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Volumn 3, Issue 2, 2006, Pages 60-68

An apical GAGA loop within 5′ UTR of the coxsackievirus B3 RNA maintains structural organization of the IRES element required for efficient ribosome entry

Author keywords

5 untranslated region; Cis acting RNA; Coxsackievirus B3; Internal initiation of translation; IRES element; La autoantigen; Picornavirus; Ribosome assembly

Indexed keywords

CIS ACTING ELEMENT; LA ANTIGEN; SMALL INTERFERING RNA; VIRUS RNA;

EID: 33748942064     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.3.2.2990     Document Type: Article
Times cited : (18)

References (47)
  • 2
    • 0000327130 scopus 로고    scopus 로고
    • Picornaviridae: The viruses and their replication
    • Fields BN, Knipe DM, Howley PM, eds. Philadelphia: Lippincott-Raven
    • Rueckert RR. Picornaviridae: The viruses and their replication. In: Fields BN, Knipe DM, Howley PM, eds. Virology. 3rd ed. Philadelphia: Lippincott-Raven, 1996:609-54.
    • (1996) Virology. 3rd Ed. , pp. 609-654
    • Rueckert, R.R.1
  • 3
    • 0029437960 scopus 로고
    • Internal initiation of translation in eukaryotes: The picornavirus paradigm and beyond
    • Jackson RJ, Kaminski A. Internal initiation of translation in eukaryotes: The picornavirus paradigm and beyond. RNA 1995; 1:985-1000.
    • (1995) RNA , vol.1 , pp. 985-1000
    • Jackson, R.J.1    Kaminski, A.2
  • 4
    • 0031550560 scopus 로고    scopus 로고
    • In vitro mutational and inhibitory analysis of the cis-acting translational elements within the 5′untranslated region of Coxsackievirus B3: Potential targets for antiviral action of antisense oligomers
    • Yang D, Wilson JE, Anderson DR, Bohunek L, Cordeiro C, Kandolf R, Mcmanus BM. In vitro mutational and inhibitory analysis of the cis-acting translational elements within the 5′untranslated region of Coxsackievirus B3: Potential targets for antiviral action of antisense oligomers. Virology 1997; 228:63-73.
    • (1997) Virology , vol.228 , pp. 63-73
    • Yang, D.1    Wilson, J.E.2    Anderson, D.R.3    Bohunek, L.4    Cordeiro, C.5    Kandolf, R.6    Mcmanus, B.M.7
  • 5
    • 12844272864 scopus 로고    scopus 로고
    • Mapping of secondary structure of the spacer region within the 5′-untranslated region of the Coxsackievirus B3 RNA: Possible role of an apical GAGA loop in binding la protein and influencing internal initiation of translation
    • Bhattacharyya S, Das S. Mapping of secondary structure of the spacer region within the 5′-untranslated region of the Coxsackievirus B3 RNA: Possible role of an apical GAGA loop in binding La protein and influencing internal initiation of translation. Virus Res 2005; 108:89-100.
    • (2005) Virus Res , vol.108 , pp. 89-100
    • Bhattacharyya, S.1    Das, S.2
  • 6
    • 0033590197 scopus 로고    scopus 로고
    • Structural and functional analysis of the 5′ untranslated region of coxsackievirus B3 RNA: In vivo translational and infectivity studies of full-length mutants
    • Liu Z, Carthy CM, Cheung P, Bohunek L, Wilson JE, McManus BM, Yang D. Structural and functional analysis of the 5′ untranslated region of coxsackievirus B3 RNA: In vivo translational and infectivity studies of full-length mutants. Virology 1999; 265:206-17.
    • (1999) Virology , vol.265 , pp. 206-217
    • Liu, Z.1    Carthy, C.M.2    Cheung, P.3    Bohunek, L.4    Wilson, J.E.5    McManus, B.M.6    Yang, D.7
  • 7
    • 0028024551 scopus 로고
    • Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis
    • Hellen CU, Pestova TV, Wimmer E. Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis. J Virol 1994; 68:6312-22.
