Neurokinin-1 receptor in the basolateral nuclear group of the canine amygdala-Comparative study in normal and aggressive dogs

Brain Research

Volumn 1098, Issue 1, 2006, Pages 106-112

  Jacobs, C ^a   Van Den Broeck, W ^a   Simoens, P ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Amygdala; Basolateral nuclear group; Canine aggression; Neurokinin 1 receptor; Substance P

Indexed keywords

NEUROKININ 1 RECEPTOR;

AGGRESSION; AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DENSITY; CONTROLLED STUDY; NERVE CELL NETWORK; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STATISTICAL SIGNIFICANCE;

AGGRESSION; AMYGDALA; ANIMALS; CELL COUNT; DOGS; IMMUNOHISTOCHEMISTRY; RECEPTORS, NEUROKININ-1; RNA, MESSENGER; TEMPORAL LOBE; TISSUE FIXATION;

CANIS FAMILIARIS;

EID: 33747805267     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.04.099     Document Type: Article

References (33)

1. Badsberg Samuelsen G., Bogdanović N., Laursen H., Graem N., FalckLarsen J., and Pakkenberg B. Total cell number in fetal brain. Image Anal. Stereol. 19 (2000) 35-38
2. Blier P., Gobbi G., Haddjeri N., Santarelli L., Mathew G., and Hen R. Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response. J. Psychiatry Neurosci. 29 (2004) 208-218
3. Bondy B., Baghai T.C., Minov C., Schüle C., Schwarz M.J., Zwanzger P., Rupprecht R., and Möller H.-J. Substance P serum levels are increased in major depression: preliminary results. Soc. Biol. Psychiatry 53 (2003) 538-542
4. Caberlotto L., Hurd Y.L., Murdock P., Wahlin J.P., Melotto S., Corsi M., and Carletti R. Neurokinin 1 receptor and relative abundance of the short and long isoforms in the human brain. Eur. J. Neurosci. 17 (2003) 1736-1746
5. De Felipe C., Herrero J.F., O'Brien J.A., Palmer J.A., Doyle C.A., Smith A.J.H., Laird J.M.A., Belmonte C., Cervero F., and Hunt S.P. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 392 (1998) 394-397
6. Deuschle M., Sander P., Herpfer I., Fiebich B.L., Heuser I., and Lieb K. Substance P in serum and cerebrospinal fluid of depressed patients: no effect of antidepressant treatment. Psychiatry Res. 136 (2005) 1-6
7. Dorph-Petersen K.A., Nyengaard J.R., and Gundersen H.J.G. Tissue shrinkage and unbiased stereological estimation of particle number and size. J. Microsc. 204 (2000) 232-246
8. File S.E. NKP608, an NK1 receptor antagonist, has an anxiolytic action in the social interaction test in rats. Psychopharmacology 152 (2000) 105-109
9. Gadd C.A., Murtra P., De Felipe C.D., and Hunt S.P. Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse. J. Neurosci. 10 (2003) 8271-8280
10. Gregg T.R., and Siegel A. Brain structures and neurotransmitters regulating aggression in cats: implications for human aggression. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 25 (2001) 91-140
11. Gundersen H.J.G., Bagger P., Bendtsen T.F., Evans S.M., Korbo L., Marcussen N., Møller A., Nielsen K., Nyengaard J.R., Pakkenberg B., Sørensen F.B., Vesterby A., and West M.J. The new stereological tools: dissector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Acta Pathol. Microbiol. Immunol. Scand. 96 (1988) 857-881
12. Herpfer I., and Lieb K. Substance P receptor antagonists in psychiatry. CNS Drugs 19 (2005) 275-293
13. Jacobs C., De Keuster T., and Simoens P. Assessing the pathological extent of aggressive behaviour in dogs-A review of the literature. Vet. Q. 25 (2003) 53-60
14. Jacobs C., Van Den Broeck W., and Simoens P. Quantification of neurons expressing androgen receptor and volume estimation of the basolateral nuclear group of the canine amygdaloid body. Brain Res. Protoc. 15 (2005) 92-104
