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Volumn 71, Issue 5, 1998, Pages 2071-2078

Role of endogenous glutathione in the oxidation of dopamine

Author keywords

Buthionine sulfoximine; Cysteinyl catechols; Oxidative stress; Parkinson's disease; Quinone; Reactive oxygen species

Indexed keywords

DOPAMINE; GLUTATHIONE;

EID: 0031723859     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1998.71052071.x     Document Type: Article
Times cited : (75)

References (59)
  • 1
    • 0029845402 scopus 로고    scopus 로고
    • Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons
    • Andersen J. K., Mo J. Q., Hom D. G., Lee F. Y., Harnish P., Hamill R. W., and McNeill T. H. (1996) Effect of buthionine sulfoximine, a synthesis inhibitor of the antioxidant glutathione, on the murine nigrostriatal neurons. J. Neurochem. 67, 2164-2171.
    • (1996) J. Neurochem. , vol.67 , pp. 2164-2171
    • Andersen, J.K.1    Mo, J.Q.2    Hom, D.G.3    Lee, F.Y.4    Harnish, P.5    Hamill, R.W.6    McNeill, T.H.7
  • 2
    • 0028127107 scopus 로고
    • Activation of microsomal glutathione S-transferase in tert-butyl hydroperoxide-induced oxidative stress of isolated rat liver
    • Aniya Y. and Daido A. (1994) Activation of microsomal glutathione S-transferase in tert-butyl hydroperoxide-induced oxidative stress of isolated rat liver. Jpn. J. Pharmacol. 66, 123-130.
    • (1994) Jpn. J. Pharmacol. , vol.66 , pp. 123-130
    • Aniya, Y.1    Daido, A.2
  • 3
    • 0028073654 scopus 로고
    • Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats
    • Awad J. A., Burk R. F., and Roberts L. J. II (1994) Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats. J. Pharmacol. Exp. Ther. 270, 858-864.
    • (1994) J. Pharmacol. Exp. Ther. , vol.270 , pp. 858-864
    • Awad, J.A.1    Burk, R.F.2    Roberts II, L.J.3
  • 4
    • 0014105888 scopus 로고
    • Enzyme-catalyzed conjugation of glutathione with unsaturated compounds
    • Boyland E. and Chasseaud L. F. (1966) Enzyme-catalyzed conjugation of glutathione with unsaturated compounds. Biochem. J. 104, 95-102.
    • (1966) Biochem. J. , vol.104 , pp. 95-102
    • Boyland, E.1    Chasseaud, L.F.2
  • 5
    • 0026671590 scopus 로고
    • The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats
    • Chan H. M., Tabarrok R., Tamura Y., and Cherian G. (1992) The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats. Chem. Biol. Interact. 84, 113-124.
    • (1992) Chem. Biol. Interact. , vol.84 , pp. 113-124
    • Chan, H.M.1    Tabarrok, R.2    Tamura, Y.3    Cherian, G.4
  • 6
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B., Sies H., and Boveris A. (1979) Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 59, 527-605.
    • (1979) Physiol. Rev. , vol.59 , pp. 527-605
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 7
    • 0016378870 scopus 로고
    • The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and other related cytotoxic agents
    • Cohen G. and Heikkila R. E. (1974) The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and other related cytotoxic agents. J. Biol. Chem. 249, 2447-2452.
    • (1974) J. Biol. Chem. , vol.249 , pp. 2447-2452
    • Cohen, G.1    Heikkila, R.E.2
  • 9
    • 0028124510 scopus 로고
    • Dopaminergic system activity and cellular defense mechanisms in the striatum and striatal synaptosomes of the rat subchronically exposed to manganese
    • Desole M. S., Misle M., Esposito G., Mighell R., Fresu L., De Natale G., and Miele E. (1994) Dopaminergic system activity and cellular defense mechanisms in the striatum and striatal synaptosomes of the rat subchronically exposed to manganese. Arch. Toxicol. 68, 566-570.