    • (1994) J Virol , vol.68 , pp. 6312-6322
    • Hellen, C.U.1    Pestova, T.V.2    Wimmer, E.3
  • 8
    • 26244463200 scopus 로고    scopus 로고
    • Sequence analysis of the 5′ untranslated region of swine vesicular disease virus reveals block deletions between the end of the internal ribosome entry site and the initiation codon
    • Shaw AE, Reid SM, Knowles NJ, Hutchings GH, Wilsden G, Brocchi E, Paton D, King DP. Sequence analysis of the 5′ untranslated region of swine vesicular disease virus reveals block deletions between the end of the internal ribosome entry site and the initiation codon. J Gen Virol 2005; 86:2753-61.
    • (2005) J Gen Virol , vol.86 , pp. 2753-2761
    • Shaw, A.E.1    Reid, S.M.2    Knowles, N.J.3    Hutchings, G.H.4    Wilsden, G.5    Brocchi, E.6    Paton, D.7    King, D.P.8
  • 10
    • 0025061676 scopus 로고
    • Tetraloops and RNA folding
    • Uhlenbeck OC. Tetraloops and RNA folding. Nature 1990; 346:613-4.
    • (1990) Nature , vol.346 , pp. 613-614
    • Uhlenbeck, O.C.1
  • 11
    • 10744229009 scopus 로고    scopus 로고
    • Structural organization of a viral IRES depends on the integrity of the GNRA motif
    • Fernandez-Miragall O, Martinez-Salas E. Structural organization of a viral IRES depends on the integrity of the GNRA motif. RNA 2003; 9:1333-44.
    • (2003) RNA , vol.9 , pp. 1333-1344
    • Fernandez-Miragall, O.1    Martinez-Salas, E.2
  • 12
    • 0025678737 scopus 로고
    • Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis
    • Michel F, Westhof E. Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis. J Mol Biol 1990; 216:585-610.
    • (1990) J Mol Biol , vol.216 , pp. 585-610
    • Michel, F.1    Westhof, E.2
  • 13
    • 0027173193 scopus 로고
    • An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme
    • Murphy FL, Cech TR. An independently folding domain of RNA tertiary structure within the Tetrahymena ribozyme. Biochemistry 1993; 32:5291-300.
    • (1993) Biochemistry , vol.32 , pp. 5291-5300
    • Murphy, F.L.1    Cech, T.R.2
  • 14
    • 0028294458 scopus 로고
    • Involvement of a GNRA tetraloop in long-range RNA tertiary interactions
    • Jaeger L, Michel F, Westhof E. Involvement of a GNRA tetraloop in long-range RNA tertiary interactions. J Mol Biol 1994; 236:1271-6.
    • (1994) J Mol Biol , vol.236 , pp. 1271-1276
    • Jaeger, L.1    Michel, F.2    Westhof, E.3
  • 15
    • 0028037302 scopus 로고
    • Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetra-loop and an RNA helix
    • Pley HM, Flaherty KM, Mckay DB. Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetra-loop and an RNA helix. Nature 1994; 372:111-3.
    • (1994) Nature , vol.372 , pp. 111-113
    • Pley, H.M.1    Flaherty, K.M.2    Mckay, D.B.3
  • 16
    • 0026704534 scopus 로고
    • Ribosomal RNA identity elements for ricin A-chain recognition and catalysis analysis with tetraloop mutants
    • Gluck A, Endo Y, Lin A, Wool IG. Ribosomal RNA identity elements for ricin A-chain recognition and catalysis analysis with tetraloop mutants. J Mol Biol 1992; 226:411-24.
