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Volumn 66, Issue 14, 2006, Pages 1487-1497

Sequential combinations of flavopiridol and docetaxel inhibit prostate tumors, induce apoptosis, and decrease angiogenesis in the Gγ/T-15 transgenic house model of prostate cancer

Author keywords

Angiogenesis; Apoptosis; Metastases; Prostate cancer; Transgenic mice

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; CASPASE 3; CREATINE KINASE; CYCLINE; DOCETAXEL; FLAVOPIRIDOL; LACTATE DEHYDROGENASE; PROTEIN BCL XL; X LINKED INHIBITOR OF APOPTOSIS;

EID: 33749076241     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.20478     Document Type: Article
Times cited : (19)

References (48)
  • 2
    • 15844429706 scopus 로고    scopus 로고
    • Mechanisms of the development of androgen independence in prostate cancer
    • So A, Gleave M, Hurtado-Col A, Nelson C. Mechanisms of the development of androgen independence in prostate cancer. World J Urol 2005;23:1-9.
    • (2005) World J Urol , vol.23 , pp. 1-9
    • So, A.1    Gleave, M.2    Hurtado-Col, A.3    Nelson, C.4
  • 5
    • 0036575440 scopus 로고    scopus 로고
    • Mouse models of prostate carcinogenesis
    • Abate-Shen C, Shen MM. Mouse models of prostate carcinogenesis. Trends Genet 2002;18:S1-S5.
    • (2002) Trends Genet , vol.18
    • Abate-Shen, C.1    Shen, M.M.2
  • 6
    • 18444385085 scopus 로고    scopus 로고
    • Survey of genetically engineered mouse models for prostate cancer: Analyzing the molecular basis of prostate cancer development, progression, and metastasis
    • Kasper S. Survey of genetically engineered mouse models for prostate cancer: Analyzing the molecular basis of prostate cancer development, progression, and metastasis. J Cell Biochem 2005; 94:279-297.
    • (2005) J Cell Biochem , vol.94 , pp. 279-297
    • Kasper, S.1
  • 10
    • 0142106795 scopus 로고    scopus 로고
    • Increased fatty acid synthase expression and activity during progression of prostate cancer in the TRAMP model
    • Pflug BR, Pecher SM, Brink AW, Nelson JB, Foster BA. Increased fatty acid synthase expression and activity during progression of prostate cancer in the TRAMP model. Prostate 2003;57:245-254.
    • (2003) Prostate , vol.57 , pp. 245-254
    • Pflug, B.R.1    Pecher, S.M.2    Brink, A.W.3    Nelson, J.B.4    Foster, B.A.5
  • 11
    • 0035866779 scopus 로고    scopus 로고
    • Angiogenesis and prostate cancer: Identification of a molecular progression switch
    • Huss WJ, Hanrahan CF, Barrios RJ, Simons JW, Greenberg NM. Angiogenesis and prostate cancer: Identification of a molecular progression switch. Cancer Res 2001;61:2736-2743.
    • (2001) Cancer Res , vol.61 , pp. 2736-2743
    • Huss, W.J.1    Hanrahan, C.F.2    Barrios, R.J.3    Simons, J.W.4    Greenberg, N.M.5
  • 14
    • 1942503022 scopus 로고    scopus 로고
    • SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis
    • Huss WJ, Barrios RJ, Greenberg NM. SU5416 selectively impairs angiogenesis to induce prostate cancer-specific apoptosis. Mol Cancer Ther 2003;2:611-616.
    • (2003) Mol Cancer Ther , vol.2 , pp. 611-616
    • Huss, W.J.1    Barrios, R.J.2    Greenberg, N.M.3
  • 15
    • 4544361438 scopus 로고    scopus 로고
    • Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer
    • Huss WJ, Lai L, Barrios RJ, Hirschi KK, Greenberg NM. Retinoic acid slows progression and promotes apoptosis of spontaneous prostate cancer. Prostate 2004;61:142-152.
    • (2004) Prostate , vol.61 , pp. 142-152
    • Huss, W.J.1    Lai, L.2    Barrios, R.J.3    Hirschi, K.K.4    Greenberg, N.M.5
  • 16
    • 2342625403 scopus 로고    scopus 로고
    • Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model
    • Gupta S, Adhami VM, Subbarayan M, MacLennan GT, Lewin JS, Hafeli UO, Fu P, Mukhtar H. Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. Cancer Res 2004; 64:3334-3343.
    • (2004) Cancer Res , vol.64 , pp. 3334-3343
    • Gupta, S.1    Adhami, V.M.2    Subbarayan, M.3    MacLennan, G.T.4    Lewin, J.S.5    Hafeli, U.O.6    Fu, P.7    Mukhtar, H.8
  • 17
    • 0030071527 scopus 로고    scopus 로고
    • Prostate, adrenocortical, and brown adipose tumors in fetal globin/T antigen transgenic mice
