Lithium leads to an increased FRQ protein stability and to a partial loss of temperature compensation in the Neurospora circadian clock

Journal of Biological Rhythms

Volumn 21, Issue 5, 2006, Pages 327-334

  Jolma, Ingunn W ^a   Falkeid, Grete ^a   Bamerni, Murad ^a   Ruoff, Peter ^a  

^a UNIVERSITY OF STAVANGER   (Norway)

Author keywords

Circadian rhythm; FRQ protein stability; Lithium; Neurospora crassa; Oscillatory feedback loops; Temperature compensation

Indexed keywords

FUNGAL PROTEIN; GLYCOGEN SYNTHASE KINASE 3; LEAD; LITHIUM; MAGNESIUM; PROTEASOME; PROTEIN FRQ; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; BIOLOGICAL RHYTHM; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENZYME ACTIVITY; FUNGUS GROWTH; NEUROSPORA; NONHUMAN; PERIODICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; TEMPERATURE ACCLIMATIZATION;

CIRCADIAN RHYTHM; FUNGAL PROTEINS; GLYCOGEN SYNTHASE KINASE 3; KINETICS; LITHIUM; MODELS, CHEMICAL; MODELS, STATISTICAL; NEUROSPORA CRASSA; OSCILLOMETRY; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; TEMPERATURE;

NEUROSPORA; NEUROSPORA CRASSA;

EID: 33748640133     PISSN: 07487304     EISSN: 15524531     Source Type: Journal    
DOI: 10.1177/0748730406292453     Document Type: Article

References (44)