    • (1992) J Mol Biol , vol.226 , pp. 411-424
    • Gluck, A.1    Endo, Y.2    Lin, A.3    Wool, I.G.4
  • 18
    • 0031588542 scopus 로고    scopus 로고
    • Remarkable morphological variability of a common RNA folding motif; the GNRA tetraloop-receptor interaction
    • Abramovitz DL, Pyle AM. Remarkable morphological variability of a common RNA folding motif; the GNRA tetraloop-receptor interaction. J Mol Biol 1997; 266:493-506.
    • (1997) J Mol Biol , vol.266 , pp. 493-506
    • Abramovitz, D.L.1    Pyle, A.M.2
  • 19
    • 0036838729 scopus 로고    scopus 로고
    • Poliovirus internal ribosome entry segment structure alterations that specifically affect function in neuronal cells: Molecular genetic analysis
    • Malnou CE, Poyry TAA, Jackson RJ, Kean KM. Poliovirus internal ribosome entry segment structure alterations that specifically affect function in neuronal cells: Molecular genetic analysis. J Virol 2002; 76:10617-26.
    • (2002) J Virol , vol.76 , pp. 10617-10626
    • Malnou, C.E.1    Poyry, T.A.A.2    Jackson, R.J.3    Kean, K.M.4
  • 20
    • 0030999946 scopus 로고    scopus 로고
    • Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation
    • Lopez de Quinto S, Martinez-Salas E. Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation. J Virol 1997; 71:4171-5.
    • (1997) J Virol , vol.71 , pp. 4171-4175
    • Lopez De Quinto, S.1    Martinez-Salas, E.2
  • 21
    • 0032863246 scopus 로고    scopus 로고
    • A selection system for functional internal ribosome entry site (IRES) elements: Analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES
    • Robertson ME, Seamons RA, Belsham GJ. A selection system for functional internal ribosome entry site (IRES) elements: Analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES. RNA 1999; 5:1167-9.
    • (1999) RNA , vol.5 , pp. 1167-1169
    • Robertson, M.E.1    Seamons, R.A.2    Belsham, G.J.3
  • 22
    • 0033673387 scopus 로고    scopus 로고
    • Structures of the two RNA domains essential for hepatitis C virus internal ribosome entry site function
    • Lukavsky PJ, Otta GA, Lancaster AM, Sarnow P, Puglisi JD. Structures of the two RNA domains essential for hepatitis C virus internal ribosome entry site function. Nat Struc Biol 2000; 7:1105-10.
    • (2000) Nat Struc Biol , vol.7 , pp. 1105-1110
    • Lukavsky, P.J.1    Otta, G.A.2    Lancaster, A.M.3    Sarnow, P.4    Puglisi, J.D.5
  • 23
    • 0029811544 scopus 로고    scopus 로고
    • RNA-protein interactions in regulation of picornavirus RNA translation
    • Belsham GJ, Sonenberg N. RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol Rev 1996; 60:499-511.
    • (1996) Microbiol Rev , vol.60 , pp. 499-511
    • Belsham, G.J.1    Sonenberg, N.2
  • 24
    • 0028197298 scopus 로고
    • Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap- Independent initiation of translation
    • Pause A, Methot N, Svitkin Y, Merrick WC, Sonenberg N. Dominant negative mutants of mammalian translation initiation factor eIF-4A define a critical role for eIF-4F in cap-dependent and cap- independent initiation of translation. EMBO J 1994; 13:1205-15.
    • (1994) EMBO J , vol.13 , pp. 1205-1215
    • Pause, A.1    Methot, N.2    Svitkin, Y.3    Merrick, W.C.4    Sonenberg, N.5
  • 25
    • 0035032444 scopus 로고    scopus 로고
    • The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure
    • Svitkin YV, Pause A, Haghighat A, Pyronnet S, Witherell G, Belsham GJ, Sonenberg N. The requirement for eukaryotic initiation factor 4A (elF4A) in translation is in direct proportion to the degree of mRNA 5′ secondary structure. RNA 2001; 7:382-94.
