Recombinant human hemoglobin does not affect renal function in humans analysis of safety and pharmacokinetics

Anesthesiology

Volumn 86, Issue 4, 1997, Pages 848-858

  Viele, Maurene K ^a,b,c   Weiskopf, Richard B ^a,b   Fisher, Dennis ^a,b  

^a Department of Laboratory Medicine ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Hemoglobin, recombinant: Safety; renal; Hemoglobin, recombinant: Side effects; Nonmem: Population techniques; Pharmacokinetics: Hemoglobin

Indexed keywords

CREATININE; HEMOGLOBIN; HUMAN SERUM ALBUMIN; N ACETYL BETA GLUCOSAMINIDASE; OPTROD; RECOMBINANT HEMOGLOBIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BACKACHE; CHILL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG SAFETY; FEVER; GASTROINTESTINAL TOXICITY; HEADACHE; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY FUNCTION; MALE; NORMAL HUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADOLESCENT; ADULT; BLOOD PRESSURE; CREATININE; HEART RATE; HEMOGLOBINS; HUMANS; KIDNEY; MALE; METABOLIC CLEARANCE RATE; NITRIC OXIDE; RECOMBINANT PROTEINS;

EID: 0030944331     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199704000-00015     Document Type: Article

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