Stereochemically pure α-trifluoromethyl-malic hydroxamates: synthesis and evaluation as inhibitors of matrix metalloproteinases

Tetrahedron

Volumn 62, Issue 43, 2006, Pages 10171-10181

  Moreno, Margherita ^a   Sani, Monica ^b   Raos, Guido ^a   Meille, Stefano V ^a   Belotti, Dorina ^c   Giavazzi, Raffaella ^c   Bellosta, Stefano ^d   Volonterio, Alessandro ^a   Zanda, Matteo ^b  

^a POLITECNICO DI MILANO   (Italy)

^b CNR   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TRIFLUOROMETHYL MALIC HYDROXAMATE DERIVATIVE; FLUORINE DERIVATIVE; GELATINASE A; GELATINASE B; HYDROXAMIC ACID; MALIC ACID DERIVATIVE; MATRIX METALLOPROTEINASE INHIBITOR; N ACYL OXAZOLIDINE 2 THIONE; OXAZOLIDINE DERIVATIVE; PYRUVIC ACID DERIVATIVE; TRIFLUOROPYRUVATE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; DIASTEREOISOMER; ENZYME INHIBITION; MOLECULAR MODEL; PRIORITY JOURNAL; STEREOCHEMISTRY; SYNTHESIS; ZYMOGRAPHY;

EID: 33748437500     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.08.036     Document Type: Article

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