A potential novel mechanism involving connexin 43 gap junction for control of Sertoli cell proliferation by thyroid hormones

Journal of Cellular Physiology

Volumn 209, Issue 1, 2006, Pages 153-161

  Gilleron, Jerome ^a   Nebout, Marielle ^a   Scarabelli, Linda ^b   Senegas Balas, Francoise ^a   Palmero, Silvio ^b   Segretain, Dominique ^a   Pointis, Georges ^a  

^a INSERM   (France)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CONNEXIN 43; CYTOCHALASIN D; DNA; GLYCYRRHETINIC ACID; GREEN FLUORESCENT PROTEIN; LIOTHYRONINE; OLEAMIDE; PROPYLTHIOURACIL; THYMIDINE; THYROID HORMONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSKELETON; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GAP JUNCTION; GENETIC TRANSFECTION; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; SERTOLI CELL;

ANIMALS; ANIMALS, NEWBORN; CELL LINE; CELL PROLIFERATION; CONNEXIN 43; GAP JUNCTIONS; MALE; MICE; MICE, TRANSGENIC; PHENYLTHIOUREA; RATS; RATS, WISTAR; SEMINIFEROUS TUBULES; SERTOLI CELLS; THYROID HORMONES; TRANSFECTION; TRIIODOTHYRONINE;

EID: 33748282756     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20716     Document Type: Article

References (65)