    • (1994) Arch. Toxicol. , vol.68 , pp. 566-570
    • Desole, M.S.1    Misle, M.2    Esposito, G.3    Mighell, R.4    Fresu, L.5    De Natale, G.6    Miele, E.7
  • 11
    • 0021671419 scopus 로고
    • Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes
    • Di Monte D., Ross D., Bellomo G., Eklöw L., and Orrenius S. (1984) Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch. Biochem. Biophys. 235, 334-342.
    • (1984) Arch. Biochem. Biophys. , vol.235 , pp. 334-342
    • Di Monte, D.1    Ross, D.2    Bellomo, G.3    Eklöw, L.4    Orrenius, S.5
  • 12
    • 0027990215 scopus 로고
    • Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death
    • Fernandes R. S. and Cotter T. G. (1994) Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death. Biochem. Pharmacol. 48, 675-681.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 675-681
    • Fernandes, R.S.1    Cotter, T.G.2
  • 13
    • 0027510177 scopus 로고
    • Pre- and postsynaptic neurotoxic effect of dopamine demonstrated by intrastriatal injection
    • Filloux F. and Townsend J. J. (1993) Pre-and postsynaptic neurotoxic effect of dopamine demonstrated by intrastriatal injection. Exp. Neurol. 119, 79-88.
    • (1993) Exp. Neurol. , vol.119 , pp. 79-88
    • Filloux, F.1    Townsend, J.J.2
  • 14
    • 0024556652 scopus 로고
    • A marked increase in 5-S-cysteinyl-dopamine in guinea-pig striatum following reserpine treatment
    • Fornstedt B. and Carlsson A. (1989) A marked increase in 5-S-cysteinyl-dopamine in guinea-pig striatum following reserpine treatment. J. Neural Transm. 76, 155-161.
    • (1989) J. Neural Transm. , vol.76 , pp. 155-161
    • Fornstedt, B.1    Carlsson, A.2
  • 15
    • 0026059789 scopus 로고
    • Vitamin C deficiency facilitated 5-S-cysteinyldopamine formation in guinea-pig striatum
    • Fornstedt B. and Carlsson A. (1991) Vitamin C deficiency facilitated 5-S-cysteinyldopamine formation in guinea-pig striatum. J. Neurochem. 56, 407-414.
    • (1991) J. Neurochem. , vol.56 , pp. 407-414
    • Fornstedt, B.1    Carlsson, A.2
  • 16
    • 0025014950 scopus 로고
    • An improved HPLC-electrochemical detection method for measuring brain levels of 5-S-cysteinyldopamine, 5-S-cysteinyl-3,4 dihydroxyphenylalanine, and 5-S-cysteinyl-3,4-dihydroxyphenylacetic acid
    • Fornstedt B., Bergh I., Rosengren E., and Carlsson A. (1990a) An improved HPLC-electrochemical detection method for measuring brain levels of 5-S-cysteinyldopamine, 5-S-cysteinyl-3,4 dihydroxyphenylalanine, and 5-S-cysteinyl-3,4-dihydroxyphenylacetic acid. J. Neurochem. 54, 578-586.
    • (1990) J. Neurochem. , vol.54 , pp. 578-586
    • Fornstedt, B.1    Bergh, I.2    Rosengren, E.3    Carlsson, A.4
  • 17
    • 0025472463 scopus 로고
    • In vivo autoxidation of dopamine in guinea-pig striatum increases with age
    • Fornstedt B., Pileblad E., and Carlsson A. (1990e) In vivo autoxidation of dopamine in guinea-pig striatum increases with age. J. Neurochem. 55, 655-659.
    • (1990) J. Neurochem. , vol.55 , pp. 655-659
    • Fornstedt, B.1    Pileblad, E.2    Carlsson, A.3
  • 18
    • 0023898945 scopus 로고
    • The relevance of Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • Gibbs W. R. G. and Lees A. J. (1988) The relevance of Lewy body to the pathogenesis of idiopathic Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 51, 745-752.
