Heterotrimer formation, together with isoprenylation, is required for plasma membrane targeting of Gβγ

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 17284-17290

  Takida, Satoshi ^b   Wedegaertner, Philip B ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; MUTAGENESIS; PROTEINS;

PLASMA MEMBRANES (PM);

CELL MEMBRANES;

GUANINE NUCLEOTIDE BINDING PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN SUBUNIT;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL FRACTIONATION; CELL MEMBRANE; CONFOCAL MICROSCOPY; CYTOPLASM; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE MICROSCOPY; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL STRAIN COS1; CHEMISTRY; DIMERIZATION; METABOLISM; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

ANIMALIA;

ANIMALS; COS CELLS; DIMERIZATION; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; PROTEIN BINDING; PROTEIN ISOPRENYLATION; PROTEIN SUBUNITS; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

EID: 0038607927     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213239200     Document Type: Article

References (33)

1. Dunphy, J. T., and Linder, M. E. (1998) Biochim. Biophys. Acta 1436, 245-261
2. Wedegaertner, P. B. (1998) Biol. Signals Recept. 7, 125-135
3. Chen, C. A., and Manning, D. R. (2001) Oncogene 20, 1643-1652
4. Gelb, M. H., Scholten, J. D., and Sebolt-Leopold, J. S. (1998) Curr. Opin. Chem. Biol. 2, 40-48
5. Fu, H. W., and Casey, P. J. (1999) Recent Prog. Horm. Res. 54, 315-343
6. Hancock, J. F., Paterson, H., and Marshall, C. J. (1990) Cell 63, 133-139
7. Hancock, J. F., Cadwallader, K., Paterson, H., and Marshall, C. J. (1991) EMBO J. 10, 4033-4039
8. Hirschman, J. E., and Jenness, D. D. (1999) Mol. Cell. Biol. 19, 7705-7711
9. Evanko, D. S., Thiyagarajan, M. M., Siderovski, D. P., and Wedegaertner, P. B. (2001) J. Biol. Chem. 276, 23945-23953
10. Evanko, D. S., Thiyagarajan, M. M., and Wedegaertner, P. B. (2000) J. Biol. Chem. 275, 1327-1336
11. Fishburn, C. S., Pollitt, S. K., and Bourne, H. R. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 1085-1090
12. Li, Y., Sternweis, P. M., Charnecki, S., Smith, T. F., Gilman, A. G., Neer, E. J., and Kozasa, T. (1998) J. Biol. Chem. 273, 16265-16272
13. Michaelson, D., Ahearn, I., Bergo, M., Young, S., and Philips, M. (2002) Mol. Biol. Cell 13, 3294-3302
14. Higgins, J. B., and Casey, P. J. (1996) Cell. Signal. 8, 433-437
15. Manahan, C. L., Patnana, M., Blumer, K. J., and Linder, M. E. (2000) Mol. Biol. Cell 11, 957-968
16. Shore, G. C., McBride, H. M., Millar, D. G., Steenaart, N. A., and Nguyen, M. (1995) Eur. J. Biochem. 227, 9-18
17. Wall, M. A., Coleman, D. E., Lee, E., Iniguez-Lluhi, J. A., Posner, B. A., Gilman, A. G., and Sprang, S. R. (1995) Cell 83, 1047-1058
18. Lambright, D. G., Sondek, J., Bohm, A., Skiba, N. P., Hamm, H. E., and Sigler, P. B. (1996) Nature 379, 311-319
19. Ford, C. E., Skiba, N. P., Bae, H., Daaka, Y., Reuveny, E., Shekter, L. R., Rosal, R., Weng, G., Yang, C. S., Iyengar, R., Miller, R. J., Jan, L. Y., Lefkowitz, R. J., and Hamm, H. E. (1998) Science 280, 1271-1274
20. Muntz, K. H., Sternweis, P. C., Gilman, A. G., and Mumby, S. M. (1992) Mol. Biol. Cell 3, 49-61
21. Iniguez-Lluhi, J. A., Simon, M. I., Robishaw, J. D., and Gilman, A. G. (1992) J. Biol. Chem. 267, 23409-23417
22. Song, J., Hirschman, J., Gunn, K., and Dohlman, H. G. (1996) J. Biol. Chem. 271, 20273-20283
23. Gotta, M., and Ahringer, J. (2001) Nat. Cell Biol. 3, 297-300
24. Choy, E., Chiu, V. K., Silletti, J., Feoktistov, M., Morimoto, T., Michaelson, D., Ivanov, I. E., and Philips, M. R. (1999) Cell 98, 69-80
25. Apolloni, A., Prior, I. A., Lindsay, M., Parton, R. G., and Hancock, J. F. (2000) Mol. Cell. Biol. 20, 2475-2487
26. Schmidt, W. K., Tam, A., Fujimura-Kamada, K., and Michaelis, S. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 11175-11180
27. Dai, Q., Choy, E., Chiu, V., Romano, J., Slivka, S. R., Steitz, S. A., Michaelis, S., and Philips, M. R. (1998) J. Biol. Chem. 273, 15030-15034
28. Degtyarev, M. Y., Spiegel, A. M., and Jones, T. L. (1994) J. Biol. Chem. 269, 30898-30903
29. Morales, J., Fishburn, C. S., Wilson, P. T., and Bourne, H. R. (1998) Mol. Biol. Cell 9, 1-14
30. Fishburn, C. S., Herzmark, P., Morales, J., and Bourne, H. R. (1999) J. Biol. Chem. 274, 18793-18800
31. Denker, S. P., McCaffery, J. M., Palade, G. E., Insel, P. A., and Farquhar, M. G. (1996) J. Cell Biol. 133, 1027-1040
32. Zhao, L., Lobo, S., Dong, X., Ault, A. D., and Deschenes, R. J. (2002) J. Biol. Chem. 277, 49352-49359
33. Lobo, S., Greentree, W. K., Linder, M. E., and Deschenes, R. J. (2002) J. Biol. Chem. 277, 41268-41273