메뉴 건너뛰기




Volumn 9, Issue 1, 1997, Pages 107-113

Regulation of transcription of MHC class II genes

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 0031050035     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0952-7915(97)80166-5     Document Type: Article
Times cited : (184)

References (57)
  • 1
    • 0023886025 scopus 로고
    • Human class II major histocompatibility complex genes and proteins
    • Kappes D, Strominger JL. Human class II major histocompatibility complex genes and proteins. Annu Rev Biochem. 57:1988;991-1028.
    • (1988) Annu Rev Biochem , vol.57 , pp. 991-1028
    • Kappes, D.1    Strominger, J.L.2
  • 5
    • 0028842529 scopus 로고
    • IFN-β acts downstream of IFN-induced CIITA mRNA accumulation to block MHC class II gene expression and requires the 48 kD DNA binding protein, ISGF3-γ
    • of special interest. Describes additional level of class II expression that occurs in the presence of the essential MHC class II regulatory factor CIITA. Previous work had suggested that MHC class expression was limited solely by CIITA.
    • Lu H-T, Riley JL, Babcock GT, Huston M, Stark GR, Boss JM, Ransohoff RM. IFN-β acts downstream of IFN-induced CIITA mRNA accumulation to block MHC class II gene expression and requires the 48 kD DNA binding protein, ISGF3-γ of special interest J Exp Med. 182:1995;1517-1525 Describes additional level of class II expression that occurs in the presence of the essential MHC class II regulatory factor CIITA. Previous work had suggested that MHC class expression was limited solely by CIITA.
    • (1995) J Exp Med , vol.182 , pp. 1517-1525
    • Lu, H.-T.1    Riley, J.L.2    Babcock, G.T.3    Huston, M.4    Stark, G.R.5    Boss, J.M.6    Ransohoff, R.M.7
  • 6
    • 0027378549 scopus 로고
    • Transforming growth factor-β1 repression of the HLA-DRα gene is mediated by conserved proximal promoter elements
    • Reimold AM, Kara CJ, Rooney JW, Glimcher LH. Transforming growth factor-β1 repression of the HLA-DRα gene is mediated by conserved proximal promoter elements. J Immunol. 151:1993;4173-4182.
    • (1993) J Immunol , vol.151 , pp. 4173-4182
    • Reimold, A.M.1    Kara, C.J.2    Rooney, J.W.3    Glimcher, L.H.4
  • 7
    • 0027442671 scopus 로고
    • Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-induced expression
    • Brown AM, Wright KL, Ting JP-Y. Human major histocompatibility complex class II-associated invariant chain gene promoter. Functional analysis and in vivo protein/DNA interactions of constitutive and IFN-induced expression. J Biol Chem. 268:1993;26328-26333.
    • (1993) J Biol Chem , vol.268 , pp. 26328-26333
    • Brown, A.M.1    Wright, K.L.2    Ting, J.-Y.3
  • 8
    • 0029132892 scopus 로고    scopus 로고
    • The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes
    • Kern I, Steimle V, Siegrist C, Mach B. The two novel MHC class II transactivators RFX5 and CIITA both control expression of HLA-DM genes. Int Immunol. 7:1996;1295-1299.
    • (1996) Int Immunol , vol.7 , pp. 1295-1299
    • Kern, I.1    Steimle, V.2    Siegrist, C.3    Mach, B.4
  • 9
    • 0028924986 scopus 로고
    • Class II transactivator regulates the expression of multiple genes involved in antigen presentation
    • Chang C-H, Flavell RA. Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J Exp Med. 181:1995;765-767.
    • (1995) J Exp Med , vol.181 , pp. 765-767
    • Chang, C.-H.1    Flavell, R.A.2
  • 10
    • 0024518769 scopus 로고
    • Combined immunodeficiency with defective expression in MHC class II genes
    • Griscelli C, Lisowska Grospierre B, Mach B. Combined immunodeficiency with defective expression in MHC class II genes. Immunodefic Rev. 1:1989;135-153.