    • (1988) J. Neurol. Neurosurg. Psychiatry , vol.51 , pp. 745-752
    • Gibbs, W.R.G.1    Lees, A.J.2
  • 19
    • 0027937548 scopus 로고
    • Oxidative stress: Free radical production in neural degeneration
    • Götz M. E., Künig G., Riederer P., and Youdim M. B. H. (1994) Oxidative stress: free radical production in neural degeneration. Pharmacol. Ther. 63, 37-122.
    • (1994) Pharmacol. Ther. , vol.63 , pp. 37-122
    • Götz, M.E.1    Künig, G.2    Riederer, P.3    Youdim, M.B.H.4
  • 20
    • 0018095085 scopus 로고
    • Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones
    • Graham D. G. (1978) Oxidative pathways for catecholamines in the genesis of neuromelanin and cytotoxic quinones. Mol. Pharmacol. 14, 633-643.
    • (1978) Mol. Pharmacol. , vol.14 , pp. 633-643
    • Graham, D.G.1
  • 21
    • 0019167355 scopus 로고
    • Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine
    • Griffith O. W. (1980) Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal. Biochem. 106, 207-212.
    • (1980) Anal. Biochem. , vol.106 , pp. 207-212
    • Griffith, O.W.1
  • 22
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butylhomocysteine sulfoximine)
    • Griffith O. W. and Meister A. (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butylhomocysteine sulfoximine). J. Biol. Chem. 254, 7558-7560.
    • (1979) J. Biol. Chem. , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 23
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell B. (1992) Reactive oxygen species and the central nervous system. J. Neurochem. 59, 1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 24
    • 0030059868 scopus 로고    scopus 로고
    • L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress
    • Han S.-K., Mytilineou C., and Cohen G. (1996) L-DOPA up-regulates glutathione and protects mesencephalic cultures against oxidative stress. J. Neurochem. 66, 501-510.
    • (1996) J. Neurochem. , vol.66 , pp. 501-510
    • Han, S.-K.1    Mytilineou, C.2    Cohen, G.3
  • 25
    • 0028094864 scopus 로고
    • 3H]-dopamine: Impact of ascorbic acid and glutathione
    • 3H]-dopamine: impact of ascorbic acid and glutathione. J. Neurochem. 63, 1126-1132.
    • (1994) J. Neurochem. , vol.63 , pp. 1126-1132
    • Hastings, T.G.1    Zigmond, M.J.2
  • 26
    • 0029933450 scopus 로고    scopus 로고
    • Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections
    • Hastings T. G., Lewis D. A., and Zigmond M. J. (1996) Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections. Proc. Natl. Acad. Sci. USA 93, 1956-1961.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1956-1961
    • Hastings, T.G.1    Lewis, D.A.2    Zigmond, M.J.3
  • 27
    • 0017652854 scopus 로고
    • Chemilumincscence from 6-hydroxydopamine: Involvement of hydrogen peroxide, the superoxide radical and the hydroxyl radical, a potential role for singlet oxygen
    • Heikkila R. E. and Cabbat F. S. (1977) Chemilumincscence from 6-hydroxydopamine: involvement of hydrogen peroxide, the superoxide radical and the hydroxyl radical, a potential role for singlet oxygen. Res. Commun. Chem. Pathol. Pharmacol. 17, 649-662.
    • (1977) Res. Commun. Chem. Pathol. Pharmacol. , vol.17 , pp. 649-662
    • Heikkila, R.E.1    Cabbat, F.S.2
  • 28
    • 0013920522 scopus 로고
    • Dopamine (3-hydroxytyramine) and brain functions
    • Hornykiewicz O. (1966) Dopamine (3-hydroxytyramine) and brain functions. Pharmacol. Rev. 18, 925-964.