    • (2001) RNA , vol.7 , pp. 382-394
    • Svitkin, Y.V.1    Pause, A.2    Haghighat, A.3    Pyronnet, S.4    Witherell, G.5    Belsham, G.J.6    Sonenberg, N.7
  • 26
    • 0034876991 scopus 로고    scopus 로고
    • Detailed analysis of the requirements of hepatitis A virus internal ribosome entry segment for the eukaryotic intiation factor complex eIF4F
    • Borman AM, Michel YM, Kean KM. Detailed analysis of the requirements of hepatitis A virus internal ribosome entry segment for the eukaryotic intiation factor complex eIF4F. J Virol 2001; 75:7864-71.
    • (2001) J Virol , vol.75 , pp. 7864-7871
    • Borman, A.M.1    Michel, Y.M.2    Kean, K.M.3
  • 27
    • 10644253021 scopus 로고    scopus 로고
    • Functional and structural similarities between the internal ribosome entry sites of hepatitis C virus and porcine teschovirus, a picornavirus
    • Pisarev AV, Chard LS, Kaku Y, Johns HL, Shatsky IN, Belsham GJ. Functional and structural similarities between the internal ribosome entry sites of hepatitis C virus and porcine teschovirus, a picornavirus. J Virol 2004; 78:4487-97.
    • (2004) J Virol , vol.78 , pp. 4487-4497
    • Pisarev, A.V.1    Chard, L.S.2    Kaku, Y.3    Johns, H.L.4    Shatsky, I.N.5    Belsham, G.J.6
  • 29
    • 3242700394 scopus 로고    scopus 로고
    • La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro
    • Costa-Mattioli M, Svitkin Y, Sonenberg N. La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro. Mol Cell Biol 2004; 20:6861-70.
    • (2004) Mol Cell Biol , vol.20 , pp. 6861-6870
    • Costa-Mattioli, M.1    Svitkin, Y.2    Sonenberg, N.3
  • 30
    • 0029397360 scopus 로고
    • Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal ribosomal entry site of encephalomyocarditis virus RNA
    • Kaminski A, Hunt SL, Patton JG, Jackson RJJ. Direct evidence that polypyrimidine tract binding protein (PTB) is essential for internal ribosomal entry site of encephalomyocarditis virus RNA. RNA 1995; 1:924-38.
    • (1995) RNA , vol.1 , pp. 924-938
    • Kaminski, A.1    Hunt, S.L.2    Patton, J.G.3    Jackson, R.J.J.4
  • 31
    • 0030847041 scopus 로고    scopus 로고
    • Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA
    • Blyn LB, Towner JS, Semler BL, Ehrenfeld E. Requirement of poly(rC) binding protein 2 for translation of poliovirus RNA. J Virol 1997; 71:6243-46.
    • (1997) J Virol , vol.71 , pp. 6243-6246
    • Blyn, L.B.1    Towner, J.S.2    Semler, B.L.3    Ehrenfeld, E.4
  • 32
    • 0030861261 scopus 로고    scopus 로고
    • Two functional complexes formed by KH domain containing proteins with the 5′ noncoding region of poliovirus RNA
    • Gamarnik AV, Andino R. Two functional complexes formed by KH domain containing proteins with the 5′ noncoding region of poliovirus RNA. RNA 1997; 3:882-92.
    • (1997) RNA , vol.3 , pp. 882-892
    • Gamarnik, A.V.1    Andino, R.2
  • 33
    • 0032806372 scopus 로고    scopus 로고
    • Differential utilization of poly (rC) binding protein 2 in translation directed by picornavirus IRES elements
    • Walter BL, Nguyen JH, Ehrenfeld E, Semler BL. Differential utilization of poly (rC) binding protein 2 in translation directed by picornavirus IRES elements. RNA 1999; 5:1570-85.
    • (1999) RNA , vol.5 , pp. 1570-1585
    • Walter, B.L.1    Nguyen, J.H.2    Ehrenfeld, E.3    Semler, B.L.4
  • 34
    • 0033557935 scopus 로고    scopus 로고
    • unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA
    • Hunt SL, Hsuan JJ, Totty N, Jackson RJ. unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. Genes Dev 1999; 13:437-48.
