Altered glutathione redox state in schizophrenia

Disease Markers

Volumn 22, Issue 1-2, 2006, Pages 83-93

  Yao, Jeffrey K ^a,b,c   Leonard, Sherry ^d,e   Reddy, Ravinder ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d DENVER HEALTH AND HOSPITAL AUTHORITY   (United States)

^e UNIVERSITY OF COLORADO   (United States)

Author keywords

Age; Cigarette smoking; Glutathione; Glutathione disulfide; Glutathione peroxidase; Glutathione reductase; Postmortem caudate; Schizophrenia

Indexed keywords

ANTIOXIDANT; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; SCAVENGER;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; AUTOPSY; BRAIN TISSUE; CAUDATE NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ANALYSIS; ENZYME MECHANISM; FEMALE; HUMAN; HUMAN TISSUE; MALE; MEASUREMENT; MENTAL DISEASE; OXIDATION REDUCTION REACTION; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; REDUCTION; SCHIZOPHRENIA; STATISTICAL SIGNIFICANCE;

EID: 29244464827     PISSN: 02780240     EISSN: None     Source Type: Journal    
DOI: 10.1155/2006/248387     Document Type: Article

References (44)

1. H.J. Forman, J.M. Fukuto and M. Torres, Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers, Am J Physiol Cell Physiol 287 (2004), 246-256.
2. J.L. Cadet and J.B. Lohr, Free radicals and the developmental pathology of schizophrenic burnout, Integrative Psychiatry 5 (1987), 40-48.
3. S. Mukherjee, S.P. Mahadik, R. Scheffer, E.E. Correnti and H. Kelkar, Impaired antioxidant defense at the onset of psychosis, Schizophr Res 19 (1996), 19-26.
4. J.K. Yao, R.D. Reddy and D.P. van Kammen, Oxidative Damage and Schizophrenia: An Overview of the Evidence and Its Therapeutic Implications, CNS Drugs 15 (2001), 287-310.
5. J.K. Yao and P. Cheng, Determination of multiple redox-active compounds by high-performance liquid chromatography with coulometric multi-electrode array system, J. Chromatogr B810 (2004), 93-100.
6. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, (Fourth ed.), Washington, DC: American Psychiatric Association, 1994.
7. J.A. Hardy, P. Wester, B. Winblad, C. Gezelius, G. Bring and A. Eriksson, The patients dying after long terminal phase have acidotic brains; implications for biochemical measurements on autopsy tissue, J Neural Transm 61 (1985), 253-264.
8. P.J. Harrison, P.R. Heath, S.L. Eastwood, P.W.J. Burnet, B. McDonald and R.C.A. Pearson, The relative importance of premortem acidosis and postmortem interval for human brain gene expression studies: Selective mRNA vulnerability and comparison with their encoded proteins, Neuroscience Letters 200 (1995), 151-154.
9. P.E. Milbury, CEAS Generation of large multi-parameter metabolic databases for determining categorical process involvement of biological molecules, in: Progress in HPLC-HPCE, (Vol. 6), I.N. Acworth et al., eds, VSP International Science Publication, Utrecht, Holland, 1997, pp. 127-144.
10. B.S. Kristal, K. Vigneau-Callahan and W.R. Matson, Simultaneous analysis of multiple redox-active metabolites from biological matrices, in: Methods in Molecular Biology, (Vol. 186), Oxidative Stress Biomarkers and Antioxidant Protocols, D. Armstrong, ed., Humana Press Inc., Totowa, NJ, 2002, pp. 185-194.
11. H. Shi, K.E. Vigneau-Callahan, W.R. Matson and B.S. Kristal, Attention to relative response across sequential electrodes improves quantitation of coulometric array, Anal Biochem 302 (2002), 239-245.
12. A. Meister, Selective modification of glutathione metabolism, Science 220 (1983), 472-477.
13. E. Camera and M. Picardo, Analytical methods to investigate glutathione and related compounds in biological and pathological processes, J Chromatography B781 (2002), 181-206.
14. J. Lakritz, C.G. Plopper and A.R. Buckpitt, Validated high-performance liquid chromatography-electrochemical method for determination of glutathione and glutathione disulfide in small tissue samples, Anal Biochem 247 (1997), 63-68.
15. N.C. Smith, M. Dunnett and P.C. Mills, Simultaneous quantitation of oxidized and reduced glutathione in equine biological fluids by reverse-phase high-performance liquid chromatography using electrochemical detection, J Chromatogr B Biomed Appl 673 (1995), 35-41.
16. K.Q. Do, A.H. Trabesinger, M. Kirsten-Kruger, C.J. Lauer, U. Dydak, D. Hell, F. Holsboer, P. Boesiger and M. Cuenod, Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo, Eur J Neurosci 12 (2000), 3721-3728.
17. A. Meister, Mitochondrial changes associated with glutathione deficiency, Biochim Biophys Acta 1271 (1995), 35-42.
18. T.A. Seaton, P. Jenner and C.D. Marsden, Mitochondrial respiratory enzyme function and superoxide dismutase activity following brain glutathione depletion in the rat, Biochem Pharmacol 52 (1996), 1657-1663.
