0028124332 scopus 로고
    • In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines
    • Coyle T., Levante S., Shetler M., et al. In vitro and in vivo cytotoxicity of gossypol against central nervous system tumor cell lines. J Neurooncol 19 (1994) 25-35
    • (1994) J Neurooncol , vol.19 , pp. 25-35
    • Coyle, T.1    Levante, S.2    Shetler, M.3
  • 35
    • 0029031013 scopus 로고
    • Antiproliferative activity of gossypol and gossypolone on human breast cancer cells
    • Gilbert N.E., O'Reilly J.E., Chang C.J., et al. Antiproliferative activity of gossypol and gossypolone on human breast cancer cells. Life Sci 57 (1995) 61-67
    • (1995) Life Sci , vol.57 , pp. 61-67
    • Gilbert, N.E.1    O'Reilly, J.E.2    Chang, C.J.3
  • 36
    • 0034692871 scopus 로고    scopus 로고
    • Cytotoxic effect of gossypol on colon carcinoma cells
    • Wang X., Wang J., Wong S.C., et al. Cytotoxic effect of gossypol on colon carcinoma cells. Life Sci 67 (2000) 2663-2671
    • (2000) Life Sci , vol.67 , pp. 2663-2671
    • Wang, X.1    Wang, J.2    Wong, S.C.3
  • 37
    • 0027460576 scopus 로고
    • Oral gossypol in the treatment of metastatic adrenal cancer
    • Flack M.R., Pyle R.G., Mullen N.M., et al. Oral gossypol in the treatment of metastatic adrenal cancer. J Clin Endocrinol Metab 76 (1993) 1019-1024
    • (1993) J Clin Endocrinol Metab , vol.76 , pp. 1019-1024
    • Flack, M.R.1    Pyle, R.G.2    Mullen, N.M.3
  • 38
    • 0034922672 scopus 로고    scopus 로고
    • Oral gossypol in the treatment of patients with refractory metastatic breast cancer: A phase I/II clinical trial
    • Van Poznak C., Seidman A.D., Reidenberg M.M., et al. Oral gossypol in the treatment of patients with refractory metastatic breast cancer: A phase I/II clinical trial. Breast Cancer Res Treat 66 (2001) 239-248
    • (2001) Breast Cancer Res Treat , vol.66 , pp. 239-248
    • Van Poznak, C.1    Seidman, A.D.2    Reidenberg, M.M.3
  • 39
    • 0032780442 scopus 로고    scopus 로고
    • Gossypol treatment of recurrent adult malignant gliomas
    • Bushunow P., Reidenberg M.M., Wasenko J., et al. Gossypol treatment of recurrent adult malignant gliomas. J Neurooncol 43 (1999) 79-86
    • (1999) J Neurooncol , vol.43 , pp. 79-86
    • Bushunow, P.1    Reidenberg, M.M.2    Wasenko, J.3
  • 40
    • 0036244595 scopus 로고    scopus 로고
    • The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer
    • Liu S., Kulp S.K., Sugimoto Y., et al. The (-)-enantiomer of gossypol possesses higher anticancer potency than racemic gossypol in human breast cancer. Anticancer Res 22 (2002) 33-38
    • (2002) Anticancer Res , vol.22 , pp. 33-38
    • Liu, S.1    Kulp, S.K.2    Sugimoto, Y.3
  • 41
    • 9344226187 scopus 로고    scopus 로고
    • In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells
    • Oliver C.L., Bauer J.A., Wolter K.G., et al. In vitro effects of the BH3 mimetic, (-)-gossypol, on head and neck squamous cell carcinoma cells. Clin Cancer Res 10 (2004) 7757-7763
    • (2004) Clin Cancer Res , vol.10 , pp. 7757-7763
    • Oliver, C.L.1    Bauer, J.A.2    Wolter, K.G.3
  • 42
    • 33749249370 scopus 로고    scopus 로고
    • Targeting antiapoptotic BcL-2 family members with AT-101 in pre-clinical models of aggressive lymphoma in combination with cyclophosphamide (C) and rituximab (R) produces a marked improvement in therapeutic efficacy
    • (abstr 926)
    • Paoluzzi L., Gonen M., Toner L., Smith E., Yang D., Holmund J., et al. Targeting antiapoptotic BcL-2 family members with AT-101 in pre-clinical models of aggressive lymphoma in combination with cyclophosphamide (C) and rituximab (R) produces a marked improvement in therapeutic efficacy. Blood 106 (2005) (abstr 926)
    • (2005) Blood , vol.106
    • Paoluzzi, L.1    Gonen, M.2    Toner, L.3    Smith, E.4    Yang, D.5    Holmund, J.6
  • 43
    • 20444486559 scopus 로고    scopus 로고
    • An inhibitor of Bcl-2 family proteins induces regression of solid tumours
