-
1
-
-
0033956237
-
Schizophrenia: Genes and environment
-
Tsuang MT (2000) Schizophrenia: genes and environment. Biol Psychiatry 47:210-220
-
(2000)
Biol Psychiatry
, vol.47
, pp. 210-220
-
-
Tsuang, M.T.1
-
2
-
-
0037308528
-
Genes for schizophrenia? Recent findings and their pathophysiological implications
-
Harrison PJ, Owen MJ (2003) Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 361:417-419
-
(2003)
Lancet
, vol.361
, pp. 417-419
-
-
Harrison, P.J.1
Owen, M.J.2
-
3
-
-
0029923725
-
Free radical pathology and antioxidant defense in schizophrenia: A review
-
Mahadik SP, Mukherjee S (1996) Free radical pathology and antioxidant defense in schizophrenia: a review. Schizophr Res 19:1-17
-
(1996)
Schizophr Res
, vol.19
, pp. 1-17
-
-
Mahadik, S.P.1
Mukherjee, S.2
-
4
-
-
0035133525
-
Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in different forms of schizophrenia
-
Herken H, Uz E, Ozyurt H, Sogut S, Virit O, Akyol O (2001) Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation are increased in different forms of schizophrenia. Mol Psychiatry 6:66-73
-
(2001)
Mol Psychiatry
, vol.6
, pp. 66-73
-
-
Herken, H.1
Uz, E.2
Ozyurt, H.3
Sogut, S.4
Virit, O.5
Akyol, O.6
-
5
-
-
0242667149
-
A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress
-
Marchbanks RM, Ryan M, Day I, Owen M, McGuffin P, Whatley S (2003) A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress. Schizophr Res 65:33-38
-
(2003)
Schizophr Res
, vol.65
, pp. 33-38
-
-
Marchbanks, R.M.1
Ryan, M.2
Day, I.3
Owen, M.4
McGuffin, P.5
Whatley, S.6
-
6
-
-
3142745187
-
Mitochondrial dysfunction in schizophrenia: Evidence for compromised brain metabolism and oxidative stress
-
Prabakaran S, Swatton J, Ryan M, Huffaker SJ, Huang JJ, Griffin JL, Wayland M, Freeman T, Dudbridge F, Lilley KS, Karp NA, Hester S, Tkachev D, Mimmack ML, Yolken RH, Webster MJ, Torrey EF, Bahn S (2004) Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress. Mol Psychiatry 9:684-697
-
(2004)
Mol Psychiatry
, vol.9
, pp. 684-697
-
-
Prabakaran, S.1
Swatton, J.2
Ryan, M.3
Huffaker, S.J.4
Huang, J.J.5
Griffin, J.L.6
Wayland, M.7
Freeman, T.8
Dudbridge, F.9
Lilley, K.S.10
Karp, N.A.11
Hester, S.12
Tkachev, D.13
Mimmack, M.L.14
Yolken, R.H.15
Webster, M.J.16
Torrey, E.F.17
Bahn, S.18
-
7
-
-
22444441576
-
Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts
-
Altar CA, Jurata LW, Charles V, Lemire A, Liu P, Bukhman Y, Young TA, Bullard J, Yokoe H, Webster MJ, Knable MB, Brockman JA (2005) Deficient hippocampal neuron expression of proteasome, ubiquitin, and mitochondrial genes in multiple schizophrenia cohorts. Biol Psychiatry 58:85-96
-
(2005)
Biol Psychiatry
, vol.58
, pp. 85-96
-
-
Altar, C.A.1
Jurata, L.W.2
Charles, V.3
Lemire, A.4
Liu, P.5
Bukhman, Y.6
Young, T.A.7
Bullard, J.8
Yokoe, H.9
Webster, M.J.10
Knable, M.B.11
Brockman, J.A.12
-
9
-
-
2342582130
-
NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia
-
Coyle JT, Tsai G (2004) NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia. Int Rev Neurobiol 59:491-515
-
(2004)
Int Rev Neurobiol
, vol.59
, pp. 491-515
-
-
Coyle, J.T.1
Tsai, G.2
-
11
-
-