    • Perez-Stable C, Altman NH, Brown J, Cray C, Harbison M, Roos BA. Prostate, adrenocortical, and brown adipose tumors in fetal globin/T antigen transgenic mice. Lab Invest 1996;74:363-373.
    • (1996) Lab Invest , vol.74 , pp. 363-373
    • Perez-Stable, C.1    Altman, N.H.2    Brown, J.3    Cray, C.4    Harbison, M.5    Roos, B.A.6
  • 18
    • 0031034504 scopus 로고    scopus 로고
    • Prostate cancer progression, metastasis, and gene expression in transgenic mice
    • Perez-Stable C, Altman NH, Mehta PP, Deftos LJ, Roos BA. Prostate cancer progression, metastasis, and gene expression in transgenic mice. Cancer Res 1997;57:900-906.
    • (1997) Cancer Res , vol.57 , pp. 900-906
    • Perez-Stable, C.1    Altman, N.H.2    Mehta, P.P.3    Deftos, L.J.4    Roos, B.A.5
  • 19
    • 0036277685 scopus 로고    scopus 로고
    • The Gγ/T-15 transgenic mouse model of androgen-independent prostate cancer: Target cells of carcinogenesis and the effect of the vitamin D analog EB 1089
    • Perez-Stable CM, Schwartz GG, Farinas A, Finegold M, Binderup L, Howard GA, Roos BA. The Gγ/T-15 transgenic mouse model of androgen-independent prostate cancer: Target cells of carcinogenesis and the effect of the vitamin D analog EB 1089. Cancer Epi Bio Prev 2002;11:555-563.
    • (2002) Cancer Epi Bio Prev , vol.11 , pp. 555-563
    • Perez-Stable, C.M.1    Schwartz, G.G.2    Farinas, A.3    Finegold, M.4    Binderup, L.5    Howard, G.A.6    Roos, B.A.7
  • 21
    • 0029110526 scopus 로고
    • Docetaxel Taxotere(): A review of preclinical and clinical experience. Part I: Preclinical experience
    • Bissery MC, Nohynek G, Sanderink GJ, Lavelle F. Docetaxel (Taxotere(): A review of preclinical and clinical experience. Part I: Preclinical experience. Anticancer Drugs 1995;6:339-355.
    • (1995) Anticancer Drugs , vol.6 , pp. 339-355
    • Bissery, M.C.1    Nohynek, G.2    Sanderink, G.J.3    Lavelle, F.4
  • 22
    • 0034795142 scopus 로고    scopus 로고
    • Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer
    • Pienta KJ. Preclinical mechanisms of action of docetaxel and docetaxel combinations in prostate cancer. Semin Oncol 2001; 28:3-7.
    • (2001) Semin Oncol , vol.28 , pp. 3-7
    • Pienta, K.J.1
  • 23
    • 0141725730 scopus 로고    scopus 로고
    • Mode of action of docetaxel - A basis for combination with novel anticancer agents
    • Herbst RS, Khuri FR. Mode of action of docetaxel - A basis for combination with novel anticancer agents. Cancer Treat Rev 2003;29:407-415.
    • (2003) Cancer Treat Rev , vol.29 , pp. 407-415
    • Herbst, R.S.1    Khuri, F.R.2
  • 24
    • 0036093681 scopus 로고    scopus 로고
    • Flavopiridol, a novel cyclin-dependent kinase inhibitor, in clinical development
    • Zhai S, Senderowicz AM, Sausville EA, Figg WD. Flavopiridol, a novel cyclin-dependent kinase inhibitor, in clinical development. Ann Pharmacother 2002;36:905-911.
    • (2002) Ann Pharmacother , vol.36 , pp. 905-911
    • Zhai, S.1    Senderowicz, A.M.2    Sausville, E.A.3    Figg, W.D.4
  • 25
    • 3042536038 scopus 로고    scopus 로고
    • Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol
    • Shapiro GI. Preclinical and clinical development of the cyclin-dependent kinase inhibitor flavopiridol. Clin Cancer Res 2004; 10:4270s-4275s.
    • (2004) Clin Cancer Res , vol.10
    • Shapiro, G.I.1
  • 28
    • 0348075994 scopus 로고    scopus 로고
    • Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells
    • Motwani M, Rizzo C, Sirotnak F, She Y, Schwartz GK. Flavopiridol enhances the effect of docetaxel in vitro and in vivo in human gastric cancer cells. Mol Cancer Ther 2003;2:549-555.
    • (2003) Mol Cancer Ther , vol.2 , pp. 549-555
    • Motwani, M.1    Rizzo, C.2    Sirotnak, F.3    She, Y.4    Schwartz, G.K.5
  • 29
    • 33745083046 scopus 로고    scopus 로고
    • Sequential combination of flavopiridol and docetaxel reduces the levels of XIAP and AKT proteins and stimulates apoptosis in human LNCaP prostate cancer cells
    • Gomez A, de las Pozas A, Perez-Stable C. Sequential combination of flavopiridol and docetaxel reduces the levels of XIAP and AKT proteins and stimulates apoptosis in human LNCaP prostate cancer cells. Mol Cancer Therapeutics 2006;5:1216-1226.
