Transdermal delivery of ketoprofen: The influence of drug- dioleylphosphatidylcholine interactions

Pharmaceutical Research

Volumn 23, Issue 8, 2006, Pages 1776-1785

  Garcia, Maria Teresa Junqueira ^a   De Paula Da Silva, Carlos Henrique Tomich ^a   De Oliveira, Dionéia C R ^a   Braga, Eliane Candiane Arantes ^a   Thomazini, José Antônio ^a   Lopes Badra Bentley, Maria Vitória ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Dioleylphosphatidylcholine; Drug complex; Ketoprofen; Skin permeation; Skin toxicity; Transdermal delivery

Indexed keywords

CHLOROFORM; DIOLEOYLPHOSPHATIDYLCHOLINE; KETOPROFEN; MINERAL OIL; NITROGEN; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING KINETICS; DENSITY FUNCTIONAL THEORY; DIFFERENTIAL SCANNING CALORIMETRY; DIPOLE; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG HYPERSENSITIVITY; DRUG PENETRATION; DRUG SOLUBILITY; ENTHALPY; FEMALE; GEOMETRY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SKIN IRRITATION; SKIN PERMEABILITY; SKIN TOXICITY; SWINE; TEMPERATURE;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CALORIMETRY, DIFFERENTIAL SCANNING; CHEMISTRY, PHARMACEUTICAL; EDEMA; EXCIPIENTS; FEMALE; KETOPROFEN; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, HAIRLESS; MICE, INBRED BALB C; MICE, INBRED HRS; MODELS, MOLECULAR; PHOSPHATIDYLCHOLINES; SKIN; SKIN ABSORPTION; SOLUBILITY; SWINE;

EID: 33746898697     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-006-9040-3     Document Type: Article

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