메뉴 건너뛰기




Volumn 24, Issue 9, 2006, Pages 2052-2059

Bioreactor expansion of human adult bone marrow-derived mesenchymal stem cells

Author keywords

Bioreactor; Differentiation; Hematopoietic stem cells; Mesenchymal stem cells

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CELL MARKER; COLLAGEN TYPE 2; ENDOGLIN; HERMES ANTIGEN; INTERLEUKIN 3; INTERLEUKIN 6; OSTEOCALCIN; STEM CELL FACTOR; VIMENTIN;

EID: 33749188522     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2005-0591     Document Type: Article
Times cited : (132)

References (38)
  • 1
    • 0034045086 scopus 로고    scopus 로고
    • Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor
    • Ueda T, Tsuji K, Yoshino H. Expansion of human NOD/SCID-repopulating cells by stem cell factor, Flk2/Flt3 ligand, thrombopoietin, IL-6, and soluble IL-6 receptor. J Clin Invest 2000;105:1013-1021.
    • (2000) J Clin Invest , vol.105 , pp. 1013-1021
    • Ueda, T.1    Tsuji, K.2    Yoshino, H.3
  • 2
    • 0034210222 scopus 로고    scopus 로고
    • Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation
    • Almeida-Porada G, Porada CD, Tran N et al. Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation. Blood 2000;95:3620-3627.
    • (2000) Blood , vol.95 , pp. 3620-3627
    • Almeida-Porada, G.1    Porada, C.D.2    Tran, N.3
  • 3
    • 18444374992 scopus 로고    scopus 로고
    • Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice
    • Noort WA, Kruisselbrink AB, in't Anker PS et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002;30:870-878.
    • (2002) Exp Hematol , vol.30 , pp. 870-878
    • Noort, W.A.1    Kruisselbrink, A.B.2    In't Anker, P.S.3
  • 4
    • 0037562968 scopus 로고    scopus 로고
    • Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice
    • Angelopoulou M, Novelli E, Grove JE et al. Cotransplantation of human mesenchymal stem cells enhances human myelopoiesis and megakaryocytopoiesis in NOD/SCID mice. Exp Hematol 2003;31:413-420.
    • (2003) Exp Hematol , vol.31 , pp. 413-420
    • Angelopoulou, M.1    Novelli, E.2    Grove, J.E.3
  • 5
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koc ON, Gerson SL, Cooper BW et al. Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol 2000;18:307-316.
    • (2000) J Clin Oncol , vol.18 , pp. 307-316
    • Koc, O.N.1    Gerson, S.L.2    Cooper, B.W.3
  • 6
    • 1842483153 scopus 로고    scopus 로고
    • Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation
    • Maitra B, Szekely E, Gjini K et al. Human mesenchymal stem cells support unrelated donor hematopoietic stem cells and suppress T-cell activation. Bone Marrow Transplant 2004;33:597-604.
    • (2004) Bone Marrow Transplant , vol.33 , pp. 597-604
    • Maitra, B.1    Szekely, E.2    Gjini, K.3
  • 7
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363:1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 8
    • 17444379357 scopus 로고    scopus 로고
    • Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation
    • Le Blanc K, Ringden O. Immunobiology of human mesenchymal stem cells and future use in hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2005;11:321-334.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 321-334
    • Le Blanc, K.1    Ringden, O.2
  • 9
    • 33745266607 scopus 로고    scopus 로고
    • Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells
    • Sotiropoulou PA, Perez SA, Salagianni M et al. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. STEM CELLS 2006;24:74-85.
    • (2006) Stem Cells , vol.24 , pp. 74-85
    • Sotiropoulou, P.A.1    Perez, S.A.2    Salagianni, M.3
  • 10
    • 0042668340 scopus 로고    scopus 로고
    • Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion
    • Baksh D, Davies JE, Zandstra PW. Adult human bone marrow-derived mesenchymal progenitor cells are capable of adhesion-independent survival and expansion. Exp Hematol 2003;31:723-732.
