Identification of residues critical for Cu2+-mediated inhibition of glycine α1 receptors

Neuropharmacology

Volumn 51, Issue 4, 2006, Pages 701-708

  Chen, Zhenglan ^a   Dillon, Glenn H ^a   Huang, Renqi ^a  

^a UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

Cu2+ modulation; Glycine receptor; Histidine; MTSET; Site direct mutagenesis; Zinc

Indexed keywords

CUPRIC ION; GLYCINE RECEPTOR; ZINC;

ARTICLE; BINDING SITE; CONTROLLED STUDY; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; PRIORITY JOURNAL; RECEPTOR BINDING; WILD TYPE;

CELL LINE, TRANSFORMED; CLONING, MOLECULAR; COPPER; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; GLYCINE; HISTIDINE; HUMANS; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIALS; MESYLATES; MUTAGENESIS; PATCH-CLAMP TECHNIQUES; RECEPTORS, GLYCINE; SULFHYDRYL REAGENTS; TRANSFECTION; ZINC;

EID: 33747843716     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.05.009     Document Type: Article

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