    • Oltersdorf T., Elmore S.W., Shoemaker A.R., et al. An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435 (2005) 677-681
    • (2005) Nature , vol.435 , pp. 677-681
    • Oltersdorf, T.1    Elmore, S.W.2    Shoemaker, A.R.3
  • 44
    • 31544467109 scopus 로고    scopus 로고
    • Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis
    • Petros A.M., Dinges J., Augeri D.J., et al. Discovery of a potent inhibitor of the antiapoptotic protein Bcl-xL from NMR and parallel synthesis. J Med Chem 49 (2006) 656-663
    • (2006) J Med Chem , vol.49 , pp. 656-663
    • Petros, A.M.1    Dinges, J.2    Augeri, D.J.3
  • 45
    • 0021328814 scopus 로고
    • New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties
    • Sirotnak F.M., DeGraw J.I., Moccio D.M., et al. New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties. Cancer Chemother Pharmacol 12 (1984) 18-25
    • (1984) Cancer Chemother Pharmacol , vol.12 , pp. 18-25
    • Sirotnak, F.M.1    DeGraw, J.I.2    Moccio, D.M.3
  • 46
    • 0037409795 scopus 로고    scopus 로고
    • Activity of a novel anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against human lymphoma is superior to methotrexate and correlates with tumor RFC-1 gene expression
    • Wang E.S., O'Connor O., She Y., et al. Activity of a novel anti-folate (PDX, 10-propargyl 10-deazaaminopterin) against human lymphoma is superior to methotrexate and correlates with tumor RFC-1 gene expression. Leuk Lymphoma 44 (2003) 1027-1035
    • (2003) Leuk Lymphoma , vol.44 , pp. 1027-1035
    • Wang, E.S.1    O'Connor, O.2    She, Y.3
  • 47
    • 0020068096 scopus 로고
    • Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice
    • Sirotnak F.M., DeGraw J.I., Chello P.L., et al. Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice. Cancer Treat Rep 66 (1982) 351-358
    • (1982) Cancer Treat Rep , vol.66 , pp. 351-358
    • Sirotnak, F.M.1    DeGraw, J.I.2    Chello, P.L.3
  • 48
    • 0022353539 scopus 로고
    • Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: Biological significance and implications for improved therapy of human cancer
    • Sirotnak F.M. Obligate genetic expression in tumor cells of a fetal membrane property mediating "folate" transport: Biological significance and implications for improved therapy of human cancer. Cancer Res 45 (1985) 3992-4000
    • (1985) Cancer Res , vol.45 , pp. 3992-4000
    • Sirotnak, F.M.1
  • 49
    • 0030966370 scopus 로고    scopus 로고
    • RFC-1 gene expression regulates folate absorption in mouse small intestine
    • Chiao J.H., Roy K., Tolner B., et al. RFC-1 gene expression regulates folate absorption in mouse small intestine. J Biol Chem 272 (1997) 11165-11170
    • (1997) J Biol Chem , vol.272 , pp. 11165-11170
    • Chiao, J.H.1    Roy, K.2    Tolner, B.3
  • 50
    • 0027304579 scopus 로고
    • Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin
    • DeGraw J.I., Colwell W.T., Piper J.R., et al. Synthesis and antitumor activity of 10-propargyl-10-deazaaminopterin. J Med Chem 36 (1993) 2228-2231
    • (1993) J Med Chem , vol.36 , pp. 2228-2231
    • DeGraw, J.I.1    Colwell, W.T.2    Piper, J.R.3
  • 51
    • 32944462826 scopus 로고    scopus 로고
    • Pralatrexate (10-Propargyl-10-Deazaaminopterin(PRX)), a novel antifolate, effects durable complete remissions (CR) in patients with a diversity of drug resistant T-cell lymphomas with minimal toxicity
    • (abstr 2678)
    • O'Connor O.A., Hamlin P., Neylon E., Moskowitz C., Portlock C., Straus D., et al. Pralatrexate (10-Propargyl-10-Deazaaminopterin(PRX)), a novel antifolate, effects durable complete remissions (CR) in patients with a diversity of drug resistant T-cell lymphomas with minimal toxicity. Blood 106 (2005) (abstr 2678)
    • (2005) Blood , vol.106
    • O'Connor, O.A.1    Hamlin, P.2    Neylon, E.3    Moskowitz, C.4    Portlock, C.5    Straus, D.6
  • 52
    • 0033428703 scopus 로고    scopus 로고
    • Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations
    • Mackay F., Woodcock S.A., Lawton P., et al. Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations. J Exp Med 190 (1999) 1697-1710
    • (1999) J Exp Med , vol.190 , pp. 1697-1710
    • Mackay, F.1    Woodcock, S.A.2    Lawton, P.3
  • 53
    • 0034596831 scopus 로고    scopus 로고
    • Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response
    • Do R.K., Hatada E., Lee H., et al. Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response. J Exp Med 192 (2000) 953-964
    • (2000) J Exp Med , vol.192 , pp. 953-964
    • Do, R.K.1    Hatada, E.2    Lee, H.3
  • 54
    • 12944249540 scopus 로고    scopus 로고
    • Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice
    • Khare S.D., Sarosi I., Xia X.Z., et al. Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice. Proc Natl Acad Sci U S A 97 (2000) 3370-3375
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 3370-3375
    • Khare, S.D.1    Sarosi, I.2    Xia, X.Z.3
  • 55
    • 33644913405 scopus 로고    scopus 로고
    • Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders
    • Novak A.J., Grote D.M., Ziesmer S.C., et al. Elevated serum B-lymphocyte stimulator levels in patients with familial lymphoproliferative disorders. J Clin Oncol 24 (2006) 983-987
    • (2006) J Clin Oncol , vol.24 , pp. 983-987
    • Novak, A.J.1    Grote, D.M.2    Ziesmer, S.C.3
  • 56
    • 33645528201 scopus 로고    scopus 로고
    • B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia
    • Elsawa S.F., Novak A.J., Grote D.M., et al. B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenstrom macroglobulinemia. Blood 107 (2006) 2882-2888
    • (2006) Blood , vol.107 , pp. 2882-2888
    • Elsawa, S.F.1    Novak, A.J.2    Grote, D.M.3
  • 57
    • 33644755600 scopus 로고    scopus 로고
    • An APRIL to remember: Novel TNF ligands as therapeutic targets
    • Dillon S.R., Gross J.A., Ansell S.M., et al. An APRIL to remember: Novel TNF ligands as therapeutic targets. Nat Rev Drug Discov 5 (2006) 235-246
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 235-246
    • Dillon, S.R.1    Gross, J.A.2    Ansell, S.M.3
  • 58
    • 0037165261 scopus 로고    scopus 로고
    • CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
    • Coiffier B., Lepage E., Briere J., et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346 (2002) 235-242
    • (2002) N Engl J Med , vol.346 , pp. 235-242
    • Coiffier, B.1    Lepage, E.2    Briere, J.3
  • 59
    • 23044503407 scopus 로고    scopus 로고
    • Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte
    • Feugier P., Van Hoof A., Sebban C., et al. Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: A study by the Groupe d'Etude des Lymphomes de l'Adulte. J Clin Oncol 23 (2005) 4117-4126
    • (2005) J Clin Oncol , vol.23 , pp. 4117-4126
    • Feugier, P.1    Van Hoof, A.2    Sebban, C.3
  • 60
    • 13644249821 scopus 로고    scopus 로고
    • Rituximab-CHOP versus CHOP with or without maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL)
    • (abstr)
    • Habermann T.W.E., Morrison V.A., Cassileth P.A., Cohn J., Dakhil S., Gascoyne R.D., et al. Rituximab-CHOP versus CHOP with or without maintenance rituximab in patients 60 years of age or older with diffuse large B-cell lymphoma (DLBCL). Blood 104 (2004) 40a (abstr)
    • (2004) Blood , vol.104
    • Habermann, T.W.E.1    Morrison, V.A.2    Cassileth, P.A.3    Cohn, J.4    Dakhil, S.5    Gascoyne, R.D.6
  • 61
    • 33646004738 scopus 로고    scopus 로고
    • CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group
    • Pfreundschuh M., Trumper L., Osterborg A., et al. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol 7 (2006) 379-391
    • (2006) Lancet Oncol , vol.7 , pp. 379-391
    • Pfreundschuh, M.1    Trumper, L.2    Osterborg, A.3
  • 62
    • 23244450351 scopus 로고    scopus 로고
    • Pretreatment with rituximab enhances radiosensitivity of non-Hodgkin's lymphoma cells