    • (2003) Exp Hematol , vol.31 , pp. 723-732
    • Baksh, D.1    Davies, J.E.2    Zandstra, P.W.3
  • 11
    • 27644450590 scopus 로고    scopus 로고
    • Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment
    • Baksh D, Davies JE, Zandstra PW. Soluble factor cross-talk between human bone marrow-derived hematopoietic and mesenchymal cells enhances in vitro CFU-F and CFU-O growth and reveals heterogeneity in the mesenchymal progenitor cell compartment. Blood 2005;106:3012-3019.
    • (2005) Blood , vol.106 , pp. 3012-3019
    • Baksh, D.1    Davies, J.E.2    Zandstra, P.W.3
  • 12
    • 0027366275 scopus 로고
    • Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation
    • Verfaillie CM. Soluble factor(s) produced by human bone marrow stroma increase cytokine-induced proliferation and maturation of primitive hematopoietic progenitors while preventing their terminal differentiation. Blood 1993;82:2045-2053.
    • (1993) Blood , vol.82 , pp. 2045-2053
    • Verfaillie, C.M.1
  • 13
    • 0028037626 scopus 로고
    • Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells
    • Zandstra PW, Eaves CJ, Piret JM. Expansion of hematopoietic progenitor cell populations in stirred suspension bioreactors of normal human bone marrow cells. Biotechnology 1994;12:909-914.
    • (1994) Biotechnology , vol.12 , pp. 909-914
    • Zandstra, P.W.1    Eaves, C.J.2    Piret, J.M.3
  • 14
    • 0035878739 scopus 로고    scopus 로고
    • Metastasis-inducing DNA regulates the expression of the osteopontin gene by binding the transcription factor Tcf-4
    • El Tanani M, Barraclough R, Wilkinson MC et al. Metastasis-inducing DNA regulates the expression of the osteopontin gene by binding the transcription factor Tcf-4. Cancer Res 2001;61:5619-5629.
    • (2001) Cancer Res , vol.61 , pp. 5619-5629
    • El Tanani, M.1    Barraclough, R.2    Wilkinson, M.C.3
  • 15
    • 0036626850 scopus 로고    scopus 로고
    • Rhythmicity of engraftment and altered cell cycle kinetics of cytokine-cultured murine marrow in simulated microgravity compared with static cultures
    • Colvin GA, Lambert JF, Carlson JE et al. Rhythmicity of engraftment and altered cell cycle kinetics of cytokine-cultured murine marrow in simulated microgravity compared with static cultures. In Vitro Cell Dev Biol Anim 2002;38:343-351.
    • (2002) In Vitro Cell Dev Biol Anim , vol.38 , pp. 343-351
    • Colvin, G.A.1    Lambert, J.F.2    Carlson, J.E.3
  • 16
    • 0034889611 scopus 로고    scopus 로고
    • Controlling culture dynamics for the expansion of hematopoietic stem cells
    • Madlambayan GJ, Rogers I, Casper RF et al. Controlling culture dynamics for the expansion of hematopoietic stem cells. J Hematother Stem Cell Res 2001;10:481-492.
    • (2001) J Hematother Stem Cell Res , vol.10 , pp. 481-492
    • Madlambayan, G.J.1    Rogers, I.2    Casper, R.F.3
  • 17
    • 0031553981 scopus 로고    scopus 로고
    • Cellular determinants affecting the rate of cytokine in cultures of human hematopoietic cells
    • Zandstra PW, Petzer AL, Eaves CJ et al. Cellular determinants affecting the rate of cytokine in cultures of human hematopoietic cells. Biotechnology and Bioengineering 1997;54:58-66.
    • (1997) Biotechnology and Bioengineering , vol.54 , pp. 58-66
    • Zandstra, P.W.1    Petzer, A.L.2    Eaves, C.J.3
  • 18
    • 0026316479 scopus 로고
    • In vitro myelopoiesis stimulated by rapid medium exchange and supplementation with hematopoietic growth factors
    • Schwartz RM, Emerson SG, Clarke MF et al. In vitro myelopoiesis stimulated by rapid medium exchange and supplementation with hematopoietic growth factors. Blood 1991;78:3155-3161.
    • (1991) Blood , vol.78 , pp. 3155-3161
    • Schwartz, R.M.1    Emerson, S.G.2    Clarke, M.F.3
