Imaging of multiple mRNA targets using quantum dot based in situ hybridization and spectral deconvolution in clinical biopsies

Biochemical and Biophysical Research Communications

Volumn 348, Issue 2, 2006, Pages 628-636

  Tholouli, Eleni ^a   Hoyland, Judith A ^b   Di Vizio, Dolores ^c   O'Connell, Fionnuala ^c   MacDermott, Sarah A ^b   Twomey, David ^d   Levenson, Richard ^e   Yin, John A Liu ^a   Golub, Todd R ^d   Loda, Massimo ^c   Byers, Richard ^b  

^a MANCHESTER ROYAL INFIRMARY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Cambridge Research & Instrumentation Inc   (United States)

Author keywords

Bone marrow biopsies; In situ hybridization; Messenger RNA detection; Multiplex in situ hybridization; Quantum dots; Spectral deconvolution

Indexed keywords

FLUOROCHROME; MESSENGER RNA; MYELOPEROXIDASE; OLIGONUCLEOTIDE; PARAFFIN; PROTEIN BCL 2; QUANTUM DOT; SURVIVIN; X LINKED INHIBITOR OF APOPTOSIS;

ACUTE LEUKEMIA; ARTICLE; BONE MARROW BIOPSY; CONTROLLED STUDY; FOLLICULAR LYMPHOMA; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HISTOLOGY; HUMAN; HUMAN TISSUE; IMAGING; IN SITU HYBRIDIZATION; NUCLEOTIDE SEQUENCE; OLIGONUCLEOTIDE PROBE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RNA ANALYSIS; SEPARATION TECHNIQUE; SPECTROSCOPY;

BIOPSY; FIXATIVES; FORMALDEHYDE; GENE EXPRESSION PROFILING; HUMANS; IN SITU HYBRIDIZATION; OLIGONUCLEOTIDE PROBES; QUANTUM DOTS; RNA, MESSENGER;

EID: 33746885087     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.07.122     Document Type: Article

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