Modulation of murine experimental allergic conjunctivitis by treatment with α-galactosylceramide

Immunology Letters

Volumn 107, Issue 1, 2006, Pages 32-40

  Fukushima, Atsuki ^a   Sumi, Tamaki ^a   Fukuda, Ken ^b   Yamaguchi, Tomoko ^a   Kumagai, Naoki ^b   Nishida, Teruo ^b   Ueno, Hisayuki ^a  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b YAMAGUCHI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Galactosylceramide; Allergic conjunctivitis; Eosinophil; NKT cell

Indexed keywords

ALPHA GALACTOSYLCERAMIDE; EYE DROPS; GAMMA INTERFERON; IMMUNOGLOBULIN; RAGWEED ANTIGEN; TRANSCRIPTION FACTOR FOXP3;

ALLERGIC CONJUNCTIVITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL PROLIFERATION; CONJUNCTIVA; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; EOSINOPHIL; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SERUM; SPLEEN; TH2 CELL; UPREGULATION;

ALLERGENS; AMBROSIA; ANIMALS; CONJUNCTIVITIS, ALLERGIC; DOWN-REGULATION; EOSINOPHILS; GALACTOSYLCERAMIDES; INTERFERON TYPE II; KILLER CELLS, NATURAL; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; POLLEN;

EID: 33748288074     PISSN: 01652478     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imlet.2006.07.001     Document Type: Article

References (34)