1. Anasti JN, Flack MR, Froehlich J, Nelson LM, Nisula BC. 1995. A potential novel mechanism for precocious puberty in juvenile hypothyroidism. J Clin Endocrinol Metab 80:276-279.
2. Ando S, Sirianni R, Forastieri P, Casaburi I, Lanzino M, Rago V, Giordano F, Giordano C, Carpino A, Pezzi V. 2001. Aromatase expression in prepuberal Sertoli cells: Effect of thyroid hormone. Mol Cell Endocrinol 178:11-21.
3. Batias C, Siffroi JP, Fenichel P, Pointis G, Segretain D. 2000. Connexin43 gene expression and regulation in the rodent seminiferous epithelium. J Histochem Cytochem 48:793-805.
4. Bourdon V, Lablack A, Abbe P, Segretain D, Pointis G. 1998. Characterization of a clonal Sertoli cell line using adult PyLT transgenic mice. Biol Reprod 58:591-599.
5. Bravo-Moreno JF, Diaz-Sanchez V, Montoya-Flores JG, Lamoyi E, Saez JC, Perez-Armendariz EM. 2001. Expression of connexin43 in mouse Leydig, Sertoli, and germinal cells at different stages of postnatal development. Anat Rec 264:13-24.
6. Bruder JM, Samuels MH, Bremner WJ, Ridgway EC, Wierman ME. 1995. Hypothyroidism-induced macroorchidism: Use of a gonadotropin-releasing hormone agonist to understand its mechanism and augment adult stature. J Clin Endocrinol Metab 80:11-16.
7. Bruzzone R, White TW, Goodenough DA. 1996. The cellular Internet: On-line with connexins. Bioessays 18:709-718.
8. Buzzard JJ, Morrison JR, O'Bryan MK, Song Q, Wreford NG. 2000. Developmental expression of thyroid hormone receptors in the rat testis. Biol Reprod 62:664-669.
9. Buzzard JJ, Wreford NG, Morrison JR. 2003. Thyroid hormone, retinoic acid, and testosterone suppress proliferation and induce markers of differentiation in cultured rat sertoli cells. Endocrinology 144:3722-3731.
10. Canale D, Agostini M, Giorgilli G, Caglieresi C, Scartabelli G, Nardini V, Jannini EA, Martino E, Pinchera A, Macchia E. 2001. Thyroid hormone receptors in neonatal, prepubertal, and adult rat testis. J Androl 22:284-288.
11. Cheng CY, Mruk DD. 2002. Cell junction dynamics in the testis: Sertoli-germ cell interactions and male contraceptive development. Physiol Rev 82:825-874.
12. Clairmont A, Tessman D, Stock A, Nicolai S, Stahl W, Sies H. 1996. Induction of gap junctional intercellular communication by vitamin D in human skin fibroblasts is dependent on the nuclear vitamin D receptor. Carcinogenesis 17:1389-1391.
13. Cooke PS, Hess EA, Porcelli J, Meisami E. 1991. Increased sperm production in adult rats after transient neonatal hypothyroidism. Endocrinology 129:244-248.
14. Cooke PS, Hess RA, Kirby JD, Bunick D, Hardy MP. 1994. Neonatal propylthiouracil treatment as a model system for studying factors controlling testis growth and sperm production. In: Bartke A, editor. Function of somatic cells in the testis. New York: Springer-Verlag, pp 400-407.
15. Davies PJ, Davis MB. 1996. Nongenomic actions of thyroid hormone. Thyroid 6:497-504.
16. Decker RS. 1976. Hormonal regulation of gap junction differentiation. J Cell Biol 69:669-685.
17. Decrouy X, Gasc JM, Pointis G, Segretain D. 2004. Functional characterization of Cx43 based gap junctions during spermatogenesis. J Cell Physiol 200:146-154.
18. Fiorini C, Mograbi B, Cronier L, Bourget I, Decrouy X, Ferrua B, Malassine A, Samson M, Fenichel P, Segretain D, Pointis G. 2004. The dominant negative effect of connexin 33 on gap junctional intercellular communication is mediated through a selective sequestration of connexin 43. J Cell Sc 117:4665-4672.
19. Fischer R, Reinehr R, Lu TP, Schonicke A, Warskulat U, Dienes HP, Haussinger D. 2005. Intercellular communication via gap junctions in activated rat hepatic stellate cells. Gastroenterology 128:433-448.
20. Francavilla S, Cordeschi G, Properzi G, Jiannini EA, Palmero S, Fugassa E, Loras B, D'Armiento M. 1991. The effect of thyroid hormone on prenatal and postnatal development of the rat testis. J Endocrinol 129:35-42.
21. Fugassa E, Palmero S, Gallo G. 1987. Triiodothyronine decreases the production of androgen binding protein by rat Sertoli cells. Biochem Biophys Res Commun 143:241-247.