    • (1989) Immunodefic Rev , vol.1 , pp. 135-153
    • Griscelli, C.1    Lisowska Grospierre, B.2    Mach, B.3
  • 11
    • 0025762568 scopus 로고
    • Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis
    • Benichou B, Strominger JL. Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis. Proc Natl Acad Sci USA. 88:1991;4285-4288.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4285-4288
    • Benichou, B.1    Strominger, J.L.2
  • 12
    • 0026556640 scopus 로고
    • Genetic complexity of regulatory mutants defective for HLA class II expression
    • Seidl C, Saraiya C, Osterweil Z, Fu YP, Lee JS. Genetic complexity of regulatory mutants defective for HLA class II expression. J Immunol. 148:1992;1576-1584.
    • (1992) J Immunol , vol.148 , pp. 1576-1584
    • Seidl, C.1    Saraiya, C.2    Osterweil, Z.3    Fu, Y.P.4    Lee, J.S.5
  • 13
    • 0026587777 scopus 로고
    • Single base pair substitutions within the HLA-DRA gene promoter separate the functions of the X1 and X2 boxes
    • Sloan JH, Hasegawa SL, Boss JM. Single base pair substitutions within the HLA-DRA gene promoter separate the functions of the X1 and X2 boxes. J Immunol. 148:1992;2591-2599.
    • (1992) J Immunol , vol.148 , pp. 2591-2599
    • Sloan, J.H.1    Hasegawa, S.L.2    Boss, J.M.3
  • 14
    • 0024290444 scopus 로고
    • Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X
    • Reith W, Satola S, Herreo-Sanchez C, Amaldi I, Lisowska-Grospierre B, Griscelli C, Hadam MR, Mach B. Congenital immunodeficiency with a regulatory defect in MHC class II gene expression lacks a specific HLA-DR promoter binding protein, RF-X. Cell. 53:1988;897-906.
    • (1988) Cell , vol.53 , pp. 897-906
    • Reith, W.1    Satola, S.2    Herreo-Sanchez, C.3    Amaldi, I.4    Lisowska-Grospierre, B.5    Griscelli, C.6    Hadam, M.R.7    Mach, B.8
  • 15
    • 0027256459 scopus 로고
    • Protease treatment of nuclear extracts distinguishes between class II major histocompatibility complex X1 box DNA-binding proteins in wild type and class II deficient B cells
    • Hasegawa SL, Riley JL, Sloan JH, Boss JM. Protease treatment of nuclear extracts distinguishes between class II major histocompatibility complex X1 box DNA-binding proteins in wild type and class II deficient B cells. J Immunol. 150:1993;1781-1793.
    • (1993) J Immunol , vol.150 , pp. 1781-1793
    • Hasegawa, S.L.1    Riley, J.L.2    Sloan, J.H.3    Boss, J.M.4
  • 16
    • 0026665461 scopus 로고
    • The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters
    • Herrero-Sanchez C, Reith W, Silacci P, Mach B. The DNA-binding defect observed in major histocompatibility complex class II regulatory mutants concerns only one member of a family of complexes binding to the X boxes of class II promoters. Mol Cell Biol. 12:1992;4076-4083.
    • (1992) Mol Cell Biol , vol.12 , pp. 4076-4083
    • Herrero-Sanchez, C.1    Reith, W.2    Silacci, P.3    Mach, B.4
  • 17
    • 0027994698 scopus 로고
    • Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX
    • Durand B, Kobr M, Reith W, Mach B. Functional complementation of major histocompatibility complex class II regulatory mutants by the purified X-box-binding protein RFX. Mol Cell Biol. 14:1994;6839-6847.
    • (1994) Mol Cell Biol , vol.14 , pp. 6839-6847
    • Durand, B.1    Kobr, M.2    Reith, W.3    Mach, B.4
  • 18
    • 11944266638 scopus 로고
    • A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome)
    • of outstanding interest. This paper describes the cloning of a gene (RFX5) encodong one of the subunits of RFX. Mutations in RFX5 are responsible for some, but not all, of the cases of the bare lymphocyte syndrome.