    • (2006) Mol Cancer Therapeutics , vol.5 , pp. 1216-1226
    • Gomez, A.1    De Las Pozas, A.2    Perez-Stable, C.3
  • 30
    • 0036615319 scopus 로고    scopus 로고
    • Docetaxel in the integrated mangement of prostate cancer. Current applications and future promise
    • Huntingt.
    • Logothetis CJ. Docetaxel in the integrated mangement of prostate cancer. Current applications and future promise. Oncology (Huntingt.) 2002;16:63-72.
    • (2002) Oncology , vol.16 , pp. 63-72
    • Logothetis, C.J.1
  • 31
    • 0346880501 scopus 로고    scopus 로고
    • The inhibitors of apoptosis: There is more to life than Bcl2
    • Liston P, Fong WG, Korneluk RG. The inhibitors of apoptosis: There is more to life than Bcl2. Oncogene 2003;22:8568-8580.
    • (2003) Oncogene , vol.22 , pp. 8568-8580
    • Liston, P.1    Fong, W.G.2    Korneluk, R.G.3
  • 32
    • 5644259587 scopus 로고    scopus 로고
    • Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice
    • Schimmer AD. Inhibitor of apoptosis proteins: Translating basic knowledge into clinical practice. Cancer Res 2004;64:7183-7190.
    • (2004) Cancer Res , vol.64 , pp. 7183-7190
    • Schimmer, A.D.1
  • 34
    • 0032804733 scopus 로고    scopus 로고
    • Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells
    • Motwani M, Delohery TM, Schwartz GK. Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells. Clin Cancer Res 1999;5:1876-1883.
    • (1999) Clin Cancer Res , vol.5 , pp. 1876-1883
    • Motwani, M.1    Delohery, T.M.2    Schwartz, G.K.3
  • 36
    • 0031028190 scopus 로고    scopus 로고
    • Immortalized and tumorigenic adult human prostatic epithelial cell lines: Characteristics and applications. Part 3. Oncogenes, suppressor genes, and applications
    • Webber MM, Bello D, Quader S. Immortalized and tumorigenic adult human prostatic epithelial cell lines: Characteristics and applications. Part 3. Oncogenes, suppressor genes, and applications. Prostate 1997;30:136-142.
    • (1997) Prostate , vol.30 , pp. 136-142
    • Webber, M.M.1    Bello, D.2    Quader, S.3
  • 37
    • 0033942505 scopus 로고    scopus 로고
    • Apoptosis in prostate carcinogenesis. A growth regulator and a therapeutic target
    • Bruckheimer EM, Kyprianou N. Apoptosis in prostate carcinogenesis. A growth regulator and a therapeutic target. Cell Tissue Res 2000;301:153-162.
    • (2000) Cell Tissue Res , vol.301 , pp. 153-162
    • Bruckheimer, E.M.1    Kyprianou, N.2
  • 43
    • 4444280830 scopus 로고    scopus 로고
    • X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells
    • Amantana A, London CA, Iversen PL, Devi GR. X-linked inhibitor of apoptosis protein inhibition induces apoptosis and enhances chemotherapy sensitivity in human prostate cancer cells. Mol Cancer Ther 2004;3:699-707.
    • (2004) Mol Cancer Ther , vol.3 , pp. 699-707
    • Amantana, A.1    London, C.A.2    Iversen, P.L.3    Devi, G.R.4
  • 45
    • 20344367537 scopus 로고    scopus 로고
    • Tumour vascular targeting
    • Neri D, Bicknell R. Tumour vascular targeting. Nat Rev Cancer 2005;5:436-446.
    • (2005) Nat Rev Cancer , vol.5 , pp. 436-446
    • Neri, D.1    Bicknell, R.2
  • 46
    • 0036101635 scopus 로고    scopus 로고
    • Flavopiridol inhibits vascular endothelial growth factor production induced by hypoxia or picolinic acid in human neuroblastoma
    • Rapella A, Negrioli A, Melillo G, Pastorino S, Varesio L, Bosco MC. Flavopiridol inhibits vascular endothelial growth factor production induced by hypoxia or picolinic acid in human neuroblastoma. Int J Cancer 2002;99:658-664.
    • (2002) Int J Cancer , vol.99 , pp. 658-664
    • Rapella, A.1    Negrioli, A.2    Melillo, G.3    Pastorino, S.4    Varesio, L.5    Bosco, M.C.6
  • 47
    • 0035870297 scopus 로고    scopus 로고
    • The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors
    • Sweeney CJ, Miller KD, Sissons SE, Nozaki S, Heilman DK, Shen J, Sledge GW Jr. The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factors. Cancer Res 2001;61:3369-3372.
    • (2001) Cancer Res , vol.61 , pp. 3369-3372
    • Sweeney, C.J.1    Miller, K.D.2    Sissons, S.E.3    Nozaki, S.4    Heilman, D.K.5    Shen, J.6    Sledge Jr., G.W.7
  • 48
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.