메뉴 건너뛰기




Volumn 168, Issue 39, 2006, Pages 3299-3303

New molecular markers within the chronic myeloproliferative disorders. II: The JAK2 mutation;Nye molekylære markører ved de kroniske myeloproliferative sygdomme: II. Janus tyrosinkinase 2-mutationen

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; JANUS KINASE 2; PHENYLALANINE; VALINE; BIOLOGICAL MARKER; JAK2 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN TYROSINE KINASE;

EID: 33749239401     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (3)

References (40)
  • 1
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood 1951;6:372-5.
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 2
    • 0141528828 scopus 로고    scopus 로고
    • Chronic myeloid leukaemia - Advances in biology and new approaches to treatment
    • Goldman JM, Melo JV. Chronic myeloid leukaemia - advances in biology and new approaches to treatment. N Engl J Med 2003;349:1451-64.
    • (2003) N Engl J Med , vol.349 , pp. 1451-1464
    • Goldman, J.M.1    Melo, J.V.2
  • 3
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-61.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 4
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-8.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 5
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-97.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 6
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser AS et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-90.
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.S.3
  • 7
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome
    • Steensma DP, Dewald GW, Lasho TL et al. The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both "atypical" myeloproliferative disorders and the myelodysplastic syndrome. Blood 2005;106:1207-9.
    • (2005) Blood , vol.106 , pp. 1207-1209
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3
  • 8
    • 21344467318 scopus 로고    scopus 로고
    • Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders
    • Jones AV, Kreil S, Zoi K et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 2005;106:2162-8.
    • (2005) Blood , vol.106 , pp. 2162-2168
    • Jones, A.V.1    Kreil, S.2    Zoi, K.3
  • 9
    • 20744460045 scopus 로고    scopus 로고
    • Identification of an acquired JAK2 mutation in polycythemia vera
    • Zhao R, Xing S, Li Z et al. Identification of an acquired JAK2 mutation in polycythemia vera. J Biol Chem 2005;280:22788-92.
    • (2005) J Biol Chem , vol.280 , pp. 22788-22792
    • Zhao, R.1    Xing, S.2    Li, Z.3
  • 11
    • 0030862714 scopus 로고    scopus 로고
    • Cytokine receptor signal transduction through Jak tyrosine kinases and Stat transcription factors
    • Silvennoinen O, Saharinen P, Paukka K et al. Cytokine receptor signal transduction through Jak tyrosine kinases and Stat transcription factors. APMIS 1997;105:497-509.
    • (1997) APMIS , vol.105 , pp. 497-509
    • Silvennoinen, O.1    Saharinen, P.2    Paukka, K.3
  • 12
    • 17644417451 scopus 로고    scopus 로고
    • A unifying mutation in chronic myeloproliferative disorders
    • JM Goldman. A unifying mutation in chronic myeloproliferative disorders. N Engl J Med 2005;352:1744-6.
    • (2005) N Engl J Med , vol.352 , pp. 1744-1746
    • Goldman, J.M.1
  • 13
    • 0028933799 scopus 로고
    • Signaling through the hematopoietic cytokine receptors
    • Ihle JN, Witthuhn BA, Quelle FW et al. Signaling through the hematopoietic cytokine receptors. Ann Rev Immunol 1995;13:369-98.
    • (1995) Ann Rev Immunol , vol.13 , pp. 369-398
    • Ihle, J.N.1    Witthuhn, B.A.2    Quelle, F.W.3
  • 14
    • 0033976059 scopus 로고    scopus 로고
    • The Jak-Stat pathway in normal and perturbed hematopoiesis
    • Ward AC, Touw I, Yoshimura A. The Jak-Stat pathway in normal and perturbed hematopoiesis. Blood 2000;95:19-29.