    • Steimle V, Durand B, Emmanuele B, Zufferey M, Hadam MR, Mach B, Reith W. A novel DNA-binding regulatory factor is mutated in primary MHC class II deficiency (bare lymphocyte syndrome). of outstanding interest Genes Dev. 9:1995;1021-1032 This paper describes the cloning of a gene (RFX5) encodong one of the subunits of RFX. Mutations in RFX5 are responsible for some, but not all, of the cases of the bare lymphocyte syndrome.
    • (1995) Genes Dev , vol.9 , pp. 1021-1032
    • Steimle, V.1    Durand, B.2    Emmanuele, B.3    Zufferey, M.4    Hadam, M.R.5    Mach, B.6    Reith, W.7
  • 19
    • 0029997190 scopus 로고    scopus 로고
    • RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom
    • of special interest. The molecular basis for the similarity of the RFX family of proteins is presented. This similarity shows that the RFX DNA binding domain is a common structure motif that is utilized across species.
    • Emery P, Durand B, Mach B, Reith W. RFX proteins, a novel family of DNA binding proteins conserved in the eukaryotic kingdom. of special interest Nucleic Acids Res. 24:1996;307-803 The molecular basis for the similarity of the RFX family of proteins is presented. This similarity shows that the RFX DNA binding domain is a common structure motif that is utilized across species.
    • (1996) Nucleic Acids Res , vol.24 , pp. 307-803
    • Emery, P.1    Durand, B.2    Mach, B.3    Reith, W.4
  • 20
    • 0026734795 scopus 로고
    • Sequences and factors: A guide to MHC class II transcription
    • W.E. Paul, C. Garrision Fathman, Metzger H. Palo Alto: Annual Reviews Inc
    • Glimcher LH, Kara CJ. Sequences and factors: a guide to MHC class II transcription. Paul WE, Garrision Fathman C, Metzger H. Annual Reviews of Immunology. 1992;13-50 Annual Reviews Inc, Palo Alto.
    • (1992) Annual Reviews of Immunology , pp. 13-50
    • Glimcher, L.H.1    Kara, C.J.2
  • 21
    • 0025938888 scopus 로고
    • Two distinct B cell factors bind the HLA-DRA X box region and recognize different subsets of MHC class II promoters
    • Hasegawa SL, Boss JM. Two distinct B cell factors bind the HLA-DRA X box region and recognize different subsets of MHC class II promoters. Nucleic Acids Res. 19:1991;6269-6276.
    • (1991) Nucleic Acids Res , vol.19 , pp. 6269-6276
    • Hasegawa, S.L.1    Boss, J.M.2
  • 22
    • 0028804166 scopus 로고
    • Purified X2BP cooperatively binds the class II MHC X box region in the presence of purified RFX the X box factor deficient in the bare lymphocyte syndrome
    • of special interest. Defines X2BP as the X2 box factor by showing cooperative interactions with RFX and X box DNA.
    • Moreno CS, Emery P, West JE, Durand B, Reith W, Mach B, Boss JM. Purified X2BP cooperatively binds the class II MHC X box region in the presence of purified RFX the X box factor deficient in the bare lymphocyte syndrome. of special interest J Immunol. 155:1995;4313-4321 Defines X2BP as the X2 box factor by showing cooperative interactions with RFX and X box DNA.
    • (1995) J Immunol , vol.155 , pp. 4313-4321
    • Moreno, C.S.1    Emery, P.2    West, J.E.3    Durand, B.4    Reith, W.5    Mach, B.6    Boss, J.M.7
  • 23
    • 0027998318 scopus 로고
    • Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters
    • Reith W, Kobr M, Emery P, Durand B, Siegrist C-A, Mach B. Cooperative binding between factors RFX and X2bp to the X and X2 boxes of MHC class II promoters. J Biol Chem. 269:1994;20020-20025.