15. Jacobs C., Van Den Broeck W., and Simoens P. Increased volume and neuronal number of the basolateral nuclear group of the amygdaloid body in aggressive dogs. Behav. Brain Res. 170 (2006) 119-125
16. Kramer M.S., Winokur A., Kelsey J., Preskorn S.H., Rothschild A.J., Snavely D., Ghosh K., Ball W.A., Reines S.A., Munjack D., Apter J.T., Cunningham L., Kling M., Bari M., Getson A., and Lee Y. Demonstration of the efficacy and safety of a novel substance P (NK1) receptor antagonist in major depression. Neuropsychopharmacology 29 (2004) 385-392
17. Ljungdahl A., Hökfelt T., and Nilsson G. Distribution of substance P-like immunoreactivity in the central nervous system of the rat: I. Cell bodies and nerve terminals. Neuroscience 3 (1978) 861-943
18. Mantyh P.W. Neurobiology of substance P and the NK1 receptor. J. Clin. Psychiatry 63 Suppl. 11 (2002) 6-10
19. Mantyh P.W., Gates T., Mantyh C.R., and Maggio J.E. Autoradiographic localization and characterisation of tachykinin receptor binding sites in the rat brain and peripheral tissues. J. Neurosci. 9 (1989) 258-279
20. Maubach K.A., Martin K., Smith D.W., Hewson L., Frankshun R.A., Harrison T., and Seabrook G.R. Substance P stimulates inhibitory synaptic transmission in the guinea pig basolateral amygdala in vivo. Neuropharmacology 40 (2001) 806-817
21. Mayhew T.M., and Gundersen H.J.G. 'If you assume, you can make an ass out of u and me': a decade of the dissector for stereological counting of particles in 3D space. J. Anat. 188 (1996) 1-15
22. Miodonski R. Myeloarchitectonics of the amygdaloid complex of the dog. Acta Biol. Exp. 25 (1965) 263-287
23. Nakaya Y., Kaneko T., Shigemoto R., Nakanishi S., and Mizuno N. Immunohistochemical localization of substance P receptor in the central nervous system of the adult rat. J. Comp. Neurol. 347 (1994) 249-274
24. Napper R.M.A. Total number: a brief review of its importance and its use in assessing cerebellar damage in the rat following early postnatal alcohol exposure. Image Anal. Stereol. 19 (2000) 25-34
25. Nilsson L., Winblad B., Volkmann I., Alafuzoff I., and Bergstrom L. Characterisation and quantification of I-125 Bolton Hunter substance-P binding sites in human brain. Neurochem. Int. 18 (1991) 399-404
26. Perl D.P., Good P.F., Bussière T., Morrison J.H., Erwin J.M., and Hof P.R. Practical approaches to stereology in the setting of aging- and disease-related brain banks. J. Chem. Neuroanat. 20 (2000) 7-19
27. Schmitz C., and Hof P.R. Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach. J. Chem. Neuroanat. 20 (2000) 93-114
28. Shaikh M.B., Steinberg A., and Siegel A. Evidence that substance P is utilized in medial amygdaloid facilitation of defensive rage behavior in the cat. Brain Res. 625 (1993) 283-294
29. Shirayama Y., Mitsushio H., Takashima M., Ichikawa H., and Takahashi K. Reduction of substance P after chronic antidepressants treatment in the striatum, substantia nigra and amygdala of the rat. Brain Res. 739 (1996) 70-78
30. Siegel A., and Schubert K. Neurotransmitters regulating feline aggressive behavior. Rev. Neurosci. 6 (1995) 47-61
31. Smith D.W., Hewson L., Fuller P., Williams A.R., Wheeldon A., and Rupniak N.M.J. The substance P antagonist L-760,735 inhibits stress-induced NK-1 receptor internalisation in the basolateral amygdala. Brain Res. 848 (1999) 90-95
32. Teixeira R.M., Duarte F.S., and De Limba T.C.M. Behavioral and immunological effects of substance P in female and male mice. Pharmacol. Biochem. Behav. 79 (2004) 1-9
33. van der Hart M.G.C., de Biurrun G., Czeh B., Rupniak N.M.J., den Boer J.A., and Fuchs E. Chronic psychosocial stress in tree shrews: effect of the substance P NK1 receptor antagonist L-760735 and clomipramine on endocrine and behavioral parameters. Psychopharmacology 181 (2005) 207-216