-
1
-
-
0033917833
-
Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries
-
Bartsevich V.V., and Juliano R.L. Regulation of the MDR1 gene by transcriptional repressors selected using peptide combinatorial libraries. Mol. Pharmacol. 58 (2000) 1-10
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 1-10
-
-
Bartsevich, V.V.1
Juliano, R.L.2
-
2
-
-
0142165907
-
Engineered zinc finger proteins for controlling stem cell fate
-
Bartsevich V.V., Miller J.C., Case C.C., and Pabo C.O. Engineered zinc finger proteins for controlling stem cell fate. Stem Cells 21 (2003) 632-637
-
(2003)
Stem Cells
, vol.21
, pp. 632-637
-
-
Bartsevich, V.V.1
Miller, J.C.2
Case, C.C.3
Pabo, C.O.4
-
3
-
-
0034652141
-
Positive and negative regulation of endogenous genes by designed transcription factors
-
Beerli R.R., Dreier B., and Barbas III C.F. Positive and negative regulation of endogenous genes by designed transcription factors. Proc. Natl. Acad. Sci. USA 97 (2000) 1495-1500
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1495-1500
-
-
Beerli, R.R.1
Dreier, B.2
Barbas III, C.F.3
-
4
-
-
0037315952
-
Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene
-
Falke D., Fisher M., Ye D., and Juliano R.L. Design of artificial transcription factors to selectively regulate the pro-apoptotic bax gene. Nucleic Acids Res. 31 (2003) e10
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Falke, D.1
Fisher, M.2
Ye, D.3
Juliano, R.L.4
-
5
-
-
0036792099
-
Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors
-
Guan X., Stege J., Kim M., Dahmani Z., Fan N., Heifetz P., Barbas III C.F., and Briggs S.P. Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors. Proc. Natl. Acad. Sci. USA 99 (2002) 13296-13301
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13296-13301
-
-
Guan, X.1
Stege, J.2
Kim, M.3
Dahmani, Z.4
Fan, N.5
Heifetz, P.6
Barbas III, C.F.7
Briggs, S.P.8
-
6
-
-
0344284577
-
Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors
-
Jouvenot Y., Ginjala V., Zhang L., Liu P.Q., Oshimura M., Feinberg A.P., Wolffe A.P., Ohlsson R., and Gregory P.D. Targeted regulation of imprinted genes by synthetic zinc-finger transcription factors. Gene Ther. 10 (2003) 513-522
-
(2003)
Gene Ther.
, vol.10
, pp. 513-522
-
-
Jouvenot, Y.1
Ginjala, V.2
Zhang, L.3
Liu, P.Q.4
Oshimura, M.5
Feinberg, A.P.6
Wolffe, A.P.7
Ohlsson, R.8
Gregory, P.D.9
-
7
-
-
0035815697
-
Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A
-
Liu P.Q., Rebar E.J., Zhang L., Liu Q., Jamieson A.C., Liang Y., Qi H., Li P.X., Chen B., Mendel M.C., Zhong X., Lee Y.L., Eisenberg S.P., Spratt S.K., Case C.C., and Wolffe A.P. Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A. J. Biol. Chem. 276 (2001) 11323-11334
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 11323-11334
-
-
Liu, P.Q.1
Rebar, E.J.2
Zhang, L.3
Liu, Q.4
Jamieson, A.C.5
Liang, Y.6
Qi, H.7
Li, P.X.8
Chen, B.9
Mendel, M.C.10
Zhong, X.11
Lee, Y.L.12
Eisenberg, S.P.13
Spratt, S.K.14
Case, C.C.15
Wolffe, A.P.16
-
8
-
-
0036912846
-
Induction of angiogenesis in a mouse model using engineered transcription factors
-
Rebar E.J., Huang Y., Hickey R., Nath A.K., Meoli D., Nath S., Chen B., Xu L., Liang Y., Jamieson A.C., Zhang L., Spratt S.K., Case C.C., Wolffe A., and Giordano F.J. Induction of angiogenesis in a mouse model using engineered transcription factors. Nat. Med. 8 (2002) 1427-1432
-
(2002)
Nat. Med.
, vol.8
, pp. 1427-1432
-
-
Rebar, E.J.1
Huang, Y.2
Hickey, R.3
Nath, A.K.4
Meoli, D.5
Nath, S.6
Chen, B.7
Xu, L.8
Liang, Y.9
Jamieson, A.C.10
Zhang, L.11
Spratt, S.K.12
Case, C.C.13
Wolffe, A.14
Giordano, F.J.15
-
9
-
-
0037164741
-
Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo
-
Snowden A.W., Gregory P.D., Case C.C., and Pabo C.O. Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo. Curr. Biol. 12 (2002) 2159-2166
-
(2002)
Curr. Biol.