1. Comolli J, Taylor W, and Hastings JW (1994) An inhibitor of protein phosphorylation stops the circadian oscillator and blocks light-induced phase shifting in Gonyaulax polyedra. J Biol Rhythms 9:13-26.
2. Comolli J, Taylor W, Rehman J, and Hastings JW (1996) Inhibitors of serine/threonine phosphoprotein phosphatases alter circadian properties in Gonyaulax polyedra. Plant Physiol 111:285-291.
3. Corey EJ and Li WD (1999) Total synthesis and biological activity of lactacystin, omuralide and analogs. Chem Pharm Bull (Tokyo) 47:1-10.
4. Dunlap JC and Feldman JF (1988) On the role of protein synthesis in the circadian clock of Neurospora crassa. Proc Natl Acad Sci U S A 85:1096-1100.
5. Dunlap JC and Loros JJ (2004) The Neurospora circadian system. J Biol Rhythms 19:414-424.
6. Dunlap JC, Loros JJ, and DeCoursey PJ (2004) Biological Timekeeping. Sunderland (UK): Sinauer Associates.
7. Dunlap JC, Taylor W, and Hastings JW (1980) The effects of protein synthesis inhibitors on the Gonyaulax clock. I. Phase-shifting effects of cycloheximide. J Comp Physiol 138:1-8.
8. Engelmann W (1987) Effects of lithium salts on circadian rhythms. In Chronobiology and Psychiatric Disorders, Halaris A, ed, pp 263-289. Amsterdam: Elsevier.
9. Feldman JF (1967) Lengthening the period of a biological clock in Euglena by cycloheximide, an inhibitor of protein synthesis. Proc Natl Acad Sci U S A 57:1080-1087.
10. Fenteany G and Schreiber SL (1998) Lactacystin, proteasome function, and cell fate. J Biol Chem 273:8545-8548.
11. Gardner GF and Feldman JF (1981) Temperature compensation of circadian periodicity in clock mutants of Neurospora crassa. Plant Physiol 68:1244-1248.
12. Goodenough JE, Bruce VG, and Carter A (1981) The effects of inhibitors affecting protein synthesis and membrane activity on the Chlamydomonas Reinhardii phototactic rhythm. Biol Bull 161:371-381.
13. Goodwin BC (1965) Oscillatory behavior in enzymatic control processes. Adv Enzyme Regul 3:425-438.
14. Gorl M, Merrow M, Huttner B, Johnson J, Roenneberg T, and Brunner M (2001) A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa. EMBO J 20:7074-7084.
15. He Q, Cheng P, and Liu Y (2005) The COP9 signalosome regulates the Neurospora circadian clock by controlling the stability of the SCFFWD-1 complex. Genes Dev 19:1518-1531.
16. He Q and Liu Y (2005) Degradation of the Neurospora circadian clock protein FREQUENCY through the ubiquitin-proteasome pathway. Biochem Soc Trans 33:953-956.
17. Iitaka C, Miyazaki K, Akaike T, and Ishida N (2005) A role for glycogen synthase kinase-3beta in the mammalian circadian clock. J Biol Chem 280:29397-29402.
18. Iwahana E, Akiyama M, Miyakawa K, Uchida A, Kasahara J, Fukunaga K, Hamada T, and Shibata S (2004) Effect of lithium on the circadian rhythms of locomotor activity and glycogen synthase kinase-3 protein expression in the mouse suprachiasmatic nuclei. Eur J Neurosci 19:2281-2287.
19. Jacklet JW (1980) Circadian rhythm from the eye of Aplysia: temperature compensation of the effects of protein synthesis inhibitors. J Exp Biol 84:1-15.
20. Johnsson A, Johnsen PI, Rinnan T, and Skrove D (1981) Basic properties of the circadian leaf movements of Oxalis regnellii, and period change due to lithium ions. Physiol Plant 53:361-367.
21. Johnsson A, Pflug B, Engelmann W, and Klemke W (1979) Effect of lithium carbonate on circadian periodicity in humans. Pharmakopsychiatr Neuropsychopharmakol 12:423-425.
22. Jonak C and Hirt H (2002) Glycogen synthase kinase 3/SHAGGY-like kinases in plants: an emerging family with novel functions. Trends Plant Sci 7:457-461.
23. Keck PE Jr (2004) Defining and improving response to treatment in patients with bipolar disorder. J Clin Psychiatry 65(Suppl 15):25-29.
24. Khalsa SB, Whitmore D, and Block GD (1992) Stopping the circadian pacemaker with inhibitors of protein synthesis. Proc Natl Acad Sci U S A 89:10862-10866.
25. Klein PS and Melton DA (1996) A molecular mechanism for the effect of lithium on development. Proc Natl Acad Sci U S A 93:8455-8459.
26. Lakin-Thomas PL (1993) Evidence against a direct role for inositol phosphate metabolism in the circadian oscillator and the blue-light signal transduction pathway in Neurospora crassa. Biochem J 292(Pt 3):813-818.
27. Liu Y Loros J, and Dunlap JC (2000) Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock. Proc Natl Acad Sci U S A 97:234-239.
28. Martinek S, Inonog S, Manoukian AS, and Young MW (2001) A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock. Cell 105: 769-779.
29. 2+ the underlying theme in the proposed mechanisms for the pharmacological action of lithium salts in bipolar disorder? Acc Chem Res 39:283-291.
30. Omura S, Fujimoto T, Otoguro K, Matsuzaki K, Moriguchi R, Tanaka H, and Sasaki Y (1991) Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells. J Antibiot (Tokyo) 44:113-116.
31. Padiath QS, Paranjpe D, Jain S, and Sharma VK (2004) Glycogen synthase kinase 3beta as a likely target for the action of lithium on circadian clocks. Chronobiol Int 21:43-55.
32. Pittendrigh CS and Caldarola PC (1973) General homeostasis of the frequency of circadian oscillations. Proc Natl Acad Sci U S A 70:2697-2701.
33. Pittendrigh CS, Caldarola PC, and Cosbey ES (1973) A differential effect of heavy water on temperature-dependent and temperature-compensated aspects of circadian system of Drosophila pseudoobscura. Proc Natl Acad Sci U S A 70:2037-2041.
34. Rice AM and Sartorelli AC (2001) Inhibition of 20 S and 26 S proteasome activity by lithium chloride: impact on the differentiation of leukemia cells by all-trans retinoic acid. J Biol Chem 276:42722-42727.
35. Roenneberg T, Nakamura H, and Hastings JW (1988) Creatine accelerates the circadian clock in a unicellular alga. Nature 334:432-434.
36. Ruoff P, Behzadi A, Hauglid M, Vinsjevik M, and Havas H (2000) pH homeostasis of the circadian sporulation rhythm in clock mutants of Neurospora crassa. Chronobiol Int 17:733-750.
37. Ruoff P, Loros JJ, and Dunlap JC (2005) The relationship between FRQ-protein stability and temperature compensation in the Neurospora circadian clock. Proc Natl Acad Sci U S A 102:17681-17686.
38. Ruoff P, Vinsjevik M, Mohsenzadeh S, and Rensing L (1999) The Goodwin model: simulating the effect of cycloheximide and heat shock on the sporulation rhythm of Neurospora crassa. J Theor Biol 196:483-494.
39. Ryves WJ and Harwood AJ (2001) Lithium inhibits glycogen synthase kinase-3 by competition for magnesium. Biochem Biophys Res Commun 280:720-725.
40. Taylor WR, Dunlap JC, and Hastings JW (1982) Inhibitors of protein synthesis on 80S ribosomes phase shift the Gonyaulax clock. J Exp Biol 97:121-136.
41. Vogel HA (1956) A convenient growth medium for Neurospora (medium N). Microbiol Gen Bull 15:42-43.
42. Yang Y, Cheng P, He Q, Wang L, and Liu Y (2003) Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock. Mol Cell Biol 23:6221-6228.
43. Yang Y, He Q, Cheng P, Wrage P, Yarden O, and Liu Y (2004) Distinct roles for PP1 and PP2A in the Neurospora circadian clock. Genes Dev 18:255-260.
44. Yin L, Wang J, Klein PS, and Lazar MA (2006) Nuclear receptor Rev-erbα is a critical lithium-sensitive component of the circadian clock. Science 311:1002-1005.