    • (2000) Blood , vol.95 , pp. 19-29
    • Ward, A.C.1    Touw, I.2    Yoshimura, A.3
  • 15
    • 0032076542 scopus 로고    scopus 로고
    • Jak2 is essential for signaling through a variety of cytokine receptors
    • Parganas E, Wang D, Stravopodis D et al. Jak2 is essential for signaling through a variety of cytokine receptors. Cell 1998;93:385-95.
    • (1998) Cell , vol.93 , pp. 385-395
    • Parganas, E.1    Wang, D.2    Stravopodis, D.3
  • 16
    • 0842287505 scopus 로고    scopus 로고
    • JAK2 contributes to the intrinsic capacity of primary hematopoietic cells to respond to stem cell factor
    • Radosevic N, Winterstein D, Keller JR et al. JAK2 contributes to the intrinsic capacity of primary hematopoietic cells to respond to stem cell factor. Experimentel Hematology 2004;32:149-56.
    • (2004) Experimentel Hematology , vol.32 , pp. 149-156
    • Radosevic, N.1    Winterstein, D.2    Keller, J.R.3
  • 17
    • 0016391236 scopus 로고
    • Bone-marrow responses in polycythemia vera
    • Prchal JF, Axelrad AA. Bone-marrow responses in polycythemia vera. N Engl J Med 1974;290:1382.
    • (1974) N Engl J Med , vol.290 , pp. 1382
    • Prchal, J.F.1    Axelrad, A.A.2
  • 18
    • 0028045069 scopus 로고
    • Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: Studies in an improved serum-free medium
    • Correa PN, Eskinazi D, Axelrad AA. Circulating erythroid progenitors in polycythemia vera are hypersensitive to insulin-like growth factor-1 in vitro: studies in an improved serum-free medium. Blood 1994;83:99-112.
    • (1994) Blood , vol.83 , pp. 99-112
    • Correa, P.N.1    Eskinazi, D.2    Axelrad, A.A.3
  • 19
    • 0028261196 scopus 로고
    • Polycythemia vera III: Burst-forming units-erythroid (BFU-E) response to stem cell factor and c-kit receptor expression
    • Dai CH, Krantz SB, Green WF et al. Polycythemia vera III: Burst-forming units-erythroid (BFU-E) response to stem cell factor and c-kit receptor expression. Br J Haematol 1994;86:12-21.
    • (1994) Br J Haematol , vol.86 , pp. 12-21
    • Dai, C.H.1    Krantz, S.B.2    Green, W.F.3
  • 20
    • 0026667283 scopus 로고
    • Polycythemia vera II: Hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor
    • Dai CH, Krantz SB, Dessypris EN et al. Polycythemia vera II: hypersensitivity of bone marrow erythroid, granulocyte-macrophage, and megakaryocyte progenitor cells to interleukin-3 and granulocyte-macrophage colony-stimulating factor. Blood 1992;80:891-9.
    • (1992) Blood , vol.80 , pp. 891-899
    • Dai, C.H.1    Krantz, S.B.2    Dessypris, E.N.3
  • 21
    • 0029166875 scopus 로고
    • Increased basal and induced tyrosine phosphorylation of the insulin-like growth factor -1 receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera
    • Mirza AM, Correa PN, Axelrad AA. Increased basal and induced tyrosine phosphorylation of the insulin-like growth factor -1 receptor beta subunit in circulating mononuclear cells of patients with polycythemia vera. Blood 1995;86:877-82.
    • (1995) Blood , vol.86 , pp. 877-882
    • Mirza, A.M.1    Correa, P.N.2    Axelrad, A.A.3
  • 22
    • 2642609475 scopus 로고    scopus 로고
    • Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera
    • Moliterno AR, Hankins D, Spivak JL. Impaired expression of the thrombopoietin receptor by platelets from patients with polycythemia vera. N Engl J Med 1998;338:572-80.