    • (1966) Pharmacol. Rev. , vol.18 , pp. 925-964
    • Hornykiewicz, O.1
  • 30
    • 0026740057 scopus 로고
    • New insights into the cause of Parkinson's disease
    • Jenner P., Schapira A. H. V., and Marsden C. D. (1992) New insights into the cause of Parkinson's disease. Neurology 42, 2241-2250.
    • (1992) Neurology , vol.42 , pp. 2241-2250
    • Jenner, P.1    Schapira, A.H.V.2    Marsden, C.D.3
  • 31
    • 0030775042 scopus 로고    scopus 로고
    • Decreased glutathione results in calcium-mediated cell death in PC12
    • Jurma O. P., Hom D. G., and Andersen J. K. (1997) Decreased glutathione results in calcium-mediated cell death in PC12. Free Radic. Biol. Med. 23, 1055-1066.
    • (1997) Free Radic. Biol. Med. , vol.23 , pp. 1055-1066
    • Jurma, O.P.1    Hom, D.G.2    Andersen, J.K.3
  • 32
    • 0022415447 scopus 로고
    • Glutathione peroxide activity in Parkinson's disease brain
    • Kish S. J., Morito C., and Hornykiewicz O. (1985) Glutathione peroxide activity in Parkinson's disease brain. Neurosci. Lett. 58, 343-346.
    • (1985) Neurosci. Lett. , vol.58 , pp. 343-346
    • Kish, S.J.1    Morito, C.2    Hornykiewicz, O.3
  • 33
    • 0018195287 scopus 로고
    • The glutathione status of cells
    • Kosower N. S. and Kosower E. M. (1978) The glutathione status of cells. Int. Rev. Cytol. 54, 109-160.
    • (1978) Int. Rev. Cytol. , vol.54 , pp. 109-160
    • Kosower, N.S.1    Kosower, E.M.2
  • 34
    • 0019350010 scopus 로고
    • Coupling of dopamine oxidation and monoamine oxidase activity to glutathione oxidation via the generation of hydrogen peroxide in rat brain homogenates
    • Maker H. S., Weiss C., Silides D. J., and Cohen G. (1981) Coupling of dopamine oxidation and monoamine oxidase activity to glutathione oxidation via the generation of hydrogen peroxide in rat brain homogenates. J. Neurochem. 36, 589-593.
    • (1981) J. Neurochem. , vol.36 , pp. 589-593
    • Maker, H.S.1    Weiss, C.2    Silides, D.J.3    Cohen, G.4
  • 35
    • 0002483781 scopus 로고
    • Biochemistry of glutathione
    • (Greenberg D. M., ed). Academic Press, New York
    • Meister A. (1975) Biochemistry of glutathione, in Metabolism of Sulfur Compounds (Greenberg D. M., ed). pp. 101-188. Academic Press, New York.
    • (1975) Metabolism of Sulfur Compounds , pp. 101-188
    • Meister, A.1
  • 36
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis and its reversal; applications in research and therapy
    • Meister A. (1991) Glutathione deficiency produced by inhibition of its synthesis and its reversal; applications in research and therapy. Pharmacol. Ther. 51, 155-194.
    • (1991) Pharmacol. Ther. , vol.51 , pp. 155-194
    • Meister, A.1
  • 37
    • 0028273316 scopus 로고
    • Glutathione, ascorbate and cellular protection
    • Meister A. (1994) Glutathione, ascorbate and cellular protection. Cancer Res. 54(Suppl.), 1969-1975.
    • (1994) Cancer Res. , vol.54 , Issue.SUPPL. , pp. 1969-1975
    • Meister, A.1
  • 38
    • 0029033862 scopus 로고
    • Mitochondrial changes associated with glutathione deficiency
    • Meister A. (1995) Mitochondrial changes associated with glutathione deficiency. Biochim. Biophys. Acta 127, 35-42.
