Nutritional Disorders in the Elderly

Medical Clinics of North America

Volumn 90, Issue 5, 2006, Pages 887-907

  Chapman, Ian McPhee ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ANOREXIA; APPETITE; BODY COMPOSITION; BODY WEIGHT; ELDERLY CARE; FOOD INTAKE; HUMAN; MALNUTRITION; NUTRITIONAL DISORDER; PRIORITY JOURNAL; PROTEIN CALORIE MALNUTRITION; REVIEW; WEIGHT REDUCTION;

AGED; ANOREXIA; AVITAMINOSIS; BODY COMPOSITION; CAUSALITY; CROSS-SECTIONAL STUDIES; EATING DISORDERS; FEMALE; HUMANS; HYPOCALCEMIA; MALE; OBESITY; PROTEIN-ENERGY MALNUTRITION; RISK FACTORS; WEIGHT LOSS;

EID: 33748482165     PISSN: 00257125     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcna.2006.05.010     Document Type: Review

References (98)

1. Wurtman J.J., Lieberman H., Tsay R., et al. Calorie and nutrient intakes of elderly and young subjects measured under identical conditions. J Gerontol 43 6 (1988) B174-B180
2. Clarkston W.K., Pantano M.M., Morley J.E., et al. Evidence for the anorexia of aging: gastrointestinal transit and hunger in healthy elderly vs. young adults. Am J Physiol 272 1 Pt 2 (1997) R243-R248
3. Morley J.E. Anorexia of aging: physiologic and pathologic. Am J Clin Nutr 66 4 (1997) 760-773
4. Villareal D.T., Apovian C.M., Kushner R.F., et al. Obesity in older adults: technical review and position statement of the American Society for Nutrition and NAASO, The Obesity Society. Am J Clin Nutr 82 5 (2005) 923-934
5. Wallace J.I., Schwartz R.S., LaCroix A.Z., et al. Involuntary weight loss in older outpatients: incidence and clinical significance. J Am Geriatr Soc 43 4 (1995) 329-337
6. Newman A.B., Arnold A.M., Burke G.L., et al. Cardiovascular disease and mortality in older adults with small abdominal aortic aneurysms detected by ultrasonography: The Cardiovascular Health Study. Ann Intern Med 134 3 (2001) 182-190
7. Prentice A.M., and Jebb S.A. Beyond body mass index. Obes Rev 2 3 (2001) 141-147
8. Beaufrere B., and Morio B. Fat and protein redistribution with aging: metabolic considerations. Eur J Clin Nutr 54 Suppl 3 (2000) S48-S53
9. Cree M.G., Newcomer B.R., Katsanos C.S., et al. Intramuscular and liver triglycerides are increased in the elderly. J Clin Endocrinol Metab 89 8 (2004) 3864-3871
10. Campbell A.J., Spears G.F., Brown J.S., et al. Anthropometric measurements as predictors of mortality in a community population aged 70 years and over. Age Ageing 19 2 (1990) 131-135
11. Morley J.E., and Silver A.J. Nutritional issues in nursing home care. Ann Intern Med 123 11 (1995) 850-859
12. Cederholm T., Jagren C., and Hellstrom K. Outcome of protein-energy malnutrition in elderly medical patients. Am J Med 98 1 (1995) 67-74
13. Sullivan D.H., Walls R.C., and Lipschitz D.A. Protein-energy undernutrition and the risk of mortality within 1 y of hospital discharge in a select population of geriatric rehabilitation patients. Am J Clin Nutr 53 3 (1991) 599-605
14. Manson J.E., Willett W.C., Stampfer M.J., et al. Body weight and mortality among women. N Engl J Med 333 11 (1995) 677-685
15. Calle E.E., Thun M.J., Petrelli J.M., et al. Body-mass index and mortality in a prospective cohort of US adults. N Engl J Med 341 15 (1999) 1097-1105
16. Somes G.W., Kritchevsky S.B., Shorr R.I., et al. Body mass index, weight change, and death in older adults: the systolic hypertension in the elderly program. Am J Epidemiol 156 2 (2002) 132-138
