The induction of surface β-amyloid binding proteins and enhanced cytotoxicity in cultured PC-12 and IMR-32 cells by advanced glycation end products

Neuroscience

Volumn 142, Issue 2, 2006, Pages 463-473

  Mruthinti, S ^a,b   Sood, A ^a   Humphrey, C L ^a   Swamy Mruthinti, S ^c   Buccafusco, J J ^a,b  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF WEST GEORGIA   (United States)

Author keywords

advanced glycation end products; Alzheimer's disease; amyloid precursor protein; beta amyloid; cytotoxicity; nicotinic acetylcholine receptors

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BOVINE SERUM ALBUMIN; CELL SURFACE RECEPTOR; LYSINE DERIVATIVE; NICOTINIC RECEPTOR;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CULTURE; CELL DEATH; CELL STRAIN; CELL SURFACE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TIME; MITOCHONDRIAL TOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; RAT; STATISTICAL SIGNIFICANCE;

AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GLYCOSYLATION END PRODUCTS, ADVANCED; HUMANS; MEMBRANE PROTEINS; NEUROBLASTOMA; PEPTIDE FRAGMENTS; PROTEIN BINDING; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, NICOTINIC;

EID: 33748806304     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.06.010     Document Type: Article

References (52)

1. Ahmed N. Advanced glycation end products: role in pathology of diabetic complications. Diabetes Res Clin Pract 67 (2005) 3-21
2. Anderson M.M., Requena J.R., Crowley J.R., Thorpe S.R., and Heinecke J. The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl) lysine on proteins: a mechanism for producing advanced glycation endproducts at sites of inflammation. J Clin Invest 104 (1999) 103-113
3. Bass D.A., Parce J.W., Dechatelet L.R., Szejda P., Seeds M.C., and Thomas M. Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation. J Immunol 130 (1983) 1910-1917
4. Buccafusco J.J. Neuronal nicotinic receptor subtypes: defining therapeutic targets. Mol Interv 4 (2004) 285-295
5. Burghaus L., Schutz U., Krempel U., de Vos R.A., Jansen Steur E.N., Wevers A., Lindstrom J., and Schroder H. Quantitative assessment of nicotinic acetylcholine receptor proteins in the cerebral cortex of Alzheimer patients. Brain Res Mol Brain Res 76 (2000) 385-388
6. Chavakis T., Bierhaus A., Al-Fakhri N., Schneider D., Witte S., Linn T., Nagashima M., Morser J., Arnold B., Preissner K.T., and Nawroth P.P. The pattern recognition receptor (RAGE) is a counterreceptor for leukocyte integrins: a novel pathway for inflammatory cell recruitment. J Exp Med 198 (2003) 1507-1515
7. Chen Y., Yan S.S., Colgan J., Zhang H.P., Luban J., Schmidt A.M., Stern D., and Herold K.C. Blockade of late stages of autoimmune diabetes by inhibition of the receptor for advanced glycation end products. J Immunol 173 (2004) 1399-1405
8. Colaco C.A., Ledesma M.D., Harrington C.R., and Avlia J. The role of the Maillard reaction in other pathologies: Alzheimer's disease. Nephrol Dial Transplant 11 Suppl 5 (1996) 7-12
9. Deane R., Du Yan S., Submamaryan R.K., LaRue B., Jovanovic S., Hogg E., Welch D., Manness L., Lin C., Yu J., Zhu H., Ghiso J., Frangione B., Stern A., Schmidt A.M., Armstrong D.L., Arnold B., Liliensiek B., and Nawroth P. RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain. Nat Med 9 (2003) 907-913
10. Dickerson T.B., and Janda K.D. Glycation of the amyloid β-protein by a nicotine metabolite: A fortuitous chemical dynamic between smoking and Alzheimer's disease. Proc Natl Acad Sci U S A 100 (2003) 8182-8187
11. Dunn J.A., McCance D.R., Thrope S.R., Lyons T.J., and Baynes J.W. Age dependent accumulation of N-ε-(carboxymethyl)lysine and N-ε-(carboxymethyl) hydroxylysine in human skin collagen. Biochemistry 30 (1991) 1205-1210
12. Fukuyama R., Chandrasekaran K., and Rapoport S.I. Nerve growth factor-induced neuronal differentiation is accompanied by differential induction and localization of the amyloid precursor protein (APP) in PC-12 and variant PC12S-cells. Mol Brain Res 17 (1993) 17-22
13. Guan Z.-Z., Yu W.-F., and Nordberg A. Dual effects of nicotine on oxidative stress and neuroprotection in PC-12 cells. Neurochem Int 43 (2003) 243-249
14. Herber D.L., Severance E.G., Cuevas J., Morgan D., and Gordon M.N. Biochemical and histochemical evidence of nonspecific binding of α7nAChR antibodies to mouse brain tissue. J Histochem Cytochem 52 (2004) 1367-1375