    • (1994) J Biol Chem , vol.269 , pp. 20020-20025
    • Reith, W.1    Kobr, M.2    Emery, P.3    Durand, B.4    Siegrist, C.-A.5    Mach, B.6
  • 24
    • 0025787609 scopus 로고
    • Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements
    • Ivashkiv LB, Glimcher LH. Repression of class II major histocompatibility complex genes by cyclic AMP is mediated by conserved promoter elements. J Exp Med. 174:1991;1583-1592.
    • (1991) J Exp Med , vol.174 , pp. 1583-1592
    • Ivashkiv, L.B.1    Glimcher, L.H.2
  • 25
    • 0028920041 scopus 로고
    • Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3
    • Sinha S, Maity SN, Lu J, De Crombrugghe B. Recombinant rat CBF-C, the third subunit of CBF/NFY, allows formation of a protein-DNA complex with CBF-A and CBF-B and with yeast HAP2 and HAP3. Proc Natl Acad Sci USA. 92:1995;1624-1628.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1624-1628
    • Sinha, S.1    Maity, S.N.2    Lu, J.3    De Crombrugghe, B.4
  • 26
    • 0028883954 scopus 로고
    • CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA
    • Ronchi A, Bellorini M, Mongelli N, Mantovani R. CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA. Nucleic Acids Res. 23:1995;4565-4572.
    • (1995) Nucleic Acids Res , vol.23 , pp. 4565-4572
    • Ronchi, A.1    Bellorini, M.2    Mongelli, N.3    Mantovani, R.4
  • 27
    • 0026081823 scopus 로고
    • Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene
    • Zeleznik-Le NJ, Azizkhan JC, Ting JP-Y. Affinity-purified CCAAT-box-binding protein (YEBP) functionally regulates expression of a human class II major histocompatibility complex gene and the herpes simplex virus thymidine kinase gene. Proc Natl Acad Sci USA. 88:1991;1873-1877.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 1873-1877
    • Zeleznik-Le, N.J.1    Azizkhan, J.C.2    Ting, J.-Y.3
  • 28
    • 0028054792 scopus 로고
    • Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y
    • Reith W, Siegrist CA, Durand B, Barras E, Mach B. Function of major histocompatibility complex class II promoters requires cooperative binding between factors RFX and NF-Y. Proc Natl Acad Sci USA. 91:1994;554-558.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 554-558
    • Reith, W.1    Siegrist, C.A.2    Durand, B.3    Barras, E.4    Mach, B.5
  • 29
    • 0028876195 scopus 로고
    • Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes
    • Reith W, Steimle V, Mach B. Molecular defects in the bare lymphocyte syndrome and regulation of MHC class II genes. Immunol Today. 16:1995;539-546.
    • (1995) Immunol Today , vol.16 , pp. 539-546
    • Reith, W.1    Steimle, V.2    Mach, B.3
  • 30
    • 0026316475 scopus 로고
    • Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function
    • Vilen BJ, Cogswell JP, Ting JP-Y. Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Mol Cell Biol. 11:1991;2406-2415.
    • (1991) Mol Cell Biol , vol.11 , pp. 2406-2415
    • Vilen, B.J.1    Cogswell, J.P.2    Ting, J.-Y.3
  • 31
    • 0029617947 scopus 로고
    • Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome
    • Thanos D, Maniatis T. Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome. Cell. 83:1995;1091-1100.
    • (1995) Cell , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 32
    • 0025120331 scopus 로고
    • Mutational analysis of the DRA promoter: Cis-acting sequences and trans-acting factors
    • Tsang SY, Nakanishi M, Peterlin BM. Mutational analysis of the DRA promoter: cis-acting sequences and trans-acting factors. Mol Cell Biol. 10:1990;711-719.
    • (1990) Mol Cell Biol , vol.10 , pp. 711-719
    • Tsang, S.Y.1    Nakanishi, M.2    Peterlin, B.M.3
  • 33
    • 0027057979 scopus 로고
    • Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-inducible expression of the HLA-DRA gene
    • Vilen BJ, Penta JF, Ting JP-Y. Structural constraints within a trimeric transcriptional regulatory region. Constitutive and interferon-inducible expression of the HLA-DRA gene. J Biol Chem. 267:1992;23728-23734.