17. Heiat A., Vaccarino V., and Krumholz H.M. An evidence-based assessment of federal guidelines for overweight and obesity as they apply to elderly persons. Arch Intern Med 161 9 (2001) 1194-1203
18. Omran M.L., and Morley J.E. Assessment of protein energy malnutrition in older persons, Part II: laboratory evaluation. Nutrition 16 2 (2000) 131-140
19. Potter J.F., Schafer D.F., and Bohi R.L. In-hospital mortality as a function of body mass index: an age-dependent variable. J Gerontol 43 3 (1988) M59-M63
20. Rumpel C., Harris T.B., and Madans J. Modification of the relationship between the Quetelet index and mortality by weight-loss history among older women. Ann Epidemiol 3 4 (1993) 343-350
21. Melton III L.J., Khosla S., and Riggs B.L. Epidemiology of sarcopenia. Mayo Clin Proc 75 Suppl (2000) S10-S12 [discussion S12-3]
22. Janssen I., Baumgartner R.N., Ross R., et al. Skeletal muscle cutpoints associated with elevated physical disability risk in older men and women. Am J Epidemiol 159 4 (2004) 413-421
23. Roberts S.B., Fuss P., Heyman M.B., et al. Control of food intake in older men. JAMA 272 20 (1994) 1601-1606
24. Doty R.L., Shaman P., Applebaum S.L., et al. Smell identification ability: changes with age. Science 226 4681 (1984) 1441-1443
25. Yeh S.S., and Schuster M.W. Geriatric cachexia: the role of cytokines. Am J Clin Nutr 70 2 (1999) 183-197
26. Roubenoff R., Harris T.B., Abad L.W., et al. Monocyte cytokine production in an elderly population: effect of age and inflammation. J Gerontol A Biol Sci Med Sci 53 1 (1998) M20-M26
27. Toth M.J., Matthews D.E., Tracy R.P., et al. Age-related differences in skeletal muscle protein synthesis: relation to markers of immune activation. Am J Physiol Endocrinol Metab 288 5 (2005) E883-E891
28. Payette H., Roubenoff R., Jacques P.F., et al. Insulin-like growth factor-1 and interleukin 6 predict sarcopenia in very old community-living men and women: The Framingham Heart Study. J Am Geriatr Soc 51 9 (2003) 1237-1243
29. Roubenoff R., Parise H., Payette H.A., et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: The Framingham Heart Study. Am J Med 115 6 (2003) 429-435
30. Walker D., and Beauchene R.E. The relationship of loneliness, social isolation, and physical health to dietary adequacy of independently living elderly. J Am Diet Assoc 91 3 (1991) 300-304
31. Evers M.M., and Marin D.B. Mood disorders. Effective management of major depressive disorder in the geriatric patient. Geriatrics 57 10 (2002) 36-40 [quiz 41]
32. Morley J.E., and Kraenzle D. Causes of weight loss in a community nursing home. J Am Geriatr Soc 42 6 (1994) 583-585
33. Wilson M.M., Vaswani S., Liu D., et al. Prevalence and causes of undernutrition in medical outpatients. Am J Med 104 1 (1998) 56-63
34. Morris M.S., Fava M., Jacques P.F., et al. Depression and folate status in the US population. Psychother Psychosom 72 2 (2003) 80-87
35. Thomas P., Hazif-Thomas C., and Clement J.P. Influence of antidepressant therapies on weight and appetite in the elderly. J Nutr Health Aging 7 3 (2003) 166-170
36. Sahyoun N.R., Otradovec C.L., Hartz S.C., et al. Dietary intakes and biochemical indicators of nutritional status in an elderly, institutionalized population. Am J Clin Nutr 47 3 (1988) 524-533
37. Fuhrman M.P., Charney P., and Mueller C.M. Hepatic proteins and nutrition assessment. J Am Diet Assoc 104 8 (2004) 1258-1264
