The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat

European Journal of Pharmacology

Volumn 372, Issue 2, 1999, Pages 187-197

  Cuzzocrea, Salvatore ^a   Costantino, Giuseppina ^a   Zingarelli, Basilia ^a,b   Mazzon, Emanuela ^c   Micali, Antonio ^c   Caputi, Achille P ^a  

^a UNIVERSITY OF MESSINA   (Italy)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c NONE

Author keywords

Carrageenan; Glutathione; Hydroxyl radical; Inflammation; Nitric oxide (NO); Peroxynitrite; Superoxide

Indexed keywords

3 NITROTYROSINE; BUTHIONINE SULFOXIMINE; CARRAGEENAN; FLUORESCENT DYE; GLUTATHIONE; LUNG ENZYME; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NITRIC OXIDE SYNTHASE; PEROXYNITRITE; RHODAMINE 123; SCAVENGER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; EXUDATE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKOCYTE MIGRATION; LIPID PEROXIDATION; MACROPHAGE; MITOCHONDRIAL RESPIRATION; NEUTROPHIL; NONHUMAN; PLEURISY; PRIORITY JOURNAL; PROTECTION; RAT;

ANIMALS; CARRAGEENAN; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GLUTATHIONE; MACROPHAGES; NITRATES; NITRIC OXIDE; OXIDANTS; PLEURISY; PROTECTIVE AGENTS; RATS; TYROSINE;

EID: 0032971781     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(99)00200-9     Document Type: Article

References (45)

