The Clinical Application of Intensity-Modulated Radiation Therapy

Seminars in Radiation Oncology

Volumn 16, Issue 4, 2006, Pages 224-231

  Ten Haken, Randall K ^a   Lawrence, Theodore S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

IMRT; radiotherapy treatment planning optimization

Indexed keywords

ARTICLE; CLINICAL PRACTICE; COMPUTER ASSISTED RADIOTHERAPY; HEAD AND NECK CANCER; HUMAN; INTENSITY MODULATED RADIATION THERAPY; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RADIATION INJURY; TREATMENT PLANNING;

HUMANS; NEOPLASMS; RADIATION DOSAGE; RADIOTHERAPY, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED;

EID: 33748934406     PISSN: 10534296     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.semradonc.2006.04.005     Document Type: Article

References (53)

1. Mackie T.R., Kapatoes J., Ruchala K., Lu W., et al. Image guidance for precise conformal radiotherapy. Int J Radiat Oncol Biol Phys 56 (2003) 89-105
2. Woo S.Y., Grant III W.H., Bellezza D., et al. A comparison of intensity modulated conformal therapy with a conventional external beam stereotactic radiosurgery system for the treatment of single and multiple intracranial lesions. Int J Radiat Oncol Biol Phys 35 (1996) 593-597
3. Verellen D., Linthout N., van den Berge D., et al. Initial experience with intensity-modulated conformal radiation therapy for treatment of the head and neck region. Int J Radiat Oncol Biol Phys 39 (1997) 99-114
4. Boyer A.L., Geis P., Grant W., et al. Modulated beam conformal therapy for head and neck tumors. Int J Radiat Oncol Biol Phys 39 (1997) 227-236
5. Zelefsky M.J., Fuks Z., Happersett L., et al. Clinical experience with intensity modulated radiation therapy (IMRT) in prostate cancer. Radiother Oncol 55 (2000) 241-249
6. Xia P., Fu K.K., Wong G.W., et al. Comparison of treatment plans involving intensity-modulated radiotherapy for nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 48 (2000) 329-337
7. Pirzkall A., Carol M., Lohr F., et al. Comparison of intensity-modulated radiotherapy with conventional conformal radiotherapy for complex-shaped tumors. Int J Radiat Oncol Biol Phys 48 (2000) 1371-1380
8. Chen Y.J., Liu A., Tsai P.T., et al. Organ sparing by conformal avoidance intensity-modulated radiation therapy for anal cancer: dosimetric evaluation of coverage of pelvis and inguinal/femoral nodes. Int J Radiat Oncol Biol Phys 63 (2005) 274-281
9. Xia P., Pickett B., Vigneault E., et al. Forward or inversely planned segmental multileaf collimator IMRT and sequential tomotherapy to treat multiple dominant intraprostatic lesions of prostate cancer to 90 Gy. Int J Radiat Oncol Biol Phys 51 (2001) 244-254
10. Xing L., Cotrutz C., Hunjan S., et al. Inverse planning for functional image-guided intensity-modulated radiation therapy. Phys Med Biol 47 (2002) 3567-3578
11. Baumert B.G., Norton I.A., and Davis J.B. Intensity-modulated stereotactic radiotherapy vs. stereotactic conformal radiotherapy for the treatment of meningioma located predominantly in the skull base. Int J Radiat Oncol Biol Phys 57 (2003) 580-592
12. Vineberg K.A., Eisbruch A., Coselmon M.M., et al. Is uniform target dose possible in IMRT plans in the head and neck?. Int J Radiat Oncol Biol Phys 52 (2002) 1159-1172
13. Eisbruch A., Foote R.L., O'Sullivan B., et al. Intensity-modulated radiation therapy for head and neck cancer: Emphasis on the selection and delineation of the targets. Semin Radiat Oncol 12 (2002) 238-249
14. Clark C.H., Bidmead A.M., Mubata C.D., et al. Intensity-modulated radiotherapy improves target coverage, spinal cord sparing and allows dose escalation in patients with locally advanced cancer of the larynx. Radiother Oncol 70 (2004) 189-198