  • 19
    • 0026053037 scopus 로고
    • Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures
    • Schwartz RM, Palsson BO, Emerson SG. Rapid medium perfusion rate significantly increases the productivity and longevity of human bone marrow cultures. Proc Natl Acad Sci U S A 1991;88:6760-6764.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6760-6764
    • Schwartz, R.M.1    Palsson, B.O.2    Emerson, S.G.3
  • 20
    • 0032078316 scopus 로고    scopus 로고
    • Characterization of hematopoietic cell expansion, oxygen uptake, and glycolysis in a controlled, stirred-tank bioreactor system
    • Collins PC, Nielsen LK, Patel SD et al. Characterization of hematopoietic cell expansion, oxygen uptake, and glycolysis in a controlled, stirred-tank bioreactor system. Biotechnol Prog 1998;14:466-472.
    • (1998) Biotechnol Prog , vol.14 , pp. 466-472
    • Collins, P.C.1    Nielsen, L.K.2    Patel, S.D.3
  • 21
    • 2342461603 scopus 로고    scopus 로고
    • Hematopoietic stem cells: Clinical requirements and developments in ex-vivo culture
    • Mukhopadhyay A, Madhusudhan T, Kumar R. Hematopoietic stem cells: Clinical requirements and developments in ex-vivo culture. Adv Biochem Eng Biotechnol 2004;86:215-253.
    • (2004) Adv Biochem Eng Biotechnol , vol.86 , pp. 215-253
    • Mukhopadhyay, A.1    Madhusudhan, T.2    Kumar, R.3
  • 22
    • 0027304593 scopus 로고
    • In vivo administration of recombinant methionyl human stem cell factor expands the number of human marrow hematopoietic stem cells
    • Tong J, Gordon MS, Srour EF et al. In vivo administration of recombinant methionyl human stem cell factor expands the number of human marrow hematopoietic stem cells. Blood 1993;82:784-791.
    • (1993) Blood , vol.82 , pp. 784-791
    • Tong, J.1    Gordon, M.S.2    Srour, E.F.3
  • 23
    • 0031001564 scopus 로고    scopus 로고
    • Cytokine manipulation of primitive human hematopoietic cell self-renewal
    • Zandstra PW, Conneally E, Petzer AL et al. Cytokine manipulation of primitive human hematopoietic cell self-renewal. Proc Natl Acad Sci U S A 1997;94:4698-4703.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 4698-4703
    • Zandstra, P.W.1    Conneally, E.2    Petzer, A.L.3
  • 24
    • 0034488186 scopus 로고    scopus 로고
    • Negative influence of IL3 on the expansion of human cord blood in vivo long-term repopulating stem cells
    • Piacibello W, Gammaitoni L, Bruno S et al. Negative influence of IL3 on the expansion of human cord blood in vivo long-term repopulating stem cells. J Hematother Stem Cell Res 2000;9:945-956.
    • (2000) J Hematother Stem Cell Res , vol.9 , pp. 945-956
    • Piacibello, W.1    Gammaitoni, L.2    Bruno, S.3
  • 25
    • 0037338272 scopus 로고    scopus 로고
    • Ex vivo expansion of human adult stem cells capable of primary and secondary hemopoietic reconstitution
    • Gammaitoni L, Bruno S, Sanavio F et al. Ex vivo expansion of human adult stem cells capable of primary and secondary hemopoietic reconstitution. Exp Hematol 2003;31:261-270.
    • (2003) Exp Hematol , vol.31 , pp. 261-270
    • Gammaitoni, L.1    Bruno, S.2    Sanavio, F.3
  • 26
    • 0034932187 scopus 로고    scopus 로고
    • Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions
    • Lapidot T. Mechanism of human stem cell migration and repopulation of NOD/SCID and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions. Ann N Y Acad Sci 2001;938:83-95.
    • (2001) Ann N Y Acad Sci , vol.938 , pp. 83-95
    • Lapidot, T.1
  • 27
    • 0032589101 scopus 로고    scopus 로고
    • Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene
    • Cao X, Wang Q, Ju DW et al. Efficient inducation of local and systemic antitumor immune response by liposome-mediated intratumoral co-transfer of interleukin-2 gene and interleukin-6 gene. J Exp Clin Cancer Res 1999;18:191-200.
