Bovine polymerized hemoglobin versus hextend resuscitation in a swine model of severe controlled hemorrhagic shock with delay to definitive care

Shock

Volumn 26, Issue 3, 2006, Pages 302-310

  Rice, Jennifer ^a   Philbin, Nora ^a   McGwin, Gerald ^b   Arnaud, Françoise ^a   Johnson, Todd ^a   Flournoy, W Shannon ^c   Pearce, L Bruce ^d   McCarron, Richard ^a   Kaplan, Lew ^e   Handrigan, Michael ^a   Freilich, Daniel ^a  

^a NAVAL MEDICAL RESEARCH CENTER   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^d Biopure Corporation   (United States)

^e YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

HBOC; Hemorrhage; Pig; Resuscitation; Shock; Trauma

Indexed keywords

BOVINE POLYMERIZED HEMOGLOBIN; HEMOGLOBIN; HETASTARCH; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD TRANSFUSION; CONTROLLED STUDY; DISEASE SEVERITY; HEMODYNAMICS; HEMORRHAGIC SHOCK; LUNG ARTERY PRESSURE; NONHUMAN; OXYGEN TENSION; OXYGEN TISSUE LEVEL; POLYMERIZATION; RECTUS ABDOMINIS MUSCLE; RESUSCITATION; SURVIVAL; SWINE;

ANIMALS; BLOOD PRESSURE; BLOOD SUBSTITUTES; BODY TEMPERATURE; CATTLE; DISEASE MODELS, ANIMAL; FEMALE; FLUID THERAPY; HEART RATE; HEMATOCRIT; HEMOGLOBINS; HETASTARCH; LACTIC ACID; MALE; OXYGEN CONSUMPTION; POLYMERS; RESUSCITATION; SHOCK, HEMORRHAGIC; SURVIVAL ANALYSIS; SWINE; SWINE, MINIATURE; UREA;

EID: 33747370865     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000226338.48033.c2     Document Type: Article

References (27)

