Mechanisms and models of cardiac excitation-contraction coupling

Lecture Notes in Mathematics

Volumn 1867, Issue , 2005, Pages 97-131

  Winslow, R L ^a   Hinch, R ^b   Greenstein, J L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33748771787     PISSN: 00758434     EISSN: None     Source Type: Book Series    
DOI: 10.1007/11406501_4     Document Type: Article

References (74)

1. Feske, S., Giltnane, J., Dolmetsch, R., Staudt, L.M. and Rao, A., Gene regulation mediated by calcium signals in T lymphocytes. Nat Immunol, 2001. 2: p. 316-24. 97
2. Lanahan, A. and Worley, P., Immediate-early genes and synaptic function. Neurobiol Learn Mem, 1998. 70(1-2): p. 37-43. 97
3. Cortassa, S., Aon, M., Marban, E., Winslow, R. and O'Rourke, B., An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophys. J., 2003. 84: p. 2734-2755. 97
4. Brette, F. and Orchard, C., T-tubule function in mammalian cardiac myocytes. Circ Res, 2003. 92(11): p. 1182-92. 98
5. Langer, G.A. and Peskoff, A., Calcium concentration and movement in the diadic cleft space of the cardiac ventricular cell. Biophys. J., 1996. 70: p. 1169-1182. 99, 107
6. Bers, D.M. and Perez-Reyes, E., Ca channels in cardiac myocytes: structure and function in Ca influx and intracellular Ca release. Cardiovasc Res, 1999. 42: p. 339-60. 99
7. Zhang, J.F., Ellinor, P.T., Aldrich, R.W. and Tsien, R.W., Molecular determinants of voltage-dependent inactivation in calcium channels. Nature, 1994. 372(6501): p. 97-100. 99
8. 2+ channel beta subunits revealed by their expression in adult rat heart cells. J Physiol, 2002. 541(Pt 2): p. 435-52. 99
9. Kamp, T.J. and Hell, J.W., Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res, 2000. 87(12): p. 1095-102. 100
10. 2+-dependent inactivation of L-type calcium channels. Neuron, 1999. 1999: p. 549-558. 100, 101
11. 2+ channels. Biophys. J., 2000. 78: p. 1906-1920. 100
12. Linz, K.W. and Meyer, R., Control of L-type calcium current during the action potential of guinea-pig ventricular myocytes. J Physiol (Lond), 1998. 513(Pt 2): p. 425-42. 101, 105, 106, 111
13. Lehnart, S.E., Wehrens, X.H., Kushnir, A. and Marks, A.R., Cardiac ryanodine receptor function and regulation in heart disease. Ann N Y Acad Sci, 2004. 1015: p. 144-59. 102
14. Marx, S.O., Gaburjakova, J., Gaburjakova, M., Henrikson, C., Ondrias, K. and Marks, A., Coupled gating between cardiac calcium release channels (ryanodine receptors). Circ. Res., 2001. 88: p. 1151-1158. 102, 119
15. Marx, S.O., Reiken, S., Hisamatsu, Y., Jayaraman, T., Burkhoff, D., Rosemblit, N. and Marks, A.R., PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell, 2000. 101: p. 365-76. 102
16. 2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). Circ Res, 2004. 94: p. 487-95. 102
17. 2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ Res, 2004. 94(6): p. e61-70. 102
18. Fabiato, A., Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J. Gen. Physiol., 1985. 85: p. 247-289. 102
19. Fabiato, A., Rapid ionic modifications during the aequorin-detected calcium transient in a skinned canine cardiac Purkinje cell. J Gen Physiol, 1985. 85: p. 189-246. 102
20. Fabiato, A., Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell. J Gen Physiol, 1985. 85: p. 291-320. 102
21. Wier, W.G., Egan, T.M., Lopez-Lopez, J.R. and Balke, C.W., Local control of excitation-contraction coupling in rat heart cells. J. Physiol., 474: p. 463-471. 102, 103, 107, 116
22. Bers, D. and Stiffel, V., Ratio of ryanodine to dihidropyridine receptors in cardiac and skeletal muscle and implications for E-C coupling. Am. J. Physiol., 1993. 264(6 Pt 1): p. C1587-C1593. 102
23. Langer, G.A., Myocardial Ion Transporters, in The Myocardium, G.A. Langer, Editor. 1997, Academic Press: San Diego, p. 143-179. 103
24. Blaustein, M.P. and Lederer, W.J., Sodium/calcium exchange: its physiological implications. Physiol Rev, 1999. 79: p. 763-854. 103
25. 2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes. J Physiol, 2000. 523 Pt 2: p. 339-51. 103