    • (1999) J Exp Clin Cancer Res , vol.18 , pp. 191-200
    • Cao, X.1    Wang, Q.2    Ju, D.W.3
  • 28
    • 0034654025 scopus 로고    scopus 로고
    • Autologous transplantation of ex vivo expanded bone marrow cells grown from small aliquots after high-dose chemotherapy for breast cancer
    • Stiff P, Chen B, Franklin W et al. Autologous transplantation of ex vivo expanded bone marrow cells grown from small aliquots after high-dose chemotherapy for breast cancer. Blood 2000;95:2169-2174.
    • (2000) Blood , vol.95 , pp. 2169-2174
    • Stiff, P.1    Chen, B.2    Franklin, W.3
  • 29
    • 0032937050 scopus 로고    scopus 로고
    • Ex-vivo expansion of bone marrow progenitor cells for hematopoietic reconstitution following high-dose chemotherapy for breast cancer
    • Bachier CR, Gokmen E, Teale J et al. Ex-vivo expansion of bone marrow progenitor cells for hematopoietic reconstitution following high-dose chemotherapy for breast cancer. Exp Hematol 1999;27:615-623.
    • (1999) Exp Hematol , vol.27 , pp. 615-623
    • Bachier, C.R.1    Gokmen, E.2    Teale, J.3
  • 30
    • 0035925406 scopus 로고    scopus 로고
    • Cytokine-augmented culture of haematopoietic progenitor cells in a novel three-dimensional cell growth matrix
    • Banu N, Rosenzweig M, Kim H et al. Cytokine-augmented culture of haematopoietic progenitor cells in a novel three-dimensional cell growth matrix. Cytokine 2001;13:349-358.
    • (2001) Cytokine , vol.13 , pp. 349-358
    • Banu, N.1    Rosenzweig, M.2    Kim, H.3
  • 32
    • 0030849526 scopus 로고    scopus 로고
    • A clinically suitable ex vivo expansion culture system for LTC-IC and CFC using stroma-conditioned medium
    • Bhatia R, McGlave PB, Miller JS et al. A clinically suitable ex vivo expansion culture system for LTC-IC and CFC using stroma-conditioned medium. Exp Hematol 1997;25:980-991.
    • (1997) Exp Hematol , vol.25 , pp. 980-991
    • Bhatia, R.1    McGlave, P.B.2    Miller, J.S.3
  • 33
    • 0033016970 scopus 로고    scopus 로고
    • FLT3 ligand inhibits apoptosis and promotes survival of myeloid leukemia cell lines
    • Meyer C, Drexler HG. FLT3 ligand inhibits apoptosis and promotes survival of myeloid leukemia cell lines. Leuk Lymphoma 1999;32:577-581.
    • (1999) Leuk Lymphoma , vol.32 , pp. 577-581
    • Meyer, C.1    Drexler, H.G.2
  • 34
    • 0033526067 scopus 로고    scopus 로고
    • Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
    • Bhatia M, Bonnet D, Wu D et al. Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells. J Exp Med 1999;189:1139-1148.
    • (1999) J Exp Med , vol.189 , pp. 1139-1148
    • Bhatia, M.1    Bonnet, D.2    Wu, D.3
  • 35
    • 0030788152 scopus 로고    scopus 로고
    • Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture
    • Bhatia M, Bonnet D, Kapp U et al. Quantitative analysis reveals expansion of human hematopoietic repopulating cells after short-term ex vivo culture. J Exp Med 1997;186:619-624.
    • (1997) J Exp Med , vol.186 , pp. 619-624
    • Bhatia, M.1    Bonnet, D.2    Kapp, U.3
  • 36
    • 0032532361 scopus 로고    scopus 로고
    • Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice
    • Gothot A, van der Loo JC, Clapp DW et al. Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34(+) cells in non-obese diabetic/severe combined immune-deficient mice. Blood 1998;92:2641-2649.
    • (1998) Blood , vol.92 , pp. 2641-2649
    • Gothot, A.1    Van Der Loo, J.C.2    Clapp, D.W.3
  • 37
    • 0032768790 scopus 로고    scopus 로고
    • Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells
    • Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cel Physio 1999;181:67-73.
    • (1999) J Cel Physio , vol.181 , pp. 67-73
    • Conget, P.A.1    Minguell, J.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.