Inhibition of caspase-9 reduces chondrocyte apoptosis and proteoglycan loss following mechanical trauma

Osteoarthritis and Cartilage

Volumn 14, Issue 10, 2006, Pages 1002-1010

  Huser, C A M ^a   Peacock, M ^a   Davies, M E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Apoptosis; Caspases; Mechanical trauma; Proteoglycans

Indexed keywords

CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE 9 INHIBITOR; GLYCOSAMINOGLYCAN; PROTEOGLYCAN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; BONE MATURATION; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL CULTURE; CELL DEATH; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ENZYME ASSAY; ENZYME INHIBITION; HORSE; IN VITRO STUDY; INCUBATION TIME; INHIBITION KINETICS; MECHANICAL STRESS; NICK END LABELING; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TIME; TISSUE CULTURE; TRANSMISSION ELECTRON MICROSCOPY; WEIGHT BEARING; WEIGHT GAIN;

ANIMALS; APOPTOSIS; CARTILAGE, ARTICULAR; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CHONDROCYTES; GLYCOSAMINOGLYCANS; HORSES; IN SITU NICK-END LABELING; MICROSCOPY, ELECTRON, TRANSMISSION; PROTEOGLYCANS; WEIGHT GAIN;

EID: 33748186967     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2006.03.012     Document Type: Article

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