15. Cozzi L., Fogliata A., Bolsi A., et al. Three-dimensional conformal vs. intensity-modulated radiotherapy in head-and-neck cancer patients: comparative analysis of dosimetric and technical parameters. Int J Radiat Oncol Biol Phys 58 (2004) 617-624
16. Kestin L.L., Sharpe M.B., Frazier R.C., et al. Intensity modulation to improve dose uniformity with tangential breast radiotherapy: Initial clinical experience. Int J Radiat Oncol Biol Phys 48 (2000) 1559-1568
17. Krueger E.A., Fraass B.A., and Pierce L.J. Clinical aspects of intensity-modulated radiotherapy in the treatment of breast cancer. Semin Radiat Oncol 12 (2002) 250-259
18. Tome W.A., and Fowler J.F. On cold spots in tumor subvolumes. Med Phys 29 (2002) 1590-1598
19. Niemierko A. A generalized concept of equivalent uniform dose (EUD). Med Phys 26 (1999) 1100 (abstr)
20. Butler E.B., Teh B.S., Grant III W.H., et al. Smart (simultaneous modulated accelerated radiation therapy) boost: A new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys 45 (1999) 21-32
21. Mohan R., Wu Q., Manning M., et al. Radiobiological considerations in the design of fractionation strategies for intensity-modulated radiation therapy of head and neck cancers. Int J Radiat Oncol Biol Phys 46 (2000) 619-630
22. Lauve A., Morris M., Schmidt-Ullrich R., et al. Simultaneous integrated boost intensity-modulated radiotherapy for locally advanced head-and-neck squamous cell carcinomas: II-Clinical results. Int J Radiat Oncol Biol Phys 60 (2004) 374-387
23. Tome W.A., and Fowler J.F. Selective boosting of tumor subvolumes. Int J Radiat Oncol Biol Phys 48 (2000) 593-599
24. Deasy J.O. Partial tumor boosts: Even more attractive than theory predicts?. Int J Radiat Oncol Biol Phys 51 (2001) 279-280
25. Schwarz M., Alber M., Lebesque J.V., et al. Dose heterogeneity in the target volume and intensity-modulated radiotherapy to escalate the dose in the treatment of non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 62 (2005) 561-570
26. Thomas E., Chapet O., Kessler M.L., et al. Benefit of using biologic parameters (EUD and NTCP) in IMRT optimization for treatment of intrahepatic tumors. Int J Radiat Oncol Biol Phys 62 (2005) 571-578
27. Chapet O., Thomas E., Kessler M.L., et al. Esophagus sparing with IMRT in lung tumor irradiation: An EUD-based optimization technique. Int J Radiat Oncol Biol Phys 63 (2005) 179-187
28. Tsien C., Eisbruch A., McShan D., et al. Intensity-modulated radiation therapy (IMRT) for locally advanced paranasal sinus tumors: incorporating clinical decisions in the optimization process. Int J Radiat Oncol Biol Phys 55 (2003) 776-784
29. Lopez C.A., Pan C.C., Sandler H.M., et al. Early results of a prospective randomized trial comparing proximal urethra sparing IMRT and standard prostate IMRT in low-risk prostate cancer patients. Program Guide to the 2005 Scientific Assembly of the RSNA (2005) 455 Chicago, IL, November (abstr)
30. Hong T.S., Tome W.A., Chappell R.J., et al. The impact of daily setup variations on head-and-neck intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 61 (2005) 779-788
31. Ploquin N., Song W., Lau H., et al. Intensity modulated radiation therapy for oropharyngeal cancer: The sensitivity of plan objectives and constraints to set-up uncertainty. Phys Med Biol 50 (2005) 3515-3533
32. Litzenberg D.W., Balter J.M., Lam K.L., et al. Retrospective analysis of prostate cancer patients with implanted gold markers using off-line and adaptive therapy protocols. Int J Radiat Oncol Biol Phys 63 (2005) 123-133
33. Balter J.M., Brock K.K., Lam K.L., et al. Evaluating the influence of setup uncertainties on treatment planning for focal liver tumors. Int J Radiat Oncol Biol Phys 63 (2005) 610-614