    • (1992) J Biol Chem , vol.267 , pp. 23728-23734
    • Vilen, B.J.1    Penta, J.F.2    Ting, J.-Y.3
  • 34
    • 0029762163 scopus 로고    scopus 로고
    • Complex architecture of major histocompatibility complex class II promoters: Reiterated motifs and conserved protein-protein interactions
    • Jabrane-Ferrat N, Fontes JD, Boss JM, Peterlin BM. Complex architecture of major histocompatibility complex class II promoters: reiterated motifs and conserved protein-protein interactions. Mol Cell Biol. 16:1996;4683-4690.
    • (1996) Mol Cell Biol , vol.16 , pp. 4683-4690
    • Jabrane-Ferrat, N.1    Fontes, J.D.2    Boss, J.M.3    Peterlin, B.M.4
  • 35
    • 0025870067 scopus 로고
    • In vivo footprinting of MHC class II genes: Bare promoters in the bare lymphocyte syndrome
    • Kara CJ, Glimcher LH. In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome. Science. 252:1991;709-712.
    • (1991) Science , vol.252 , pp. 709-712
    • Kara, C.J.1    Glimcher, L.H.2
  • 36
    • 0027131208 scopus 로고
    • Class II MHC transcriptional mutants are defective in higher order complex formation
    • Riley JL, Boss JM. Class II MHC transcriptional mutants are defective in higher order complex formation. J Immunol. 151:1993;6942-6953.
    • (1993) J Immunol , vol.151 , pp. 6942-6953
    • Riley, J.L.1    Boss, J.M.2
  • 37
    • 0027490172 scopus 로고
    • Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (bare lymphocyte syndrome)
    • Steimle V, Otten LA, Zufferey M, Mach B. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (bare lymphocyte syndrome). Cell. 75:1993;135-146.
    • (1993) Cell , vol.75 , pp. 135-146
    • Steimle, V.1    Otten, L.A.2    Zufferey, M.3    Mach, B.4
  • 38
    • 0029048828 scopus 로고
    • Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA)
    • of special interest. A functional characterization of CIITA is presented. CIITA was found to possess a strong transcriptional activation domain, suggesting that it may regulate class II genes as a transcriptional co-activator by interacting with factors bound to the X box region.
    • Riley JL, Westerheide SD, Price JA, Brown JA, Boss JM. Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA). of special interest Immunity. 2:1995;533-543 A functional characterization of CIITA is presented. CIITA was found to possess a strong transcriptional activation domain, suggesting that it may regulate class II genes as a transcriptional co-activator by interacting with factors bound to the X box region.
    • (1995) Immunity , vol.2 , pp. 533-543
    • Riley, J.L.1    Westerheide, S.D.2    Price, J.A.3    Brown, J.A.4    Boss, J.M.5
  • 39
    • 0029075521 scopus 로고
    • Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency
    • of special interest. See annotation [38].
    • Zhou H, Glimcher LH. Human MHC class II gene transcription directed by the carboxyl terminus of CIITA, one of the defective genes in type II MHC combined immune deficiency. of special interest Immunity. 2:1995;545-553 See annotation [38].
    • (1995) Immunity , vol.2 , pp. 545-553
    • Zhou, H.1    Glimcher, L.H.2
  • 40
    • 0028041568 scopus 로고
    • Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
    • Chang C-H, Fontes JD, Peterlin BM, Flavell RA. Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. J Exp Med. 180:1994;1367-1374.
    • (1994) J Exp Med , vol.180 , pp. 1367-1374
    • Chang, C.-H.1    Fontes, J.D.2    Peterlin, B.M.3    Flavell, R.A.4
  • 41
    • 0028142430 scopus 로고
    • Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA
    • Steimle V, Siegrist C-A, Mottet A, Lisowska-Grospierre B, Mach B. Regulation of MHC class II expression by interferon-γ mediated by the transactivator gene CIITA. Science. 265:1994;106-108.
