Abnormal prion accumulation associated with retinal pathology in experimentally inoculated scrapie-affected sheep

Veterinary Pathology

Volumn 43, Issue 5, 2006, Pages 733-739

  Greenlee, J J ^a   Hamir, A N ^a   West Greenlee, M H ^b  

^a NATIONAL ANIMAL DISEASE CENTER   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Glial fibrillary acidic protein; Immunohistochemistry; Prion diseases; Retina; Scrapie; Sheep; Spongiform encephalopathy

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; GLIA; METABOLISM; PATHOLOGY; PRION; RETINA; RETINA DISEASE; SCRAPIE; SHEEP; UPREGULATION;

ANIMALS; GLIAL FIBRILLARY ACIDIC PROTEIN; NEUROGLIA; PRIONS; RETINA; RETINAL DISEASES; SCRAPIE; SHEEP; UP-REGULATION;

OVIS ARIES;

EID: 33748593902     PISSN: 03009858     EISSN: 03009858     Source Type: Journal    
DOI: 10.1354/vp.43-5-733     Document Type: Article

References (33)

1. Askanas V, Bilak M, Engel WK, Leclerc A, Tome F: Prion protein is strongly immunolocalized at the postsynaptic domain of human normal neuromuscular junctions. Neurosci Lett 159:111-114, 1993
2. Barnett KC, Palmer AC: Retinopathy in sheep affected with natural scrapie. Res Vet Sci 12:383-385, 1971
3. Bons N, Lehmann S, Mestre-Frances N, Dormont D, Brown P: Brain and buffy coat transmission of bovine spongiform encephalopathy to the primate Microcebus murinus. Transfusion 42:513-516, 2002
4. Bradley R: BSE transmission studies with particular reference to blood. Dev Biol Stand 99:35-40, 1999
5. Buyukmihci N, Goehring-Harmon F, Marsh RF: Retinal degeneration during clinical scrapie encephalopathy in hamsters. J Comp Neurol 205:153-160, 1982
6. Buyukmihci N, Rorvik M, Marsh RF: Replication of the scrapie agent in ocular neural tissues. Proc Natl Acad Sci U S A 77:1169-1171, 1980
7. c) is expressed in photoreceptor cells of the adult retina. Neurosci Lett 234:11-14, 1997
8. Sc propagation in experimental and natural scrapie in sheep with different PrP genotypes. Vet Pathol 42:258-274, 2005
9. Foster J, Farquhar C, Fraser J, Somerville R: Immunolocalization of the prion protein in scrapie affected rodent retinas. Neurosci Lett 260:1-4, 1999
10. Foster JD, Davies DJ, Fraser H: Primary retinopathy in scrapie in mice deprived of light. Neurosci Lett 72:111-114, 1986
11. Foster JD, Fraser H, Bruce ME: Retinopathy in mice with experimental scrapie. Neuropathol Appl Neurobiol 12:185-196, 1986
12. Hamir AN, Kunkle RA, Miller JM, Richt JA: Second passage of sheep scrapie and transmissable mink encephalopathy (TME) agents in raccoons (Procyon lotor). Vet Pathol 42:844-851, 2005
13. Hamir AN, Kunkle RA, Richt JA, Miller JM, Cutlip RC, Jenny AL: Experimental transmission of sheep scrapie by intracerebral and oral routes to genetically susceptible Suffolk sheep in the United States. J Vet Diagn Invest 17:3-9, 2005
14. Hamir AN, Miller JM, Cutlip RC, Kunkle RA, Jenny AL, Stack MJ, Chaplin MJ, Richt JA: Transmission of sheep scrapie to elk (Cervus elaphus nelsoni) by intracerebral inoculation: final outcome of the experiment. J Vet Diagn Invest 16:316-321, 2004
15. Hardt M, Baron T, Groschup MH: A comparative study of immunohistochemical methods for detecting abnormal prion protein with monoclonal and polyclonal antibodies. J Comp Pathol 122:43-53, 2000
16. Head MW, Northcott V, Rennison K, Ritchie D, McCardle L, Bunn TJ, McLennan NF, Ironside JW, Tullo AB, Bonshek RE: Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease. Invest Ophthalmol Vis Sci 44:342-346, 2003