19. M.E. Anderson, Glutathione: an overview of biosynthesis and modulation, Chem Biol Interact 111-112 (1998), 1-14.
20. J. Navarro, E. Obrador, J.A. Pellicer, M. Aseni, J. Vina and J.M. Estrela, Blood glutathione as an index of radiation-induced oxidative stress in mice and humans, Free Radic Biol Med 22 (1997), 1203-1209.
21. N. Jha, O. Jurma, G. Lalli, Y. Liu, E.H. Petrus, J.T. Greenamyre, R.-M. Liu, H.J. Forman and J.K. Andersen, Glutathione Depletion in PC12 Results in Selective Inhibition of Mitochondrial Complex I Activity. IMPLICATIONS FOR PARKINSON'S DISEASE, J Biol Chem 275 (2000), 26096-26101.
22. J.D. Adams Jr, L.K. Klaidman, M.L. Chang and J. Yang, Brain oxidative stress - analytical chemistry and thermodynamics of glutathione and NADPH, Curr Top Med Chem 1 (2001), 473-482.
23. J. Keelan, N.J. Allen, D. Antcliffe, S. Pal and M.R. Duchen, Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane, J Neurosci Res 66 (2001), 873-884.
24. G. Grima, B. Benz, V. Parpura, M. Cuenod and K.Q. Do, Dopamine-induced oxidative stress in neurons with glutathione deficit: implication for schizophrenia, Schizophr Res 62 (2003), 213-224.
25. J.R. Hughes, D.K. Hatsukami, J.E. Mitchell and L.A. Dahlgren, Prevalence of smoking among psychiatric outpatients, Am J Psychiatry 143 (1986), 993-997.
26. J.B. Lohr and K. Flynn, Smoking and schizophrenia, Schizophr Res 8 (1992), 93-102.
27. A. Olincy, D.A. Young and R. Freedman, Increased levels of the nicotine metabolite cotinine in schizophrenic smokers compared to other smokers, Biol Psychiatry 42 (1997), 1-5.
28. D.F. Church and W.A. Pryor, Free radical chemistry of cigarette smoke and its toxicological implications, Environ Health Perpect 64 (1985), 111-126.
29. K.C. Chow, Vitamin E and cigarette smoking-induced oxidative damage, in: Vitamin E in Health and Disease, L. Packer and J. Fuchs, eds, Marcel Decker, New York, 1992, pp. 683-697.
30. W.A. Pryor and K. Stone, Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite, Ann N Y Acad Sci 686 (1993), 12-27.
31. B. Stegmayr, I. Johansson, F. Huhtasaari, U. Moser and K. Asplund, Use of smokeless tobacco and cigarettes - Effects on plasma levels of antioxidant vitamins, Int J Vitm Nutr Res 63 (1993), 195-200.
32. H. Nguyen, E. Finkelstein, A. Reznick, C. Cross and A. van der Vliet, Cigarette smoke impairs neutrophil respiratory burst activation by aldehyde-induced thiol modifications, Toxicology 160 (2001), 207-217.
33. I. Rahman and W. MacNee, Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease, Am J Physiol Lung Cell Mol Physiol 277 (1999), 1067-1088.
34. C. Piperi, A.E. Pouli, N.A. Katerelos, D.G. Hatzinikolaou, A. Stavridou and M.C. Psallidopoulos, Study of the mechanisms of cigarette smoke gas phase cytotoxicity, Anticancer Res 23 (2003), 2185-2190.
35. J. Nagy, E.G. Demaster, I. Wittmann, P. Shultz and L. Raij, Induction of endothelial cell injury by cigarette smoke, Endothelium 5 (1997), 251-263.
36. C. Rusznak, R.J. Sapsford, J.L. Devalia, R.J. John, E.L. Hewitt, A.G. Lamont, A.J. Wood, S.S. Shah, R.J. Davies and S. Lozewicz, Cigarette Smoke Potentiates House Dust Mite Allergen-Induced Increase in the Permeability of Human Bronchial Epithelial Cells In Vitro, Am J Respir Cell Mol Biol 20 (1999), 1238-1250.
37. C.E. Cross, C.A. O'Neill, A.Z. Reznick, M.L. Hu, L. Marcocci, L. Packer and B. Frei, Cigarette smoke oxidation of human plasma constituents, Ann NY Acad Sci 686 (1993), 72-89.
38. J.P. Eiserich, A. van der Vliet, G.J. Handelman, B. Halliwell and C.E. Cross, Dietary antioxidants and cigarette smoke-induced biomolecular damage: a complex interaction, Am J Clinical Nutrition 62 (1995), 1490-1500.
39. M.N. Hughes, Relationships between nitric oxide, nitroxyl ion, nitrosonium cation and peroxynitrite, Biochim Biophys Acta 1411 (1999), 263-272.
40. C. Quijano, B. Alvarez, R.M. Gatti, O. Augusto and R. Radi, Pathways of peroxynitrite oxidation of thiol groups, Biochem J 322 (1997), 167-173.
41. J.P. Bolanos, S.J. Heales, S. Peuchen, J.E. Barker, J.M. Land and J.B. Clark, Nitric oxide-mediated mitochondrial damage: a potential neuroprotective role for glutathione, Free Radic Biol Med 21 (1996), 995-1001.
42. V.G. Kharitonov, A.R. Sundquist and V.S. Sharma, Kinetics of nitrosation of thiols by nitric oxide in the presence of oxygen, J Biol Chem 270 (1995), 28158-28164.
43. S.J. Heales and J.P. Bolanos, Impairment of brain mitochondrial function by reactive nitrogen species: the role of glutathione in dictating susceptibility, Neurochem Int 40 (2002), 469-474.
44. J.K. Yao, S. Leonard and R.D. Reddy, Increased nitric oxide radicals in postmortem brain from patients with schizophrenia, Schizophr Bull 30 (2004), 923-934.