38. Guigoz Y., Lauque S., and Vellas B.J. Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment. Clin Geriatr Med 18 4 (2002) 737-757
39. Ribaudo J.M., Cella D., Hahn E.A., et al. Re-validation and shortening of the Functional Assessment of Anorexia/Cachexia Therapy (FAACT) questionnaire. Qual Life Res 9 10 (2000) 1137-1146
40. Keller H.H., McKenzie J.D., and Goy R.E. Construct validation and test-retest reliability of the seniors in the community: risk evaluation for eating and nutrition questionnaire. J Gerontol A Biol Sci Med Sci 56 9 (2001) M552-M558
41. Wilson M.M., Thomas D.R., Rubenstein L.Z., et al. Appetite assessment: simple appetite questionnaire predicts weight loss in community-dwelling adults and nursing home residents. Am J Clin Nutr 82 5 (2005) 1074-1081
42. Milne A.C., Avenell A., and Potter J. Meta-analysis: protein and energy supplementation in older people. Ann Intern Med 144 1 (2006) 37-48
43. Milne A.C., Potter J., and Avenell A. Protein and energy supplementation in elderly people at risk from malnutrition. Cochrane Database Syst Rev 2 (2005) CD003288
44. Manders M., de Groot L.C., van Staveren W.A., et al. Effectiveness of nutritional supplements on cognitive functioning in elderly persons: a systematic review. J Gerontol A Biol Sci Med Sci 59 10 (2004) 1041-1049
45. Wilson M.M., Purushothaman R., and Morley J.E. Effect of liquid dietary supplements on energy intake in the elderly. Am J Clin Nutr 75 5 (2002) 944-947
46. Morley J.E. Orexigenic and anabolic agents. Clin Geriatr Med 18 4 (2002) 853-866
47. Yeh S.S., Wu S.Y., Lee T.P., et al. Improvement in quality-of-life measures and stimulation of weight gain after treatment with megestrol acetate oral suspension in geriatric cachexia: results of a double-blind, placebo-controlled study. J Am Geriatr Soc 48 5 (2000) 485-492
48. Volicer L., Stelly M., Morris J., et al. Effects of dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease. Int J Geriatr Psychiatry 12 9 (1997) 913-919
49. Flegal K.M., Carroll M.D., Ogden C.L., et al. Prevalence and trends in obesity among US adults, 1999-2000. JAMA 288 14 (2002) 1723-1727
50. Mokdad A.H., Bowman B.A., Ford E.S., et al. The continuing epidemics of obesity and diabetes in the United States. JAMA 286 10 (2001) 1195-1200
51. Flegal K.M., Graubard B.I., Williamson D.F., et al. Excess deaths associated with underweight, overweight, and obesity. JAMA 293 15 (2005) 1861-1867
52. Cicuttini F.M., and Spector T.D. Osteoarthritis in the aged. Epidemiological issues and optimal management. Drugs Aging 6 5 (1995) 409-420
53. Cicuttini F.M., Baker J.R., and Spector T.D. The association of obesity with osteoarthritis of the hand and knee in women: a twin study. J Rheumatol 23 7 (1996) 1221-1226
54. Jensen G.L. Obesity and functional decline: epidemiology and geriatric consequences. Clin Geriatr Med 21 4 (2005) 677-687
55. Fine J.T., Colditz G.A., Coakley E.H., et al. A prospective study of weight change and health-related quality of life in women. JAMA 282 22 (1999) 2136-2142
56. Schott A.M., Cormier C., Hans D., et al. How hip and whole-body bone mineral density predict hip fracture in elderly women: the EPIDOS Prospective Study. Osteoporos Int 8 3 (1998) 247-254
57. Ensrud K.E., Fullman R.L., Barrett-Connor E., et al. Voluntary weight reduction in older men increases hip bone loss: the osteoporotic fractures in men study. J Clin Endocrinol Metab 90 4 (2005) 1998-2004
