메뉴 건너뛰기




Volumn 32, Issue 6, 2006, Pages 687-697

Preformulation studies on Imexon

Author keywords

General acid base catalysis; Imexon; pH stability; Preformulation studies; Solubility

Indexed keywords

AZIRIDINE; BUFFER; HYDROGEN PEROXIDE; IMEXON; SODIUM CHLORIDE;

EID: 33746845625     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.1080/03639040600599830     Document Type: Article
Times cited : (11)

References (17)
  • 1
    • 0023941036 scopus 로고
    • Preformulation solubility and kinetic studies of 2′,3′- dideoxypurine nucleosides: Potential anti-AIDS agents
    • Anderson, B. D., Wygant, M. B., Xiang, T., Waugh, W. A., & Stella. V. J. (1988) Preformulation solubility and kinetic studies of 2′,3′- dideoxypurine nucleosides: potential anti-AIDS agents. Int. J. Pharm., 45, 27-37.
    • (1988) Int. J. Pharm. , vol.45 , pp. 27-37
    • Anderson, B.D.1    Wygant, M.B.2    Xiang, T.3    Waugh, W.A.4    Stella, V.J.5
  • 4
    • 20644466654 scopus 로고    scopus 로고
    • LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products
    • Den Brok, M. W. J., Nuijen, B., Hillebrand, M. J. X., Lutz, C., Opitz, H., & Beijnen, J. H. (2005a) LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products. J. Pharm. Biomed., 38, 686-694.
    • (2005) J. Pharm. Biomed. , vol.38 , pp. 686-694
    • Den Brok, M.W.J.1    Nuijen, B.2    Hillebrand, M.J.X.3    Lutz, C.4    Opitz, H.5    Beijnen, J.H.6
  • 5
    • 20344400666 scopus 로고    scopus 로고
    • Pharmaceutical development of a lyophilized dosage form for the investigational anticancer agent imexon using dimethyl sulfoxide as a solubilizing and stabilizing agent
    • Den Brok, M. W. J., Nuijen, B., Lutz, C., Opitz, H., & Beijnen, J. H. (2005b) Pharmaceutical development of a lyophilized dosage form for the investigational anticancer agent imexon using dimethyl sulfoxide as a solubilizing and stabilizing agent. J. Pharm. Sci., 94 (5), 1101-1114.
    • (2005) J. Pharm. Sci. , vol.94 , Issue.5 , pp. 1101-1114
    • Den Brok, M.W.J.1    Nuijen, B.2    Lutz, C.3    Opitz, H.4    Beijnen, J.H.5
  • 6
    • 0034666730 scopus 로고    scopus 로고
    • Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent Imexon
    • Dvorakova, K., Payne, C. M., Tome, M. E., Briehl, M. M., McClure, T., & Dorr, R. T. (2000) Induction of oxidative stress and apoptosis in myeloma cells by the aziridine-containing agent Imexon. Biochem. Pharmacol., 60, 749-758.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 749-758
    • Dvorakova, K.1    Payne, C.M.2    Tome, M.E.3    Briehl, M.M.4    McClure, T.5    Dorr, R.T.6
  • 9
    • 0031889315 scopus 로고    scopus 로고
    • A Kinetic Oxymoron: Concentration-Dependent First-order rate constants for hydrolysis of Ceftazidime
    • Fubara, J. O., & Notari, R. E. (1998) A Kinetic Oxymoron: Concentration-Dependent First-order rate constants for hydrolysis of Ceftazidime. J. Pharm. Sci., 87(1), 53-58.
    • (1998) J. Pharm. Sci. , vol.87 , Issue.1 , pp. 53-58
    • Fubara, J.O.1    Notari, R.E.2
  • 10
    • 12844283957 scopus 로고    scopus 로고
    • High-throughput drug discovery: What can we expect from HTS?
    • Gribbon, P., & Sewing, A. (2005) High-throughput drug discovery: what can we expect from HTS? Drug Discovery Today, 10 (1), 17-22
    • (2005) Drug Discovery Today , vol.10 , Issue.1 , pp. 17-22
    • Gribbon, P.1    Sewing, A.2
  • 12
    • 0346100660 scopus 로고    scopus 로고
    • Chemical basis for the biological activity of Imexon and related Cyanaziridines
    • Iyengar, B. S., Dorr, R. T., & Remers, W. A. (2004) Chemical basis for the biological activity of Imexon and related Cyanaziridines. J. Med. Chem., 47, 218-223.
    • (2004) J. Med. Chem. , vol.47 , pp. 218-223
    • Iyengar, B.S.1    Dorr, R.T.2    Remers, W.A.3
  • 14
    • 0037027877 scopus 로고    scopus 로고
    • Stabilization and preformulation of anticancer drug-SarCNU
    • Ni, N., Sanghvi, T., & Yalkowsky, S. H. (2002) Stabilization and preformulation of anticancer drug-SarCNU. Int. J. Pharm., 249, 257-264.
    • (2002) Int. J. Pharm. , vol.249 , pp. 257-264
    • Ni, N.1    Sanghvi, T.2    Yalkowsky, S.H.3
  • 15
    • 15044340742 scopus 로고    scopus 로고
    • Accelerated aging: Prediction of chemical stability of pharmaceuticals
    • Waterman, K. C., Adami, R. C. (2005) Accelerated aging: prediction of chemical stability of pharmaceuticals. Int. J. Pharm., 293, 101-125.
    • (2005) Int. J. Pharm. , vol.293 , pp. 101-125
    • Waterman, K.C.1    Adami, R.C.2
  • 17
    • 0036124717 scopus 로고    scopus 로고
    • Preforumlation Studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability
    • Zhu, H., Meserve, K., & Floyd, E. (2002) Preforumlation Studies for an ultrashort-acting neuromuscular blocking agent GW280430A. I. Buffer and cosolvent effects on the solution stability. Drug Dev. Int. Pharm., 28(2), 135-142.
    • (2002) Drug Dev. Int. Pharm. , vol.28 , Issue.2 , pp. 135-142
    • Zhu, H.1    Meserve, K.2    Floyd, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.