0031723859
-
Role of endogenous glutathione in the oxidation of dopamine
-
Rabinovic AD, Hastings TG (1998) Role of endogenous glutathione in the oxidation of dopamine. J Neurochem 71:2071-2078
-
(1998)
J Neurochem
, vol.71
, pp. 2071-2078
-
-
Rabinovic, A.D.1
Hastings, T.G.2
-
12
-
-
0028339034
-
NMDA receptor channels: Subunit-specific potentiation by reducing agents
-
Kohr G, Eckardt S, Luddens H, Monyer H, Seeburg PH (1994) NMDA receptor channels: subunit-specific potentiation by reducing agents. Neuron 12:1031-1040
-
(1994)
Neuron
, vol.12
, pp. 1031-1040
-
-
Kohr, G.1
Eckardt, S.2
Luddens, H.3
Monyer, H.4
Seeburg, P.H.5
-
13
-
-
0033793205
-
Redox modulation of the NMDA receptor
-
Choi YB, Lipton SA (2000) Redox modulation of the NMDA receptor. Cell Mol Life Sci 57:1535-1541
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 1535-1541
-
-
Choi, Y.B.1
Lipton, S.A.2
-
14
-
-
0028971619
-
Gamma-glutamylglutamine and taurine concentrations are decreased in the cerebrospinal fluid of drug-naive patients with schizophrenic disorders
-
Do KQ, Lauer CJ, Schreiber W, Zollinger M, Gutteck-Amsler U, Cuenod M, Holsboer F (1995) Gamma-glutamylglutamine and taurine concentrations are decreased in the cerebrospinal fluid of drug-naive patients with schizophrenic disorders. J Neurochem 65:2652-2662
-
(1995)
J Neurochem
, vol.65
, pp. 2652-2662
-
-
Do, K.Q.1
Lauer, C.J.2
Schreiber, W.3
Zollinger, M.4
Gutteck-Amsler, U.5
Cuenod, M.6
Holsboer, F.7
-
15
-
-
0033787297
-
Schizophrenia: Glutathione deficit in cerebro spinal fluid and prefrontal cortex in vivo
-
Do KQ, Trebesinger A, Kirsten-Kruger M, Lauer C, Dydak U, Hell D, Holsboer F, Boesinger P, Cuenod M (2000) Schizophrenia: glutathione deficit in cerebro spinal fluid and prefrontal cortex in vivo. Eur J Neurosci 12:3721-3728
-
(2000)
Eur J Neurosci
, vol.12
, pp. 3721-3728
-
-
Do, K.Q.1
Trebesinger, A.2
Kirsten-Kruger, M.3
Lauer, C.4
Dydak, U.5
Hell, D.6
Holsboer, F.7
Boesinger, P.8
Cuenod, M.9
-
16
-
-
29244464827
-
Altered glutathione redox state in schizophrenia
-
Yao JK, Leonard S, Reddy R (2006) Altered glutathione redox state in schizophrenia. Dis Markers 22:83-93
-
(2006)
Dis Markers
, vol.22
, pp. 83-93
-
-
Yao, J.K.1
Leonard, S.2
Reddy, R.3
-
17
-
-
0037783987
-
Dopamine-induced oxidative stress in neurons with glutathione deficit: Implication for schizophrenia
-
Grima G, Benz B, Parpura V, Cuenod M, Do KQ (2003) Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia. Schizophr Res 62:213-224
-
(2003)
Schizophr Res
, vol.62
, pp. 213-224
-
-
Grima, G.1
Benz, B.2
Parpura, V.3
Cuenod, M.4
Do, K.Q.5
-
18
-
-
1642497596
-
Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: Relevance to schizophrenia
-
Castagne V, Rougemont M, Cuenod M, Do KQ (2004) Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: relevance to schizophrenia. Neurobiol Dis 15:93-105
-
(2004)
Neurobiol Dis
, vol.15
, pp. 93-105
-
-
Castagne, V.1
Rougemont, M.2
Cuenod, M.3
Do, K.Q.4
-
19
-
-
1642482417
-
An animal model with relevance to schizophrenia: Sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development
-