58. Langlois J.A., Harris T., Looker A.C., et al. Weight change between age 50 years and old age is associated with risk of hip fracture in white women aged 67 years and older. Arch Intern Med 156 9 (1996) 989-994
59. Yaari S., and Goldbourt U. Voluntary and involuntary weight loss: associations with long term mortality in 9,228 middle-aged and elderly men. Am J Epidemiol 148 6 (1998) 546-555
60. Wannamethee S.G., Shaper A.G., and Lennon L. Reasons for intentional weight loss, unintentional weight loss, and mortality in older men. Arch Intern Med 165 9 (2005) 1035-1040
61. Gregg E.W., Gerzoff R.B., Thompson T.J., et al. Intentional weight loss and death in overweight and obese US adults 35 years of age and older. Ann Intern Med 138 5 (2003) 383-389
62. Fontaine K.R., and Allison D.B. Does intentional weight loss affect mortality rate?. Eat Behav 2 2 (2001) 87-95
63. Wing R.R., Hamman R.F., Bray G.A., et al. Achieving weight and activity goals among diabetes prevention program lifestyle participants. Obes Res 12 9 (2004) 1426-1434
64. Garrow J.S., and Summerbell C.D. Meta-analysis: effect of exercise, with or without dieting, on the body composition of overweight subjects. Eur J Clin Nutr 49 1 (1995) 1-10
65. Ryan A.S., Nicklas B.J., and Dennis K.E. Aerobic exercise maintains regional bone mineral density during weight loss in postmenopausal women. J Appl Physiol 84 4 (1998) 1305-1310
66. Binder E.F., Schechtman K.B., Ehsani A.A., et al. Effects of exercise training on frailty in community-dwelling older adults: results of a randomized, controlled trial. J Am Geriatr Soc 50 12 (2002) 1921-1928
67. Seguin R., and Nelson M.E. The benefits of strength training for older adults. Am J Prev Med 25 3 (2003) (Suppl 2):141-9
68. Chang J.T., Morton S.C., Rubenstein L.Z., et al. Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomised clinical trials. BMJ 328 7441 (2004) 680
69. Calvo M.S., Whiting S.J., and Barton C.N. Vitamin D fortification in the United States and Canada: current status and data needs. Am J Clin Nutr 80 6 Suppl (2004) 1710S-1716S
70. Bischoff-Ferrari H.A., Dietrich T., Orav E.J., et al. Higher 25-hydroxyvitamin D concentrations are associated with better lower-extremity function in both active and inactive persons aged > or = 60 y. Am J Clin Nutr 80 3 (2004) 752-758
71. Flicker L., MacInnis R.J., Stein M.S., et al. Should older people in residential care receive vitamin D to prevent falls? Results of a randomized trial. J Am Geriatr Soc 53 11 (2005) 1881-1888
72. Chapuy M.C., Arlot M.E., Duboeuf F., et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med 327 23 (1992) 1637-1642
73. Dawson-Hughes B., Harris S.S., Krall E.A., et al. Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age or older. N Engl J Med 337 10 (1997) 670-676
74. Need A.G., O'Loughlin P.D., Morris H.A., et al. The effects of age and other variables on serum parathyroid hormone in postmenopausal women attending an osteoporosis center. J Clin Endocrinol Metab 89 4 (2004) 1646-1649
75. Hanley D.A., and Davison K.S. Vitamin D insufficiency in North America. J Nutr 135 2 (2005) 332-337
76. MacLaughlin J., and Holick M.F. Aging decreases the capacity of human skin to produce vitamin D3. J Clin Invest 76 4 (1985) 1536-1538
77. Need A.G., Morris H.A., Horowitz M., et al. Effects of skin thickness, age, body fat, and sunlight on serum 25-hydroxyvitamin D. Am J Clin Nutr 58 6 (1993) 882-885