    • Skvortsova I., Popper B.A., Skvortsov S., et al. Pretreatment with rituximab enhances radiosensitivity of non-Hodgkin's lymphoma cells. J Radiat Res (Tokyo) 46 (2005) 241-248
    • (2005) J Radiat Res (Tokyo) , vol.46 , pp. 241-248
    • Skvortsova, I.1    Popper, B.A.2    Skvortsov, S.3
  • 63
    • 0032761164 scopus 로고    scopus 로고
    • Phase I/II trial of IDEC-Y2B8 radioimmunotherapy for treatment of relapsed or refractory CD20(+) B-cell non-Hodgkin's lymphoma
    • Witzig T.E., White C.A., Wiseman G.A., et al. Phase I/II trial of IDEC-Y2B8 radioimmunotherapy for treatment of relapsed or refractory CD20(+) B-cell non-Hodgkin's lymphoma. J Clin Oncol 17 (1999) 3793-3803
    • (1999) J Clin Oncol , vol.17 , pp. 3793-3803
    • Witzig, T.E.1    White, C.A.2    Wiseman, G.A.3
  • 64
    • 1142305738 scopus 로고    scopus 로고
    • Patients with transformed low grade lymphoma attain durable responses following out-patient radioimmunotherapy with tositumomab and iodine I 131 tositumomab
    • (abstr 1384)
    • Zelenetz A., Salen M., Vose J., Younes A., and Kaminski M. Patients with transformed low grade lymphoma attain durable responses following out-patient radioimmunotherapy with tositumomab and iodine I 131 tositumomab. Blood 100 (2002) 357 (abstr 1384)
    • (2002) Blood , vol.100 , pp. 357
    • Zelenetz, A.1    Salen, M.2    Vose, J.3    Younes, A.4    Kaminski, M.5
  • 65
    • 20044373371 scopus 로고    scopus 로고
    • Yttrium-90 ibrituomomab tiuxetan (Zevalin) for patients with relapsed/refractory diffuse large b-cell lymphoma not appropriate for autologous stem cell transplantation: results of an open-label phase II trial
    • (abstr)
    • Morschhauser F., Huglo D., and Martinelli G. Yttrium-90 ibrituomomab tiuxetan (Zevalin) for patients with relapsed/refractory diffuse large b-cell lymphoma not appropriate for autologous stem cell transplantation: results of an open-label phase II trial. Blood 104 (2004) 41a (abstr)
    • (2004) Blood , vol.104
    • Morschhauser, F.1    Huglo, D.2    Martinelli, G.3
  • 66
    • 33646577675 scopus 로고    scopus 로고
    • Early safety and efficacy analysis of a phase II study of sequential R-CHOP and yttrium-90 ibritumomab tiuxetan (Zevalin) for elderly high risk patients with untreated DLBCL
    • (abstr 926)
    • Hamlin P., Moskowitz C.H., and Wegner B. Early safety and efficacy analysis of a phase II study of sequential R-CHOP and yttrium-90 ibritumomab tiuxetan (Zevalin) for elderly high risk patients with untreated DLBCL. Blood 106 (2005) (abstr 926)
    • (2005) Blood , vol.106
    • Hamlin, P.1    Moskowitz, C.H.2    Wegner, B.3
  • 67
    • 33748889891 scopus 로고    scopus 로고
    • A phase II study of myeloablative I-131-anti-CD20 (tositumomab) radioimmunotherapy (RIT) and autologous hematopoietic stem cell transplantation (ASCT) for adults ≥ 60 years of age with high-risk, relapsed, or refractory B-cell lymphoma
    • (abstr 487)
    • Gopal A., Rajendran J., Gooley T.A., Pagel J., Fisher D., Petersdorf S., et al. A phase II study of myeloablative I-131-anti-CD20 (tositumomab) radioimmunotherapy (RIT) and autologous hematopoietic stem cell transplantation (ASCT) for adults ≥ 60 years of age with high-risk, relapsed, or refractory B-cell lymphoma. Blood 106 (2005) (abstr 487)
    • (2005) Blood , vol.106
    • Gopal, A.1    Rajendran, J.2    Gooley, T.A.3    Pagel, J.4    Fisher, D.5    Petersdorf, S.6
  • 68
    • 33749236780 scopus 로고    scopus 로고
    • Active combination therapy of bortezomib (Velcade) and ibritumomab tiuxetan (Zevalin) in an in vivo diffuse large B-cell lymphoma model
    • Pervan Milena J.C., Matso D., et al. Active combination therapy of bortezomib (Velcade) and ibritumomab tiuxetan (Zevalin) in an in vivo diffuse large B-cell lymphoma model. Blood (2005)
    • (2005) Blood
    • Pervan Milena, J.C.1    Matso, D.2


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