    • (1999) Genes Dev , vol.13 , pp. 437-448
    • Hunt, S.L.1    Hsuan, J.J.2    Totty, N.3    Jackson, R.J.4
  • 35
    • 3142757866 scopus 로고    scopus 로고
    • La Protein Binding at the GCAC Site near the initiator AUG facilitates the ribosomal assembly on the hepatitis C virus RNA to influence internal ribosome entry site-mediated translation
    • Pudi R, Srinivasan P, Das S. La Protein Binding at the GCAC Site near the initiator AUG facilitates the ribosomal assembly on the hepatitis C virus RNA to influence internal ribosome entry site-mediated translation. J Biol Chem 2004; 279:29879 -88.
    • (2004) J Biol Chem , vol.279 , pp. 29879-29888
    • Pudi, R.1    Srinivasan, P.2    Das, S.3
  • 36
    • 0034996730 scopus 로고    scopus 로고
    • Nucleolin stimulates viral internal ribosome entry site-mediated translation
    • Izumi RE, Valdez B, Banerjee R, Srivastava M, Dasgupta A.. Nucleolin stimulates viral internal ribosome entry site-mediated translation. Virus Res 2001; 76:17-29.
    • (2001) Virus Res , vol.76 , pp. 17-29
    • Izumi, R.E.1    Valdez, B.2    Banerjee, R.3    Srivastava, M.4    Dasgupta, A.5
  • 37
    • 0033934137 scopus 로고    scopus 로고
    • Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): Opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function
    • Yi M, Schultz DE, Lemon SM. Functional significance of the interaction of hepatitis A virus RNA with glyceraldehyde 3-phosphate dehydrogenase (GAPDH): Opposing effects of GAPDH and polypyrimidine tract binding protein on internal ribosome entry site function. J Virol 2000; 74:6459-68.
    • (2000) J Virol , vol.74 , pp. 6459-6468
    • Yi, M.1    Schultz, D.E.2    Lemon, S.M.3
  • 38
    • 0028295819 scopus 로고
    • Eukaryotic transcription termination factor la mediates transcript release and facilitates reinitiation by RNA polymerase III
    • Maraia RJ, Kenan DJ, Keene JD. Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III. Mol Cell Biol 1994; 14:2147-58.
    • (1994) Mol Cell Biol , vol.14 , pp. 2147-2158
    • Maraia, R.J.1    Kenan, D.J.2    Keene, J.D.3
  • 39
    • 0034903676 scopus 로고    scopus 로고
    • The la antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo
    • Ford LP, Shay JW, Wright WE. The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo. RNA 2001; 7:1068-75.
    • (2001) RNA , vol.7 , pp. 1068-1075
    • Ford, L.P.1    Shay, J.W.2    Wright, W.E.3
  • 40
    • 0028217897 scopus 로고
    • The la antigen inhibits the activation of the interferon inducible protein kinase PKR by sequestering and unwinding double-stranded RNA
    • Xiao Q, Sharp TV, Jeffrey IW, James MC, Pruijn GJM, Venrooij WJV, Clemens MJ. The La antigen inhibits the activation of the interferon inducible protein kinase PKR by sequestering and unwinding double-stranded RNA. Nucl Acids Res 1994; 22:2512-8.
    • (1994) Nucl Acids Res , vol.22 , pp. 2512-2518
    • Xiao, Q.1    Sharp, T.V.2    Jeffrey, I.W.3    James, M.C.4    Pruijn, G.J.M.5    Venrooij, W.J.V.6    Clemens, M.J.7
  • 41
    • 0034623002 scopus 로고    scopus 로고
    • Human la autoantigen is required for the hepatitis C virus internal ribosome entry site-mediated translation
    • Ali N, Pruijn GJ, Kenan DJ, Keene DJ, Siddiqui A. Human La autoantigen is required for the hepatitis C virus internal ribosome entry site-mediated translation. J Biol Chem 2000; 275:27531-40.
