A new understanding of pancreatitis-associated pulmonary injury

Journal of Organ Dysfunction

Volumn 2, Issue 3, 2006, Pages 156-165

  Zhao, Xia ^a   Shi, Changbin ^a   Wang, Xiangdong ^a   Andersson, Roland ^a,b  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Acute pancreatitis; Acute respiratory distress syndrome; Adhesion molecules; Lung injury; Mast cells; Protein kinase C

Indexed keywords

CELL ADHESION MOLECULE; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN KINASE C; PROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE PANCREATITIS; DISEASE ASSOCIATION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; LEUKOCYTE; LUNG INJURY; LUNG LAVAGE; LUNG PARENCHYMA; MACROPHAGE; MAST CELL; MONOCYTE; MULTIPLE ORGAN FAILURE; NEUTROPHIL; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SEPSIS; SIGNAL TRANSDUCTION;

EID: 33748455055     PISSN: 17471060     EISSN: 17471079     Source Type: Journal    
DOI: 10.1080/17471060600799520     Document Type: Review

References (82)

1. Andersson R, Andersson B, Haraldsen P, Drewsen G, Eckerwall G. Incidence, management and recurrence rate of acute pancreatitis. Scand J Gastroenterol 2004;39:891-4.
2. Robertson CS, Basran GS, Hardy JG. Lung vascular permeability in patients with acute pancreatitis. Pancreas 1988;3:162-5.
3. Milani R, Pereira PM, Dolhnikoff M, Saldiva PHN, Martins NA. Respiratory mechanics and lung morphometry in severe pancreatitis-associated acute lung injury in rats. Crit Care Med 1995;23:1882-9.
4. Murakami H, Nakao A, Kishimoto W, Nakano M, Takagi H. Detection of O2-generation and neutrophil accumulation in rat lungs after acute necrotizing pancreatitis. Surgery 1995;118:547-54.
5. Wang XD, Börjesson A, Sun ZW, Wallen R, Deng XM, Zhang HY, et al. The association of type II pneumocytes and endothelial permeability with the pulmonary custocyte system in experimental acute pancreatitis. Eur J Clin Invest 1998;28:778-85.
6. Wang XD, Deng XM, Haraldsen P, Andersson R, Ihse I. Antioxidant and calcium channel blockers counteract endothelial barrier injury induced by acute pancreatitis in rats. Scand J Gastroenterol 1995;30:1129-36.
7. Denham W, Yang J, Norman J. Evidence for an unknown component of pancreatic ascites that induces adult respiratory distress syndrome through an interleukin-1 and tumor necrosis factor-dependent mechanism. Surgery 1997;122:295-301; discussion 301-2.
8. Wang X, Andersson R. The role of endothelial cells in the systemic inflammatory response syndrome and multiple system organ failure. Eur J Surg 1995;161:703-13.
9. Norman J. The role of cytokines in the pathogenesis of acute pancreatitis. Am J Surg 1998;175:76-83.
10. Bhatia M, Brady M, Shokuhi S, Christmas S, Neoptolemos JP, Slavin J. Inflammatory mediators in acute pancreatitis. J Pathol 2000;192:117-25.
11. Zhao X, Andersson R, Wang X, Dib M, Wang X. Acute pancreatitis-associated lung injury: pathophysiological mechanisms and potential future therapies. Scand J Gastroenterol 2002;37:1351-8.
12. Siflinger-Birnboim A, Johnson A. Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury. Am J Physiol Lung Cell Mol Physiol 2003;284: L435-51.
13. Zhao X, Dib M, Andersson E, Shi C, Widegren B, Wang X, et al. Alterations of adhesion molecule expression and inflammatory mediators in acute lung injury induced by septic and non-septic challenges. Lung 2005;183:87-100.
14. Parker JC, Falgout HJ, Grimbert FA, Taylor AE. The effect of increased vascular pressure on albumin-excluded volume and lung lymph flow in the dog lung. Circ Res 1980;47:866-75.
15. Closa D, Sabater L, Fernandez-Cruz L, Prats N, Gelpi E, Rosello-Catafau J. Activation of alveolar macrophages in lung injury associated with experimental acute pancreatitis is mediated by the liver. Ann Surg 1999;229:230-6.