15. Heredia L., Lin R., Vigo S., Kedikian G., Busciglio J., and Lorenzo A. Deposition of amyloid fibrils promotes cell-surface accumulation of amyloid β precursor protein. Neurobiol Dis 16 (2004) 617-629
16. Hofmann M.A., Drury S., Fu C., Qu W., Taguchi A., Lu Y., Avila C., Kambham N., Bierhaus A., Nawroth P., Neurath M.F., Slattery T., Beach D., McClary J., Nagashima M., Morser J., Stern D., and Schmidt A.M. RAGE mediates a novel proinflammatory axis: a central cell surface receptor for S100/calgranulin polypeptides. Cell 97 (1999) 889-901
17. Horiuchi S., Araki N., and Morino Y. Immunochemical approach to characterize advanced glycation end products of the Millar reaction: evidence for the presence of a common structure. J Biol Chem 266 (1991) 7329-7332
18. Hudson B.I., Bucciarelli L.G., Wendt T., Sakaguchi T., Lalla E., Qu W., Lu Y., Lee L., Stern D.M., Naka Y., Ramasamy R., Yan S.D., Yan S.F., D'Agati V., and Schmidt A.M. Blockade of receptor for advanced glycation endproducts: a new target for therapeutic intervention in diabetic complications and inflammatory disorders. Arch Biochem Biophys 419 (2003) 80-88
19. Jiang J.M., Wang Z., and Li D.D. Effects of AGEs on oxidation stress and antioxidation abilities in cultured astrocytes. Biomed Environ Sci 17 (2004) 79-86
20. Jonnala R.R., and Buccafusco J.J. Relationship between cell surface α7 nicotinic receptor expression and neuroprotection induced by several nicotinic receptor agonists. J Neurosci Res 66 (2001) 565-572
21. Jung S.S., Gauthier S., and Cashman N.R. β-Amyloid precursor protein is detectable in monocyte and is increased in Alzheimer's disease. Neurobiol Aging 20 (1999) 249-257
22. Le Bel C., Ischiropoulos H., and Bondy S.C. Evaluation of the probe 2′,7′-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chem Res Toxicol 5 (1992) 227-231
23. Li X.D., and Buccafusco J.J. Effect of beta-amyloid peptide 1-42 on the cytoprotective action mediated by α7 nicotinic acetylcholine receptors in growth factor-deprived differentiated PC-12 cells. J Pharmacol Exp Ther 307 (2003) 670-675
24. Lue L.F., Yan S.D., Stern D.M., and Walker D.G. Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease. Curr Drug Targets CNS Neurol Disord 4 (2005) 249-266
25. Marchi M., Risso F., Viola C., Cavazzani P., and Raiteri M. Direct evidence that release-stimulating α7 nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals. J Neurochem 80 (2002) 1071-1078
26. Miklossy J., Kis A., Radenovic A., Miller L., Forro L., Martins R., Reiss K., Darbinian N., Darekar P., Mihaly L., and Khalili K. Beta-amyloid deposition and Alzheimer's type changes induced by Borrelia spirochetes. Neurobiol Aging 27 (2006) 228-236
27. Miyata T., Hori O., Zhang J., Yan S.D., Ferran L., Iida Y., and Schmidt A.M. The receptor for advanced glycation end products (RAGE) is a central mediator of the interaction of AGE-beta2microglobulin with human mononuclear phagocytes via an oxidant-sensitive pathway. Implications for the pathogenesis of dialysis-related amyloidosis. J Clin Invest 98 (1996) 1088-1094
28. Monnier V.M., Kohn R.R., and Cerami A. Nonenzymatic browning in-vivo: possible process for aging and long-lived proteins. Science 211 (1981) 491-493
29. Monnier V.M., Nagaraj R.H., Portero-Otin M., Glomb M., Elgawish A.H., Sell D.R., and Friedlander M.A. Structure of advanced Maillard reaction products and their pathological role. Nephrol Dial Transplant 11 Suppl 5 (1996) 20-26
30. Motomiya Y., Oyama N., Iwamoto H., Uchimura T., and Maruyama I. N epsilon-(carboxymethyl)lysine in blood from maintenance hemodialysis patients may contribute to dialysis-related amyloidosis. Kidney Int 54 (1998) 1357-1366
31. Mruthinti S., Buccafusco J.J., Hill W.D., Waller J.L., Jackson T.W., Zamrini E.Y., and Schade R.F. Autoimmunity in Alzheimer's disease: increased levels of circulating IgGs binding Aβ and RAGE peptides. Neurobiol Aging 25 (2004) 1023-1032
32. Münch G., Mayer S., Michaelis J., Hipkiss A.R., Riederer P., Müller R., Neumann A., Schinzel R., and Cunningham A.M. Influence of advanced glycation end-products and AGE-inhibitors on nucleation-dependent polymerization of beta-amyloid peptide. Biochim Biophys Acta 1360 (1997) 17-29
33. Münch G., Apelt J., Engel R.K., Stahl P., Juth H.J., and Schliebs R. Advanced glycation end products and pro-inflammatory cytokines in transgenic Tg2576 mice with amyloid plaque pathology. J Neurochem 86 (2003) 283-289
