Toxic eosinophil granule protein deposition in corneal ulcerations and scars associated with atopic keratoconjunctivitis

American Journal of Ophthalmology

Volumn 134, Issue 6, 2002, Pages 816-821

  Messmer, Elisabeth M ^a   May, C Albrecht ^b   Stefani, Fritz H ^a   Welge Luessen, Ulrich ^a   Kampik, Anselm ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EOSINOPHIL CATIONIC PROTEIN; MAJOR BASIC PROTEIN;

AGED; ARTICLE; CASE REPORT; CELL MIGRATION; CELL VIABILITY; CORNEA EPITHELIUM; CORNEA EROSION; CORNEA STROMA; CORNEA ULCER; DISEASE ASSOCIATION; EOSINOPHIL; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IN VITRO STUDY; KERATOCONJUNCTIVITIS; MALE; MICROSCOPY; MORPHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECURRENT DISEASE;

AGED; BLOOD PROTEINS; CICATRIX; CONJUNCTIVITIS, ALLERGIC; CORNEA; CORNEAL ULCER; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; INFLAMMATION MEDIATORS; MALE; MICROSCOPY, FLUORESCENCE; RIBONUCLEASES;

EID: 18744399814     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9394(02)01726-9     Document Type: Article

References (30)

1. Hogan M.J. Atopic keratoconjunctivitis. Trans Am Ophthalmol Soc. 50:1952;265-281.
2. Hogan M.J. Atopic keratoconjunctivitis. Am J Ophthalmol. 36:1953;937-947.
3. Foster C.S., Rice B.A., Dutt J.E. Immunopathology of atopic keratoconjunctivitis. Ophthalmology. 98:1991;1190-1196.
4. Avunduk A.M., Avunduk M.C., Dayanir V., Tekelioglu Y. Further studies on the immunopathology of atopic keratoconjunctivitis using flow cytometry. Exp Eye Res. 65:1997;803-808.
5. Avunduk A.M., Avunduk M.C., Tekelioglu Y. Analysis of tears in patients with atopic keratoconjunctivitis using flow cytometry. Ophthalmic Res. 30:1998;44-48.
6. Yoshida A., Imayama S., Sugai S., Kawano Y., Ishibashi T. Increased number of IgE positive Langerhans cells in the conjunctiva of patients with atopic dermatitis. Br J Ophthalmol. 81:1997;402-406.
7. Trocme S.D., Kephart G.M., Bourne W.M., Buckley R.J., Gleich G.J. Eosinophil granule major basic protein deposition in corneal ulcers associated with vernal keratoconjunctivitis. Am J Ophthalmol. 115:1993;640-643.
8. Metz D.P., Bacon A.S., Holgate S., Lightman S.L. Phenotypic characterization of T cells infiltrating the conjunctiva in chronic allergic eye disease. J Allergy Clin Immunol. 98:1996;686-696.
9. Dvorak A.M., Ackerman S.J., Weller P.F. Subcellular morphology and biochemistry of eosinophils. Smolin G.S., O'Connor G.R. Ocular immunology. 1986;237 Little Brown, Boston.
10. Thomas L.L., Zheutlin L.M., Gleich G.J. Pharmacological control of human basophil histamine release stimulated by eosinophil granule major basic protein. Immunology. 66:1989;611-615.
11. Moy J.N., Gleich G.J., Thomas L.L. Noncytotoxic activation of neutrophils by eosinophil granule major basic protein. Effect on superoxide anion generation and lysosomal enzyme release. J Immunol. 145:1990;2626-2632.
12. Frigas E., Loegering D.A., Gleich G.J. Cytotoxic effects of the guinea pig eosinophil major protein on tracheal epithelium. Lab Invest. 42:1980;35-43.
13. Filley W.V., Holley K.E., Kephart G.M., Gleich G.J. Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet. 2:1982;11-16.
14. Leiferman K.M., Ackerman S.J., Sampson H.A., Haugen H.S., Venencie P.Y., Gleich G.J. Dermal deposition of eosinophil granule major basic protein in atopic dermatitis. Comparison with onchocerciasis. N Engl J Med. 313:1985;282-285.
15. Trocme S.D., Gleich G.J., Kephart G.M., Zieske J.D. Eosinophil granule major basic protein inhibition of corneal epithelial wound healing. Invest Ophthalmol Vis Sci. 35:1994;3051-3056.
16. Zheutlin L.M., Ackerman S.J., Gleich G.J., Thomas L.L. Stimulation of basophil and rat mast cell histamine release by eosinophil granule-derived cationic proteins. J Immunol. 133:1984;. 2180-1285.
17. Hernnas J., Sarnstrand B., Lindroth P., Peterson C.G., Venge P., Malmstrom A. Eosinophil cationc protein alters proteoglycan metabolism in human lung fibroblast cultures. Eur J Cell Biol. 59:1992;352-363.
18. Motojima S., Frigas E., Loegering D.A., Gleich G.J. Toxicity of eosinophil cationic proteins for guinea pig tracheal epithelium in vitro. Am Rev Respir Dis. 139:1989;801-805.
19. Tai P.C., Ackerman S.J., Spry C.J., Dunnette S., Olsen E.G., Gleich G.J. Deposits of eosinophil granule proteins in cardiac tissues of patients with eosinophilic endomyocardial disease. Lancet. 1:1987;643-647.
20. Trocme S.D., Hallberg C.K., Gill K.S., Gleich G.J., Tyring S.K., Brysk M.M. Effects of eosinophil granule proteins on human corneal epithelial cell viability and morphology. Invest Ophthal Vis Sci. 38:1997;593-599.
21. Kapp A., Czech W., Krutmann J., Schöpf E. Eosinophil cationic protein in sera of patients with atopic dermatitis. J Am Acad Dermatol. 24:1991;555-558.
22. Porter D.P., Trocme S.D., Foster C.S., Dohlman C.H. Conjunctival deposition of eosinophil major basic protein, neutrophil elastase, and mast cell tryptase in atopic keratoconjunctivitis. Invest Ophthalmol Vis Sci. 34:(Suppl):1993;855.
23. Udell I.J., Gleich G.J., Allansmith M.R., Ackerman S.J., Abelson M.B. Eosinophil granule major basic protein and Charcot-Leyden crystal protein in human tears. Am J Ophthalmol. 92:1981;824-828.
24. Bonini S., Magrini L., Rotiroti G., et al. The eosinophil and the eye. Allergy. 52:(Suppl):1997;44-47.
25. Trocme S.D., Kephart G.M., Allansmith M.R., Bourne W.M., Gleich G.J. Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-associated giant papillary conjunctivitis. Am J Ophthalmol. 108:1989;57-63.
26. Trocme S.D., Kephart G.M., Bourne W.M., Maguire L.J., Gleich G.J. Eosinophil granule major basic protein in contact lenses of patients with giant papillary conjunctivitis. CLAO J. 16:1990;219-222.
27. Fukagawa K., Nakajima T., Tsubota K., Shimmura S., Saito H., Hirai K. Presence of eotaxin in tears of patients with atopic keratoconjunctivitis with severe corneal damage. J Allergy Clin Immunol. 103:1999;1220-1221.
28. Young J.D., Peterson C.G., Venge P., Cohn Z.A. Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature. 321:1986;613-616.
29. Abu-Ghazaleh R.I., Gleich G.J., Prendergast F.G. Interaction of eosinophil granule major basic protein with synthetic lipid bilayers a mechanism for toxicity. J Membr Biol. 128:1992;153-164.
30. Buckley R.J. Vernal keratopathy and its management. Trans Ophthalmol Soc UK. 101:1981;234-238.