Intensity-modulated radiotherapy improves target coverage, spinal cord sparing and allows dose escalation in patients with locally advanced cancer of the larynx

Radiotherapy and Oncology

Volumn 70, Issue 2, 2004, Pages 189-198

  Clark, Catharine H ^a   Bidmead, A Margaret ^a   Mubata, Cephas D ^a   Harrington, Kevin J ^a   Nutting, Christopher M ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

Dose escalation; Intensity modulated radiotherapy; Larynx carcinoma

Indexed keywords

ADVANCED CANCER; CANCER LOCALIZATION; CANCER PATIENT; CERVICAL LYMPH NODE; CLINICAL ARTICLE; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LARYNX CANCER; PRIORITY JOURNAL; RADIATION DOSE; SPINAL CORD;

DOSE FRACTIONATION; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FOLLOW-UP STUDIES; HUMANS; LARYNGEAL NEOPLASMS; LYMPH NODES; MALE; NEOPLASM STAGING; PROSPECTIVE STUDIES; RADIATION INJURIES; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RISK ASSESSMENT; SAMPLING STUDIES; SPINAL CORD; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 1542393643     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2003.10.012     Document Type: Conference Paper

References (29)

1. Bragg C.M., Conway J., Robinson M.H. The role of intensity-modulated radiotherapy in the treatment of parotid tumors. Int J Radiat Oncol Biol Phys. 52:2002;729-738.
2. Brahme A., Lax I., Andreo P. Electron beam dose planning using discrete Gaussian beams. Mathematical background. Acta Radiol Oncol. 20:1981;147-158.
3. Butler E.B., Teh B.S., Grant W.H. III, et al. SMART (simultaneous modulated accelerated radiation therapy) boost: a new accelerated fractionation schedule for the treatment of head and neck cancer with intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys. 45:1999;21-32.
4. Cardinale R.M., Benedict S.H., Wu Q., et al. A comparison of three stereotactic radiotherapy techniques; arcs vs noncoplanar fixed fields vs intensity modulation. Int J Radiat Oncol Biol Phys. 42:1998;431-436.
5. Clark C.H., Mubata C.D., Meehan C.A., Bidmead A.M., Staffurth J.N., Dearnaley D.P. IMRT clinical implementation: prostate and pelvic node irradiation by Helios using a 120-leaf MLC. J Appl Clin Med Phys. 3:(4):2002.
6. De Neve W., De Gersem W., Derycke S., et al. Clinical delivery of intensity modulated conformal radiotherapy for relapsed or second-primary head and neck cancer using a multileaf collimator with dynamic control. Radiother Oncol. 50:(3):1999;301-314.
7. Dobbs J., Barrett A., Ash D. Practical radiotherapy planning. 3rd ed:1999;Arnold.
8. Eisbruch A., Marsh L.H., Martel M.K., et al. Comprehensive irradiation of head and neck cancer using conformal multisegmental fields: assessment of target coverage and non-involved tissue sparing. Int J Radiat Oncol Biol Phys. 41:1998;559-568.
9. Fletcher G.H. Elective irradiation of subclinical disease in cancers of the head and neck. Cancer. 29:(6):1972;1450-1454.
10. Fu K.K., Pajak T.F., Trotti A., et al. A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003. Int J Radiat Oncol Biol Phys. 48:(1):2000;7-16.
11. Gregoire V., Coche E., Cosnard G., et al. Selection and delineation of lymph node target volumes in head and neck conformal radiotherapy. Proposal for standardizing terminology and procedure based on the surgical experience. Radiother Oncol. 56:(2):2000;135-150.
12. Henk J.M. Controlled trials of synchronous chemotherapy with radiotherapy in head and neck cancer: overview of radiation morbidity. Clin Oncol (R Coll Radiol). 9:(5):1997;308-312.
13. Humphries M, Bidmead M. Assessment of treatment accuracy in head and neck radiotherapy using electronic portal imaging. The Seventh International Workshop on Electronic Portal Imaging-EPI2K2, Vancouver, BC; June 27-29, 2002.
14. ICRU 50. Prescribing, recording and reporting photon beam therapy ICRU report 50. 1993;International Commission on Radiation Units and Measurement, Bethesda.
15. ICRU 62. Prescribing, recording and reporting photon beam therapy (Supplement to ICRU Report 50). 1999;International Commission on Radiation Units and Measurement, Bethesda.
16. Khoo V.S., Oldham M., Adams E.J., et al. Comparison of intensity modulated tomotherapy with stereotactically guided conformal radiotherapy for brain tumours. Int J Radiat Oncol Biol Phys. 45:1999;415-425.
17. Lax I., Brahme A. Electron beam dose planning using Gaussian beams. Energy and spatial scaling with inhomogeneities. Acta Radiol Oncol. 24:1985;75-85.
18. Lax I., Brahme A., Andreo P. Electron beam dose planning using Gaussian beams. Improved radial dose profiles. Acta Radiol Suppl. 364:1983;49-59.
19. Lefebre J.L., Chevalier D., Luboinski B., et al. Larynx preservation in pyriform sinus cancer: preliminary results of a European organization for research and treatment of cancer phase III trial. J Natl Cancer Inst. 88:(13):1996;890-899.
20. Miles E.A., Clark C.H., Guerrero Urbano M.T., et al. How routine can IMRT become in daily clinical practice? Clin Oncol. 15:(2):2003;S30.
21. Nutting C.M., Convery D.J., Cosgrove V.P., et al. Improvements in target coverage and reduced spinal cord irradiation using intensity-modulated radiotherapy (IMRT) in patients with carcinoma of the thyroid gland. Radiother Oncol. 60:2001;173-180.
22. Nutting C.M., Dearnaley D.P., Webb S. Intensity modulated radiotherapy: a clinical review. Br J Radiol. 54:2000;459-469.
23. Nutting C.M., Rowbottom C., Cosgrove V.P., et al. Optimisation of radiotherapy for carcinoma of the parotid gland: a comparison of conventional, three-dimensional conformal, and intensity-modulated techniques. Radiother Oncol. 60:2001;163-172.
24. Perez C.A., Brady L. Principles and practice of radiation oncology. 1987;Lippincott, Philadelphia, PA.
25. Pignon J.P., Bourhis J., Domenge C., et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-analysis of chemotherapy on head and neck cancer. Lancet. 18:(9208):2000;949-955.
26. Rowbottom C.G., Nutting C.M., Webb S. Beam-orientation optimization of intensity-modulated radiotherapy: clinical application to parotid gland tumours. Radiother Oncol. 59:(2):2001;169-177.
27. Storchi P.R.M., van Battum L.J., Woudstra E. Calculation of a pencil beam kernel from measured photon beam data. Phys Med Biol. 44:1999;2917-2928.
28. The Department of Veteran Affairs Laryngeal Cancer Study Group. Induction chemotherapy plus radiation compared with surgery plus radiation in patients with advanced laryngeal cancer. N Engl J Med. 324:(24):1992;1685-1690.
29. Webb S. The physics of conformal radiotherapy. 1st ed Advances in technology. 1997;Medical Science Series, IOP.