Huntingtin's critical cleavage

Nature Neuroscience

Volumn 9, Issue 9, 2006, Pages 1088-1089

  Fryer, John D ^a   Zoghbi, Huda Y ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 6; HUNTINGTIN; POLYGLUTAMINE;

BEHAVIOR DISORDER; EXCITOTOXICITY; HUMAN; HUNTINGTON CHOREA; MUTATION; NERVE DEGENERATION; NEUROPATHOLOGY; NEUROTOXICITY; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN ISOLATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SHORT SURVEY;

ANIMALS; CASPASE 6; CASPASES; CATALYTIC DOMAIN; HUMANS; HUNTINGTON DISEASE; MICE; MICE, TRANSGENIC; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; TRINUCLEOTIDE REPEATS;

EID: 33748101722     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn0906-1088     Document Type: Short Survey

References (15)

1. Graham, R.K. et al. Cell 125, 1179-1191 (2006).
2. Gatchel, J.R. & Zoghbi, H.Y. Nat. Rev. Genet. 6, 743-755 (2005).
3. Ikeda, H. et al. Nat. Genet. 13, 196-202 (1996).
4. Emamian, E.S. et al. Neuron 38, 375-387 (2003).
5. Steffan, J.S. et al. Science 304, 100-104 (2004).
6. Takeyama, K. et al. Neuron 35, 855-864 (2002).
7. Tsuda, H. et al. Cell 122, 633-644 (2005).
8. Kim, Y.J. et al. Proc. Natl. Acad. Sci. USA 98, 12784-12789 (2001).
9. Graham, R.K. et al. Neurobiol. Dis. 21, 444-455 (2006).
10. Van Raamsdonk, J.M. et al. Hum. Mol. Genet. 14, 3823-3835 (2005).
11. Klement, I.A. et al. Cell 95, 41-53 (1998).
12. Saudou, F., Finkbeiner, S., Devys, D. & Greenberg, M.E. Cell 95, 55-66 (1998).
13. Hodgson, J.G. et al. Hum. Mol. Genet. 5, 1875-1885 (1996).
14. Leavitt, B.R. et al. J. Neurochem. 96, 1121-1129 (2006).
15. Goehler, H. et al. Mol. Cell 15, 853-865 (2004).