Failure of spermatogenesis in mice lacking connexin43

Biology of Reproduction

Volumn 65, Issue 3, 2001, Pages 829-838

  Roscoe, W A ^a   Barr, K J ^a   Mhawi, A A ^a   Pomerantz, D K ^a   Kidder, G M ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Developmental biology; Gametogenesis; Leydig cells; Sertoli cells; Spermatogenesis; Testis; Testosterone

Indexed keywords

ANDROGEN; CONNEXIN 43; CYCLIC AMP; LUTEINIZING HORMONE; TESTOSTERONE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COMMUNICATION; CONTROLLED STUDY; FETUS; GENE; GENOTYPE; IMMUNOCYTOCHEMISTRY; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPERMATOGENESIS; TESTIS DEVELOPMENT;

EID: 0034883497     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod65.3.829     Document Type: Article

References (28)

1. Structure of gap junction intercellular channels
2. Connexin gene expression in seminiferous tubules of the Sprague-Dawley rat
3. Cell-, age-, and stage-dependent distribution of connexin43 gap junctions in testes
4. Characterization of gap junctions between pairs of Leydig cells from mouse testis
5. The distribution of connexin43 is associated with the germ cell differentiation and with the modulation of the Sertoli cell junctional barrier in continual (guinea pig) and seasonal breeders' (mink) testes
6. Regulated assembly of connexin33 and connexin43 into rat Sertoli cell gap junctions
7. Connexin43 gene expression and regulation in the rodent seminiferous epithelium
8. Gonocyte-Sertoli cell interactions during development of the neonatal rodent testis
9. The follicle-stimulating hormone receptor: Biochemistry, molecular biology, physiology, and pathophysiology
10. Leydig cell cooperation in vitro: Evidence for communication between adult rat Leydig cells
11. Intercellular communication between mouse Leydig cells
12. Cardiac malformation in neonatal mice lacking connexin43
13. Defects in the germ line and gonads of mice lacking connexin43
14. Development of mouse and rat oocytes in chimeric reaggregated ovaries after interspecific exchange of somatic and germ cell components
15. Intercellular communication via connexin43 gap junctions is required for ovarian folliculogenesis in the mouse
16. The effect of prenatal treatment with busulfan on in vitro androgen production by testes from rats of various ages
17. Follicular development in transplanted fetal and neonatal mouse ovaries is influenced by the gonadal status of the adult recipient
18. Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA). Structural conservation and the detection of a nucleolar form
19. Proliferation of spermatogonia and Sertoli cells in maturing mice
20. An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis
21. Regulation of Leydig cell steroidogenic function during aging
22. Transfer of second messengers through gap junction connexin43 channels reconstituted in liposomes
23. Direct isolation and analysis of endogenous transjunctional ADP from Cx43 transfected C6 glioma cells
24. Selective transfer of endogenous metabolites through gap junctions composed of different connexins
25. Unique and shared functions of different connexins in mice
26. Apoptosis regulator Bcl-w is essential for spermatogenesis but appears otherwise redundant
27. Molecular pathway of germ cell apoptosis following ischemia/reperfusion of the rat testis
28. Expression and regulation of connexin43 in rat Leydig cells