    • (1995) Biochim. Biophys. Acta , vol.127 , pp. 35-42
    • Meister, A.1
  • 40
    • 0025063462 scopus 로고
    • Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture
    • Michel P. P. and Hefti F. (1990) Toxicity of 6-hydroxydopamine and dopamine for dopaminergic neurons in culture. J. Neurosci. Res. 26, 428-435.
    • (1990) J. Neurosci. Res. , vol.26 , pp. 428-435
    • Michel, P.P.1    Hefti, F.2
  • 41
    • 0030249286 scopus 로고    scopus 로고
    • Prevention of dopamine-induced cell death by thiol antioxidants: Possible implications for treatment of Parkinson's disease
    • Offen D., Ziv I., Sternin H., Melamed E., and Hochman A. (1996) Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease. Exp. Neurol. 141, 32-39.
    • (1996) Exp. Neurol. , vol.141 , pp. 32-39
    • Offen, D.1    Ziv, I.2    Sternin, H.3    Melamed, E.4    Hochman, A.5
  • 42
    • 0020308323 scopus 로고
    • Parkinson's disease: A disorder due to nigral glutathione deficiency?
    • Perry T. L., Godin D. V., and Hansen S. (1982) Parkinson's disease: a disorder due to nigral glutathione deficiency? Neurosci. Lett. 33, 305-310.
    • (1982) Neurosci. Lett. , vol.33 , pp. 305-310
    • Perry, T.L.1    Godin, D.V.2    Hansen, S.3
  • 43
    • 0025604179 scopus 로고
    • Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexene-1-one
    • Pileblad E. and Magnusson T. (1990) Effective depletion of glutathione in rat striatum and substantia nigra by L-buthionine sulfoximine in combination with 2-cyclohexene-1-one. Life Sci. 47, 2333-2342.
    • (1990) Life Sci. , vol.47 , pp. 2333-2342
    • Pileblad, E.1    Magnusson, T.2
  • 44
    • 0024537271 scopus 로고
    • Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum
    • Pileblad E., Magnusson T., and Fornstedt B. (1989) Reduction of brain glutathione by L-buthionine sulfoximine potentiates the dopamine-depleting action of 6-hydroxydopamine in rat striatum. J. Neurochem. 52, 978-980.
    • (1989) J. Neurochem. , vol.52 , pp. 978-980
    • Pileblad, E.1    Magnusson, T.2    Fornstedt, B.3
  • 45
    • 0010395844 scopus 로고    scopus 로고
    • Early indices of oxidative stress: Immediate response to neurotoxic levels of exogenous dopamine
    • Rabinovic A. D., Zigmond M. J., and Hastings T. G. (1996) Early indices of oxidative stress: immediate response to neurotoxic levels of exogenous dopamine. Soc. Neurosci. Abstr. 22, 221.
    • (1996) Soc. Neurosci. Abstr. , vol.22 , pp. 221
    • Rabinovic, A.D.1    Zigmond, M.J.2    Hastings, T.G.3
  • 47
    • 0023814368 scopus 로고
    • Catecholamine toxicity in cerebral cortex in dissociated cell culture
    • Rosenberg P.A. (1988) Catecholamine toxicity in cerebral cortex in dissociated cell culture. J. Neurosci. 8, 2887-2894.
    • (1988) J. Neurosci. , vol.8 , pp. 2887-2894
    • Rosenberg, P.A.1
  • 50
    • 0030582838 scopus 로고    scopus 로고
    • Mitochondrial respiratory enzyme function and superoxide dismutase activity following brain glutathione depletion in the rat
    • Seaton T. A., Jenner P., and Marsden C. D. (1996) Mitochondrial respiratory enzyme function and superoxide dismutase activity following brain glutathione depletion in the rat. Biochem. Pharmacol. 52, 1657-1663.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 1657-1663
    • Seaton, T.A.1    Jenner, P.2    Marsden, C.D.3
  • 51
    • 0028334997 scopus 로고
    • The role of thiols in mitochondrial susceptibility to iron and tert-butyl hydroperoxide-mediated toxicity in cultured mouse hepatocytes
    • Shertzer H. G., Bannenberg G. L., Zhu H., Liu R. M., and Moldeus P. (1994) The role of thiols in mitochondrial susceptibility to iron and tert-butyl hydroperoxide-mediated toxicity in cultured mouse hepatocytes. Chem. Res. Toxicol. 7, 358-366.