17. Head MW, Peden AH, Yull HM, Ritchie DL, Bonshek RE, Tullo AB, Ironside JW: Abnormal prion protein in the retina of the most commonly occurring subtype of sporadic Creutzfeldt-Jakob disease. Br J Ophthalmol 89:1131-1133, 2005
18. Herms J, Tings T, Gall S, Madlung A, Giese A, Siebert H, Schurmann P, Windl O, Brose N, Kretzschmar H: Evidence of presynaptic location and function of the prion protein. J Neurosci 19:8866-8875, 1999
19. Hogan RN, Baringer JR, Prusiner SB: Progressive retinal degeneration in scrapie-infected hamsters: a light and electron microscopic analysis. Lab Invest 44:34-42, 1981
20. Hogan RN, Bowman KA, Baringer JR, Prusiner SB: Replication of scrapie prions in hamster eyes precedes retinal degeneration. Ophthalmic Res 18:230-235, 1986
21. Hong DH, Pawlyk BS, Adamian M, Sandberg MA, Li T: A single, abbreviated RPGR-ORF15 variant reconstitutes RPGR function in vivo. Invest Ophthalmol Vis Sci 46:435-441, 2005
22. Jeffrey M, Martin S, Thomson JR, Dingwall WS, Begara-McGorum I, Gonzalez L: Onset and distribution of tissue PrP accumulation in scrapie-affected Suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies. J Comp Pathol 125:48-57, 2001
23. Kercher L, Favara C, Chan CC, Race R, Chesebro B: Differences in scrapie-induced pathology of the retina and brain in transgenic mice that express hamster prion protein in neurons, astrocytes, or multiple cell types. Am J Pathol 165:2055-2067, 2004
24. Lewis GP, Fisher SK: Up-regulation of glial fibrillary acidic protein in response to retinal injury: its potential role in glial remodeling and a comparison to vimentin expression. Int Rev Cytol 230:263-290, 2003
25. Marella M, Chabry J: Neurons and astrocytes respond to prion infection by inducing microglia recruitment. J Neurosci 24:620-627, 2004
26. Moya KL, Sales N, Hassig R, Creminon C, Grassi J, Di Giamberardino L: Immunolocalization of the cellular prion protein in normal brain. Microsc Res Tech 50:58-65, 2000
27. O'Rourke KI, Baszler TV, Miller JM, Spraker TR, Sadler-Riggleman I, Knowles DP: Monoclonal antibody F89/160.1.5 defines a conserved epitope on the ruminant prion protein. J Clin Microbiol 36:1750-1755, 1998
28. Russelakis-Carneiro M, Betmouni S, Perry VH: Inflammatory response and retinal ganglion cell degeneration following intraocular injection of ME7. Neuropathol Appl Neurobiol 25:196-206, 1999
29. Russelakis-Carneiro M, Hetz C, Maundrell K, Soto C: Prion replication alters the distribution of synaptophysin and caveolin 1 in neuronal lipid rafts. Am J Pathol 165:1839-1848, 2004
30. Spraker TR, O'Rourke KI, Balachandran A, Zink RR, Cummings BA, Miller MW, Powers BE: Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (Odocoileus hemionus) with chronic wasting disease. J Vet Diagn Invest 14:3-7, 2002
31. Spraker TR, Zink RR, Cummings BA, Wild MA, Miller MW, O'Rourke KI: Comparison of histological lesions and immunohistochemical staining of proteinase-resistant prion protein in a naturally occurring spongiform encephalopathy of free-ranging mule deer (Odocoileus hemionus) with those of chronic wasting disease of captive mule deer. Vet Pathol 39:110-119, 2002
32. Valdez RA, Rock MJ, Anderson AK, O'Rourke KI: Immunohistochemical detection and distribution of prion protein in a goat with natural scrapie. J Vet Diagn Invest 15:157-162, 2003
33. Wu KH, Madigan MC, Billson FA, Penfold PL: Differential expression of GFAP in early v late AMD: A quantitative analysis. Br J Ophthalmol 87:1159-1166, 2003