메뉴 건너뛰기




Volumn 26, Issue 37, 2006, Pages 9482-9493

Expression of multiple P2X receptors by glossopharyngeal neurons projecting to rat carotid body O2-chemoreceptors: Role in nitric oxide-mediated efferent inhibition

Author keywords

ATP; CB chemoreceptors; Efferent inhibition; Glossopharyngeal neurons; Hypoxia; NO; P2X receptor

Indexed keywords

2 (4 CARBOXYPHENYL) 4,4,5,5 TETRAMETHYLIMIDAZOLINE 1 OXYL 3 OXIDE; 2',3' O (4 BENZOYLBENZOYL)ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE DERIVATIVE; CALCIUM; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; PURINE P2X RECEPTOR; PURINE P2X3 RECEPTOR; PURINE P2X4 RECEPTOR; PURINE P2X7 RECEPTOR; UNCLASSIFIED DRUG;

EID: 33748690769     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1672-06.2006     Document Type: Article
Times cited : (46)

References (53)
  • 2
    • 0028875979 scopus 로고
    • A P2X purinoceptor cDNA conferring a novel pharmacological profile
    • Bo X, Zhang Y, Nassar M, Burnstock G, Schoepfer R (1995) A P2X purinoceptor cDNA conferring a novel pharmacological profile. FEBS Lett 375:129-133.
    • (1995) FEBS Lett , vol.375 , pp. 129-133
    • Bo, X.1    Zhang, Y.2    Nassar, M.3    Burnstock, G.4    Schoepfer, R.5
  • 3
    • 0028025001 scopus 로고
    • New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
    • Brake AJ, Wagenbach MJ, Julius D (1994) New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor. Nature 371:519-523.
    • (1994) Nature , vol.371 , pp. 519-523
    • Brake, A.J.1    Wagenbach, M.J.2    Julius, D.3
  • 4
    • 0036118418 scopus 로고    scopus 로고
    • Purinergic signaling and vascular cell proliferation and death
    • Burnstock G (2002) Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol 22:364-373.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 364-373
    • Burnstock, G.1
  • 5
    • 4143056913 scopus 로고    scopus 로고
    • Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body
    • Buttigieg J, Nurse CA (2004) Detection of hypoxia-evoked ATP release from chemoreceptor cells of the rat carotid body. Biochem Biophys Res Commun 322:82-87.
    • (2004) Biochem Biophys Res Commun , vol.322 , pp. 82-87
    • Buttigieg, J.1    Nurse, C.A.2
  • 6
    • 15744396120 scopus 로고    scopus 로고
    • 2-sensitive neurons from the rat glossopharyngeal nerve
    • 2-sensitive neurons from the rat glossopharyngeal nerve. Neuroscience 132:437-451.
    • (2005) Neuroscience , vol.132 , pp. 437-451
    • Campanucci, V.A.1    Nurse, C.A.2
  • 9
    • 0142030089 scopus 로고    scopus 로고
    • Dehydroepiandrosterone potentiates native ionotropic ATP receptors containing the P2X2 subunit in rat sensory neurones
    • Lond
    • De Roo M, Rodeau JL, Schlichter R (2003) Dehydroepiandrosterone potentiates native ionotropic ATP receptors containing the P2X2 subunit in rat sensory neurones. J Physiol (Lond) 552:59-71.
    • (2003) J Physiol , vol.552 , pp. 59-71
    • De Roo, M.1    Rodeau, J.L.2    Schlichter, R.3
  • 12
    • 0034115430 scopus 로고    scopus 로고
    • The red blood cell as an oxygen sensor: What is the evidence?
    • Ellsworth ML (2000) The red blood cell as an oxygen sensor: what is the evidence? Acta Physiol Scand 168:551-559.
    • (2000) Acta Physiol Scand , vol.168 , pp. 551-559
    • Ellsworth, M.L.1
  • 13
    • 0029955763 scopus 로고    scopus 로고
    • Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells
    • Lond
    • Evans RJ, Lewis C, Virginio C, Lundstrom K, Buell G, Surprenant A, North RA (1996) Ionic permeability of, and divalent cation effects on, two ATP-gated cation channels (P2X receptors) expressed in mammalian cells. J Physiol (Lond) 497:413-422.