, vol.12
, pp. 2159-2166
-
-
Snowden, A.W.1
Gregory, P.D.2
Case, C.C.3
Pabo, C.O.4
-
10
-
-
9144250992
-
Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors
-
Snowden A.W., Zhang L., Urnov F., Dent C., Jouvenot Y., Zhong X., Rebar E.J., Jamieson A.C., Zhang H.S., Tan S., Case C.C., Pabo C.O., Wolffe A.P., and Gregory P.D. Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. Cancer Res. 63 (2003) 8968-8976
-
(2003)
Cancer Res.
, vol.63
, pp. 8968-8976
-
-
Snowden, A.W.1
Zhang, L.2
Urnov, F.3
Dent, C.4
Jouvenot, Y.5
Zhong, X.6
Rebar, E.J.7
Jamieson, A.C.8
Zhang, H.S.9
Tan, S.10
Case, C.C.11
Pabo, C.O.12
Wolffe, A.P.13
Gregory, P.D.14
-
11
-
-
0142027810
-
Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity
-
Tan S., Guschin D., Davalos A., Lee Y.L., Snowden A.W., Jouvenot Y., Zhang H.S., Howes K., McNamara A.R., Lai A., Ullman C., Reynolds L., Moore M., Isalan M., Berg L.P., Campos B., Qi H., Spratt S.K., Case C.C., Pabo C.O., Campisi J., and Gregory P.D. Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity. Proc. Natl. Acad. Sci. USA 100 (2003) 11997-12002
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 11997-12002
-
-
Tan, S.1
Guschin, D.2
Davalos, A.3
Lee, Y.L.4
Snowden, A.W.5
Jouvenot, Y.6
Zhang, H.S.7
Howes, K.8
McNamara, A.R.9
Lai, A.10
Ullman, C.11
Reynolds, L.12
Moore, M.13
Isalan, M.14
Berg, L.P.15
Campos, B.16
Qi, H.17
Spratt, S.K.18
Case, C.C.19
Pabo, C.O.20
Campisi, J.21
Gregory, P.D.22
more..
-
12
-
-
0034721877
-
Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene
-
Zhang L., Spratt S.K., Liu Q., Johnstone B., Qi H., Raschke E.E., Jamieson A.C., Rebar E.J., Wolffe A.P., and Case C.C. Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene. J. Biol. Chem. 275 (2000) 33850-33860
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33850-33860
-
-
Zhang, L.1
Spratt, S.K.2
Liu, Q.3
Johnstone, B.4
Qi, H.5
Raschke, E.E.6
Jamieson, A.C.7
Rebar, E.J.8
Wolffe, A.P.9
Case, C.C.10
-
14
-
-
0024637847
-
Transcriptional control of Drosophila fushi tarazu zebra stripe expression
-
Dearolf C.R., Topol J., and Parker C.S. Transcriptional control of Drosophila fushi tarazu zebra stripe expression. Genes Dev. 3 (1989) 384-398
-
(1989)
Genes Dev.
, vol.3
, pp. 384-398
-
-
Dearolf, C.R.1
Topol, J.2
Parker, C.S.3
-
15
-
-
0025395215
-
Transcriptional regulation of the Drosophila segmentation gene fushi tarazu (ftz)
-
Dearolf C.R., Topol J., and Parker C.S. Transcriptional regulation of the Drosophila segmentation gene fushi tarazu (ftz). Bioessays 12 (1990) 109-113
-
(1990)
Bioessays
, vol.12
, pp. 109-113
-
-
Dearolf, C.R.1
Topol, J.2
Parker, C.S.3
-
16
-
-
0023651350
-
Regulation and function of the Drosophila segmentation gene fushi tarazu
-
Hiromi Y., and Gehring W.J. Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell 50 (1987) 963-974
-
(1987)
Cell
, vol.50
, pp. 963-974
-
-
Hiromi, Y.1
Gehring, W.J.2
-
17
-
-
0022317468
-
Control elements of the Drosophila segmentation gene fushi tarazu
-
Hiromi Y., Kuroiwa A., and Gehring W.J. Control elements of the Drosophila segmentation gene fushi tarazu. Cell 43 (1985) 603-613
-
(1985)
Cell
, vol.43
, pp. 603-613
-
-
Hiromi, Y.1
Kuroiwa, A.2
Gehring, W.J.3
-
18
-
-
0031953828
-
Chromatin remodeling mediated by Drosophila GAGA factor and ISWI activates fushi tarazu gene transcription in vitro
-
Okada M., and Hirose S. Chromatin remodeling mediated by Drosophila GAGA factor and ISWI activates fushi tarazu gene transcription in vitro. Mol. Cell. Biol. 18 (1998) 2455-2461
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 2455-2461
-
-
Okada, M.1
Hirose, S.2
-
19
-
-
0023474132
-
Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes
-
DiNardo S., and O'Farrell P.H. Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes. Genes Dev. 1 (1987) 1212-1225
-
(1987)
Genes Dev.