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 358-366
    • Shertzer, H.G.1    Bannenberg, G.L.2    Zhu, H.3    Liu, R.M.4    Moldeus, P.5
  • 53
    • 0026061854 scopus 로고
    • DOPA and dopamine cause cultured neuronal death in the presence of iron
    • Tanaka M., Sotomatsu A., Kanai H., and Hirai S. (1991) DOPA and dopamine cause cultured neuronal death in the presence of iron. J. Neurol. Sci. 101, 198-203.
    • (1991) J. Neurol. Sci. , vol.101 , pp. 198-203
    • Tanaka, M.1    Sotomatsu, A.2    Kanai, H.3    Hirai, S.4
  • 54
    • 0031025924 scopus 로고    scopus 로고
    • Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration
    • Toffa S., Kunikowska G. M., Zeng B.-Y., Jenner P., and Marsden C. D. (1997) Glutathione depletion in rat brain does not cause nigrostriatal pathway degeneration. J. Neural Transm. 104, 67-75.
    • (1997) J. Neural Transm. , vol.104 , pp. 67-75
    • Toffa, S.1    Kunikowska, G.M.2    Zeng, B.-Y.3    Jenner, P.4    Marsden, C.D.5
  • 55
    • 0026678026 scopus 로고
    • Characterization of the oxidative stress initiated in cultured human keratinocytes by treatment with peroxides
    • Vessey D. A., Lee K. H., and Blacker K. L. (1992) Characterization of the oxidative stress initiated in cultured human keratinocytes by treatment with peroxides. J. Invest. Dermatol. 99, 858-863.
    • (1992) J. Invest. Dermatol. , vol.99 , pp. 858-863
    • Vessey, D.A.1    Lee, K.H.2    Blacker, K.L.3
  • 56
    • 0022004746 scopus 로고
    • Nerve terminal damage in cerebral ischemia protective effect of alpha-methyl-O-para-tyrosine
    • Weinberger J., Nieves-Rosa J., and Cohen G. (1985) Nerve terminal damage in cerebral ischemia protective effect of alpha-methyl-O-para-tyrosine. Stroke 16, 864-870.
    • (1985) Stroke , vol.16 , pp. 864-870
    • Weinberger, J.1    Nieves-Rosa, J.2    Cohen, G.3
  • 58
    • 0028215392 scopus 로고
    • Effects of L-cysteine on the oxidation chemistry of dopamine: New reaction pathways of potential relevance to idiopathic Parkinson's disease
    • Zhang F. and Dryhurst G. (1994) Effects of L-cysteine on the oxidation chemistry of dopamine: new reaction pathways of potential relevance to idiopathic Parkinson's disease. J. Med. Chem. 37, 1084-1098.
    • (1994) J. Med. Chem. , vol.37 , pp. 1084-1098
    • Zhang, F.1    Dryhurst, G.2
  • 59
    • 0028198186 scopus 로고
    • Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons - A possible novel pathogenic mechanism in Parkinson's disease
    • Ziv I., Melamed E., Nardi N., Luria D., Achiron A., Offen D., and Barzilai A. (1994) Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons - a possible novel pathogenic mechanism in Parkinson's disease. Neurosci. Lett. 170, 136-140.
    • (1994) Neurosci. Lett. , vol.170 , pp. 136-140
    • Ziv, I.1    Melamed, E.2    Nardi, N.3    Luria, D.4    Achiron, A.5    Offen, D.6    Barzilai, A.7


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