22. Giesmann D, Theiss C, Breipohl W, Meller K. 2003. Microinjection of actin antibodies impaired gap junctional intercellular communication in lens epithelial cells in vitro. Curr Eye Res 27:157-164.
23. Hernandez-Blazquez FJ, Joazeiro PP, Omori Y, Yamasaki H. 2001. Control of intracellular movement of connexins by E-cadherin in murine skin papilloma cells. Exp Cell Res 270:235-247.
24. Hess RA, Cooke PS, Bunick D, Kirby JD. 1993. Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell number. Endocrinology 132:2607-2613.
25. Holsberger DR, Cooke PS. 2005. Understanding the role of thyroid hormone in Sertoli cell development: A mechanistic hypothesis. Cell Tissue Res 322:133-140.
26. Holsberger DR, Kiesewetter SE, Cooke PS. 2005. Regulation of neonatal Sertoli cell development by thyroid hormone receptor alpha1. Biol Reprod 73:396-403.
27. Huynh HT, Alpert L, Laird DW, Batist G, Chalifour L, Alaoui-Jamali MA. 2001. Regulation of the gap junction connexin 43 gene by androgens in the prostate. J Mol Endocrinol 26:1-10.
28. Incerpi S, De Vito P, Luly P, Spagnuolo S, Leoni S. 2002. Short-term effects of thyroid hormones and 3,5-diiodothyronme on membrane transport systems in chick embryo hepatocytes. Endocrinology 143:1660-1668.
29. Jannini EA, Olivieri M, Francavilla S, Gulino A, Ziparo E, D'Armiento M. 1990. Ontogenesis of the nuclear 3,5,3′-triiodothyronine receptor in the rat testis. Endocrinology 126:2521-2526.
30. Jannini EA, Ulisse S, D'Armiento M. 1995. Thyroid hormone and male gonadal function. Endocr Rev 16:443-449.
31. Juneja SC, Barr KJ, Enders GC, Kidder GM. 1999. Defects in the germ line and gonads of mice lacking connexin43. Biol Reprod 60:1263-1270.
32. Kirby JD, Jetton AE, Cooke PS, Hess RA, Bunick D, Ackland JF, Turek FW, Schwartz NB. 1992. Developmental hormonal profiles accompanying the neonatal hypothyroidism induced increases in adult testis size and sperm production in the rat. Endocrinology 131:559-565.
33. Kumar NM, Gilula NB. 1996. The gap junction communication channel. Cell 84:381-388.
34. Laslett AL, Li LH, Jester WF Jr, Orth JM. 2000. Thyroid hormone downregulates neural cell adhesion molecule expression and affects attachment of gonocytes in Sertoli cell-gonocyte cocultures. Endocrinology 141:1633-1641.
35. Lauf U, Giepmans BN, Lopez P, Braconnot S, Chen SC, Falk MM. 2002. Dynamic trafficking and delivery of connexons to the plasma membrane and accretion to gap junctions in living cells. Proc Natl Acad Sci USA 99:10446-10451.
36. Lazar MA. 1993. Thyroid hormone receptors: Multiple forms, multiple possibilities. Endocr Rev 14:184-193.
37. Loewenstein WR, Rose B. 1992. The cell-cell channel in the control of growth. Semin Cell Biol 3:59-79.
38. Oncu M, Kavakli D, Gokcimen A, Gulle K, Orhan H, Karaoz E. 2004. Investigation on the histopathological effects of thyroidectomy on the seminiferous tubules of immature and adult rats. Urol Int 73:59-64.
39. Oppenheimer JH, Schwartz HL, Surks MI. 1974. Tissue differences in the concentration of triiodothyronine nuclear binding sites in the rat: Liver, kidney, pituitary, heart, brain, spleen, and testis. Endocrinology 95:897-903.
40. Palmero S, Maggiani S, Fugassa E. 1988. Nuclear triiodothyronine receptors in rat Sertoli cells. Mol Cell Endocrinol 58:253-256.
41. Palmero S, De Marchis M, Gallo G, Fugassa E. 1989. Thyroid hormone affects the development of Sertoli cell function in the rat. J Endocrinol 123:105-111.
42. Palmero S, Prati M, Barreca A, Minuto F, Giordano G, Fugassa E. 1990. Thyroid hormone stimulates the production of IGF-1 by rat Sertoli cells. Mol Cell Endocrinol 68:61-65.
43. Palmero S, De Marco P, Fugassa E. 1995a. Thyroid hormone receptor βmRNA expression in Sertoli cells isolated from prepubertal testis. J Mol Endocrinol 14: 131-134.
44. Palmero S, Prati M, Bolla F, Fugassa E. 1995b. Tri-iodothyronine (T3) directly affects rat Sertoli cell proliferation and differentiation. J Endocrinol 145:355-362.