16. Frossard JL, Saluja A, Bhagat L, Lee HS, Bhatia M, Hofbauer B, et al. The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology 1999;116:694-701.
17. Wang XD, Andersson R, Soltesz V, Ihse I. Gut origin sepsis, macrophage function, and oxygen extraction in acute pancreatitis in the rats. World J Surg 1996;20:299-308.
18. Sandoval D, Gukovskaya A, Reavey P, Gukovsky S, Sisk A, Braquet P, et al. The role of neutrophils and platelet-activating factor in mediating experimental pancreatitis. Gastroenterology 1996;111:1081-91.
19. Lundberg AH, Granger DN, Russell J, Sabek O, Henry J, Gaber L, et al. Quantitative measurement of P- and E-selectin adhesion molecules in acute pancreatitis: correlation with distant organ injury. Ann Surg 2000;231:213-22.
20. Zhao X, Dib M, Wang X, Widegren B, Andersson R. Influence of mast cells on the expression of adhesion molecules on circulating and migrating leukocytes in acute pancreatitis-associated lung injury. Lung 2005;183:253-64.
21. Mann DV, Kalu P, Foulds S, Edwards R, Glazer G. Neutrophil activation and hyperamylasemia after endoscopic retrograde cholangiopancreatography: potential role for the leukocyte in the pathogenesis of acute pancreatitis. Endoscopy 2001;33:453-88.
22. Brivet FG, Emilie D, Galanaud P. Pro- and anti-inflammatory cytokines during acute severe pancreatitis: an early and sustained response, although unpredictable of death. Parisian Study Group on Acute Pancreatitis. Crit Care Med 1999;27:749-55.
23. Frossard JL, Saluja AL, Bhagat L, Lee HS, Bhatia M, Hofbauer B, et al. The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology 1999;116:694-701.
24. Folch E, Salas A, Panes J, Gelpi E, Rosello-Catafau J, Anderson DC, et al. Role of P-selectin and ICAM-1 in pancreatitis-induced lung inflammation in rats: significance of oxidative stress. Ann Surg 1999;230:792-8.
25. Lundberg AH, Fukatsu K, Gaber L, Callicutt S, Kotb M, Wilcox H, et al. Blocking pulmonary ICAM-1 expression ameliorates lung injury in established diet-induced pancreatitis. Ann Surg 2001;233:213-20.
26. Paajanen H, Laato M, Jaakkola M, Pulkki K, Niinikoski J, Nordback I. Serum tumor necrosis factor compared with C reactive protein in the early assessment of severity of acute pancreatitis. Br J Surg 1995;82:271-3.
27. De Dios I, Perez M, de La Mano A, Sevillano S, Orfao A, Ramudo L, et al. Contribution of circulating leukocytes to cytokine production in pancreatic duct obstruction-induced acute pancreatitis in rats. Cytokine 2002;/20:/295-303.
28. Rau B, Baumgart K, Kruger CM, Schilling M, Beger HG. CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications. Intensive Care Med 2003;29:622-9.
29. Dib M, Zhao X, Wang XD, Andersson R. Role of mast cells in the development of pancreatitis-induced multiple organ dysfunction. Br J Surg 2002;89:172-8.
30. Tharp MD. The interaction between mast cells and endothelial cells. J Invest Dermatol 1989;93(2Suppl):107S-12S.
31. Dowdall JF, Winter DC, Baird AW, Bouchier-Hayes D. Biological role and clinical implications of mast cells in surgery. Surgery 2002;132:1-4.
32. Kubes P, Kanwar S. Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event. J Immunol 1994;152:3570-7.
33. Gaboury JP, Johnston B, Niu XF, Kubes P. Mechanisms underlying acute mast cell-induced leukocyte rolling and adhesion in vivo. J Immunol 1995;154:804-13.
34. Raud J, Dahlen SE, Smedegard G, Hedqvist P. An intravital microscopic model for mast cell-dependent inflammation in the hamster cheek pouch. Acta Physiol Scand 1989;135:95-105.
35. Wershil BK, Wang ZS, Gordon JR, Galli SJ. Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha. J Clin Invest 1991;87:446-53.
36. Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard NP, Lu B, et al. Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. J Clin Invest 1997;100:2022-7.