Castagne VV, Cuenod M, Do KQ (2004) An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development. Neuroscience 123:821-834
-
(2004)
Neuroscience
, vol.123
, pp. 821-834
-
-
Castagne, V.V.1
Cuenod, M.2
Do, K.Q.3
-
20
-
-
30144435733
-
Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: Relevance to schizophrenia
-
Steullet P, Neijt H, Cuenod M, Do KQ (2005) Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia. Neuroscience 137:807-819
-
(2005)
Neuroscience
, vol.137
, pp. 807-819
-
-
Steullet, P.1
Neijt, H.2
Cuenod, M.3
Do, K.Q.4
-
21
-
-
33744802393
-
Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: Relevance to schizophrenia
-
Cabungcal J, Nicolas D, Kraftsik R, Cuenod M, Do KQ, Hornung JP (2006) Glutathione deficit during development induces anomalies in the rat anterior cingulate GABAergic neurons: relevance to schizophrenia. Neurobiol Dis 22:624-637
-
(2006)
Neurobiol Dis
, vol.22
, pp. 624-637
-
-
Cabungcal, J.1
Nicolas, D.2
Kraftsik, R.3
Cuenod, M.4
Do, K.Q.5
Hornung, J.P.6
-
22
-
-
85030600852
-
Dysregulation of glutamate cysteine ligase in schizophrenia
-
Paper presented, Washington, DC, November 12-16
-
Gysin R, Tosic M, Chappuis C, Deppen P, Ruiz V, Bovet P, Cuenod M, Do KQ (2005) Dysregulation of glutamate cysteine ligase in schizophrenia. Paper presented at the 36th Annual Meeting of the Society for Neuroscience, Washington, DC, November 12-16
-
(2005)
36th Annual Meeting of the Society for Neuroscience
-
-
Gysin, R.1
Tosic, M.2
Chappuis, C.3
Deppen, P.4
Ruiz, V.5
Bovet, P.6
Cuenod, M.7
Do, K.Q.8
-
23
-
-
0027227925
-
Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase
-
Huang CS, Anderson ME, Meister A (1993) Amino acid sequence and function of the light subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem 268:20578-20583
-
(1993)
J Biol Chem
, vol.268
, pp. 20578-20583
-
-
Huang, C.S.1
Anderson, M.E.2
Meister, A.3
-
24
-
-
0027171195
-
Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase
-
Huang CS, Chang LS, Anderson ME, Meiste: A (1993) Catalytic and regulatory properties of the heavy subunit of rat kidney gamma-glutamylcysteine synthetase. J Biol Chem 268:19675-19680
-
(1993)
J Biol Chem
, vol.268
, pp. 19675-19680
-
-
Huang, C.S.1
Chang, L.S.2
Anderson, M.E.3
Meiste, A.4
-
25
-
-
0029591133
-
Mapping of the glutamate-cysteine ligase catalytic subunit gene (GLCLC) to human chromosome 6p12 and mouse chromosome 9D-E and of the regulatory subunit gene (GLCLR) to human chromosome 1p21-p22 and mouse chromosome 3H1-3
-
Tsuchiya K, Mulcahy RT, Reid LL, Disteche CM, Kavanagh TJ (1995) Mapping of the glutamate-cysteine ligase catalytic subunit gene (GLCLC) to human chromosome 6p12 and mouse chromosome 9D-E and of the regulatory subunit gene (GLCLR) to human chromosome 1p21-p22 and mouse chromosome 3H1-3. Genomics 30:630-632
-
(1995)
Genomics
, vol.30
, pp. 630-632
-
-
Tsuchiya, K.1
Mulcahy, R.T.2
Reid, L.L.3
Disteche, C.M.4
Kavanagh, T.J.5
-
27
-
-
0028134880
-
Diagnostic interview for genetic studies: Rationale, unique features, and training: NIMH Genetics Initiative
-