1. Alvarez B., Denicola A., Radi R. Reaction between peroxynitrite and hydrogen peroxide: formation of oxygen and slowing of peroxynitrite decomposition. Chem. Res. Toxicol. 8:1995;859-864.
2. Beckman J.S., Beckman T.W., Chen J., Marshall P.A., Freman B.A. Apparent hydroxyl radical production by peroxynitrite: implication for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. USA. 87:1990;1620-1624.
3. Berlett B.S., Friguet B., Yim M.B., Chock P.B., Stadtman E.R. Peroxynitrite-mediated nitration of tyrosine residues in Escherichia coli glutamine synthetase mimics adenylylation: relevance to signal transduction. Proc. Natl. Acad. Sci. USA. 93:1996;1776-1780.
4. Cuzzocrea S., Zingarelli B., Calapai G., Nava F., Caputi A.P. Zymosan-activated plasma induces paw oedema by nitric oxide and prostaglandin production. Life Sci. 60:1997;215-220.
5. Cuzzocrea S., Zingarelli B., Gilard E., Hake P., Salzman A.L., Szabó C. Protective effect of melatonin in carrageenan-induced models of local inflammation. J. Pineal Res. 23:1997;106-116.
6. Cuzzocrea S., Zingarelli B., Gilard E., Hake P., Salzman A.L., Szabó C. Anti-inflammatory effects of mercaptoethylguanidine, a combined inhibitor of nitric oxide synthase and peroxynitrite scavenger, in carrageenan-induced models of inflammation. Free Rad. Biol. Med. 24:1998;450-459.
7. Cuzzocrea S., Zingarelli B., Caputi A.P. Peroxynitrite-mediated DNA strand breakage activates poly (ADP-ribose) synthetase and causes cellular energy depletion in carrageenan-induced pleurisy. Immunology. 93:1998;9-101.
8. Cuzzocrea S., Zingarelli B., O'Connor M., Salzman A.L., Szabó C. Effect of L-Buthionine-(S,R)-Sulfoximide, an inhibitor of gamma-glutamylcysteine synthetase on the peroxynitrite and endotoxic shock-induced vascular failure. Br. J. Pharmacol. 123:1998;525-537.
9. Cuzzocrea S., Zingarelli B., Costantino G., Caputi A.P. Beneficial effects of Mn(III)tetrakis (4-benzoic acid) porphyrin (MnTBAP), a superoxide dismutase mimetic, in carrageenan-pleurisy Free Radic. Biol. Med. 26:1999;26-33.
10. Darley-Usmar V., Halliwell B. Reactive nitrogen species, reactive oxygen species, transition metal ions, and the vascular system. Pharm. Res. 13:1996;649-651. Blood radicals.
11. Eiserich J.P., Hristova M., Cross C.E., Jones A.D., Freeman B.A., Halliwell B., van der Vliet A. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature. 391:1998;393-397.
12. Gatti S., Faggioni R., Echtenacher B., Ghezzi P. Role of tumour necrosis factor and reactive oxygen intermediates in lipopolysaccharide-induced pulmonary oedema and lethality. Clin. Exp. Immunol. 91:1993;456-461.
13. Gow A.J., Duran D., Malcolm S., Ischiropoulos H. Effects of peroxynitrite-induced protein modifications on tyrosine phosphorylation and degradation. FEBS Lett. 385:1996;63-66.
14. Halliwell B. Oxygen radicals, nitrite oxide and human inflammatory joint disease. Ann. Rheum. Dis. 54:1995;505-510.
15. Heller B., Wang Z.Q., Wagner E.F., Radons J., Burkle A., Fehsel K., Burkart V., Kolb H. Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J. Biol. Chem. 270:1995;11176.
16. Ischiropoulos H., Zhu L., Chen J., Tsai M., Martin J.C., Smith C.D., Beckman J.S. Peroxynitrite-mediated tyrosine nitration catalysed by superoxide dismutase. Arch. Biochem. Biophys. 298:1992;431-437.
17. Karoui H., Hogg N., Frejaville C., Tordo P., Kalyanaraman B. Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite. ESR-spin trapping and oxygen uptake studies. J. Biol. Chem. 271:1996;6000-6009.
18. Laskin D.L., Heck D.E., Gardner C.R., Feder L.S., Laskin J.D. Distinct patterns of nitric oxide production in hepatic macrophages and endothelial cells following acute exposure of rats to endotoxin. J. Leukoc. Biol. 56:1994;751-758.
19. Lee K.J., Andrejuk T., Dziuban S.W. Jr., Goldfarb R.D. Deleterious effects of buthionine sulfoximine on cardiac function during continuous endotoxemia. Proc. Soc. Exp. Biol. Med. 209:1995;178-184.
20. Lombard-Gillooly K., Hubbard A.K. Modulation of silica-induced lung injury by reducing lung non-protein sulfhydryls with buthionine sulfoximine. Toxicol. Lett. 66:1993;305-315.
21. Martensson J., Steinherz R., Jain A., Meister A. Glutathione ester prevents buthionine sulfoximine-induced cataracts and lens epithelial cell damage. Proc. Natl. Acad Sci. USA. 86:1989;8727-8731.
22. McCord J. Oxygen-derived free radicals. New Horizons. 1:1993;70-76.
23. Meister A. On the antioxidant effects of ascorbic acid and glutathione. Biochem. Pharmacol. 44:1992;1905-1915.
24. Miles A.M., Bohle D.S., Glassbrenner P.A., Hansert B., Wink D.A., Grisham M.B. Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. J. Biol. Chem. 271:1996;40-47.
25. Mullane K.M., Kraemer R., Smith B. Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemic myocardium. J. Pharmacol. Meth. 14:1985;157-167.
26. Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB J. 6:1996;3051-3064.
27. Nemeth I., Boda D. The ratio of oxidized/reduced glutathione as an index of oxidative stress in various experimental models of shock syndrome. Biomed. Biochim. Acta. 48:1989;S53-S57.
28. Petit J.F., Nicaise M., Lepoivre M., Guissani A., Lemaire G. Protection by gluthatione against the antiproliferative effects of nitric oxide. Dependence on kinetics of no release. Biochem. Pharmacol. 52:1996;205-212.
29. Phelps D.T., Ferro T.J., Higgins P.J., Shankar R., Parker D.M., Johnson M. TNF-alpha induces peroxynitrite-mediated depletion of lung endothelial glutathione via protein kinase C. Am. J. Physiol. 269:1995;L551-L559.
30. Radi R., Beckman J.S., Bush K.M., Freeman B.A. Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266:1991;4244-4250.
31. Radi R., Rodriguez M., Castro L., Telleri R. Inhibition of mitochondrial electron transport by peroxynitrite. Arch. Biochem. Biophys. 308:1994;89-95.
32. Reddy V.N. Glutathione and its function in the lens - an overview. Exp. Eye Res. 50:1990;771-778.
33. Rubbo H., Radi R., Trujillo M., Telleri R., Kalyanaraman B., Barnes S., Kirk M., Freeman B.A. Nitric oxide regulation of superoxide and peroxynitrite-dependent lipid peroxidation. Formation of novel nitrogen-containing oxidized lipid derivatives. J. Biol. Chem. 269:1994;26066-26075.
34. Salvemini D., Wang Z.Q., Wyatt P., Bourdon D.M., Marino M.H., Manning P.T., Currie M.G. Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br. J. Pharmacol. 118:1996;829-838.
35. Schraufstatter I.U., Hinshaw D.B., Hyslop P.A., Spragg R.G., Cochrane C.G. Oxidant injury of cells: DNA strand-breaks activate polyadenosine diphosphate-ribose polymerase and lead to depletion of nicotinamide adenine dinucleotide. J. Clin. Invest. 77:1986;1312-1320.
36. Singh A., Lee K.J., Lee C.Y., Goldfarb R.D., Tsan M.F. Relation between myocardial glutathione content and extent of ischemia-reperfusion injury. Circulation. 80:1989;1795-1804.
37. Stein H.J., Hinder R.A., Oosthuizen M.M. Gastric mucosal injury caused by hemorrhagic shock and reperfusion: protective role of the antioxidant glutathione. Surgery. 108:1990;467-473.
38. Szabó C., Thiemermann C., Wu C.C., Perretti M., Vane J.R. Inhibition of nitric oxide synthase induction by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc. Natl. Acad Sci. USA. 91:1994;271-275.
39. Szabó C., Cuzzocrea S., Zingarelli B., O'Connor M., Salzman A.L. Endothelial dysfunction in endotoxic shock: importance of the activation of poly (ADP ribose synthetase (PARS) by peroxynitrite. J. Clin. Invest. 100:1997;723-735.
40. Van der Vliet A., Smith D., O'Neill C.A., Kaur H., Darley-Usmar V., Cross C.E., Halliwell B. Interactions of peroxynitrite with human plasma and its constituents: oxidative damage and antioxidant depletion. Biochem. J. 303:1994;295-301.
41. Villa L.M., Salas E., Darley-Usmar M., Radomski M.W., Moncada S. Peroxynitrite induces both vasodilatation and impaired vascular relaxation in the isolated perfused rat heart. Proc. Natl. Acad. Sci. USA. 91:1994;12383-12387.
42. Walker M.W., Kinter M.T., Roberts R.J., Spitz D.R. Nitric oxide-induced cytotoxicity: involvement of cellular resistance to oxidative stress and the role of glutathione in protection. Ped. Res. 37:1995;41-49.
43. Wei X.Q., Charles I.G., Smith A., Ure J., Feng G.J., Huang F.P., Xu D., Muller W., Moncada S., Liew F.Y. Altered immune responses in mice lacking inducible nitric oxide synthase. Nature. 375:1995;408-411.
44. Wiseman H., Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem. J. 313:1996;17-29.
45. Youn Y.K., Lalonde C., Demling R. Use of antioxidant therapy in shock and trauma. Circ. Shock. 35:1991;245-249.