    • (1994) Science , vol.265 , pp. 106-108
    • Steimle, V.1    Siegrist, C.-A.2    Mottet, A.3    Lisowska-Grospierre, B.4    Mach, B.5
  • 42
    • 0028535402 scopus 로고
    • Molecular analysis of G1B and G3A IFN-γ mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction
    • Chin K-C, Mao C, Skinner C, Riley JL, Wright KL, Moreno CS, Stark GR, Boss JM, Ting JP-Y. Molecular analysis of G1B and G3A IFN-γ mutants reveals that defects in CIITA or RFX result in defective class II MHC and Ii gene induction. Immunity. 1:1994;687-697.
    • (1994) Immunity , vol.1 , pp. 687-697
    • Chin, K.-C.1    Mao, C.2    Skinner, C.3    Riley, J.L.4    Wright, K.L.5    Moreno, C.S.6    Stark, G.R.7    Boss, J.M.8    Ting, J.-Y.9
  • 43
    • 0343344302 scopus 로고    scopus 로고
    • Transforming growth factor-β supresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator mRNA expression
    • in press
    • Lee YJ, Lu HT, Nguyen V, Qin H, Howe PH, Rogers E, Boss JM, Ransohoff RM, Benveniste EN. Transforming growth factor-β supresses IFN-γ induction of class II MHC gene expression by inhibiting class II transactivator mRNA expression. J Immunol. 1996;. in press.
    • (1996) J Immunol
    • Lee, Y.J.1    Lu, H.T.2    Nguyen, V.3    Qin, H.4    Howe, P.H.5    Rogers, E.6    Boss, J.M.7    Ransohoff, R.M.8    Benveniste, E.N.9
  • 44
    • 0028071614 scopus 로고
    • Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA
    • Silacci P, Mottet A, Steimle V, Reith W, Mach B. Developmental extinction of major histocompatibility complex class II gene expression in plasmocytes is mediated by silencing of the transactivator gene CIITA. J Exp Med. 180:1994;1329-1336.
    • (1994) J Exp Med , vol.180 , pp. 1329-1336
    • Silacci, P.1    Mottet, A.2    Steimle, V.3    Reith, W.4    Mach, B.5
  • 46
    • 0029656184 scopus 로고    scopus 로고
    • The function of the octamer-binding site in the DRA promoter
    • Voliva CF, Jabrane-Ferrat N, Peterlin BM. The function of the octamer-binding site in the DRA promoter. Immunogenetics. 43:1996;20-26.
    • (1996) Immunogenetics , vol.43 , pp. 20-26
    • Voliva, C.F.1    Jabrane-Ferrat, N.2    Peterlin, B.M.3
  • 47
    • 0026639924 scopus 로고
    • In vivo footprint analysis of the HLA-DRA gene promoter: Cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma
    • Wright KL, Ting JP-Y. In vivo footprint analysis of the HLA-DRA gene promoter: cell-specific interaction at the octamer site and up-regulation of X box binding by interferon gamma. Proc Natl Acad Sci USA. 89:1992;7601-7605.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7601-7605
    • Wright, K.L.1    Ting, J.-Y.2
  • 48
    • 0029094903 scopus 로고
    • Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression
    • Abdulkadir SA, Krishna S, Thanos D, Maniatis T, Strominger JL, Ono SJ. Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression. J Exp Med. 182:1995;487-500.
    • (1995) J Exp Med , vol.182 , pp. 487-500
    • Abdulkadir, S.A.1    Krishna, S.2    Thanos, D.3    Maniatis, T.4    Strominger, J.L.5    Ono, S.J.6
  • 49
    • 0023813871 scopus 로고
    • Transcription of HLA class II genes in the absence of B-cell-specific octamer-binding factor
    • Stimac E, Lyons S, Pious D. Transcription of HLA class II genes in the absence of B-cell-specific octamer-binding factor. Mol Cell Biol. 8:1988;3734-3739.