Nurnberger JI Jr, Blehar MC, Kaufmann CA, York-Cooler C, Simpson SG, Harkavy-Friedman J, Severe JB, Malaspina D, Reich T (1994) Diagnostic interview for genetic studies: rationale, unique features, and training: NIMH Genetics Initiative. Arch Gen Psychiatry 51:849-859
-
(1994)
Arch Gen Psychiatry
, vol.51
, pp. 849-859
-
-
Nurnberger Jr., J.I.1
Blehar, M.C.2
Kaufmann, C.A.3
York-Cooler, C.4
Simpson, S.G.5
Harkavy-Friedman, J.6
Severe, J.B.7
Malaspina, D.8
Reich, T.9
-
28
-
-
0037172653
-
Polymorphism in the 5′-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction
-
Nakamura S, Kugiyama K, Sugiyama S, Miyamoto S, Koide S, Fukushima H, Honda O, Yoshimura M, Ogawa H (2002) Polymorphism in the 5′-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction. Circulation 105:2968-2973
-
(2002)
Circulation
, vol.105
, pp. 2968-2973
-
-
Nakamura, S.1
Kugiyama, K.2
Sugiyama, S.3
Miyamoto, S.4
Koide, S.5
Fukushima, H.6
Honda, O.7
Yoshimura, M.8
Ogawa, H.9
-
29
-
-
0036594904
-
A strategy for the rapid discovery of disease markers using the MassARRAY system
-
Rodi CP, Darnhofer-Patel B, Stanssens P, Zabeau M, van den Boom D (2002) A strategy for the rapid discovery of disease markers using the MassARRAY system. Biotechniques 32:S62-S69
-
(2002)
Biotechniques
, vol.32
-
-
Rodi, C.P.1
Darnhofer-Patel, B.2
Stanssens, P.3
Zabeau, M.4
Van Den Boom, D.5
-
30
-
-
0033646792
-
Genetic heterogeneity in schizophrenia: Stratification of genome scan data using co-segregating related phenotypes
-
Pulver AE, Mulle J, Nestadt G, Swartz KL, Blouin JL, Dombroski B, Liang KY, Housman DE, Kazazian HH, Antonarakis SE, Lasseter VK, Wolyniec PS, Thornquist MH, McGrath JA (2000) Genetic heterogeneity in schizophrenia: stratification of genome scan data using co-segregating related phenotypes. Mol Psychiatry 5:650-653
-
(2000)
Mol Psychiatry
, vol.5
, pp. 650-653
-
-
Pulver, A.E.1
Mulle, J.2
Nestadt, G.3
Swartz, K.L.4
Blouin, J.L.5
Dombroski, B.6
Liang, K.Y.7
Housman, D.E.8
Kazazian, H.H.9
Antonarakis, S.E.10
Lasseter, V.K.11
Wolyniec, P.S.12
Thornquist, M.H.13
McGrath, J.A.14
-
31
-
-
28144444187
-
Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p
-
Arinami T, Ohtsuki T, Ishiguro H, Ujike H, Tanaka Y, Morita Y, Mineta M, et al (2005) Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet 77:937-944
-
(2005)
Am J Hum Genet
, vol.77
, pp. 937-944
-
-
Arinami, T.1
Ohtsuki, T.2
Ishiguro, H.3
Ujike, H.4
Tanaka, Y.5
Morita, Y.6
Mineta, M.7
-
32
-
-
0034803190
-
Glutathione S-transferase M1 gene deletion may be associated with susceptibility to certain forms of schizophrenia
-
Harada S, Tachikawa H, Kawanishi Y (2001) Glutathione S-transferase M1 gene deletion may be associated with susceptibility to certain forms of schizophrenia. Biochem Biophys Res Commun 281:267-271
-
(2001)
Biochem Biophys Res Commun
, vol.281
, pp. 267-271
-
-
Harada, S.1
Tachikawa, H.2
Kawanishi, Y.3
-
33
-
-
4644307783
-
Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population
-
Pae CU, Yu HS, Kim JJ, Kim W, Lee CU, Lee SJ, Jun TY, Lee C, Paik IH, Serretti A (2004) Glutathione S-transferase M1 polymorphism may contribute to schizophrenia in the Korean population. Psychiatr Genet 14:147-150
-
(2004)