    • (1996) J Physiol , vol.497 , pp. 413-422
    • Evans, R.J.1    Lewis, C.2    Virginio, C.3    Lundstrom, K.4    Buell, G.5    Surprenant, A.6    North, R.A.7
  • 14
    • 0034808011 scopus 로고    scopus 로고
    • Acute hypoxia elevates nitric oxide generation in rat carotid body in vitro
    • Fung ML, Ye JS, Fung PC (2001) Acute hypoxia elevates nitric oxide generation in rat carotid body in vitro. Pflügers Arch 442:903-909.
    • (2001) Pflügers Arch , vol.442 , pp. 903-909
    • Fung, M.L.1    Ye, J.S.2    Fung, P.C.3
  • 16
    • 0028053910 scopus 로고
    • Carotid body chemoreceptors: From natural stimuli to sensory discharges
    • Gonzalez C, Almaraz L, Obeso A, Rigual R (1994) Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol Rev 74:829-898.
    • (1994) Physiol Rev , vol.74 , pp. 829-898
    • Gonzalez, C.1    Almaraz, L.2    Obeso, A.3    Rigual, R.4
  • 17
    • 0028153293 scopus 로고
    • Nitric oxide synthase occurs in neurons and nerve fibers of the carotid body
    • Grimes PA, Lahiri S, Stone R, Mokashi A, Chug D (1994) Nitric oxide synthase occurs in neurons and nerve fibers of the carotid body. Adv Exp Med Biol 360:221-224.
    • (1994) Adv Exp Med Biol , vol.360 , pp. 221-224
    • Grimes, P.A.1    Lahiri, S.2    Stone, R.3    Mokashi, A.4    Chug, D.5
  • 18
    • 33644819427 scopus 로고    scopus 로고
    • Effect of chronic hypoxia on purinergic synaptic transmission in rat carotid body
    • He L, Chen J, Dinger B, Stensaas L, Fidone S (2006) Effect of chronic hypoxia on purinergic synaptic transmission in rat carotid body. J Appl Physiol 100:157-162.
    • (2006) J Appl Physiol , vol.100 , pp. 157-162
    • He, L.1    Chen, J.2    Dinger, B.3    Stensaas, L.4    Fidone, S.5
  • 19
    • 0028286494 scopus 로고
    • Nitric oxide synthase in the rat carotid body and carotid sinus
    • Höhler B, Mayer B, Kummer W (1994) Nitric oxide synthase in the rat carotid body and carotid sinus. Cell Tissue Res 276:559-564.
    • (1994) Cell Tissue Res , vol.276 , pp. 559-564
    • Höhler, B.1    Mayer, B.2    Kummer, W.3
  • 21
    • 0035287474 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors and ATP signalling at synapses
    • Khakh BS (2001) Molecular physiology of P2X receptors and ATP signalling at synapses. Nat Rev Neurosci 2:165-174.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 165-174
    • Khakh, B.S.1
  • 23
    • 0035107660 scopus 로고    scopus 로고
    • International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits
    • Khakh BS, Burnstock G, Kennedy C, King BF, North RA, Seguela P, Voigt M, Humphrey PP (2001) International union of pharmacology. XXIV. Current status of the nomenclature and properties of P2X receptors and their subunits. Pharmacol Rev 53:107-118.
    • (2001) Pharmacol Rev , vol.53 , pp. 107-118
    • Khakh, B.S.1    Burnstock, G.2    Kennedy, C.3    King, B.F.4    North, R.A.5    Seguela, P.6    Voigt, M.7    Humphrey, P.P.8
  • 24
    • 0032529054 scopus 로고    scopus 로고
    • Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase
    • Lond
    • Kline DD, Yang T, Huang PL, Prabhakar NR (1998) Altered respiratory responses to hypoxia in mutant mice deficient in neuronal nitric oxide synthase. J Physiol (Lond) 511:273-287.
    • (1998) J Physiol , vol.511 , pp. 273-287
    • Kline, D.D.1    Yang, T.2    Huang, P.L.3    Prabhakar, N.R.4
  • 25
    • 0028982205 scopus 로고
    • Co-expression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons
    • Lewis C, Neidhart S, Holy C, North RA, Buell G, Surprenant A (1995) Co-expression of P2X2 and P2X3 receptor subunits can account for ATP-gated currents in sensory neurons. Nature 377:432-435.
    • (1995) Nature , vol.377 , pp. 432-435
    • Lewis, C.1    Neidhart, S.2    Holy, C.3    North, R.A.4    Buell, G.5    Surprenant, A.6
  • 27
    • 0019374051 scopus 로고
    • Location and size of carotid body-like organs (paraganglia) revealed in rats by the permeability of blood vessels to Evans blue dye
    • McDonald DM, Blewett RW (1981) Location and size of carotid body-like organs (paraganglia) revealed in rats by the permeability of blood vessels to Evans blue dye. J Neurocytol 10:607-643.
    • (1981) J Neurocytol , vol.10 , pp. 607-643
    • McDonald, D.M.1    Blewett, R.W.2
  • 29
    • 0027530024 scopus 로고
    • Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor
    • Murgia M, Hanau S, Pizzo P, Rippa M, Di Virgilio F (1993) Oxidized ATP. An irreversible inhibitor of the macrophage purinergic P2Z receptor. J Biol Chem 268:8199-8203.
    • (1993) J Biol Chem , vol.268 , pp. 8199-8203
    • Murgia, M.1    Hanau, S.2    Pizzo, P.3    Rippa, M.4    Di Virgilio, F.5
  • 30
    • 0036788971 scopus 로고    scopus 로고
    • Molecular physiology of P2X receptors
    • North RA (2002) Molecular physiology of P2X receptors. Physiol Rev 82:1013-1067.
    • (2002) Physiol Rev , vol.82 , pp. 1013-1067
    • North, R.A.1
  • 32
    • 21444434582 scopus 로고    scopus 로고
    • Neurotransmission and neuromodulation in the chemosensory carotid body
    • Nurse CA (2005) Neurotransmission and neuromodulation in the chemosensory carotid body. Auton Neurosci 120:1-9.
    • (2005) Auton Neurosci , vol.120 , pp. 1-9
    • Nurse, C.A.1
  • 33
    • 0032965831 scopus 로고    scopus 로고
    • Acetylcholine contributes to hypoxic chemotransmission in co-cultures of rat type 1 cells and petrosal neurons
    • Nurse CA, Zhang M (1999) Acetylcholine contributes to hypoxic chemotransmission in co-cultures of rat type 1 cells and petrosal neurons. Respir Physiol 115:189-199.
    • (1999) Respir Physiol , vol.115 , pp. 189-199
    • Nurse, C.A.1    Zhang, M.2
  • 34
    • 0032965968 scopus 로고    scopus 로고
    • NO and CO as second messengers in oxygen sensing in the carotid body
    • Prabhakar NR (1999) NO and CO as second messengers in oxygen sensing in the carotid body. Respir Physiol 115:161-168.
    • (1999) Respir Physiol , vol.115 , pp. 161-168
    • Prabhakar, N.R.1
  • 36
    • 0035893686 scopus 로고    scopus 로고
    • Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: Role in chemosensory signalling
    • Lond
    • Prasad M, Fearon IM, Zhang M, Laing M, Vollmer C, Nurse CA (2001) Expression of P2X2 and P2X3 receptor subunits in rat carotid body afferent neurones: role in chemosensory signalling. J Physiol (Lond) 537:667-677.
    • (2001) J Physiol , vol.537 , pp. 667-677
    • Prasad, M.1    Fearon, I.M.2    Zhang, M.3    Laing, M.4    Vollmer, C.5    Nurse, C.A.6
  • 38
    • 0031754497 scopus 로고    scopus 로고
    • Receptors for purines and pyrimidines
    • Ralevic V, Burnstock G (1998) Receptors for purines and pyrimidines. Pharmacol Rev 50:413-492.
    • (1998) Pharmacol Rev , vol.50 , pp. 413-492
    • Ralevic, V.1    Burnstock, G.2
  • 41
    • 0036129803 scopus 로고    scopus 로고
    • + channel activity in rat carotid body cells
    • + channel activity in rat carotid body cells. Pflügers Arch 443:671-675.
    • (2002) Pflügers Arch , vol.443 , pp. 671-675
