Enhanced connexin-43 and α-sarcomeric actin expression in cultured heart myocytes exposed to triiodo-L-thyronine

Journal of Molecular Histology

Volumn 35, Issue 5, 2004, Pages 463-470

  Tribulova, Narcis ^a   Shneyvays, Vladimir ^b   Mamedova, Liaman K ^b   Moshel, Shay ^b   Zinman, Tova ^b   Shainberg, Asher ^b   Manoach, Mordechai ^c   Weismann, Peter ^d   Kostin, Sawa ^e  

^a INSTITUTE OF CHEMISTRY   (Slovakia)

^b BAR ILAN UNIVERSITY   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

^d Physics and Informatics   (Slovakia)

^e MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA ACTIN; CONNEXIN 43; LIOTHYRONINE; PROTEIN ALPHA SARCOMERIC ACTIN; UNCLASSIFIED DRUG; ACTIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON MICROSCOPY; GAP JUNCTION; HEART MUSCLE CELL; IMMUNOFLUORESCENCE; MUSCLE FIBER CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SARCOMERE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; ULTRASTRUCTURE;

ANIMALIA;

ACTINS; ANIMALS; CELLS, CULTURED; CONNEXIN 43; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; MYOCYTES, CARDIAC; RATS; TRIIODOTHYRONINE;

EID: 4544226609     PISSN: 15672379     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:HIJO.0000045945.16046.b5     Document Type: Article

References (37)

