A selection system for functional internal ribosome entry site (IRES) elements: Analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES

RNA

Volumn 5, Issue 9, 1999, Pages 1167-1179

  Robertson, Morwenna E M ^a   Seamons, Rachael A ^a   Belsham, Graham J ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

GNRA tetraloop; Picornavirus; Protein synthesis; RNA interactions; RNA structure

Indexed keywords

RECOMBINANT DNA; VIRUS RNA;

ANIMAL CELL; ARTICLE; CELL SELECTION; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA TRANSFECTION; ENCEPHALOMYOCARDITIS VIRUS; NONHUMAN; PICORNAVIRUS; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA ANALYSIS; RNA CONFORMATION; RNA TRANSLATION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; VIRUS MUTANT;

ANIMALS; BASE SEQUENCE; CELL LINE; CONSERVED SEQUENCE; COS CELLS; ENCEPHALOMYOCARDITIS VIRUS; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEIC ACID CONFORMATION; PLASMIDS; POLYMERASE CHAIN REACTION; RIBOSOMES; RNA, MESSENGER; RNA, VIRAL; SEQUENCE ANALYSIS, RNA; TRANSFECTION; VACCINIA VIRUS;

ANIMALIA; ENCEPHALOMYOCARDITIS VIRUS; ESCHERICHIA COLI; MAMMALIA; PICORNAVIRIDAE; RNA VIRUSES;

EID: 0032863246     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838299990301     Document Type: Article

References (29)

1. Belsham GJ. 1997. Analysis of picornavirus internal ribosome entry site function in vivo. In: Richter J, ed. mRNA formation and function. New York: Academic Press, pp 323-340.
2. Belsham GJ, Sonenberg N. 1996. RNA protein interactions in regulation of picornavirus RNA translation. Microbiol Rev 60:499-511.
3. Borman AM, Deliat FG, Kean KM. 1994. Sequences within the poliovirus internal ribosome entry segment control viral-RNA synthesis. EMBO J 13:3149-3157.
4. Cate JH, Gooding AR, Podell E, Zhou K, Golden BL, Kundrot CE, Cech TR, Doudna JA. 1996a. Crystal structure of a group I ribozyme domain: Principles of RNA packing. Science 273:1678-1685.
5. Cate JH, Gooding AR, Podell E, Zhou KH, Golden BL, Szewczak AA, Kundrot CE, Cech TR, Doudna JA. 1996b. RNA tertiary structure mediation by adenosine platforms. Science 273:1696-1699.
6. Costa M, Michel F. 1995. Frequent use of the same tertiary motif by self-folding RNAs. EMBO J 14:1276-1285.
7. Costa M, Michel F. 1997. Rules for RNA recognition of GNRA tetraloops deduced by in vitro selection: Comparison with in vivo evolution. EMBO J 16:3289-3302.
8. Drew J, Belsham GJ. 1994. Trans complementation of defective foot-and-mouth disease virus internal ribosome entry site elements. J Virol 68:697-703.
9. Evan GI, Lewis GK, Ramsay G, Bishop KM. 1985. Isolation of monoclonal antibodies specific for c-myc proto-oncogene product. Mol Cell Biol 5:3610-3616.
10. Fuerst TR, Niles EG, Studier FW, Moss B. 1986. Eukaryotic transient expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc Natl Acad Sci USA 83:8122-8126.
11. Glück A, Endo A, Wool IG. 1992. Ribosomal RNA identity elements for ricin A chain recognition and catalysis. Analysis with tetraloop mutants. J Mol Biol 226:411-424.
12. Haller AA, Semler BL. 1992. Linker scanning mutagenesis of the internal ribosome entry site of poliovirus RNA. J Virol 66:5075-5086.
13. Hirt B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol 26:365-369.
14. Jackson RJ, Kaminski A. 1995. Internal initiation of translation in eukaryotes: The picornavirus paradigm and beyond. RNA 1:985-1000.
15. Jefferson RA, Burgess SM, Hirsh D. 1986. β-glucuronidase from Escherichia coli as a gene-fusion marker. Proc Natl Acad Sci USA 83:8447-8451.
16. Kaminski A, Hunt SL, Gibbs CL, Jackson RJ. 1994. Internal initiation of mRNA translation in eukaryotes. In: Setlow JK, ed. Genetic engineering, Vol. 16, New York: Plenum Press, pp 115-155.
17. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
18. Legault P, Li J, Mogridge J, Kay LE, Greenblatt J. 1998. NMR structure of the bacteriophage λ N peptide/boxB RNA complex: Recognition of a GNRA fold by an arginine-rich motif. Cell 93:289-299.
19. Lopez de Quinto S, Martinez-Salas E. 1997. Conserved structural motifs located in distal loops of aphthovirus internal ribosome entry site domain 3 are required for internal initiation of translation. J Virol 71:4171-4175.
20. Macadam AJ, Ferguson G, Fleming T, Stone DM, Almond JW, Minor PD. 1994. Role for poliovirus 2A in cap independent translation. EMBO J 13:324-927.
21. Macejak DG, Sarnow P. 1991. Internal initiation of translation mediated by the 5′ leader of a cellular mRNA. Nature (London) 353:90-94.
22. Merrick WC, Hershey JWB. 1996. The pathway and mechanism of eukaryotic protein synthesis. In: Hershey JWB, Mathews MB, Sonenberg N, eds. Translational control. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press, pp 31-69.
23. Mulder J, Robertson MEM, Seamons RA, Belsham GJ. 1998. Vaccinia virus protein synthesis has a low requirement for the intact translation initiation factor e1F4F, the cap-binding complex within infected cells. J Virol 72:8813-8819.
24. Pilipenko EV, Gmyl AP, Maslova SV, Svitkin YV, Sinyakov AN, Agol VI. 1992. Procaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA. Cell 68:119-131.
25. Pley HW, Flaherty KM, McKay DB. 1994. Model for an RNA tertiary interaction from the structure of an intermolecular complex between a GAAA tetraloop and an RNA helix. Nature (London) 372:111-113.
26. Roberts LO, Belsham GJ. 1997. Complementation of defective picornavirus internal ribosome entry site (IRES) elements by the coexpression of fragments of the IRES. Virology 227:53-62.
27. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: A laboratory manual. 2nd ed. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press.
28. van der Velden A, Kaminski A, Jackson RJ, Belsham GJ. 1995. Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans. Virology 214:82-90.
29. Woese CR, Winker S, Gutell RR. 1990. Architecture of ribosomal-RNA constraints on the sequence of tetra-loops. Proc Natl Acad Sci USA 87:8467-8471.