Short-term treatment with zanamivir to prevent influenza: Results of a placebo-controlled study

Clinical Infectious Diseases

Volumn 30, Issue 3, 2000, Pages 587-589

  Kaiser, Laurent ^a   Henry, Dan ^b   Flack, Nancy P ^c   Keene, Oliver ^d   Hayden, Frederick G ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b Foothill Family Clinic   (United States)

^c GLAXOSMITHKLINE   (United States)

^d GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ZANAMIVIR;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG TOLERABILITY; FATIGUE; FEMALE; HEADACHE; HUMAN; INFECTION PREVENTION; INFECTION RATE; INFLUENZA; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, INHALATION; ADMINISTRATION, INTRANASAL; ADOLESCENT; ADULT; AGED; ANTIVIRAL AGENTS; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; GUANIDINES; HUMANS; INFLUENZA, HUMAN; MALE; MIDDLE AGED; PYRANS; SIALIC ACIDS; TREATMENT OUTCOME; ZANAMIVIR;

EID: 0034074146     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/313696     Document Type: Article

References (7)

1. 1. Hayden FG, Osterhaus AD, Treanor JJ, et al. Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenza virus infections. N Engl J Med 1997; 337:874-9.
2. 2. The MIST (Management of Influenza in the Southern Hemisphere Trialists) Study Group. Randomised trial of efficacy and safety of inhaled zanamivir in treatment of influenza A and B infections. Lancet 1998; 352:1877-81.
3. 3. Hayden FG, Treanor JJ, Betts RF, Lobo M, Esinhart JD, Hussey EK. Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza. JAMA 1996; 275:295-9.
4. 4. Monto AS, Robinson DP, Herlocher L, Hinson JM, Elliott M, Crisp A. Zanamivir in the prevention of influenza among healthy adults: a randomized controlled trial. JAMA 1999; 282:31-5.
5. 5. Hayden FG, Atmar RL, Schilling M, et al. Use of selective oral neuraminidase inhibitor oseltamivir to prevent influenza. N Engl J Med 1999; 341:1336-43.
6. 6. Hayden FG, Palese PA. Influenza virus. In: Richman DD, Whitley RJ, Hayden FG, eds. Clinical virology. New York: Churchill Livingstone, 1997:911-42.
7. 7. Tannock GA, Gillett SM, Gillet RS, et al. A study of intranasally administered interferon A (rIFN-alpha2) for the seasonal prophylaxis of natural infections of the upper respiratory tract in healthy volunteers. Epidemiol Infect 1988; 101:611-21.