    • (1998) N Engl J Med , vol.338 , pp. 572-580
    • Moliterno, A.R.1    Hankins, D.2    Spivak, J.L.3
  • 23
    • 0031803213 scopus 로고    scopus 로고
    • Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia
    • Hayakawa F, Towatari M, Iida H et al. Differential constitutive activation between STAT-related proteins and MAP kinase in primary acute myelogenous leukaemia. Br J Haematol 1998;101:521-8.
    • (1998) Br J Haematol , vol.101 , pp. 521-528
    • Hayakawa, F.1    Towatari, M.2    Iida, H.3
  • 24
    • 0032528191 scopus 로고    scopus 로고
    • Expression of signal transducers and activator of transcription proteins in acute myeloid leukaemia blasts
    • Xia Z, Baer MR, Block AW et al. Expression of signal transducers and activator of transcription proteins in acute myeloid leukaemia blasts. Cancer Res 1998;58:3173-80.
    • (1998) Cancer Res , vol.58 , pp. 3173-3180
    • Xia, Z.1    Baer, M.R.2    Block, A.W.3
  • 25
    • 13344279401 scopus 로고    scopus 로고
    • STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients
    • Gouilleaux-Gruart V, Gouilleaux F, Desaint C et al. STAT-related transcription factors are constitutively activated in peripheral blood cells from acute leukemia patients. Blood 1996;87:1692-7.
    • (1996) Blood , vol.87 , pp. 1692-1697
    • Gouilleaux-Gruart, V.1    Gouilleaux, F.2    Desaint, C.3
  • 26
    • 0029863169 scopus 로고    scopus 로고
    • Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl
    • Carlesso N, Frank DA, Griffin JD. Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl. J Exp Med 1996;183:811-20.
    • (1996) J Exp Med , vol.183 , pp. 811-820
    • Carlesso, N.1    Frank, D.A.2    Griffin, J.D.3
  • 27
    • 0000506439 scopus 로고    scopus 로고
    • P210 and P190 (BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
    • Ilaria RL Jr., van Etten RA. P210 and P190 (BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem 1996;271:31704-10.
    • (1996) J Biol Chem , vol.271 , pp. 31704-31710
    • Ilaria Jr., R.L.1    Van Etten, R.A.2
  • 28
    • 10744224146 scopus 로고    scopus 로고
    • Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: Possible relationship with FKBP51 overexpression
    • Komura E, Chagraoui H, Mansat de Mas V et al. Spontaneous STAT5 activation induces growth factor independence in idiopathic myelofibrosis: possible relationship with FKBP51 overexpression. Ex Hematol 2003;31:622-30.
    • (2003) Ex Hematol , vol.31 , pp. 622-630
    • Komura, E.1    Chagraoui, H.2    Mansat De Mas, V.3
  • 29
    • 0034982338 scopus 로고    scopus 로고
    • STAT3 is constitutively active in some patients with Polycythemia rubra vera
    • Roder S, Steimle C, Meinhardt G et al. STAT3 is constitutively active in some patients with Polycythemia rubra vera. Exp Hematol 2001;29:694-702.
    • (2001) Exp Hematol , vol.29 , pp. 694-702
    • Roder, S.1    Steimle, C.2    Meinhardt, G.3
  • 31
    • 0033451992 scopus 로고    scopus 로고
    • Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis
    • Shirogane T, Fukada T, Muller JM et al. Synergistic roles for Pim-1 and c-Myc in STAT3-mediated cell cycle progression and antiapoptosis. Immunity 1999;11:709-19.
    • (1999) Immunity , vol.11 , pp. 709-719
    • Shirogane, T.1    Fukada, T.2    Muller, J.M.3
  • 32
    • 0030292721 scopus 로고    scopus 로고
    • Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: Involvement of STAT3 in anti-apoptosis
    • Fukada T, Hibi M, Yamanaka Y et al. Two signals are necessary for cell proliferation induced by a cytokine receptor gp130: involvement of STAT3 in anti-apoptosis. Immunity 1996;5:449-60.
