Protease analysis by neoepitope approach reveals the activation of MMP-9 is achieved proteolytically in a test tissue cartilage model involved in bone formation

Journal of Histochemistry and Cytochemistry

Volumn 54, Issue 9, 2006, Pages 965-980

  Lee, Eunice R ^a,b   Lamplugh, Lisa ^a   Kluczyk, Beata ^a   Mort, John S ^a,b   Leblond, Charles Philippe ^a,b  

^a SHRINERS HOSPITAL FOR CHILDREN   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Bone growth and development; Cartilage canals; Cartilage resorption; Gelatinase B; Immunohistochemistry; Matrix metalloproteinases; MMP activation; MMP 9; Neoepitope antibodies

Indexed keywords

CYSTEINE; EPITOPE; GELATINASE B; MATRIX METALLOPROTEINASE; PROTEINASE;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARTILAGE; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; EXTRACELLULAR MATRIX; FROZEN SECTION; MICROSCOPY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; RAT;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; BONE DEVELOPMENT; CARTILAGE; CELL LINE, TUMOR; CYSTEINE; ENZYME ACTIVATION; EPIPHYSES; EPITOPES; HUMANS; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; MATRIX METALLOPROTEINASE 9; MICE; MICROSCOPY, ELECTRON; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 33748092372     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1051/jp4:2006134147     Document Type: Article

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