1. Ascheim DD, Hryniewicz K (2002) Thyroid hormone metabolism in patients with congestive heart failure: The low triiodothyronine state. Thyroid 12: 511-515.
2. Bex V, Mercier T, Chaumontet C, Gaillard-sachez I, Flechon B, Mazet F, Traub O, Martel P (1995) Retinoic acid enhances connexin43 expression at the post-transcriptional level in rat liver epithelial cells. Cell Biochem Funct 13: 69-77.
3. Brick H, Shainberg A (1990) Thyroxine induces transition of red towards white muscle in cultured heart cells. Basic Res Cardiol 85: 237-246.
4. Burt JM, Spray DC (1988) Inotropic agents modulate gap junctional conductance between cardiac myocytes. Am J Physiol 254: H1206-H1210.
5. D'Alecy LG (1997) Thyroid hormone in neural rescue. Thyroid 7: 115-124.
6. Darrow BJ, Laing JG, Lampe PD, Saffitz JE, Beyer EC (1995) Expression of multiple connexins in cultured neonatal rat ventricular myocytes. Circ Res 76: 381-387.
7. Davis PJ, Davis FB (2002) Nongenomic actions of thyroid hormone on the heart. Thyroid 12: 459-466.
8. De Mello WC (1995) The cardiac renin-angiotensin system: Its possible role in cell communication and impulse propagation. Cardiovasc Res 29: 730-736.
9. Decker RS (1976) Hormonal regulation of gap junction differentiation. J Cell Biol 69: 669-685.
10. Dhein S (1998) Gap junction channels in the cardiovascular system: Pharmacological and physiological modulation. Trends Pharm Sci 19: 229-241.
11. Dodge SM, Beardslee MA, Darrow BJ, Green KG, Beyer EC, Saffitz JE (1998) Effect of angiotensin II on expression of the gap junction channel protein connexin43 in neonatal rat ventricular myocytes. J Am Coll Cardiol 32: 800-807.
12. Factor MA, Mayor GH, Nachreiner RF, D'Alecy LG (1993) Thyroid hormone loss and replacement during resuscitation from cardiac arrest in dogs. Resuscitation 26: 141-162.
13. Gustafson TA, Markham BE, Morkin E (1986) Effects of thyroid hormone on α-action and myosin heavy chain gene expression in cardiac and skeletal muscles of the rat. Circ Res 59: 194-201.
14. Hamilton MA, Stevenson LW, Fonarow GC, Steimle A, Goldhaber JI, Child JS, Chopra IJ, Moriguchi JD, Hage A (1998) Safety and hemodynamic effects of intravenous triiodothyronine in advanced congestive heart failure. Am J Cardiol 81: 443-447.
15. Jongsma HJ, Wilders R (2000) Gap junctions in cardiovascular disease. Circ Res 86: 1193-1197.
16. Kanno S, Saffitz JE (2001) The role of myocardial gap junctions in electrical conduction and arrhythmohenesis. Cardiovasc Pathol 10: 79-91.
17. Kaprielian RR, Gunninng M, Dupont E, Sheppard MN, Rothery SM, Underwood R, Pennel DJ, Fox K, Pepper J, Poole-Wilson PA, Severs NJ (1998) Down-regulation of immunodetectable connexin-43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle. Circulation 97: 651-660.
18. Khoury SF, Hoit BD, Dave V, Pawlosky-Dahm CM, Shao Y, Gabel M, Periasamy M, Walsh RA (1996) Effects of thyroid hormone on left ventricular performance and regulation of contractile and Ca-cycling proteins in the baboon. Circ Res 79: 727-735.
19. Kim D, Smith TW (1985) Effects of thyroid hormone on calcium handling in cultured chick ventricular cells. J Physiol 364: 131-149.
20. Klein I, Ojamaa K (2001) Thyroid hormone and the cardiovascular system. N Engl J Med 344: 501-509.
21. Kostin S, Hein S, Bauer EP, Schaper J (1999) Spatiotemporal development and distribution of intercellular junctions in adult rat cardiomyocytes in culture. Circ Res 85: 154-167.
22. Kostin S, Rieger M, Dammer S, Hein S, Richter M, Klovekorn WP, Bauer EP, Schaper J (2003) Gap junction remodeling and altered connexin43 expression in the failing human heart. Mol Cell Biochem 242: 135-144.
23. Manoach M, Netz H, Varon D, Amitzur G, Weinstock M, Kauli A, Assaeli M (1986) Factors influencing spontaneous initiation and termination of ventricular fibrillation. Jap Heart J 27: 365-375.
24. Mintz G, Pizzarello R, Klein I (1991) Enhanced left ventricular diastolic function in hyperthyroidism: noninvasive assessment and response to treatment. J Clin Endocrinol Metab 73: 146-150.
25. Morkin E (1993) Regulation of myosin heavy chain genes in the heart. Circulation 87: 1451-1460.
26. Peters NS, Coromilas J, Severs NJ, Wit AL (1997) Disturbed connexin 43 gap junction distribution correlates with location of circuits in the epicardial border zone of healing canine infarct that cause ventricular tachycardia. Circulation 95: 988-996.
27. Polontchouk L, Ebelt B, Jackels M, Dhein S (2002) Chronic effects of endothelin-1 and angiotensin II on gap junctions and intercellular communication in cardiac cells. FASEB J 16: 87-89.
28. Severs NJ (1994) Pathophysiology of gap junction in heart disease. J Cardiovasc Electrophysiol 5: 462-475.
29. Shenoy R, Klein I, Ojamaa K (2001) Differential regulation of SR calcium transporters by thyroid hormone in rat atria and ventricles. Am J Physiol 281: H1690-H1696.
30. Shneyvays V, Mamedova L, Jacobson K, Shainberg A (2001) Activation of A3 adenosine receptor protects against doxorubicin-induced cardiotoxicity. J Mol Cell Cardiol 33: 1249-1261.
31. Shneyvays V, Mamedova L, Korkus A, Shainberg A (2002) Cardiomyocyte resistance to doxorubicin mediated by A3 adenosine receptor. J Mol Cell Cardiol 34: 493-507.
32. Stagg RB, Flechter WH (1990) The hormone-induced regulation of contact-dependent cell-cell communication by phosphorylation. Endocr Rev 11: 302-305.
33. Stock A, Sies H, Stahl W (1998) Enhancement of gap junctional communication and connexin43 expression by thyroid hormones. Biochem Pharmacol 55: 475-479.
34. Stock A, Sies H (2000) Thyroid hormone receptors bind to an element in the connexin43 promoter. Biol Chem 381: 973-979.
35. +-induced lethal arrhythmias, in isolated rat heart. Exp Physiol 82: 195-205.
36. Tribulova N, Okruhlicova L, Varon D, Manoach M, Pechanova O, Bernatova I, Weismann P, Barancik M, Styk J, Slezak J (2002b) Structural substrates involved in the development of severe arrhythmias in hypertensive rat and aged guinea pig hearts. In: Dhalla N, Singal P, eds. Cardiac Remodeling and Failure. Boston, pp. 377-398.
37. Yu W, Dahl G, Werner R (1994) The connexin43 gene is responsive to oestrogen. Proc R Soc Lond B 255: 125-132.