37. Delneste Y, Lassalle P, Jeannin P, Joseph M, Tonnel AB, Gosset P. Histamine induces IL-6 production by human endothelial cells. Clin Exp Immunol 1994;98:344-9.
38. Jeannin P, Delneste Y, Gosset P, Molet S, Lassalle P, Hamid Q, et al. Histamine induces interleukin-8 secretion by endothelial cells. Blood 1994;84:2229-33.
39. Miki I, Kusano A, Ohta S, Hanai N, Otoshi M, Masaki S, et al. Histamine enhanced the TNF-alpha-induced expression of E-selectin and ICAM-1 on vascular endothelial cells. Cell Immunol 1996;171:285-8.
40. Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 1989;264:7768-71.
41. Jones DA, Abbassi O, McIntire LV, McEver RP, Smith CW. P-selectin mediates neutrophil rolling on histamine-stimulated endothelial cells. Biophys J 1993;65:1560-9.
42. Dib M, Zhao X, Wang X, Andersson R. Mast cells contribute to early pancreatitis-induced systemic endothelial barrier dysfunction. Pancreatology 2002;2:396-401.
43. Tromp SC, Tangelder GJ, Slaaf DW, Reneman RS, van-Velzen S, Engels W. The role of mast cells and histamine in leukocyte-endothelium interactions in four rat strains. Pflugers Arch 1998;436:255-61.
44. Walsh LJ, Trinchieri G, Waldorf HA, Whitaker D, Murphy GF. Human dermal mast cells contain and release tumor necrosis factor alpha, which induced endothelial leukocyte adhesion molecule 1. Proc Natl Acad Sci USA 1991;88:4220-4.
45. Metcalfe DD, Baram D, Mekori YA. Mast cells. Physiol Rev 1997;77:1033-79.
46. O'Neill S, O'Neill AJ, Conroy E, Brady HR, Fitzpatrick JM, Watson RW. Altered caspase expression results in delayed neutrophil apoptosis in acute pancreatitis. J Leukoc Biol 2000;68:15-20.
47. Norman JG, Fink GW, Denham W, Yang J, Carter G, Sexton C, et al. Tissue-specific cytokine production during experimental acute pancreatitis. Dig Dis Sci 1997;42:1783-8.
48. Park WY, Goodman RB, Steinberg KP, Ruzinski JT, Radella 2nd F, Park DR, et al. Cytokine balance in the lungs of patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2001;164:1896-903.
49. Granell S, Serrano-Mollar A, Folch-Puy E, Navajas D, Farre R, Bulbena O, et al. Oxygen in the alveolar air space mediates lung inflammation in acute pancreatitis. Free Radic Biol Med 2004;37:1640-7.
50. Mikami Y, Takeda K, Shibuya K, Qiu-Feng H, Egawa S, Sunamura M, et al. Peritoneal inflammatory cells in acute pancreatitis: relationship of infiltration dynamics and cytokine production with severity of illness. Surgery 2002;132:86-92.
51. Bhatia M, Ramnath RD, Chevali L, Guglielmotti A. Treatment with bindarit, a blocker of MCP-1 synthesis, protects mice against acute pancreatitis. Am J Physiol Gastrointest Liver Physiol 2005;288:G1259-65.
52. Zhao X, Shi C, Wang X, Andersson R. Protein kinase C modulates the pulmonary inflammatory response in acute pancreatitis. Respir Physiol Neurobiol 2006;152:16-26.
53. Norman JG, Franz MG, Fink GS, Messina J, Fabri PJ, Gower WR, et al. Decreased mortality of severe acute pancreatitis after proximal cytokine blockade. Ann Surg 1995;221:625-31.
54. Kusske AM, Rongione AJ, Ashley SW, McFadden DW, Reber HA. Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice. Surgery 1996;120:284-8; discussion 289.
55. Norman JG, Fink GW, Sexton C, Carter G. Transgenic animals demonstrate a role for the IL-1 receptor in regulating IL-1beta gene expression at steady-state and during the systemic stress induced by acute pancreatitis. J Surg Res 1996;63:231-6.
56. Rongione AJ, Kusske AM, Kwan K, Ashley SW, Reber HA, McFadden DW. Interleukin 10 reduces the severity of acute pancreatitis in rats. Gastroenterology 1997;112:960-7.
57. Mayer J, Rau B, Gansauge F, Beger HG. Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications. Gut 2000;47:546-52.
58. Shi C, Zhao X, Lagergren A, Sigvardsson M, Wang X, Andersson R. Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis. Scand J Gastroenterol 2006;41:472-80.