78. Calvo M.S., Whiting S.J., and Barton C.N. Vitamin D intake: a global perspective of current status. J Nutr 135 2 (2005) 310-316
79. Gaugris S., Heaney R.P., Boonen S., et al. Vitamin D inadequacy among post-menopausal women: a systematic review. QJM 98 9 (2005) 667-676
80. McKenna M.J. Differences in vitamin D status between countries in young adults and the elderly. Am J Med 93 1 (1992) 69-77
81. Reid I.R., Ames R.W., Evans M.C., et al. Long-term effects of calcium supplementation on bone loss and fractures in postmenopausal women: a randomized controlled trial. Am J Med 98 4 (1995) 331-335
82. Grant A.M., Avenell A., Campbell M.K., et al. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomised placebo-controlled trial. Lancet 365 9471 (2005) 1621-1628
83. Ervin R.B., and Kennedy-Stephenson J. Mineral intakes of elderly adult supplement and non-supplement users in the third National Health and Nutrition Examination Survey. J Nutr 132 11 (2002) 3422-3427
84. Bonaa K.H., Njolstad I., Ueland P.M., et al. Homocysteine lowering and cardiovascular events after acute myocardial infarction. N Engl J Med 354 4 (2006) 1578-1588
85. Lindenbaum J., Rosenberg I.H., Wilson P.W., et al. Prevalence of cobalamin deficiency in the Framingham elderly population. Am J Clin Nutr 60 1 (1994) 2-11
86. Andres E., Loukili N.H., Noel E., et al. Vitamin B12 (cobalamin) deficiency in elderly patients. Can Med Assoc J 171 3 (2004) 251-259
87. Abyad A. Prevalence of vitamin B12 deficiency among demented patients and cognitive recovery with cobalamin replacement. J Nutr Health Aging 6 4 (2002) 254-260
88. Homocysteine Studies Collaboration. Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. JAMA 288 16 (2002) 2015-2022
89. Wald D.S., Law M., and Morris J.K. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 325 7374 (2002) 1202
90. Toole J.F., Malinow M.R., Chambless L.E., et al. Lowering homocysteine in patients with ischemic stroke to prevent recurrent stroke, myocardial infarction, and death: the Vitamin Intervention for Stroke Prevention (VISP) randomized controlled trial. JAMA 291 5 (2004) 565-575
91. Carmel R. Current concepts in cobalamin deficiency. Annu Rev Med 51 (2000) 357-375
92. McLean R.R., Jacques P.F., Selhub J., et al. Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med 350 5 (2004) 2042-2049
93. Wolters M., Strohle A., and Hahn A. Cobalamin: a critical vitamin in the elderly. Prev Med 39 6 (2004) 1256-1266
94. Rampersaud G.C., Kauwell G.P., and Bailey L.B. Folate: a key to optimizing health and reducing disease risk in the elderly. J Am Coll Nutr 22 1 (2003) 1-8
95. Arinzon Z., Fidelman Z., Peisakh A., et al. Folate status and folate related anemia: a comparative cross-sectional study of long-term care and post-acute care psychogeriatric patients. Arch Gerontol Geriatr 39 2 (2004) 133-142
96. Salles-Montaudon N., Parrot F., Balas D., et al. Prevalence and mechanisms of hyperhomocysteinemia in elderly hospitalized patients. J Nutr Health Aging 7 2 (2003) 111-116
97. Choumenkovitch S.F., Jacques P.F., Nadeau M.R., et al. Folic acid fortification increases red blood cell folate concentrations in the Framingham study. J Nutr 131 12 (2001) 3277-3280
98. Chapman I.M. Endocrinology of anorexia of ageing. Best Pract Res Clin Endocrinol Metab 18 3 (2004) 437-452