45. Plum A, Hallas G, Magin T, Dombrowski F, Hagendorff A, Schumacher B, Wolpert C, Kim J, Lamers WH, Evert M, Meda P, Traub O, Willecke K. 2000. Unique and shared functions of different connexins in mice. Curr Biol 10:1083-1091.
46. Poguet AL, Legrand C, Feng X, Yen PM, Meltzer P, Samarut J, Flamant F. 2003. Microarray analysis of knockout mice identifies cyclin D2 as a possible mediator for the action of thyroid hormone during the postnatal development of the cerebellum. Dev Biol 254:188-199.
47. Risley MS, Tan IP, Roy C, Saez JC. 1992. Cell-, age- and stage-dependent distribution of connexin43 gap junctions in testes. J Cell Sci 103:81-96.
48. Rogers M, Berestecky JM, Hossain MZ, Guo HM, Kadle R, Nicholson BJ, Bertram JS. 1990. Retinoid-enhanced gap junctional communication is achieved by increased levels of connexin 43 mRNA and protein. Mol Carcinog 3:335-343.
49. Roscoe WA, Barr KJ, Mhawi AA, Pomerantz DK, Kidder GM. 2001. Failure of spermatogenesis in mice lacking connexin43. Biol Reprod 65:829-838.
50. Saint-Pierre N, Dufresne J, Rooney AA, Cyr DG. 2003. Neonatal hypothyroidism alters the localization of gap junctional protein connexin 43 in the testis and messenger RNA levels in the epididymis of the rat. Biol Reprod 68:1232-1240.
51. Sakai Y, Yamashina S, Furudate S. 2004. Developmental delay and unstable state of the testes in the rdw rat with congenital hypothyroidism. Dev Growth Differ 46:327-334.
52. Segal J. 1989. A rapid, extranuclear effect of 3,5,3′- triiodothyronine on sugar uptake by several tissues in the rat in vivo. Evidence for a physiological role for the thyroid hormone action at the level of the plasma membrane. Endocrinology 124:2755-2764.
53. Silva FR, Leite LD, Barreto KP, D'Agostini C, Zamoner A. 2001. Effect of 3,5, 3′-triiodo-L-thyronine on amino acid accumulation and membrane potential in Sertoli cells of the rat testis. Life Sci 69:977-986.
54. Sohl G, Willecke K. 2003. An update on connexin genes and their nomenclature in mouse and man. Cell Commun Adhes 10:173-180.
55. Stock A, Sies H. 2000. Thyroid hormone receptors bind to an element in the connexin43 promoter. Biol Chem 381:973-979.
56. Stock A, Sies H, Stahl W. 1998. Enhancement of gap junctional communication and connexin43 expression by thyroid hormones. Biochem Pharmacol 55:475-479.
57. Stout C, Goodenough DA, Paul DL. 2004. Connexins: Functions without junctions. Curr Opin Cell Biol 16:507-512.
58. Theiss C, Meller K. 2002. Microinjected anti-actin antibodies decrease gap junctional intercellular commmunication in cultured astrocytes. Exp Cell Res 281:197-204.
59. Tokunaga K, Taniguchi H, Yoda K, Shimizu M, Sakiyama S. 1986. Nucleotide sequence of a full-length cDNA for mouse cytoskeletal beta-actin mRNA. Nucleic Acids Res 14:2829.
60. Tribulova N, Shneyvays V, Mamedova LK, Moshel S, Zinman T, Shainberg A, Manoach M, Weismann P, Kostin S. 2004. Enhanced connexin-43 and alpha-sarcomeric actin expression in cultured heart myocytes exposed to triiodo-L-thyronine. J Mol Histol 35:463-470.
61. Van Haaster LH, de Jong FH, Docter R, de Rooij DG. 1993. High neonatal triiodothyronine levels reduce the period of Sertoli cell proliferation and accelerate tubular lumen formation in the rat testis, and increase serum inhibin levels. Endocrinology 133:755-760.
62. + channels and calcium-dependent pathways in the action of T3 on amino acid accumulation and membrane potential in Sertoli cells of immature rat testis. Life Sci 74:1277-1288.
63. Yu W, Dahl G, Werner R. 1994. The connexin43 gene is responsive to oestrogen. Proc R Soc Lond B Biol Sci 255:125-132.
64. Zamoner A, Corbelini PF, Funchal C, Menegaz D, Silva FRMB, Pessoa-Pureur R. 2005. Involvement of calcium-dependent mechanisms in T3-induced phosphorylation of vimentin of immature rat testis. Life Sci 77:3321-3335.
65. Zhang YW, Kaneda M, Morita I. 2003. The gap junction-independent tumor-suppressing effect of connexin 43. J Biol Chem 278:44852-44856.