59. Kusske AM, Rongione AJ, Reber HA. Cytokines and acute pancreatitis. Gastroenterology 1996;110:639-42.
60. Rongione AJ, Kusske AM, Reber HA, Ashley SW, McFadden DW. Interleukin-10 reduces circulating levels of serum cytokines in experimental pancreatitis. J Gastrointest Surg 1997;1:159-66.
61. Osman MO, Jacobsen NO, Kristensen JU, Deleuran B, Gesser B, Larsen CG, et al. IT 9302, a synthetic interleukin-10 agonist, diminishes acute lung injury in rabbits with acute necrotizing pancreatitis. Surgery 1998;124:584-92.
62. Thomassen MJ, Divis LT, Fisher CJ. Regulation of human alveolar macrophage inflammatory cytokine production by interleukin-10. Clin Immunol Immunopathol 1996;80:321-4.
63. Zou WG, Wang DS, Lang MF, Jin DY, Xu DH, Zheng ZC, et al. Human interleukin 10 gene therapy decreases the severity and mortality of lethal pancreatitis in rats. J Surg Res 2002;103:121-6.
64. Van Laethem JL, Eskinazi R, Louis H, Rickaert F, Robberecht P, Deviere J. Multisystemic production of interleukin 10 limits the severity of acute pancreatitis in mice. Gut 1998;43:408-13.
65. Makhija R, Kingsnorth AM. Cytokine storm in acute pancreatitis. J Hepatobiliary Pancreat Surg 2002;9:401-10.
66. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
67. Chung KF. Cytokines in chronic obstructive pulmonary disease. Eur Respir J 2001;34:50s-9s.
68. Shen GX. Selective protein kinase C inhibitors and their applications. Curr Drug Targets Cardiovasc Haematol Disord 2003;3:301-7.
69. Isakov N, Altman A. Protein kinase C (theta) in T cell activation. Annu Rev Immunol 2002;20:761-94.
70. Hu HL, Forsey RJ, Blades TJ, Barratt ME, Parmar P, Powell JR. Antioxidants may contribute in the fight against ageing: an in vitro model. Mech Ageing Dev 2000;121:217-30.
71. Zhao H, Zhao X, Bai CX, Wang X. Potential factors of interorgan signals in the development of pancreatitis-associated acute lung injury and acute respiratory distress syndrome. J Organ Dysfunct 2005;1:32-44.
72. Muhs BE, Patel S, Yee H, Marcus S, Shamamian P. Increased matrix metalloproteinase expression and activation following experimental acute pancreatitis. J Surg Res 2001;101:21-8.
73. Alexander JP, Acott TS. Involvement of protein kinase C in TNFalpha regulation of trabecular matrix metalloproteinases and TIMPs. Invest Ophthalmol Vis Sci 2001;42:2831-8.
74. Gao HK, Zhou ZG, Chen YQ, Han FH, Wang C. Expression of platelet endothelial cell adhesion molecule-1 between pancreatic microcirculation and peripheral circulation in rats with acute edematous pancreatitis. Hepatobiliary Pancreat Dis Int 2003;2:463-6.
75. Gong N, Wei H, Chowdhury SH, Chatterjee S. Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells. Proc Natl Acad Sci USA 2004;101:6490-5.
76. Albelda SM, Lau KC, Chien P, Huang ZY, Arguiris E, Bohen A, et al. Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcgamma receptor function. Am J Respir Cell Mol Biol 2004;31:246-55.
77. Lynch JJ, Ferro TJ, Blumenstock FA, Brockenauer AM, Malik AB. Increased endothelial albumin permeability mediated by protein kinase C activation. J Clin Invest 1990;85:1991-8.
78. Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol 1994;267:L223-41.
79. Lopez-Ongil S, Torrecillas G, Perez-Sala D, Gonzalez-Santiago L, Rodriguez-Puyol M, Rodriguez-Puyol D. Mechanisms involved in the contraction of endothelial cells by hydrogen peroxide. Free Radic Biol Med 1999;26:501-10.
80. Dempsey EC, Newton AC, Mochly-Rosen D, Fields AP, Reyland ME, Insel PA, et al. Protein kinase C isozymes and the regulation of diverse cell responses. Am J Physiol Lung Cell Mol Physiol 2000;279:L429-38.
81. Lee WL, Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care 2001;7:1-7.
82. Toullec D, Pianetti P, Coste H, Bellevergue P, Grand-Perret T, Ajakane M, et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C. J Biol Chem 1991;266:15771-81.