26. Kang, T.M., Markin, V.S. and Hilgemann, D.W., Ion fluxes in giant excised cardiac membrane patches detected and quantified with ion-selective microelectrodes. J Gen Physiol, 2003. 121: p. 325-47. 103
27. 2+ influx during the cardiac action potential in guinea pig ventricular myocytes. Circ. Res., 1996. 79: p. 194-200. 103
28. Shannon, T.R., Ginsburg, K.S. and Bers, D.M. Reverse mode of the SR, Ca, pump limits SR, Ca uptake in permeabilized and voltage clamped myocytes. in Cardiac Sarcoplasmic Reticulum Function and Regulation of Contractility. 1997. Washington, DC: New York Academy of Sciences. 104
29. Shannon, T.R., Ginsberg, K.S. and Bers, D.M., SR Ca uptake rate in permeabilized ventricular myocytes is limited by reverse rate of the SR Ca pump. Biophys. J., 1997. 72: p. A167. 104
30. Stern, M., Theory of excitation-contraction coupling in cardiac muscle. Biophys J, 1992. 63: p. 497-517. 104, 106, 107
31. 2+ dynamics: The roles of ryanodine receptor adaptation and sarcoplasmic reticulum load. Biophys. J., 1998. 74: p. 1149-1168. 104, 105, 106, 108, 113, 114
32. Winslow, R.L., Rice, J.J., Jafri, M.S., Marban, E. and O'Rourke, B., Mechanisms of Altered Excitation-Contraction Coupling in Canine TachycardiaInduced Heart Failure. II. Model Studies. Circ. Res., 1999. 84: p. 571-586. 104, 105, 106, 108, 122, 123
33. Noble, D., Varghese, A., Kohl, P. and Noble, P., Inproved Guinea-pig ventricular cell model incorporating a diadic space, Ikr and Iks. and length- and tension-dependent processes. Can. J. Cardiol., 1998. 14: p. 123-134. 104
34. Puglisi, J.L., Wang, F. and Bers, D.M., Modeling the isolated cardiac myocyte. Prog Biophys Mol Biol, 2004. 85(2-3): p. 163-78. 104
35. Faber, G.M. and Rudy, Y., Action potential and contractility changes in (i) overloaded cardiac myocytes: a simulation study. Biophys J, 2000. 78: p. 2392-404. 104
36. Luo, C.H. and Rudy, Y., A dynamic model of the cardiac ventricular action potential: I. Simulations of ionic currents and concentration changes. Circ Res, 1994. 74: p. 1071-1096. 104, 105, 106
37. Priebe, L. and Beuckelmann, D.J., Simulation study of cellular electric properties in heart failure. Circ Res, 1998. 82(11): p. 1206-23. 104
38. Rice, J.J., Jafri, M.S. and Winslow, R.L., Modeling short-term interval-force relations in cardiac muscle. Am J Physiol, 2000. 278: p. H913. 105
39. Iyer, V., Mazhari, R. and Winslow, R.L., A computational model of the human left-ventricular epicardial myocyte. Biophys. J., 2004. 87: p. in press. 105
40. 2+ signalling. J. Physiol., 1997. 500: p. 285-295. 107
41. Bers, D.M., Excitation Contraction Coupling and Cardiac Contractile Force. Series in Cardiovascular Medicine. Vol. 122. 1993, Boston: Kluwer Academic Press. 107
42. 2+ release units and couplons in skeletal and cardiac muscles. Biophys J, 1999. 77: p. 1528-39. 107, 109
43. 2+ release in the functional unit of the cardiac diadic space. Biophys J, 1999. 77: p. 1871-84. 107, 108
44. Soeller, C. and Cannell, M.B., Numerical simulation of local calcium movements during L-type calcium channel gating in the cardiac diad. Bipphys. J., 1997. 73: p. 97-111. 107
45. Cannell, M.B. and Soeller, C., Numerical analysis of ryanodine receptor activation by L-type channel activity in the cardiac muscle diad. Biophys. J., 1997. 73: p. 112-122. 107
46. Stern, M.D., Song, L.S., Cheng, H., Sham, J.S., Yang, H.T., Boheler, K.R. and Rios, E., Local control models of cardiac excitation-contraction coupling. A possible role for allosteric interactions between ryanodine receptors. J Gen Physiol, 1999. 113: p. 469-89. 107, 114
47. 2+ release. Biophys J, 2002. 83(6): p. 2918-45. 108, 110, 113, 115, 118, 119, 120
48. Mazhari, R., Greenstein, J.L., Winslow, R.L., Marban, E. and Nuss, H.B., Molecular interactions between two long-QT syndrome gene products, HERG and KCNES, rationalized by in vitro and in silica analysis. Circ Res, 2001. 89: p. 33-8. 108