    • Silva, J.M.1    Lewis, D.L.2
  • 43
    • 0033015343 scopus 로고    scopus 로고
    • 2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism
    • 2+ current in glomus cells of the rabbit carotid body via a cGMP-independent mechanism. J Neurophysiol 81:1449-1457.
    • (1999) J Neurophysiol , vol.81 , pp. 1449-1457
    • Summers, B.A.1    Overholt, J.L.2    Prabhakar, N.R.3
  • 44
    • 0028107625 scopus 로고
    • Nitric oxide: A radical neurotransmitter in the central nervous system
    • Vincent SR (1994) Nitric oxide: a radical neurotransmitter in the central nervous system. Prog Neurobiol 42:129-160.
    • (1994) Prog Neurobiol , vol.42 , pp. 129-160
    • Vincent, S.R.1
  • 45
    • 0027363419 scopus 로고
    • Neurons synthesizing nitric oxide innervate the mammalian carotid body
    • Wang ZZ, Bredt DS, Fidone SJ, Stensaas LJ (1993) Neurons synthesizing nitric oxide innervate the mammalian carotid body. J Comp Neurol 336:419-432.
    • (1993) J Comp Neurol , vol.336 , pp. 419-432
    • Wang, Z.Z.1    Bredt, D.S.2    Fidone, S.J.3    Stensaas, L.J.4
  • 48
    • 0028796381 scopus 로고
    • Nitric oxide mediates chemoreceptor inhibition in the cat carotid body
    • Wang ZZ, Stensaas LJ, Dinger BG, Fidone SJ (1995b) Nitric oxide mediates chemoreceptor inhibition in the cat carotid body. Neuroscience 65:217-229.
    • (1995) Neuroscience , vol.65 , pp. 217-229
    • Wang, Z.Z.1    Stensaas, L.J.2    Dinger, B.G.3    Fidone, S.J.4
  • 49
    • 15244346901 scopus 로고    scopus 로고
    • ATP inhibits the hypoxia response in type I cells of rat carotid bodies
    • Xu J, Xu F, Tse FW, Tse A (2005) ATP inhibits the hypoxia response in type I cells of rat carotid bodies. J Neurochem 92:1419-1430.
    • (2005) J Neurochem , vol.92 , pp. 1419-1430
    • Xu, J.1    Xu, F.2    Tse, F.W.3    Tse, A.4
  • 50
    • 0034725749 scopus 로고    scopus 로고
    • Does endogenous 5-HT mediate spontaneous rhythmic activity in chemoreceptor clusters of rat carotid body?
    • Zhang M, Nurse CA (2000) Does endogenous 5-HT mediate spontaneous rhythmic activity in chemoreceptor clusters of rat carotid body? Brain Res 872:199-203.
    • (2000) Brain Res , vol.872 , pp. 199-203
    • Zhang, M.1    Nurse, C.A.2
  • 51
    • 4143063659 scopus 로고    scopus 로고
    • 2/pH chemosensory signalling in co-cultures of rat carotid body receptors and petrosal neurons: Role of ATP and ACh
    • 2/pH chemosensory signalling in co-cultures of rat carotid body receptors and petrosal neurons: role of ATP and ACh. J Neurophysiol 92:3433-3445.
    • (2004) J Neurophysiol , vol.92 , pp. 3433-3445
    • Zhang, M.1    Nurse, C.A.2
  • 52
    • 0034658351 scopus 로고    scopus 로고
    • Co-release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors
    • Lond
    • Zhang M, Zhong H, Vollmer C, Nurse CA (2000) Co-release of ATP and ACh mediates hypoxic signalling at rat carotid body chemoreceptors. J Physiol (Lond) 525:143-158.
    • (2000) J Physiol , vol.525 , pp. 143-158
    • Zhang, M.1    Zhong, H.2    Vollmer, C.3    Nurse, C.A.4
  • 53
    • 0030660538 scopus 로고    scopus 로고
    • Synapse formation and hypoxic signalling in co-cultures of rat petrosal neurones and carotid body type 1 cells
    • Lond
    • Zhong H, Zhang M, Nurse CA (1997) Synapse formation and hypoxic signalling in co-cultures of rat petrosal neurones and carotid body type 1 cells. J Physiol (Lond) 503:599-612.
    • (1997) J Physiol , vol.503 , pp. 599-612
    • Zhong, H.1    Zhang, M.2    Nurse, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.