34. Nagele R.G., D'Andrea M.R., Anderson W.J., and Wang H.-Y. Accumulation of beta amyloid 1-42 in neurons is facilitated by the alpha 7 nicotinic acetylcholine receptor in Alzheimer's disease. Neuroscience 110 (2002) 199-211
35. Nakamura T., Shoji M., Harigaya Y., Watanabe M., Hosoda K., Cheung T.T., Shaffer L.M., Golde T.E., Younkin L.H., Younkin S.G., and Hirai S. Amyloid beta protein levels in cerebrospinal fluid are elevated in early-onset Alzheimer's disease. Ann Neurol 36 (1994) 903-911
36. Owen Jr. W.F., Hou F.F., Stuart R.O., Kay J., Boyce J., Chertow G.M., and Schmidt A.M. β2-Microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts. Kidney Int 53 (1998) 1365-1373
37. Sakaguchi T., Yan S.F., Yan S.D., Belov D., Rong L.L., Sousa M., Andrassy M., Marso S.P., Duda S., Arnold B., Liliensiek B., Nawroth P.P., Stern D.M., Schmidt A.M., and Naka Y. Central role of RAGE-dependent neointimal expansion in arterial restenosis. J Clin Invest 111 (2003) 959-972
38. Schmidt A.M., Yan S.D., Brett J., Mora R., and Stern D. Regulation of mononuclear phagocyte migration by cell surface binding proteins for advanced glycosylation endproducts. J Clin Invest 92 (1993) 2155-2168
39. Schmidt A.M., Yan S.D., Wautier J.L., and Stern D. Activation of receptor for advanced glycation end products. A mechanism for chronic vascular dysfunction in diabetic vasculopathy and atherosclerosis. Circ Res 84 (1998) 489-497
40. Schmidt A.M., Yan S.D., Yan S.F., and Stern D.M. The biology of receptor for advanced glycation end products and its ligands. Biochim Biophys Acta 1498 (2000) 99-111
41. Smith C.J., Wion D., and Brachet P. Nerve growth factor-induced neuronal differentiation is accompanied by differential splicing of beta amyloid precursor messenger RNAs in the PC12 cell line. Mol Brain Res 10 (1991) 351-354
42. Traverso N., Menini S., Maineri E.P., Patriarca S., Odetti P., Cottalasso D., Marinari U.M., and Pronzato M.A. Malondialdehyde, a lipoperoxidation-derived aldehyde, can bring about secondary oxidative damage to proteins. J Gerontol Biol Sci Med Sci 59 (2004) B890-B895
43. Vitek M.P., Bhattacharya K., Glendening J.M., Stopa E., Vlassara H., Bucala R., Manogue K., and Cerami A. Advanced glycation end products contribute to amyloidosis in Alzheimer's disease. Proc Natl Acad Sci USA 91 (1994) 4766-4770
44. Wang H.Y., Lee D.H.S., D'Andrea M.R., Peterson P.A., and Shank R.P. β-Amyloid 1-42 binds to α7 nicotinic acetylcholine receptor with high affinity. J Biol Chem 275 (2000) 5626-5632
45. Wang H., Yu M., Ochani M., Amella C.A., Tanovic M., Susarla S., Li J.H., Wang H., Yang H., Ulloa L., Al-Abed Y., Czura C.J., and Tracey K.J. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421 (2003) 384-388
46. Weidemann A., Konig G., Bunke D., Fischer P., Salbaum J.M., Masters C., and Beyreuther K. Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein. Cell 57 (1989) 115-126
47. Wevers A., Monteggia L., Nowacki S., Bloch W., Schutz U., Lindstrom J., Pereira E.F., Eisenberg H., Giacobini E., de Vos R.A., Steur E.N., Maelicke A., Albuquerque E.X., and Schroder H. Expression of nicotinic acetylcholine receptor subunits in the cerebral cortex in Alzheimer's disease: histotopographical correlation with amyloid plaques and hyperphosphorylated-tau protein. Eur J Neurosci 11 (1999) 2551-2565
48. Yamada T., Araki E., Izumi R., Goto I., Sasaki H., and Sakaki Y. Expression of Alzheimer amyloid-beta protein precursor gene in neuronal cells. Gerontology 37 (1991) 24-30
49. Yan S.D., Schmidt A.M., Anderson G., Zhang J., Brett J., Zou Y.S., Pinsky D., and Stern D. Enhanced cellular oxidant stress by the interaction of advanced glycation endproducts with their receptors/binding proteins. J Biol Chem 269 (1994) 9889-9897
50. Yan S.D., Chen X., Fu J., Chen M., Zhu H., Roher A., Slattery T., Zhao L., Nagashima M., Morser J., Migheli A., Nawroth P., Stern D., and Schmidt A.M. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease. Nature 382 (1996) 685-691
51. Yan H., and Harding J.J. Glycation-induced inactivation and loss of antigenicity of catalase and superoxide dismutase. Biochem J 328 (1997) 599-605
52. Yan S.D., Zhu H., Zhu A., Golabek A., Du H., Roher A., Yu J., Soto C., Schmidt A.M., Stern D., and Kindy M. Receptor dependent cell stress and amyloid accumulation in systemic amyloidosis. Nat Med 6 (2000) 643-651