49. Greenstein, J., Po, S., Wu, R., Tomaselli, G. and Winslow, R.L., Role of the calcium-independent transient outward current Itol in action potential morphology and duration. Circ. Res., 2000. 87: p. 1026. 108, 123
50. 2- sparks. Biophys J, 1998. 75: p. 595-600. 108
51. 2+ channels and ryanodine receptors in heart cells. Nature, 2001. 410(6828): p. 592-6. 108, 115, 119
52. 2+ release sites along Z-lines in rat heart cells. J Physiol (Lond), 1996. 497(Pt 1): p. 31-8. 108
53. 2+ spikes ' in rat cardiac myocytes. J Physiol, 1998. 512 (Pt 3): p. 677-91. 108
54. 2+ Release During Excitation-Contraction Coupling in Cardiac Myocytes. Circ Res, 2001. 88(8): p. 794-801. 109, 125
55. Matsumoto, M. and Nishimura, T., Mersenne twister: A 623-dimensionally equidistributed uniform pseudo-random number generator. ACMTMCS, 1998. 8: p. 3-30. 110
56. Hinch, R., Greenstein, J.L., Tanskanen, A.J. and Winslow, R.L., A simplified local control model of calcium induced calcium release in cardiac ventricular myocytes. Biophys. J., 2004. 87: p. 3723-3736. 112, 114
57. Hinch, R., A mathematical analysis of the generation and termination of calcium sparks. Biophys J, 2004. 86: p. 1293-307. 112, 113, 115
58. 2+ sparks: an investigative mathematical model of calcium-induced calcium release. Biophys J, 2002. 83: p. 59-78. 115
59. 2+ reserve. Circ Res, 2003. 93: p. 40-5. 115
60. Zahradnikova, A., Kubalova, Z., Pavelkova, J., Gyorke, S. and Zahradnik, I., Activation of calcium release assessed by calcium release-induced inactivation of calcium current in rat cardiac myocytes. Am J Physiol Cell Physiol, 2004. 286: p. C330-41. 117
61. + currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ. Res., 73: p. 379-385. 121
62. Kaab, S., Nuss, H.B., Chiamvimonvat, N., O'Rourke, B., Pak, P.H., Kass, D.A., Marban, E. and Tomaselli, G.F., Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circ Res, 1996. 78: p. 262-273. 121
63. Näbauer, M., Beuckelmann, D.J., Überfuhr, P. and Steinbeck, G., Regional differences in current density and rate-dependent properties of the transient outward current in subepicardial and subendocardial myocytes of human left ventricle. Circulation, 1996. 93: p. 168-177. 121
64. O'Rourke, B., Peng, L.F., Kaab, S., Tunin, R., Tomaselli, G.F., Kass, D.A. and Marban, E., Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart: Experimental studies. Circ. Res., 1999. 84: p. 562-570. 121
65. Winslow, R., Greenstein, J., Tomaselli, G. and O'Rourke, B., Computational model of the failing myocyte: Relating altered gene expression to cellular function. Phil. Trans. Roy. Soc. Lond. A, 2001. 359: p. 1187-1200. 123
66. Bers, D.M., Cardiac excitation-contraction coupling. Nature, 2002. 415(6868): p. 198-205. 99, 125
67. Greenstein, J.L., Tanskanen, A.J. and Winslow, R.L., Modeling the actions of b-adrenergic signaling on excitation-contraction coupling processes. Ann. N. Y. Acad. Sci., 2004. 1015: p. 16-27. 125, 126
68. Ginsburg, K.S., Weber, C.R. and Bers, D.M., Control of maximum sarcoplasmic reticulum Ca load in intact ferret ventricular myocytes. Effects of thapsigargin and isoproterenol J Gen Physiol, 1998. 111: p. 491-504. 125
69. 2+ release cascade by {beta}-adrenergic stimulation in rat ventricular myocytes. J Physiol (Lond), 2001. 533: p. 837-848. 125
70. Saucerman, J.J., Brunton, L.L., Michailova, A.P. and McCulloch, A.D., Modeling beta-adrenergic control of cardiac myocyte contractility in silica. J Biol Chem, 2003. 278(48): p. 47997-8003. 126
71. 2+ channel Cavl.2. Science, 2001. 293(5527): p. 98-101. 126
72. Hulme, J.T., Lin, T.W., Westenbroek, R.E., Scheuer, T. and Catterall, W.A., Beta-adrenergic regulation requires direct anchoring of PKA to cardiac CaV1.2 channels via a leucine zipper interaction with A kinase-anchoring protein 15. Proc Natl Acad Sci USA, 2003. 100(22): p. 13093-8. 126
73. Katz, A.M., Physiology of the Heart. Second ed. 1992, New York: Raven Press. 98
74. 2+ channel inactivation in controlling heart excitation. Proc Natl Acad Sci USA, 2002. 99(26): p. 17185-90. 124