, vol.1
, pp. 1212-1225
-
-
DiNardo, S.1
O'Farrell, P.H.2
-
20
-
-
0021139598
-
Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins
-
Laughon A., and Scott M.P. Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins. Nature 310 (1984) 25-31
-
(1984)
Nature
, vol.310
, pp. 25-31
-
-
Laughon, A.1
Scott, M.P.2
-
21
-
-
0032963909
-
Kinetic analysis of segmentation gene interactions in Drosophila embryos
-
Nasiadka A., and Krause H.M. Kinetic analysis of segmentation gene interactions in Drosophila embryos. Development 126 (1999) 1515-1526
-
(1999)
Development
, vol.126
, pp. 1515-1526
-
-
Nasiadka, A.1
Krause, H.M.2
-
22
-
-
0026761537
-
Concentration-dependent activities of the even-skipped protein in Drosophila embryos
-
Manoukian A.S., and Krause H.M. Concentration-dependent activities of the even-skipped protein in Drosophila embryos. Genes Dev. 6 (1992) 1740-1751
-
(1992)
Genes Dev.
, vol.6
, pp. 1740-1751
-
-
Manoukian, A.S.1
Krause, H.M.2
-
23
-
-
0021326563
-
Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogaster
-
Wakimoto B.T., Turner F.R., and Kaufman T.C. Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogaster. Dev. Biol. 102 (1984) 147-172
-
(1984)
Dev. Biol.
, vol.102
, pp. 147-172
-
-
Wakimoto, B.T.1
Turner, F.R.2
Kaufman, T.C.3
-
24
-
-
0031875658
-
Doxycycline-induced transgene expression during Drosophila development and aging
-
Bieschke E.T., Wheeler J.C., and Tower J. Doxycycline-induced transgene expression during Drosophila development and aging. Mol. Gen. Genet. 258 (1998) 571-579
-
(1998)
Mol. Gen. Genet.
, vol.258
, pp. 571-579
-
-
Bieschke, E.T.1
Wheeler, J.C.2
Tower, J.3
-
25
-
-
0034796382
-
A Drosophila MBD family member is a transcriptional corepressor associated with specific genes
-
Ballestar E., Pile L.A., Wassarman D.A., Wolffe A.P., and Wade P.A. A Drosophila MBD family member is a transcriptional corepressor associated with specific genes. Eur. J. Biochem. 268 (2001) 5397-5406
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 5397-5406
-
-
Ballestar, E.1
Pile, L.A.2
Wassarman, D.A.3
Wolffe, A.P.4
Wade, P.A.5
-
26
-
-
0033826338
-
Transcriptional repression by Drosophila methyl-CpG-binding proteins
-
Roder K., Hung M.S., Lee T.L., Lin T.Y., Xiao H., Isobe K.I., Juang J.L., and Shen C.J. Transcriptional repression by Drosophila methyl-CpG-binding proteins. Mol. Cell. Biol. 20 (2000) 7401-7409
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7401-7409
-
-
Roder, K.1
Hung, M.S.2
Lee, T.L.3
Lin, T.Y.4
Xiao, H.5
Isobe, K.I.6
Juang, J.L.7
Shen, C.J.8
-
27
-
-
20244385424
-
Drosophila p53 is a structural and functional homolog of the tumor suppressor p53
-
Ollmann M., Young L.M., Di Como C.J., Karim F., Belvin M., Robertson S., Whittaker K., Demsky M., Fisher W.W., Buchman A., Duyk G., Friedman L., Prives C., and Kopczynski C. Drosophila p53 is a structural and functional homolog of the tumor suppressor p53. Cell 101 (2000) 91-101
-
(2000)
Cell
, vol.101
, pp. 91-101
-
-
Ollmann, M.1
Young, L.M.2
Di Como, C.J.3
Karim, F.4
Belvin, M.5
Robertson, S.6
Whittaker, K.7
Demsky, M.8
Fisher, W.W.9
Buchman, A.10
Duyk, G.11
Friedman, L.12
Prives, C.13
Kopczynski, C.14
-
29
-
-
0035042173
-
Establishment and maintenance of parasegmental compartments
-
Hughes S.C., and Krause H.M. Establishment and maintenance of parasegmental compartments. Development 128 (2001) 1109-1118
-
(2001)
Development
, vol.128
, pp. 1109-1118
-
-
Hughes, S.C.1
Krause, H.M.2
-
30
-
-
0029328435
-
Programmed cell death in the Drosophila central nervous system midline
-
Zhou L., Hashimi H., Schwartz L.M., and Nambu J.R. Programmed cell death in the Drosophila central nervous system midline. Curr. Biol. 5 (1995) 784-790
-
(1995)
Curr. Biol.
