Molecular characterization of a disease associated conformational epitope on GAD65 recognised by a human monoclonal antibody b96.11

Molecular Immunology

Volumn 44, Issue 6, 2007, Pages 1178-1189

  Fenalti, Gustavo ^a   Hampe, Christiane S ^b   O'Connor, Karen ^a   Banga, J Paul ^c   Mackay, Ian R ^a   Rowley, Merrill J ^a   El Kabbani, Ossama ^a  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF WASHINGTON   (United States)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antigen antibody interactions; Antigens peptides epitopes; Autoantibodies; Autoimmunity; Diabetes; GAD65; Homology modelling; Phage display; Protein protein docking; Type 1 diabetes

Indexed keywords

AMINO ACID; EPITOPE; GLUTAMATE DECARBOXYLASE 65; GLUTAMATE DECARBOXYLASE 67; HUMAN MONOCLONAL ANTIBODY; HUMAN MONOCLONAL ANTIBODY B96.11; IMMUNOGLOBULIN F(AB) FRAGMENT; PHENYLALANINE; UNCLASSIFIED DRUG;

ANTIGENICITY; ARTICLE; CRYSTAL STRUCTURE; IN VITRO STUDY; MUTAGENESIS; PHAGE DISPLAY; PRIORITY JOURNAL; RADIOIMMUNOPRECIPITATION;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; AUTOIMMUNE DISEASES; EPITOPES; GLUTAMATE DECARBOXYLASE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; ISOENZYMES; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 33748790946     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2006.06.025     Document Type: Article

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