Computational analysis of the mode of binding of 8-oxoguanine to formamidopyrimidine-DNA glycosylase

Biochemistry

Volumn 45, Issue 36, 2006, Pages 10886-10894

  Song, Kun ^a   Hornak, Viktor ^a   De Los Santos, Carlos ^a   Grollman, Arthur P ^a   Simmerling, Carlos ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTATIONAL METHODS; CRYSTALLOGRAPHY; DNA; ESCHERICHIA COLI; MOLECULAR STRUCTURE; STABILIZATION;

8-OXOGUANINE (8OG); ANTI CONFORMATION; BACILLUS STEAROTHERMOPHILUS; COMPUTATIONAL ANALYSIS;

GENETIC ENGINEERING;

8 HYDROXYGUANINE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; DOUBLE STRANDED DNA; GUANINE; MUTANT PROTEIN; PROTEIN DERIVATIVE; PROTEIN E77; SERINE; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CRYSTAL STRUCTURE; DNA DAMAGE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME STABILITY; ESCHERICHIA COLI; EXCISION REPAIR; GEOBACILLUS STEAROTHERMOPHILUS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SIMULATION;

AMINO ACID SEQUENCE; BACILLUS STEAROTHERMOPHILUS; BINDING SITES; COMPUTER SIMULATION; CONSERVED SEQUENCE; DNA REPAIR; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; GUANINE; MODELS, MOLECULAR; MUTATION; PROTEIN CONFORMATION;

ESCHERICHIA COLI; GEOBACILLUS STEAROTHERMOPHILUS;

EID: 33748508626     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060380m     Document Type: Article

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