, vol.5
, pp. 784-790
-
-
Zhou, L.1
Hashimi, H.2
Schwartz, L.M.3
Nambu, J.R.4
-
31
-
-
0025226109
-
Mutations affecting the stability of the fushi tarazu protein of Drosophila
-
Kellerman K.A., Mattson D.M., and Duncan I. Mutations affecting the stability of the fushi tarazu protein of Drosophila. Genes Dev. 4 (1990) 1936-1950
-
(1990)
Genes Dev.
, vol.4
, pp. 1936-1950
-
-
Kellerman, K.A.1
Mattson, D.M.2
Duncan, I.3
-
32
-
-
0025794147
-
Synthetic oligonucleotides recreate Drosophila fushi tarazu zebra-stripe expression
-
Topol J., Dearolf C.R., Prakash K., and Parker C.S. Synthetic oligonucleotides recreate Drosophila fushi tarazu zebra-stripe expression. Genes Dev. 5 (1991) 855-867
-
(1991)
Genes Dev.
, vol.5
, pp. 855-867
-
-
Topol, J.1
Dearolf, C.R.2
Prakash, K.3
Parker, C.S.4
-
33
-
-
0023697252
-
GAL4-VP16 is an unusually potent transcriptional activator
-
Sadowski I., Ma J., Triezenberg S., and Ptashne M. GAL4-VP16 is an unusually potent transcriptional activator. Nature 335 (1988) 563-564
-
(1988)
Nature
, vol.335
, pp. 563-564
-
-
Sadowski, I.1
Ma, J.2
Triezenberg, S.3
Ptashne, M.4
-
34
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand A.H., and Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118 (1993) 401-415
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
35
-
-
0024553104
-
Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression
-
Ish-Horowicz D., Pinchin S.M., Ingham P.W., and Gyurkovics H.G. Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression. Cell 57 (1989) 223-232
-
(1989)
Cell
, vol.57
, pp. 223-232
-
-
Ish-Horowicz, D.1
Pinchin, S.M.2
Ingham, P.W.3
Gyurkovics, H.G.4
-
36
-
-
0027375250
-
Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila
-
Zhao J.J., and Pick L. Generating loss-of-function phenotypes of the fushi tarazu gene with a targeted ribozyme in Drosophila. Nature 365 (1993) 448-451
-
(1993)
Nature
, vol.365
, pp. 448-451
-
-
Zhao, J.J.1
Pick, L.2
-
37
-
-
0022382428
-
Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz
-
Struhl G. Near-reciprocal phenotypes caused by inactivation or indiscriminate expression of the Drosophila segmentation gene ftz. Nature 318 (1985) 677-680
-
(1985)
Nature
, vol.318
, pp. 677-680
-
-
Struhl, G.1
-
38
-
-
0029671035
-
Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide
-
Copeland J.W., Nasiadka A., Dietrich B.H., and Krause H.M. Patterning of the Drosophila embryo by a homeodomain-deleted Ftz polypeptide. Nature 379 (1996) 162-165
-
(1996)
Nature
, vol.379
, pp. 162-165
-
-
Copeland, J.W.1
Nasiadka, A.2
Dietrich, B.H.3
Krause, H.M.4
-
39
-
-
0034672095
-
DNA of Drosophila melanogaster contains 5-methylcytosine
-
Gowher H., Leismann O., and Jeltsch A. DNA of Drosophila melanogaster contains 5-methylcytosine. EMBO J. 19 (2000) 6918-6923
-
(2000)
EMBO J.
, vol.19
, pp. 6918-6923
-
-
Gowher, H.1
Leismann, O.2
Jeltsch, A.3
-
40
-
-
0034735780
-
DNA methylation in Drosophila melanogaster
-
Lyko F., Ramsahoye B.H., and Jaenisch R. DNA methylation in Drosophila melanogaster. Nature 408 (2000) 538-540
-
(2000)
Nature
, vol.408
, pp. 538-540
-
-
Lyko, F.1
Ramsahoye, B.H.2
Jaenisch, R.3
-
41
-
-
0033946982
-
Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1
-
Fujita N., Shimotake N., Ohki I., Chiba T., Saya H., Shirakawa M., and Nakao M. Mechanism of transcriptional regulation by methyl-CpG binding protein MBD1. Mol. Cell. Biol. 20 (2000) 5107-5118
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 5107-5118
-
-
Fujita, N.1
Shimotake, N.2
Ohki, I.3
Chiba, T.4
Saya, H.5
Shirakawa, M.6
Nakao, M.7
-
42
-
-
0035542974
-
Methyl CpG-binding proteins and transcriptional repression
-
Wade P.A. Methyl CpG-binding proteins and transcriptional repression. Bioessays 23 (2001) 1131-1137
-
(2001)
Bioessays
, vol.23
, pp. 1131-1137
-
-
Wade, P.A.1
|