34. Seppenwoolde Y., Shirato H., Kitamura K., et al. Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. Int J Radiat Oncol Biol Phys 53 (2002) 822-834
35. Dawson L.A., and Balter J.M. Interventions to reduce organ motion effects in radiation delivery. Semin Radiat Oncol 14 (2004) 76-80
36. Bortfeld T., Jiang S.B., and Rietzel E. Effects of motion on the total dose distribution. Semin Radiat Oncol 14 (2004) 41-51
37. Pollack A., Zagars G.K., Starkschall G., et al. Prostate cancer radiation dose response: Results of the M. D. Anderson phase III randomized trial Int. J Radiat Oncol Biol Phys 53 (2002) 1097-1105
38. Lebesque J.V., Peeters S.T.H., van Putten W.L.J., et al. Radiation dose-response in prostate cancer: Results of a multicenter randomized phase III trial comparing 68Gy with 78Gy. Eur J Cancer Suppl 3 (2005) 1 (abstr)
39. Symon Z., Griffith K.A., McLaughlin P.W., et al. Dose escalation for localized prostate cancer: Substantial benefit observed with 3D conformal therapy. Int J Radiat Oncol Biol Phys 57 (2003) 384-390
40. Teh B.S., Amosson C.M., Mai W.Y., et al. Intensity modulated radiation therapy (IMRT) in the management of prostate cancer. Cancer Invest 22 (2004) 913-924
41. Zelefsky M.J., Fuks Z., Hunt M., et al. High-dose intensity modulated radiation therapy for prostate cancer: early toxicity and biochemical outcome in 772 patients. Int J Radiat Oncol Biol Phys 53 (2002) 1111-1116
42. Michalski J.M., Winter K., Purdy J.A., et al. Toxicity after three-dimensional radiotherapy for prostate cancer with RTOG 9406 dose level IV. Int J Radiat Oncol Biol Phys 58 (2004) 735-742
43. Hong T.S., Ritter M.A., Tome W.A., et al. Intensity-modulated radiation therapy: Emerging cancer treatment technology. Br J Cancer 92 (2005) 1819-1824
44. Gregoire V., and Maingon P. Intensity modulated radiation therapy in head and neck squamous cell carcinoma: State of the art and future challenges. Cancer Radiother 9 (2005) 42-50
45. Eisbruch A. Intensity-modulated radiation therapy in the treatment of head and neck cancer. Nat Clin Pract Oncol 2 (2005) 34-39
46. Fu K.K., Pajak T.F., Trotti A., et al. A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: First report of RTOG 9003. Int J Radiat Oncol Biol Phys 48 (2000) 7-16
47. Pignon J.P., Bourhis J., Domenge C., et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: Three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-analysis of chemotherapy on head and neck cancer. Lancet 355 (2000) 949-955
48. Kam M.K., Leung S.F., Zee B., et al. Impact of intensity-modulated radiotherapy (IMRT) on salivary gland function in early-stage nasopharyngeal carcinoma (NPC) patients: A prospective randomized study. J Clin Oncol 23 (2005) 5501 ASCO Annual Meeting Proceedings (abstr)
49. Dawson L.A., Anzai Y., Marsh L., et al. Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 46 (2000) 1117-1126
50. Lee N., Xia P., Quivey J.M., et al. Intensity-modulated radiotherapy in the treatment of nasopharyngeal carcinoma: An update of the UCSF experience. Int J Radiat Oncol Biol Phys 53 (2002) 12-22
51. Chao K.S., Low D.A., Perez C.A., et al. Intensity-modulated radiation therapy in head and neck cancers: The Mallinckrodt experience. Int J Cancer 90 (2000) 92-103
52. Yarnold J., Donovan E., Bleackley N., et al. Randomised trial of standard 2D radiotherapy (RT) versus 3D intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Clin Oncol 14 (2002) S40 (abstr)
53. Mundt A.J., Mell L.K., and Roeske J.C. Preliminary analysis of chronic gastrointestinal toxicity in gynecology patients treated with intensity-modulated whole pelvic radiation therapy. Int J Radiat Oncol Biol Phys 56 (2003) 1354-1360