1. Trocme S.D., and Sra K.K. Spectrum of ocular allergy. Curr Opin Allergy Clin Immunol 2 (2002) 423-427
2. Fukagawa K., Nakajima T., Tsubota K., Shimmura S., Saito H., and Hirai K. Presence of eotaxin in tears of patients with atopic keratoconjunctivitis with severe corneal damage. J Allergy Clin Immunol 103 (1999) 1220-1221
3. Messmer E.M., May C.A., Stefani F.H., Welge-Luessen U., and Kampik A. Toxic eosinophil granule protein deposition in corneal ulcerations and scars associated with atopic keratoconjunctivitis. Am J Ophthalmol 134 (2002) 816-821
4. Halken S. Prevention of allergic disease in childhood: clinical and epidemiological aspects of primary and secondary allergy prevention. Pediatr Allergy Immunol 15 (2004) 9-32
5. Kumagai N., Fukuda K., Fujitsu Y., Yamamoto K., and Nishida T. Role of structural cells of the cornea and conjunctiva in the pathogenesis of vernal keratoconjunctivitis. Prog Retin Eye Res 25 (2006) 165-187
6. Fukushima A., Yoshida H., Iwamoto H., Yoshida O., and Ueno H. The role of cellular immunity both in the induction and effector phases of experimental allergic blepharoconjunctivitis (EAC) in rats. Exp Eye Res 65 (1997) 631-637
7. Yoshida O., Yoshida H., Iwamoto H., Nishino K., Fukushima A., and Ueno H. Genetic background determines the nature of immune responses and experimental immune-mediated blepharoconjunctivitis (EC). Curr Eye Res 18 (1999) 117-124
8. Iwamoto H., Nishino K., Magone T.M., Whitcup S.M., Yoshida O., Yoshida H., et al. Experimental immune-mediated blepharoconjunctivitis in rats induced by immunization with ragweed pollen. Graefes Arch Clin Exp Ophthalmol 238 (2000) 346-351
9. Fukushima A., Ozaki A., Jian Z., Ishida W., Fukata K., Ueno H., et al. Dissection of antigen-specific humoral and cellular immune responses for the development of experimental immune-mediated blepharoconjunctivitis in C57BL/6 mice. Curr Eye Res 30 (2005) 241-248
10. Fukushima A., Yamaguchi T., Ishida W., Fukata K., Mittler R.S., Yagita H., et al. Engagement of 4-1BB inhibits the development of experimental allergic conjunctivitis in mice. J Immunol 175 (2005) 4897-4903
11. Fukushima A., Yamaguchi T., Ishida W., Fukata K., Yagita H., and Ueno H. Roles of OX40 in the development of murine experimental allergic conjunctivitis: exacerbation and attenuation by stimulation and blocking of OX40. Invest Ophthalmol Vis Sci 47 (2006) 657-663
12. Fukushima A., Yamaguchi T., Ishida W., Fukata K., Yagita H., and Ueno H. The interaction between ICOS and B7RP-1 is not required for the development of experimental murine allergic conjunctivitis. Biochem Biophys Res Commun 338 (2005) 1726-1731
13. Ozaki A., Seki Y., Fukushima A., and Kubo M. The control of allergic conjunctivitis by suppressor of cytokine signaling (SOCS)3 and SOCS5 in a murine model. J Immunol 175 (2005) 5489-5497
14. Kelso A. Th1 and Th2 subsets: paradigms lost?. Immunol Today 16 (1995) 374-379
15. Fukushima A., Fukata K., Ozaki A., Takata M., Kuroda N., Enzan H., et al. Exertion of the suppressive effects of IFN-γ on experimental immune mediated blepharoconjunctivitis in Brown Norway rats during the induction phase but not the effector phase. Br J Ophthalmol 86 (2002) 1166-1171
16. Magone M.T., Whitcup S.M., Fukushima A., Chan C.C., Silver P.B., and Rizzo L.V. The role of IL-12 in the induction of late-phase cellular infiltration in a murine model of allergic conjunctivitis. J Allergy Clin Immunol 105 (2000) 299-308
17. Fukushima A., Yamaguchi T., Ishida W., Fukata K., Taniguchi T., Liu F.T., et al. Genetic background determines susceptibility to experimental immune-mediated blepharoconjunctivitis: comparison of Balb/c and C57BL/6 mice. Exp Eye Res 82 (2006) 210-218
18. Fukushima A., Yamaguchi T., Ishida W., Fukata K., Ozaki A., and Ueno H. The immunization protocol determines whether endogenous interferon-γ suppresses the infiltration of eosinophils into the conjunctiva. Immunol Lett 100 (2005) 189-194
19. Kronenberg M. Toward an understanding of NKT cell biology: progress and paradoxes. Annu Rev Immunol 23 (2005) 877-900
20. Korsgren M., Persson C.G., Sundler F., Bjerke T., Hansson T., Chambers B.J., et al. Natural killer cells determine development of allergen-induced eosinophilic airway inflammation in mice. J Exp Med 189 (1999) 553-562
21. Akbari O., Stock P., Meyer E., Kronenberg M., Sidobre S., Nakayama T., et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med 9 (2003) 582-588
22. Lisbonne M., Diem S., de Castro Keller A., Lefort J., Araujo L.M., Hachem P., et al. Invariant Vα 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model. J Immunol 171 (2003) 1637-1641
23. Hachem P., Lisbonne M., Michel M.L., Diem S., Roongapinun S., Lefort J., et al. α-galactosylceramide-induced iNKT cells suppress experimental allergic asthma in sensitized mice: role of IFN-γ. Eur J Immunol 35 (2005) 2793-2802
24. Morishima Y., Ishii Y., Kimura T., Shibuya A., Shibuya K., Hegab A.E., et al. Suppression of eosinophilic airway inflammation by treatment with α-galactosylceramide. Eur J Immunol 35 (2005) 2803-2814
25. Matsuda H., Suda T., Sato J., Nagata T., Koide Y., Chida K., et al. α-Galactosylceramide, a ligand of natural killer T cells, inhibits allergic airway inflammation. Am J Respir Cell Mol Biol 33 (2005) 22-31
26. Fukushima A., Yamaguchi T., Azuma M., Yagita H., and Ueno H. Involvement of programmed death-ligand 2 (PD-L2) in the development of experimental allergic conjunctivitis in mice. Br J Ophthalmol 90 (2006) 1040-1045
27. Fasler S., Aversa G., Terr A., Thestrup-Pedersen K., de Vries J.E., and Yssel H. Peptide-induced anergy in allergen-specific human Th2 cells results in lack of cytokine production and B cell help for IgE synthesis. Reversal by IL-2, not by IL-4 or IL-13. J Immunol 155 (1995) 4199-4206
28. Yoshida H., Yoshida O., Iwamoto H., Nishino K., Hashida M., Fukushima A., et al. Analysis of effects of stimulation in vitro of ovalbumin primed lymph node cells on adoptive transfer of experimental immune mediated blepharoconjunctivitis in Lewis rats. Br J Ophthalmol 82 (1998) 1189-1194
29. Ozaki A., Fukushima A., Fukata K., and Ueno H. Effects of IL-4 and IL-12 on experimental immune-mediated blepharoconjunctivitis in Brown Norway rats. Clin Exp Immunol 122 (2000) 28-34
30. + regulatory T cells for immunologic self-tolerance and negative control of immune responses. Annu Rev Immunol 22 (2004) 531-562
31. + T regulatory cells in the prevention of autoimmune myasthenia. J Immunol 175 (2005) 7898-7904
32. + T cells protect against experimentally induced asthma and alter pulmonary dendritic cell phenotype and function. J Exp Med 202 (2005) 1549-1561
33. + regulatory T cells is interleukin 10 dependent. J Exp Med 202 (2005) 1539-1547
34. Rothenberg M.E., and Hogan S.P. The eosinophil. Annu Rev Immunol 24 (2006) 147-174