    • (2000) J Biol Chem , vol.275 , pp. 27531-27540
    • Ali, N.1    Pruijn, G.J.2    Kenan, D.J.3    Keene, D.J.4    Siddiqui, A.5
  • 42
    • 0034121076 scopus 로고    scopus 로고
    • Functional characterization of the X-linked inhibitor of Apoptosis (XIAP) internal ribosome entry site element: Role of la autoantigen in XIAP translation
    • Holcik M, Korneluk RG. Functional characterization of the X-linked inhibitor of Apoptosis (XIAP) internal ribosome entry site element: Role of La autoantigen in XIAP translation. Mol Cell Biol 2000; 20:4648-57.
    • (2000) Mol Cell Biol , vol.20 , pp. 4648-4657
    • Holcik, M.1    Korneluk, R.G.2
  • 43
    • 0037109166 scopus 로고    scopus 로고
    • La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA
    • Ray PS, Das S. La autoantigen is required for the internal ribosome entry site-mediated translation of Coxsackievirus B3 RNA. Nucl Acids Res 2002; 30:4500-8.
    • (2002) Nucl Acids Res , vol.30 , pp. 4500-4508
    • Ray, P.S.1    Das, S.2
  • 44
    • 0038485613 scopus 로고    scopus 로고
    • Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human la autoantigen
    • Pudi R, Abhiman S, Srinivasan N, Das S. Hepatitis C virus internal ribosome entry site-mediated translation is stimulated by specific interaction of independent regions of human La autoantigen. J Biol Chem 2003; 278:12231-40.
    • (2003) J Biol Chem , vol.278 , pp. 12231-12240
    • Pudi, R.1    Abhiman, S.2    Srinivasan, N.3    Das, S.4
  • 45
    • 0037229799 scopus 로고    scopus 로고
    • A Shine-Dalgarno-like sequence mediates in vitro ribosomal internal entry and subsequent scanning for translation initiation of Coxsackievirus B3 RNA
    • Yang D, Cheung P, Sun Y, Yuan J, Zhang H, Carthy CM, Anderson DR, Bohunek L, Wilson JE, Mcmanus BM. A Shine-Dalgarno-like sequence mediates in vitro ribosomal internal entry and subsequent scanning for translation initiation of Coxsackievirus B3 RNA. Virology 2003; 305:31-43.
    • (2003) Virology , vol.305 , pp. 31-43
    • Yang, D.1    Cheung, P.2    Sun, Y.3    Yuan, J.4    Zhang, H.5    Carthy, C.M.6    Anderson, D.R.7    Bohunek, L.8    Wilson, J.E.9    Mcmanus, B.M.10
  • 46
    • 0029331431 scopus 로고
    • An RNA pseudoknot is essential for internal initiation of translation of the hepatitis C virus RNA genome
    • Wang C, Le SY, Ali N, Siddiqui A. An RNA pseudoknot is essential for internal initiation of translation of the hepatitis C virus RNA genome. RNA 1995; 1:526-37.
    • (1995) RNA , vol.1 , pp. 526-537
    • Wang, C.1    Le, S.Y.2    Ali, N.3    Siddiqui, A.4
  • 47
    • 0031060497 scopus 로고    scopus 로고
    • Internal entry of ribosomes is directed by the 5′ noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon
    • Rijnbrand R, van der Straaten T, van Rijn P, Spaan WJM, Bredenbeek PJ. Internal entry of ribosomes is directed by the 5′ noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon. J Virol 1997; 71:451-7.
    • (1997) J Virol , vol.71 , pp. 451-457
    • Rijnbrand, R.1    Van Der Straaten, T.2    Van Rijn, P.3    Spaan, W.J.M.4    Bredenbeek, P.J.5


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