    • (1988) Mol Cell Biol , vol.8 , pp. 3734-3739
    • Stimac, E.1    Lyons, S.2    Pious, D.3
  • 50
    • 0027999417 scopus 로고
    • The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms
    • Du W, Maniatis T. The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms. Proc Natl Acad Sci USA. 91:1994;11318-11322.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 11318-11322
    • Du, W.1    Maniatis, T.2
  • 51
    • 0026489365 scopus 로고
    • The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene
    • Thanos D, Maniatis T. The high mobility group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell. 71:1992;777-789.
    • (1992) Cell , vol.71 , pp. 777-789
    • Thanos, D.1    Maniatis, T.2
  • 53
    • 0028842156 scopus 로고
    • OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins
    • Stubin M, Newell JW, Matthias P. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins. Cell. 80:1995;497-506.
    • (1995) Cell , vol.80 , pp. 497-506
    • Stubin, M.1    Newell, J.W.2    Matthias, P.3
  • 54
    • 0030008916 scopus 로고    scopus 로고
    • Binding and cooperative interactions between two B cell-specific transcriptional coactivators
    • of outstanding interest. Describes first direct interactions of CIITA with another protein, Bob1, another transcriptional activator. The results of this paper suggest that multiple transcriptional co-activators may be required for maximal class II expression.
    • Fontes JD, Jabrane-Ferrat N, Toth CR, Peterlin BM. Binding and cooperative interactions between two B cell-specific transcriptional coactivators. of outstanding interest J Exp Med. 183:1996;2517-2521 Describes first direct interactions of CIITA with another protein, Bob1, another transcriptional activator. The results of this paper suggest that multiple transcriptional co-activators may be required for maximal class II expression.
    • (1996) J Exp Med , vol.183 , pp. 2517-2521
    • Fontes, J.D.1    Jabrane-Ferrat, N.2    Toth, C.R.3    Peterlin, B.M.4
  • 55
    • 0029655910 scopus 로고
    • Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5
    • Brown JA, He X-F, Westerheide SD, Boss JM. Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5. Immunogenetics. 43:1995;88-91.
    • (1995) Immunogenetics , vol.43 , pp. 88-91
    • Brown, J.A.1    He, X.-F.2    Westerheide, S.D.3    Boss, J.M.4
  • 56
    • 0029968925 scopus 로고    scopus 로고
    • Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression
    • of outstanding interest. Knockout of CIITA in mice results in a similar phenotype to BLS patients. Also, low levels of class II expression in thymus epithelium were evident, suggesting the possibility of an alternative CIITA independent mechanism of regulation.
    • Chang C, Guerder S, Hong S, Van Ewijk W, Flavell R. Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression. of outstanding interest Immunity. 4:1996;167-178 Knockout of CIITA in mice results in a similar phenotype to BLS patients. Also, low levels of class II expression in thymus epithelium were evident, suggesting the possibility of an alternative CIITA independent mechanism of regulation.
    • (1996) Immunity , vol.4 , pp. 167-178
    • Chang, C.1    Guerder, S.2    Hong, S.3    Van Ewijk, W.4    Flavell, R.5
  • 57
    • 0030002887 scopus 로고    scopus 로고
    • Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D α and β chains
    • of special interest. A novel mutation in class II gene regulation in which genes oriented in one direction on the chromosome are not expressed is described. Understanding this mutation may tie the effects of chromatin assembly and class II regulation together.
    • Douhan J III, Hauber I, Eibl MM, Glimcher LH. Genetic evidence for a new type of major histocompatibility complex class II combined immunodeficiency characterized by a dyscoordinate regulation of HLA-D α and β chains. of special interest J Exp Med. 183:1996;1063-1069 A novel mutation in class II gene regulation in which genes oriented in one direction on the chromosome are not expressed is described. Understanding this mutation may tie the effects of chromatin assembly and class II regulation together.
    • (1996) J Exp Med , vol.183 , pp. 1063-1069
    • Douhan J. III1    Hauber, I.2    Eibl, M.M.3    Glimcher, L.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.