    • (1996) Immunity , vol.5 , pp. 449-460
    • Fukada, T.1    Hibi, M.2    Yamanaka, Y.3
  • 33
    • 0032984589 scopus 로고    scopus 로고
    • Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells
    • Catlett-Falcone R, Landowski TH, Oshiro MM et al. Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. Immunity 1999;10:105-115.
    • (1999) Immunity , vol.10 , pp. 105-115
    • Catlett-Falcone, R.1    Landowski, T.H.2    Oshiro, M.M.3
  • 34
    • 0032711250 scopus 로고    scopus 로고
    • IL-6 up-regulates mcl-1 in human myeloma cells through JAK/STAT rather than ras/MAP kinase pathway
    • Puthier D, Bataille R, Amiot M. IL-6 up-regulates mcl-1 in human myeloma cells through JAK/STAT rather than ras/MAP kinase pathway. Eur J Immunol 1999;29:3945.
    • (1999) Eur J Immunol , vol.29 , pp. 3945
    • Puthier, D.1    Bataille, R.2    Amiot, M.3
  • 35
    • 0842309105 scopus 로고    scopus 로고
    • Multiple signaling pathways are involved in erythropoietin -independent differentiation of erythroid progenitors in polycythemia vera
    • Ugo V, Marzac C, Theyssandier I et al. Multiple signaling pathways are involved in erythropoietin -independent differentiation of erythroid progenitors in polycythemia vera. Exp Hematol 2004;32:179-87.
    • (2004) Exp Hematol , vol.32 , pp. 179-187
    • Ugo, V.1    Marzac, C.2    Theyssandier, I.3
  • 36
    • 0036191941 scopus 로고    scopus 로고
    • Acquired uniparental disomi of chromosome 9p is a frequent stem cell defect in polycythemia vera
    • Kralovics R, Guan Y, Prchal JT. Acquired uniparental disomi of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 2002;30:229-36.
    • (2002) Exp Hematol , vol.30 , pp. 229-236
    • Kralovics, R.1    Guan, Y.2    Prchal, J.T.3
  • 37
    • 0242493826 scopus 로고    scopus 로고
    • Clonal hematopoiesis in familial polycythemia vera suggest the involvement of multiple mutational events in the early pathogenesis of the disease
    • Kralovics R, Stockton DW, Prchal JT. Clonal hematopoiesis in familial polycythemia vera suggest the involvement of multiple mutational events in the early pathogenesis of the disease. Blood 2002;102:3793-6.
    • (2002) Blood , vol.102 , pp. 3793-3796
    • Kralovics, R.1    Stockton, D.W.2    Prchal, J.T.3
  • 38
    • 25844461158 scopus 로고    scopus 로고
    • The Jak2V617F mutation, PRV-1 overexpression and EEC formation define a similar cohort of MPD patients
    • Goerttler PS, Steimle C, Marz E et al. The Jak2V617F mutation, PRV-1 overexpression and EEC formation define a similar cohort of MPD patients. Blood 2005;106:2862-4.
    • (2005) Blood , vol.106 , pp. 2862-2864
    • Goerttler, P.S.1    Steimle, C.2    Marz, E.3
  • 39
    • 0141746188 scopus 로고    scopus 로고
    • Molecular markers in myeloproliferative disorders: From classification to prognosis?
    • Pahl HP. Molecular markers in myeloproliferative disorders: from classification to prognosis? Hematology 2003;8:199-209.
    • (2003) Hematology , vol.8 , pp. 199-209
    • Pahl, H.P.1
  • 40
    • 33749250215 scopus 로고    scopus 로고
    • A phase II trial of pegylated interferon alpha-2b in polycythemia vera and essentieal thrombocythemia
    • Samuelsson J, Hasselbalch H, Bruserud O et al. A phase II trial of pegylated interferon alpha-2b in polycythemia vera and essentieal thrombocythemia. Blood 2004;104:1518.
    • (2004) Blood , vol.104 , pp. 1518
    • Samuelsson, J.1    Hasselbalch, H.2    Bruserud, O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.