Psychiatr Genet
, vol.14
, pp. 147-150
-
-
Pae, C.U.1
Yu, H.S.2
Kim, J.J.3
Kim, W.4
Lee, C.U.5
Lee, S.J.6
Jun, T.Y.7
Lee, C.8
Paik, I.H.9
Serretti, A.10
-
34
-
-
0037402528
-
Association study between glutathione S-transferase P1 polymorphism and schizophrenia in the Korean population
-
Pae CU, Kim JJ, Lee SJ, Lee CU, Lee C, Paik IH, Park HR, Yang S, Serretti A (2003) Association study between glutathione S-transferase P1 polymorphism and schizophrenia in the Korean population. Prog Neuropsychopharmacol Biol Psychiatry 27:519-523
-
(2003)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.27
, pp. 519-523
-
-
Pae, C.U.1
Kim, J.J.2
Lee, S.J.3
Lee, C.U.4
Lee, C.5
Paik, I.H.6
Park, H.R.7
Yang, S.8
Serretti, A.9
-
35
-
-
4644291562
-
No association between the Prol97Leu polymorphism in the glutathione peroxidase (GPX1) gene and schizophrenia
-
Shinkai T, Luca VD, Zai G, Shaikh S, Matsumoto C, Arnold PD, Hwang R, King N, Trakalo J, Potapova N, Wong G, Hori H, Wong AH, Ohmori O, Nakamura J, Kennedy JL (2004) No association between the Prol97Leu polymorphism in the glutathione peroxidase (GPX1) gene and schizophrenia. Psychiatr Genet 14:177-180
-
(2004)
Psychiatr Genet
, vol.14
, pp. 177-180
-
-
Shinkai, T.1
Luca, V.D.2
Zai, G.3
Shaikh, S.4
Matsumoto, C.5
Arnold, P.D.6
Hwang, R.7
King, N.8
Trakalo, J.9
Potapova, N.10
Wong, G.11
Hori, H.12
Wong, A.H.13
Ohmori, O.14
Nakamura, J.15
Kennedy, J.L.16
-
36
-
-
26644449682
-
Glutamate cysteine ligase catalysis: Dependence on ATP and modifier subunit for regulation of tissue glutathione levels
-
Chen Y, Shertzer HG, Schneider SN, Nebert DW, Dalton TP (2005) Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels. J Biol Chem 280:33766-33774
-
(2005)
J Biol Chem
, vol.280
, pp. 33766-33774
-
-
Chen, Y.1
Shertzer, H.G.2
Schneider, S.N.3
Nebert, D.W.4
Dalton, T.P.5
-
39
-
-
20044380772
-
Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia
-
Kolluri N, Sun Z, Sampson AR, Lewis DA (2005) Lamina-specific reductions in dendritic spine density in the prefrontal cortex of subjects with schizophrenia. Am J Psychiatry 162:1200-1202
-
(2005)
Am J Psychiatry
, vol.162
, pp. 1200-1202
-
-
Kolluri, N.1
Sun, Z.2
Sampson, A.R.3
Lewis, D.A.4
-
40
-
-
33744797200
-
Special bias deficit in rats with low glutathione during development: A behaviour model with relevance to schizophrenia
-
Cabungcal J, Singer D, Hornung J-P, Cuenod M, Do KQ, Schenk F (2004) Special bias deficit in rats with low glutathione during development: a behaviour model with relevance to schizophrenia. Schizophr Res 67 Suppl 1:118
-
(2004)
Schizophr Res
, vol.67
, Issue.SUPPL. 1
, pp. 118
-
-
Cabungcal, J.1
Singer, D.2
Hornung, J.-P.3
Cuenod, M.4
Do, K.Q.5
Schenk, F.6
-
41
-
-
0028323167
-
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
-
Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB Jr, Charney DS (1994) Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51:199-214
-
(1994)
Arch Gen Psychiatry
, vol.51
, pp. 199-214
-
-
Krystal, J.H.1
Karper, L.P.2
Seibyl, J.P.3
Freeman, G.K.4
Delaney, R.5
Bremner, J.D.6
Heninger, G.R.7
Bowers Jr., M.B.8
Charney, D.S.9
|