1. Davis JW, Parks SN, Kaups KL, Gladen HE, O'Donnell-Nicol S: Admission base deficit predicts transfusion requirements and risk of complications. J Trauma 41:769-774, 1996.
2. Rutherford EJ, Morris JA Jr, Reed GW, Hall KS: Base deficit stratifies mortality and determines therapy. J Trauma 33:417-423, 1992.
3. Manning JE, Katz LM, Pearce LB, Batson DN, McCurdy SL, Gawryl MS, Baker CC: Selective aortic arch perfusion with hemoglobin-based oxygen carrier-201 for resuscitation from exsanguinating cardiac arrest in swine. Crit Care Med 29:2067-2074, 2001.
4. Katz LM, Manning JE, McCurdy S, Pearce LB, Gawryl MS, Wang Y, Brown C: HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury. Resuscitation 54:77-87, 2002.
5. Gurney J, Philbin N, Rice J, Arnaud F, Dong F, Wulster-Radcliffe M, Pearce LB, Kaplan L, McCarron R, Freilich D: A hemoglobin based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in an uncontrolled liver injury hemorrhagic shock swine model with delayed evacuation. 57:726-738, 2004.
6. Philbin N, Rice J, Gurney J, McGwin G, Arnaud F, Dong F, Johnson T, Flournoy WS, Ahlers S, Pearce LB, et al.: A hemoglobin-based oxygen carrier, bovine polymerized hemoglobin (HBOC-201) versus hetastarch (HEX) in a moderate severity hemorrhagic shock swine model with delayed evacuation. Resuscitation 66:367-378, 2005.
7. Sprung J, Kindscher JD, Wahr JA, Levy JH, Monk TG, Moritz MW, O'Hara PJ: The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial. Anesth Analg 94:799-808, 2002. table of contents.
8. Levy JH, Goodnough LT, Greilich PE, Parr GV, Stewart RW, Gratz I, Wahr J, Williams J, Comunale ME, Doblar D, et al.: Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trial. J Thorac Cardiovasc Surg 124:35-42, 2002.
9. Johnson T, Arnaud F, Dong F, Philbin N, Rice J, Asher L, Arrisueno M, Warndorf M, Gurney J, McGwin G, et al.: Bovine polymerized hemoglobin (HBOC-201) resuscitation in three models of hemorrhagic shock with militarily relevant evacuation - effects on histopathology and organ function. Crit Care Med 34:1464-1474, 2006.
10. Sampson JB, Davis MR, Mueller DL, Kashyap VS, Jenkins DH, Kerby JD: A comparison of the hemoglobin-based oxygen carrier HBOC-201 to other low-volume resuscitation fluids in a model of controlled hemorrhagic shock. J Trauma 55:747-754, 2003.
11. York GB, Eggers JS, Smith DL, Jenkins DH, McNeil JD, Mueller D, Josephs JD, Kerby JD: Low-volume resuscitation with a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) provides adequate tissue oxygenation for survival in a porcine model of controlled hemorrhage. J Trauma 55:873-885, 2003.
12. McNeil CJ, Smith LD, Jenkins LD, York MG, Josephs MJ: Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism. J Trauma 50:1063-1075, 2001.
13. Fitzpatrick CM, Savage SA, Kerby JD, Clouse WD, Kashyap VS: Resuscitation with a blood substitute causes vasoconstriction without nitric oxide scavenging in a model of arterial hemorrhage. J Am Coll Surg 199:693-701, 2004.
14. Khan AK, Jahr JS, Nesargi S, Rothenberg SJ, Tang Z, Cheung A, Gunther RA, Kost GJ, Driessen B: Does lead interfere with hemoglobin-based oxygen carrier (HBOC) function? A pilot study of lead concentrations in three approved or tested HBOCs and oxyhemoglobin dissociation with HBOCs and/or bovine blood with varying lead concentrations. Anesth Analg 96:1813-1820, 2003. table of contents.
15. Knudson MM, Lee S, Erickson V, Morabito D, Derugin N, Manley GT: Tissue oxygen monitoring during hemorrhagic shock and resuscitation: a comparison of lactated Ringer's solution, hypertonic saline dextran, and HBOC-201. J Trauma 54:242-252, 2003.
16. Standl T, Freitag M, Burmeister MA, Horn EP, Wilhelm S, Am Esch JS: Hemoglobin-based oxygen carrier HBOC-201 provides higher and faster increase in oxygen tension in skeletal muscle of anemic dogs than do stored red blood cells. J Vasc Surg 37:859-865, 2003.
17. Boura C, Caron A, Longrois D, Mertes PM, Labrude P, Menu P: Volume expansion with modified hemoglobin solution, colloids, or crystalloid after hemorrhagic shock in rabbits: effects in skeletal muscle oxygen pressure and use versus arterial blood velocity and resistance. Shock 19:176-182, 2003.
18. Standl T, Lipfert B, Reeker W, Schulte am Esch J, Lorke DE: Acute effects of complete blood exchange with ultra-purified hemoglobin solution or hydroxyethyl starch on liver and kidney in the animal model. Anasthesiol Intensivmed Notfallmed Schmerzther 31:354-361, 1996.
19. Masuno T, Moore EE, Cheng AM, Moore PK, Grant AR, Johnson JL: Prehospital hemoglobin-based oxygen carrier resuscitation attenuates post-injury acute lung injury. Surgery 138:335-341, 2005.
20. Tatevossian RG, Wo CC, Velmahos GC, Demetriades D, Shoemaker WC: Transcutaneous oxygen and CO2 as early warning of tissue hypoxia and hemodynamic shock in critically ill emergency patients. Crit Care Med 28:2248-2253, 2000.
21. Gulati A, Barve A, Sen AP: Pharmacology of hemoglobin therapeutics. J Lab Clin Med 133:112-119, 1999.
22. Schultz SC, Hamilton IN Jr, Malcolm DS: Use of base deficit to compare resuscitation with lactated Ringer's solution, Haemaccel, whole blood, and diaspirin cross-linked hemoglobin following hemorrhage in rats. J Trauma 35:619-625, 1993. discussion 625-626.
23. Shannon M: Oral Presentation. Army Sponsored Blood Substitute Meeting, WRAMC, Washington, DC, 2003.
24. Viele MK, Weiskopf RB, Fisher D: Recombinant human hemoglobin does not affect renal function in humans: analysis of safety and pharmacokinetics. Anesthesiology 86:848-858, 1997.
25. Sampei K, Ulatowski JA, Asano Y, Kwansa H, Bucci E, Koehler RC: Role of nitric oxide scavenging in vascular response to cell-free hemoglobin transfusion. Am J Physiol Heart Circ Physiol 289:H1191-H1201, 2005.
26. Young MA, Riddez L, Kjellstrom BT, Bursell J, Winslow F, Lohman J, Winslow RM: MalPEG-hemoglobin (MP4) improves hemodynamics, acidbase status, and survival after uncontrolled hemorrhage in anesthetized swine. Crit Care Med 33:1794-1804, 2005.
27. Malhotra AK, Kelly ME, Miller PR, Hartman JC, Fabian TC, Proctor KG: Resuscitation with a novel hemoglobin-based oxygen carrier in a swine model of uncontrolled perioperative hemorrhage. J Trauma 54:915-924, 2003.